Time to vasopressor initiation and organ failure progression in early septic shock by Lauren Page Black, Michael A. Puskarich, Carmen Smotherman, Taylor Miller, Rosemarie Fernandez, Faheem W. Guirgis

“…Abstract Objective Research evaluating the relationship between vasopressor initiation timing and clinical outcomes is limited and conflicting. …”
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Ending PJ paralysis for hospitalised patients: a quality improvement initiative by Frances Carr, Pamela Mathura, Jennifer Symon

“…Introduction PJ paralysis refers to the negative effects experienced by hospitalised patients who remain inactive and dressed in hospital clothing, and is a serious problem, affecting one-third of hospitalised older adults. This study evaluated the impact of a multicomponent hospital-based intervention to get patients out of bed, dressed in non-hospital attire, and moving around/mobilised.Methods A 3-month quality improvement initiative was conducted at one hospital unit in Western Canada, which aimed for 50% of all patients to be dressed in their own clothing by midday, sitting up in a chair for all meals and mobilising to activities. …”
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Echocardiographic Changes in Patients with End-Stage Renal Disease at Initiation of Dialysis by Shabana Nazneen, Muzamil Latief, Manjusha Yadla

“…Introduction: Echocardiography is a simple and established method of evaluating cardiac functions, assessing left ventricle geometry, and systolic and diastolic functions. …”
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Development and initial validation of the Interaction Anxiety in Group Work (IAGWS) Scale by Larry J. Xethakis, Michael Rupp, Brendan R. B. Plummer, Toshikazu Kawagoe

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Radiologically isolated syndrome: 5-year risk for an initial clinical event. by Darin T Okuda, Aksel Siva, Orhun Kantarci, Matilde Inglese, Ilana Katz, Melih Tutuncu, B Mark Keegan, Stacy Donlon, Le H Hua, Angela Vidal-Jordana, Xavier Montalban, Alex Rovira, Mar Tintoré, Maria Pia Amato, Bruno Brochet, Jérôme de Seze, David Brassat, Patrick Vermersch, Nicola De Stefano, Maria Pia Sormani, Daniel Pelletier, Christine Lebrun, Radiologically Isolated Syndrome Consortium (RISC), Club Francophone de la Sclérose en Plaques (CFSEP)

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Determinants of breastfeeding initiation in thailand: multiple indicator cluster survey analysis by Salila Cetthakrikul, Chompoonut Topothai, Nisachol Cetthakrikul

“…Logistic regression analysis was used to evaluate the association between geographic, socioeconomic, and maternal factors with early initiation of breastfeeding. …”
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The Assessment of Morphological and Functional Changes in the Detection of the Initial Stage of Primary Glaucoma by N. I. Kurysheva, L. V. Lepeshkina

“…Progressive thinning of the retinal nerve fiber layer (RNFL) and its ganglion cell complex (GCC) were evaluated using SD-OCT. If RNFL and/or GCC had a trend of significant (p < 0.05) thinning, the eye was classified as having the SD-OCT progression. …”
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The microbiota vault initiative: safeguarding Earth’s microbial heritage for future generations by Maria G. Dominguez-Bello, Dominik Steiger, Manuel Fankhauser, Adrian Egli, Pascale Vonaesch, Nicholas A. Bokulich, Anton Lavrinienko, Christian Hoffmann, Petra Zimmermann, Abdifatah Muhummed, Somphou Sayasone, Amma Larbi, Segla Wilfrid Padonou, Jakob Zinsstag, Rea Tschopp, Chalat Santivarangkna, Diana Albertos Torres, Yuen Yi Li, Vanni Benvenga, Youzheng Teo, Marcel Houngbédji, Alex Kwarteng, Rob Knight, Jack A. Gilbert, Martin J. Blaser

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The Eating Disorders Genetics Initiative 2 (EDGI2): study protocol by Natasha Berthold, Casey M. MacDermod, Laura M. Thornton, Richard Parker, Shantal Anid Cortés Morales, Liv Hog, Hannah L. Kennedy, Jerry Guintivano, Patrick F. Sullivan, James J. Crowley, Jessica S. Johnson, Andreas Birgegård, Bengt T. Fundín, Emma Frans, Jiayi Xu, Michaela Pettie “Ngāti Pūkenga”, Allison L. Miller, Mariana Valdez Aguilar, Sarah Barakat, Mohamed Abdulkadir, Jennifer P. White, Janne T. Larsen, Elsie Trujillo, Bertha Winterman, Ruyue Zhang, Rachel Lawson, Stephen Wonderlich, Joseph Wonderlich, Lauren M. Schaefer, Philip S. Mehler, Judy Oakes, Marina Foster, Jennifer Gaudiani, Eva Trujillo Chi Vacuán, Emilio J. Compte, Liselotte V. Petersen, Zeynep Yilmaz, Nadia Micali, Jennifer Jordan, Martin A. Kennedy, Sarah Maguire, Laura M. Huckins, Yi Lu, Lisa Dinkler, Nicholas G. Martin, Cynthia M. Bulik

“…Abstract Background The Eating Disorders Genetics Initiative 2 (EDGI2) is designed to explore the role of genes and environment in anorexia nervosa, bulimia nervosa, binge-eating disorder, and avoidant/restrictive food intake disorder (ARFID) with a focus on broad population representation and severe and/or longstanding illness. …”
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Obinutuzumab as Initial or Second-Line Therapy in Patients With Primary Membranous Nephropathy by Xiaole Su, Binxin Wu, Xuan Tie, Xiaojiao Guo, Rongrong Feng, Xi Qiao, Lihua Wang

“…The potential of Obinutuzumab was highlighted as an initial therapy for primary MN.…”
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Evaluation Roots: An International Perspective by Fred Carden, Marvin C. Alkin

“…Findings: Two important distinctions emerged in evaluation roots in LMICs. The first is that much evaluation fits effectively on the Theory Tree as it is presented, with perhaps some nuance, but we see a collective rather than individual origin of the evaluation theory writings we have uncovered. …”
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Training and performance assessment of NPP operators on comprehensive simulators by О. Стенін, В. Пасько, О. Лісовиченко, С. Стенін, В. Солдатов

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Application of the multiphase optimisation strategy to develop, optimise and evaluate the effectiveness of a multicomponent initiative package to increase 2-to-5-year-old children’s vegetable intake in long day care centres: a study protocol by Rebecca K Golley, Shabnam Kashef, Dorota Zarnowiecki, Jennifer C Arguelles, David N Cox, Astrid AM Poelman, Maeva O Cochet-Broch

“…Repeated measures ANOVA with interaction effects (optimisation phase) and linear mixed modelling (evaluation phase) will test effects of the initiatives on vegetable intake.Ethics and dissemination This study has received ethics approval from the Flinders University Research Ethics Committee (Project No: 1873) for the optimisation phase. …”
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Protocol for a cluster randomised trial evaluating a multifaceted intervention starting preconceptionally—Early Interventions to Support Trajectories for Healthy Life in India (EINSTEIN): a Healthy Life Trajectories Initiative (HeLTI) Study by Mary Barker, Janis Baird, K S Joseph, Cindy-Lee Dennis, Zulfiqar A Bhutta, Prakesh S Shah, Saumyadipta Pyne, Nalini Singhal, Murali Krishna, Prabhat Jha, Harshpal Singh Sachdev, Kalyanaraman Kumaran, Caroline H D Fall, Stephanie Atkinson, Stephen Lye, Stephen G Matthews, Daniel Sellen, Ghattu V Krishnaveni, Kumar Gavali Suryanarayana, Manohar Prabhu Prasad, Antonisamy Belavendra, Ramaswamy Balasubramaniam, Robert H J Bandsma, Giriraj Ratan Chandak, Elena M Comelli, Sandra T Davidge, Geoffrey L Hammond, Sadhana R Joshi, Kang Lee, Patrick McGowan, Pablo Nepomnaschy, Vivek Padvetnaya, Sirazul Ameen Sahariah, Jacquetta Trasler, Chittaranjan S Yajnik, Marie-Claude Martin, Nusrat Husain

“…Introduction The Healthy Life Trajectories Initiative is an international consortium comprising four harmonised but independently powered trials to evaluate whether an integrated intervention starting preconceptionally will reduce non-communicable disease risk in their children. …”
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Efficacy, safety, and economic evaluation of Ojeok-san plus Saengmaek-san for gastroesophageal reflux-induced chronic cough: Protocol for a randomized, double-blind, placebo-controlled, parallel, multicenter, investigator-initiated clinical trial. by Yee Ran Lyu, O-Jin Kwon, Ae-Ran Kim, Min Ji Kim, Yoon Jae Lee, Kwan-Il Kim, Jae-Woo Park, Seok-Jae Ko, Yang-Chun Park, Jun-Yong Choi, Tae-Yong Park, Jun-Hwan Lee, Beom-Joon Lee

“…All participants will be instructed to receive OJS plus SMS or a placebo for 6 weeks and visit hospitals every 2 weeks until week 8 to evaluate their efficacy or safety outcomes. For efficacy outcomes, the cough diary score, cough VAS, Leicester Cough Questionnaire, Gastroesophageal Reflux Disease Questionnaire, Hull Airway Reflux Questionnaire, and 5-level EuroQol 5-dimensional Questionnaire will be evaluated to observe symptoms of cough and GERD, as well as the quality of life in patients with GERC. …”
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F-18 fluorocholine positron emission tomography–computed tomography in initial staging and recurrence evaluation of prostate carcinoma: A prospective comparative study with diffusion-weighted magnetic resonance imaging and whole-body skeletal scintigraphy by Rakhee Vatsa, Rohit Kumar, Jaya Shukla, Nivedita Rana, Shelvin Vadi, Anupam Lal, Shrawan Singh, Bhagwant Mittal

“…The present prospective study evaluates and compares the role of F-18 FCH positron emission tomography–computed tomography (PET-CT) with locoregional MRI and whole-body bone scintigraphy in PCa patients for initial staging and recurrence evaluation. …”
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The Interplay of Tangibles and Intangibles in Evaluation by Mita Marra

“…Rist, which began in 1997 and has evolved through decades of shared work in evaluation. Grounded in international development and governance, our collaboration has explored both tangible and intangible dimensions of evaluation to enhance institutional learning and policymaking. …”
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Initial Feasibility of a Woman-Focused Intervention for Pregnant African-American Women by Hendrée E. Jones, Nancy D. Berkman, Tracy L. Kline, Rachel Middlesteadt Ellerson, Felicia A. Browne, Winona Poulton, Wendee M. Wechsberg

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MRI-Driven Longitudinal Studies of Hippocampal Alterations During the Initial Cognitive Decline by Qunxi Dong, Yuhang Sheng, Junru Zhu, Honghong Liu, Zhigang Li, Jingyu Liu, Yalin Wang, Bin Hu

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Assessment of the intensive phase 'Shakti Divas' initiative to combatting anemia in Rajasthan, India. by Nitin Kumar Joshi, Pankaj Bhardwaj, Akhil Dhanesh Goel, Tanisha Garg, Yogesh Kumar Jain, Manoj Kumar Gupta, Prem Singh, Jitendra Kumar Soni

“…This included surveys in Anganwadi centers and government schools, and home visits for out-of-school children, pregnant and lactating women not coming to Anganwadi centres. For outcome evaluation, IFA coverage data was obtained from government web portals one-month before and six-months after the launch of initiative. 38 in-depth interviews were conducted to assess the challenges and barriers.…”
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