Promoter demethylation of cerebellin 2 by ten-eleven translocation 3 contributes to peripheral sensitization in trigeminal neuropathic pain of mice by Xin-Ying Guan, Bao-Tong Yuan, Meng-Na Li, Tian Wang, Lin-Peng Zhu, Si-Yuan Song, Lu-Lu Ji, Yong-Jing Gao, Ling-Jie Ma

“…Quantitative real-time PCR (qRT-PCR), Western blotting and enzyme-linked immunosorbent assay (ELISA) were performed to evaluate the expression of CBLN2. Immunofluorescence was used to determine CBLN2’s cellular localization. …”
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Design and Application of GISC Beijing Global Cache by Gu Wenjing, Guo Ping, Zhang Laien, Xue Lei, Han Xinqiang, Gao Feng, He Wenchun, Wang Huaile, Wang Peng, Wang Bo

“…In response, World Meteorological Organization (WMO) has initiated the crucial process of replacing WIS/GTS with the advanced WMO Information System 2.0 (WIS2.0) in 2023. …”
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Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling by Bisha Ding, Jie Li, Jia-Lin Yan, Chun-Yan Jiang, Ling-Bo Qian, Jie Pan

“…ULBP2-NKG2D ligation initiates NK cell activation and subsequent targeted elimination of cancer cells. …”
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Rotavirus epidemiology of children in Bursa, Turkey: a multi-centered hospital-based descriptive study by Mustafa Hacimustafaoğlu, Solmaz Celebi, Mehmet Ağin, Güven Ozkaya

“… In this multi-centered study, we aimed to evaluate the distributional incidence of rotavirus acute gastroenteritis (RVAGE) according to age groups and epidemiological features of hospitalized and outpatient cases in the city center of Bursa, Turkey. …”
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Heterogeneity and efficacy of immunotherapy in multiple cancer: insights from a meta-analysis by Weidong Wu, Bin Liu, Qing Zhang, Xiaojuan Zhang, Pengya Feng, Yongliang Jia, Xia Xue

“…A total of 649 studies were initially identified through database searching. After removing duplicates and non-clinical cancer studies, 32 eligible studies were included in this work. …”
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Effectiveness of Interventions to Improve Digital Health Literacy in Forced Migrant Populations: Mixed Methods Systematic Review by Achille Roghemrazangba Yameogo, Carole Délétroz, Maxime Sasseville, Samira Amil, Sié Mathieu Aymar Romaric Da, James Plaisimond, Frédéric Bergeron, Sofia Tadlaoui, Patrick Bodenmann, Marie-Pierre Gagnon

“…However, DHL is often limited among forced migrant populations, who usually lack the skills to understand and evaluate health information or to access and use digital health resources appropriately. …”
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Innovative Mobile App (CPD By the Minute) for Continuing Professional Development in Medicine: Multimethods Study by Peter Slinger, Maram Omar, Sarah Younus, Rebecca Charow, Michael Baxter, Craig Campbell, Meredith Giuliani, Jesse Goldmacher, Tharshini Jeyakumar, Inaara Karsan, Janet Papadakos, Tina Papadakos, Alexandra Jane Rotstein, May-Sann Yee, Asad Siddiqui, Marcos Silva Restrepo, Melody Zhang, David Wiljer

“…Future research efforts should prioritize evaluating the app’s long-term sustainability and its impact on physicians’ practice, as well as exploring alternative approaches (such as artificial intelligence–based tools) for generating questions.…”
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Application of machine learning algorithm for prediction of abortion among reproductive age women in Ethiopia by Angwach Abrham Asnake, Alemayehu Kasu Gebrehana, Hiwot Altaye Asebe, Beminate Lemma Seifu, Bezawit Melak Fente, Meklit Melaku Bezie, Mamaru Melkam, Sintayehu Simie Tsega, Yohannes Mekuria Negussie, Zufan Alamrie Asmare

“…The dataset was randomly split into training and testing sets, with 80% allocated for training and 20% for testing. To evaluate the performance of each predictive model, we used a range of metrics such as accuracy, precision, recall, F1-score, and area under the curve (AUC). …”
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Co-Designing a Consumer-Focused Digital Reporting Health Platform to Improve Adverse Medicine Event Reporting: Protocol for a Multimethod Research Project (the ReMedi Project) by Eyob Alemayehu Gebreyohannes, Christopher Thornton, Myra Thiessen, Sieta T de Vries, Andre Q Andrade, Lisa Kalisch Ellett, Oliver Frank, Phaik Yeong Cheah, Kim-Kwang Raymond Choo, Tracey Lea Laba, Elizabeth E Roughead, Indae Hwang, Geraldine Moses, Renly Lim

“…Process and outcome evaluations will be conducted to assess the implementation process and to determine whether the new platform has increased AME detection and reporting. …”
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The Role of Tumor Necrosis Factor and ITS Soluble Receptors in Myelosuppression Developing in B-Cell Chronic Lymphocytic Leukemia by Barilka V., Matlan V., Prymak S., Vygovska O., Shalay O.

“…So, determination of TNF and its soluble receptors may be used to predict the development of anemia as well as to initiate the treatment in B-CLL pts.…”
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Impact of positive end-expiratory pressure and recruitment maneuver on healthy lungs in dogs assessed by functional and anatomical monitoring methods by Martina Mosing, Martina Mosing, Andreas D. Waldmann, Thom C. Gent, Giselle Hosgood, Nadja S. Sieber-Ruckstuhl, Matthias Dennler, Peter Herrmann, Karin Unger

“…Thereafter, either (1) ZEEP was continued, (2) PEEP initiated or (3) an RM was performed followed by PEEP. …”
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‘Machine Learning’ multiclassification for stage diagnosis of Alzheimer’s disease utilizing augmented blood gene expression and feature fusion by Manash Sarma, Subarna Chatterjee

“…This investigation utilizes blood gene expression datasets obtained from participants in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the National Center for Biotechnology Information (NCBI). …”
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Electromiografía de superficie durante diferentes tipos de sentadillas. Una revisión narrativa (Surface electromyography during different types of squats. A narrative review) by Alejandro Arango Sarmiento, Diego Alejandro Calderón López, María Isabel Torres Cadavid, Juan Camilo Martínez Montoya, Andrés Ocampo García

“…These articles focused on analyzing squat execution and its variations using electromyography. Initially, a total of 340 articles related to the topic were found. …”
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Genetic surveillance shows spread of ACT resistance during period of malaria decline in Vietnam (2018-2020) by Johanna Helena Kattenberg, Mathijs Mutsaers, Van Hong Nguyen, Thi Hong Ngoc Nguyen, Arlette Umugwaneza, Maria Lara-Escandell, Xuan Xa Nguyen, Thi Huong Binh Nguyen, Anna Rosanas-Urgell

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Automated Video Assistant Referee in Lead Climbing by Eliane Künzler, David Roder, Urs Stöcker, Peter Wolf

“…Methods Our video footage was filmed by the Swiss Alpine Club for judging at the European Climbing Championships 2024 in Villar and at the Swiss Championships 2024 in Lenzburg. Initially, twenty videos (30 seconds each including the fall from the wall towards the end) were extracted. …”
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Randomised, double-blind, phase III study comparing the infliximab biosimilar, PF-06438179/GP1111, with reference infliximab: efficacy, safety and immunogenicity from week 30 to we... by Goran Babic, Hideto Kameda, Rieke Alten, Bogdan Batko, Tomas Hala, Sebastiao C Radominski, Vira Tseluyko, Carol Cronenberger, Sarah Hackley, Muhammad Rehman, Oliver von Richter, Min Zhang, Stanley Cohen

“…Efficacy, safety, immunogenicity and pharmacokinetics were evaluated.Results During TP2, patients in all three treatment groups continued to maintain comparable treatment response. …”
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On the Treatment of Acute Poisoning With Paracetamol by A. Yu. Simonova, M. M. Potskhveriya, M. V. Belova, K. K. Ilyashenko, V. V. Kulabuhov, N. Y. Stolbova, A. E. Klyuev

“…The use of ACC according to a 21-hour protocol in patients with initially elevated ALT and AST levels of more than 50 U/L (n = 4) (25%) led to a rapid positive dynamics of laboratory and clinical parameters. …”
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A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain by Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

“…Recognizing that the management program for patients with lumbar discogenic pain can be highly personalized, the treatment options recommended by this algorithm should be considered general guidance.Conclusion: The proposed algorithm offers an easy-to-use clinical tool for identifying, evaluating and treating patients with lumbar discogenic pain. …”
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Business model development for installation of rubber floor mats to support productivity in dairy farming by Suteera Chanthes, Weerasak Sawangloke, Rujira Luangsakdapich, Adisak Pattiya, Yottha Srithep

“…It could also guide the agricultural policymakers to benchmark and evaluate their policy targeting innovative knowledge-based business development for rubber extension.…”
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PREDİCTİON OF THE RİSK OF LEUKEMİA DEVELOPMENT İN AGED HEALTHY POPULATİON: IMPLEMENTATİON İN THE PUBLİC HEALTH SYSTEM by Francesco Frassoni, Roberto Tedone, Emanuela Marcenaro, Giorgio Piastra, Davide Guerr

“…The experimentation is carried out in the territory of the Regional-Health-Service (ASL5) of Eastern Liguria (Italy), with the aim of verifying and evaluating both the organizational model and the technological infrastructure to support it, with the ambition of initially sequencing the DNA with a panel of about 90 genes. …”
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