Effect of the ripening stage on the mechanical, acoustics, and food oral processing properties of apples by Ana Sredojevic, Dragan Radivojevic, Steva Levic, Milica Fotiric Aksic, Jasminka Milivojevic, Slavica Spasojevic, Ilija Djekic

“…Braeburn apples required fewer chews (under 20) and shorter mastication time (12–14 s), whereas Golden Delicious needed more chews (over 25) and longer mastication time (15–22 s), with significant differences across shelf-life. …”
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Temporal trends of a cellular host response test for sepsis and a comparison with selected biomarkers of inflammation and infection by Matthew S. Berlinger, Matt Sorrells, Christopher B. Thomas, Tonya Jagneaux, James E. Walker, Jennifer Daigle, Heather Quiriarte, Youyoung Kim, Guillaume Spielmann, Debbie Robertson, Susan Park Ochsner, Gideon Avornu, Katherine Fenstermacher, Elijah James Kurien, Camille King, Adenine Cembellin-Kao, Chase Yonamine, Querino Maia, Maciej Obrebski, David N. Hager, Roya Sheybani, Henry T. K. Tse, Ajay M. Shah, Robert Scoggins, Hollis R. O’Neal, Richard Rothman

“…ISI also provided more stable and timely disease state assessments compared to traditional biomarkers (PCT, CRP, IL-6, and neutrophil elastase). Larger studies are needed to validate these findings and assess ISI’s clinical utility as a prognosticator of sepsis progression and treatment response.…”
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Long-term follow-up of anti-IFN-α2 autoantibody levels in hospitalized individuals with COVID-19 by Maaike Cockx, Nick Geukens, Birthe Michiels, Doreen Dillaerts, Eveline Claeys, Olivia Vandekerckhove, Natalie Lorent, Xavier Bossuyt

“…Additional large studies are needed to study the potential role of loss of tolerance after SARS-CoV-2 infection in long COVID.…”
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Integrating bioinformatics with network pharmacology and experimental validation analysis to reveal the pharmacological mechanism of Ma-xing-shi-gan-tang in treating viral pneumoni... by Li Huie, Wang Qiong, An Huijie, Zhang Qiang, Du Wei, Jiao Ying, Pan Siwei, Ding Huihui, Luo Aiwu

“…However, the mechanism of treating viral pneumonia still needs to be elucidated. In this study, network pharmacology has been used to explore the therapeutic effects and therapeutic targets of MXSGT and bioactive compounds. …”
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The interaction of solar radiation modification with Earth system tipping elements by G. Futerman, M. Adhikari, A. Duffey, Y. Fan, J. Gurevitch, P. Irvine, C. Wieners

“…We then briefly assess whether SRM could halt or reverse tipping once feedbacks have been initiated. Finally, we suggest pathways for further research. …”
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Ecological and evolutionary consequences of ploidy-driven trait variation: insights from Saxifraga oppositifolia L. by Pernille Bronken Eidesen, Anne Krag Brysting, Kathleen Rani Hagen, Simen Salomonsen Hjelle, Aloïs Revéret, Ingrid Vesterdal Tjessem, Martin Čertner, Jorge Gago, Mie Prik Arnberg, Johanna Behrisch, Katrín Björnsdóttir, Viktorie Brožová, Angeline J.H.M. Bruls, Kathrin Driehaus, Janna Einöder, Ragnhild Gya, Valentina Handle, Niki Meinert Hansen, Maria Huntsaar, Anne Hølmkjær Jacobsen, Kayden Kendrick, Christine Mikalsen, Eike Müller, Sondre Kaastad Sørsdal, Jóhannes Bjarki Urbancic Tómasson, Inger Kristine Volden

“…Autopolyploidy has significantly influenced both ecology and evolution of S. oppositifolia and needs to be accounted for when autopolyploids are used as a study species or evaluated for management purposes. …”
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Developing and evaluating a gamified self-management application for inflammatory bowel disease using the ADDIE model and Sukr framework by Narges Norouzkhani, Somaye Norouzi, Mahbobeh Faramarzi, Ali Bahari, Javad Shokri Shirvani, Saeid Eslami, Hamed Tabesh

“…As the essential part of treatments approach, patient adherence to treatment protocols and self-management practices are crucial to = IBD management. Healthcare initiatives focused on chronic conditions are strongly needed to consider various aspects of gamification and how it can positively affect self-management. …”
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Associations of serum uric acid, risk of atherosclerotic cardiovascular disease, and mortality: results from NHANES by Rundong Chen, Miao Pang, Yilei Zhang, Hongjian Zhang, Guanghao Zhang, Yutian Wei, Weilong Hua, Xiaoxi Zhang, Lei Zhang, Zifu Li, Qiang Li, Pengfei Yang

“…However, further research is needed to better understand how SUA affects ASCVD and its underlying mechanisms.…”
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Recent advances and challenges in solid sorbents for CO2 capture by Hamid Zentou, Bosirul Hoque, Mahmoud A. Abdalla, Ahmed F. Saber, Omar Y. Abdelaziz, Mansur Aliyu, Abdullah M. Alkhedhair, Abdullah J. Alabduly, Mahmoud M. Abdelnaby

“…Carbon capture is still a crucial technology for lowering CO₂ emissions, especially since fossil fuels persist in supplying a considerable share of global energy needs. Among different capture techniques, solid sorbents like activated carbon, zeolites, metal-organic frameworks (MOFs), and porous organic polymers (POPs) are becoming prominent due to their excellent adsorption effectiveness, durability, and ease of operation. …”
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A systematic review of the effectiveness of technological interventions for caregivers of people with dementia: effects on quality of life and psychoemotional variables by Patricia Ferrero-Sereno, Patricia Ferrero-Sereno, María Mendoza-Muñoz, Patricia Palomo-López, Jorge Carlos-Vivas, Patricia Luna-Castaño, Raquel Caballero-De la Calle, Miguel Ángel García-Garrido, Laura Muñoz-Bermejo

“…Therefore, more research is needed to further investigate these methodologies in order to optimize their impact and adapt them to the diverse realities of caregivers of people with dementia.…”
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Prosocial behavior in convicted offenders: A scoping review by Liliana HUREZAN, Sara Maria JUGANARU, Ioana-Anastasia GORAN, Elena Emanuela VELICEA, Laura VISU-PETRA

“…Of the 248 articles initially found, only 12 were included in the scoping review after eligibility screening. …”
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What does a migraine aura look like?—A systematic review by Ľubica Joppeková, Maria João Pinto, Mariana Dias da Costa, Richard Boček, Gabriele Berman, Yones Salim, Dinara Akhtanova, Aizhana Abzalbekova, Antoinette MaassenVanDenBrink, Christian Lampl, European Headache Federation School of Advanced Sciences (EHF-SAS)

“…Additional studies, including various neurophysiological techniques (such as EEG, VEP, or TMS), are needed to potentially identify specific patterns within MA that would help better characterise clinical and electrophysiological phenotypes. …”
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Extreme UV sensitivity of native Metarhizium spp. as potential biocontrol agent for False Codling Moth (Thaumatotibia leucotreta Meyrick) on chili pepper in Ghana by Patricia Akua Sitsofe Nyahe, Vincent Yao Eziah, Laith Khalil Tawfeeq Al-Ani, Monica Akumyoungta, Candice Anne Coombes, Drauzio Eduardo Naretto Rangel, Alene Alder-Rangel, Dalia Sukmawati, Owusu Fordjour Aidoo, Mavis Agyeiwaa Acheampong

“…Consequently, microbial biopesticides are urgently needed to complement current nonchemical control options for key pests of chili pepper, particularly the phytosanitary insect, False Codling Moth (FCM). …”
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Accessible viral metagenomics for public health and clinical domains with Jovian by Dennis Schmitz, Florian Zwagemaker, Sam Nooij, Thierry K. S. Janssens, Jeroen Cremer, Robert Verhagen, Harry Vennema, Annelies Kroneman, Marion P. G. Koopmans, Jeroen F. J. Laros, Miranda de Graaf

“…Abstract The integration of next-generation sequencing into clinical diagnostics and surveillance initiatives is impeded by the lack of data analysis pipelines that align with privacy legislation and laboratory certification protocols. …”
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Establishment of M2 macrophage-related prognostic signature in pancreatic ductal adenocarcinoma by Hui Chen, Jingyang Yin, Xianxing Wang, Renpei Xia, Fanbo Qin, Zhuo Li, Jiali Yang, Changjiang Liu, Shixiang Guo, Huaizhi Wang

“…Potential intercellular communication between M2, PDAC malignant cells, and fibroblasts was initially observed at the level of computer analysis. …”
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Treatment of wrist stiffness through posture orthosis and active exercise: A case report by Paolo Boccolari, Mario Lando, Lucia Zingarello, Leonardo Monzani Vecchi, Roberto Tedeschi, Danilo Donati

“…A more extensive study is necessary to evaluate the conservative treatment strategy's validity for such fractures in high-demand patients, considering the biomechanical complexity of the injury and the patient's professional needs.…”
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Impact of clean energy use on the health of rural residents in China: The mediating role of leisure activities and household cleanliness by Wenmei Liao, Chao Chen, Xunpeng Shi, Feng Ye

“…Against the backdrop of global sustainable development goals and Healthy China Initiative, investigating the health impacts of clean energy adoption in rural areas is critical for improving rural well-being and advancing sustainable social development. …”
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Evaluation of the Intensive Acute Flaccid Paralysis Surveillance System in Ghana: Post the Switch from tOPV to bOPV by Evangeline Obodai, Jessica Dufie Boakye, Nana Afia Asante Ntim, Gayheart Deladem Agbotse, Comfort Nuamah Antwi, Ewurabena Oduma Duker, Sharon Ansong Bimpong, Deborah Odame, Patience Lartekai Adams, Josephine Nayan, Jude Yayra Mensah, Angelina Evelyn Dickson, Keren Attiku, Isaac Baffoe-Nyarko, Dennis Laryea, John Kofi Odoom

“…The Global Polio Eradication Initiative was adopted by Ghana in 1996, and through robust AFP surveillance was able to interrupt the circulation of wild poliovirus in 2008. …”
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Regional cerebral blood flow in a patient with restless legs syndrome exhibiting pramipexole‐induced hypersexuality by Toshiki Obata, Ryota Kobayashi, Toshinori Shirata, Keisuke Noto, Yasuhiro Sugai, Gaku Aboshi, Masafumi Kanoto, Akihito Suzuki

“…Case Presentation A 60‐year‐old man with RLS developed hypersexuality after initiating pramipexole at 0.5 mg/day. He exhibited inappropriate sexual behaviors toward hospital staff. …”
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A new dawn: Vitalising translational oncology research in Africa with the help of advanced cell culture models by Stefanie Klima, Tracey Hurrell, Mubeen Goolam, Chrisna Gouws, Anna-Mart Engelbrecht, Mandeep Kaur, Iman van den Bout

“…This framework presents an opportunity for SSAC and LMIC to base their healthcare research on locally relevant models to ensure that developed health care initiatives and interventions are best suited for the populations they serve and thus represent a reset in global health care research at large.…”
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