Political Order and Nomadic Life in Iran: From the Afsharid Period to the End of the Qajar Dynasty by Shahram Gholami, Siavash Gholipour

“…This article sought to critically evaluate the role of environmental adaptability as a cause for the spread of nomadism, aligning more closely with the latter perspective. …”
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Impact of proactive malaria community case management (proCCM) on parasite prevalence and incidence from 2021 to 2023: a randomised controlled trial in Chadiza District, Eastern Pr... by Adam Bennett, Busiku Hamainza, Marie-Reine I Rutagwera, Ellen L Ferriss, Bupe M Kabamba, Travis Porter, Chabu C Kangale, Sarah Gallalee, Melody Simataa, John M Miller, Caroline Phiri-Chibawe, Maximillian Musunse, Patrick Nyendwa, Viennah Kapenda, Paul Psychas, Julie R Gutman, Moonga Hawela, Ignatius Banda, Sampa Chitambala-Otiono, Julie I Thwing

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Exploring Candesartan, an angiotensin II receptor antagonist, as a novel inhibitor of NLRP3 inflammasome: alleviating inflammation in Neisseria gonorrhoeae infection by Wen-Yu Lin, Jin-Lian Tsui, Hsiao-Wen Chiu, Wei-Ting Wong, Chun‑Hsien Wu, Hsien-Ta Hsu, Chen-Lung Ho, Shan-Pei Yeh, Yerra Koteswara Rao, Ann Chen, Chien-Chun Wang, Chung-Hua Hsu, Oleg V. Chernikov, Kuo-Feng Hua, Lan-Hui Li

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Influences of work stressors and family support: the mediating role of job performance by Rajpreet Kaur

“…Community engagement and recognition initiatives, along with specialized training on work-family balance, can foster positive morale. …”
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TNFR2 blockade promotes antitumoral immune response in PDAC by targeting activated Treg and reducing T cell exhaustion by Eliane Piaggio, Allan Thiolat, Anais Debesset, Caroline Pilon, Benoît Laurent Salomon, José Laurent Cohen, Sylvain Baulande, Sylvain Meunier, Orianne Cuelenaere-Bonizec, Wilfrid Richer, Claire Houppe, Matteo Ponzo, Jeanne Magnan, Jonathan Caron, Pamela Caudana, Jimena Tosello Boari, Nhu Han To, Ilaria Cascone

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Assessment of Oral Poliovirus Vaccine Viability and Titer at Delivery Points in Kinshasa, the Democratic Republic of the Congo: Implications for Cold Chain Management by Gracia Kashitu-Mujinga, Anguy Makaka-Mutondo, Meris Matondo-Kuamfumu, Fabrice Mambu-Mbika, Junior Bulabula-Penge, Trésor Kabeya-Mampuela, Frida Nkawa, Grace Wanet-Tayele, Bibiche Nsunda-Makanzu, Pierre Nsele-Muntatu, Lusamba Kabamba, Antoine Nkuba-Ndaye, Aimé Mwana wa bene Cikomola, Elisabeth Mukamba-Musenga, Steve Ahuka-Mundeke

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Development and validation of a novel clinical risk score to predict hypoxaemia in children with pneumonia using the WHO PREPARE dataset by Shamim Qazi, Arjun Chandna, Norman Lufesi, Philippe Vanhems, Tim Colbourn, Charles Mwansambo, Eric D McCollum, Mathuram Santosham, Shally Awasthi, Archana Patel, Joseph L Mathew, Tor A Strand, Carina King, Rakesh Lodha, Shubhada Hooli, Mark I Neuman, Vanessa Rouzier, Ashish Bavdekar, Nitya Wadhwa, Donald M Thea, Rainer Tan, Emmanuel Addo-Yobo, Chris A Rees, Shinjini Bhatnagar, Shabir A Madhi, Kerry-Ann F O’Grady, Sudha Basnet, Patricia Hibberd, Valentina S Picot, Pagbajabyn Nymadawa, Marilla Lucero, Glaucia Paranhos-Baccalà, Juan M Lozano, Yasir Bin Nisar, Prakash M Jeena, Marta Nunes, Noel Chisaka, Ngoc Tuong Vy Nguyen, Monidarin Chou, Mala Rakoto-Andrianarivelo, Graciela Russomando, Mariam Sylla, Jianwei Wang, Satinder Aneja, Alexey W Clara, Fenella Beynon, Romina Libster, Jean William Pape, Clare L Cutland, Brad Gessner, William B MaLeod, Syed Mohammad Akram uz Zaman, Gillian Levine

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Understanding mental health among university students in Kenya: what role do family support and age play? by Bylhah Mugotitsa, Bylhah Mugotitsa, Reinpeter Momanyi, Joseph Kuria, David Amadi, Jacob Masai, Eric Angula, Benjamin Tsofa, Benjamin Tsofa, Jay Greenfield, Jim Todd, Agnes Kiragga

“…Additionally, integrating family engagement initiatives to strengthen family support structures can serve as a protective factor against mental health challenges. …”
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Trends in the global, national, and regional burden of breast cancer among adolescents and young adults from 1990 to 2021: Analyses of the 2021 global burden of disease study by Da Qian, Weimin Hong, Shujin Li, Haotian Liu, Chaoqi He, Xiaozhen Liu, Guoxin Huang, Xuli Meng, Yiwen Zheng

“…Background: This study was devised to evaluate the burden of breast cancer (BC) among adolescents and young adults (AYAs) between 1990 and 2021. …”
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Barriers and enablers of HPV vaccination among caregivers of school-age girls in resource-limited regions of Western Sichuan, China: a mixed-methods study by Qiwen Zhang, Lu Zhang, Zubo Huang, Yue Zeng, Yueshan Wang, Jieru Peng, Yan Kou, Wei Huang, Gang Zhu, Wencheng Long, Yao Dong, Chunxia Yang

“…The provincial government has initiated vaccination programs, with a particular focus on impoverished areas such as the Ganzi, Aba, and Liangshan prefectures, where both the HPV disease burden is elevated and vaccination uptake remains suboptimal. …”
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Optimizing Lucerne Productivity and Resource Efficiency in China’s Yellow River Irrigated Region: Synergistic Effects of Ridge-Film Mulching and Controlled-Release Nitrogen Fertili... by Minhua Yin, Yuanbo Jiang, Yi Ling, Yanlin Ma, Guangping Qi, Yanxia Kang, Yayu Wang, Qiang Lu, Yujie Shang, Xiangrong Fan, Gangqiang Han, Boda Li, Jiapeng Zhu, Jinxi Chen, Haiyan Li

“…With increasing N application rates, WUE, IWUE, and ANUE initially rose and then declined, peaking under N2, whereas PFPN showed a decreasing trend and reached its maximum under N1. …”
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Improved robustness for deep learning-based segmentation of multi-center myocardial perfusion cardiovascular MRI datasets using data-adaptive uncertainty–guided space-time analysis... by Dilek M. Yalcinkaya, MS, Khalid Youssef, PhD, Bobak Heydari, MD, Janet Wei, MD, C. Noel Bairey Merz, MD, Robert Judd, PhD, Rohan Dharmakumar, PhD, Orlando P. Simonetti, PhD, Jonathan W. Weinsaft, MD, Subha V. Raman, MD, Behzad Sharif, PhD

“…Methods: Datasets from three medical centers acquired at 3T (n = 150 subjects; 21,150 first-pass images) were included: an internal dataset (inD; n = 95) and two external datasets (exDs; n = 55) used for evaluating the robustness of the trained deep neural network (DNN) models against differences in pulse sequence (exD-1) and scanner vendor (exD-2). …”
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A validated heart-specific model for splice-disrupting variants in childhood heart disease by Robert Lesurf, Jeroen Breckpot, Jade Bouwmeester, Nour Hanafi, Anjali Jain, Yijing Liang, Tanya Papaz, Jane Lougheed, Tapas Mondal, Mahmoud Alsalehi, Luis Altamirano-Diaz, Erwin Oechslin, Enrique Audain, Gregor Dombrowsky, Alex V. Postma, Odilia I. Woudstra, Berto J. Bouma, Marc-Phillip Hitz, Connie R. Bezzina, Gillian M. Blue, David S. Winlaw, Seema Mital

“…Results Of 8583 rare DNA splice-disrupting variants initially identified using SpliceAI, 100 were associated with altered splice junctions in the corresponding patient myocardium affecting 95 genes. …”
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Sarcolemma resilience and skeletal muscle health require O-mannosylation of dystroglycan by Jeffrey M. Hord, Sarah Burns, Tobias Willer, Matthew M. Goddeeris, David Venzke, Kevin P. Campbell

“…O-mannose glycan biosynthesis is initiated by the protein O-mannosyltransferase 1 (POMT1) and POMT2 enzyme complex and leads to three subtypes of glycans called core M1, M2, and M3. …”
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Immune checkpoint inhibitors in patients with pre-existing psoriasis: safety and efficacy by Andrew Haydon, Jessica C Hassel, Jeffrey A Sosman, Sunandana Chandra, Ryan Sullivan, Mario E Lacouture, Matteo Carlino, Meghan J Mooradian, Alexander Menzies, Douglas B Johnson, Fei Ye, Prachi Bhave, Steven T Chen, Georgina Long, Allison Betof Warner, Briana Rose Halle, Farzana Y Zaman, Anna K Dewan, Rebecca Irlmeier, Paras Mehta, Nicholas R Kurtansky, Jacob S Choi, Tracey S Otto, Florentia Dimitriou, Veronica M Rotemberg

“…Forty-one patients (54%) had received any prior therapy for psoriasis although only two (3%) were on systemic immunosuppression at ICI initiation. With ICI treatment, 43 patients (57%) experienced a psoriasis flare of cutaneous and/or extracutaneous disease after a median of 44 days of receiving ICI. …”
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A Hierarchical Machine Learning-Based Strategy for Mapping Grassland in Manitoba’s Diverse Ecoregions by Mirmajid Mousavi, James Kobina Mensah Biney, Barbara Kishchuk, Ali Youssef, Marcos R. C. Cordeiro, Glenn Friesen, Douglas Cattani, Mustapha Namous, Nasem Badreldin

“…In step 3, after filtering out non-grassland pixels, the performance of RF, SVM, and GTB classifiers was evaluated with combined S1 and S2 data to distinguish different grassland types. …”
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Additional expression of T-cell engager in clinically tested oncolytic adeno-immunotherapy redirects tumor-infiltrated, irrelevant T cells against cancer cells to enhance antitumor... by Bora Lim, Caroline Porter, Mae Woods, Masataka Suzuki, Daisuke Morita, Amanda Rosewell Shaw, Greyson Biegert, Spyridoula Vasileiou

“…Since CAdVEC treatment initially amplified Ad-specific T cells in patients, we re-direct these virus-specific T cells to target tumor cells by additionally expressing CD44v6.BiTE from CAdTetra. …”
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Combined immunotherapy with dendritic cells and cytokine-induced killer cells for solid tumors: a systematic review and meta-analysis of randomized controlled trials by Wendi Jiang, Zhongda Wang, Qinghuizi Luo, Zhe Dai, Jialong Zhu, Xiaoyue Tao, Yiyang Xie, Yuanyang Du, Longwei Jiang, Xiaoyuan Chu, Gongbo Fu, Zengjie Lei

“…Results A total of 1013 records were initially retrieved, and after a thorough screening process, 13 randomized controlled trials (RCTs) were included in the meta-analysis. …”
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Decomposing socioeconomic and educational inequalities in infant mortality in Sub-Saharan Africa: DHS insights linked to countdown to 2030 and agenda 2063 by Rahel Mulatie Anteneh, Zekaryas Ewnetu Gashu, Lemlem Daniel Baffa, Desalegn Anmut Bitew, Chalachew Yenew, Kaleb Assegid Demissie, Bewuketu Terefe, Melak Jejaw, Alebachew Ferede Zegeye, Misganaw Guadie Tiruneh, Tadesse Tarik Tamir, Tadele Biresaw Belachew, Wubshet Debebe Negash, Elsa Awoke Fentie, Desale Bihonegn Asmamaw

“…Data cleaning was performed using Microsoft Excel, and statistical analyses were conducted with STATA Version 17 software. To evaluate wealth-related inequalities in infant mortality, we employed the concentration index and curve, alongside Wag staff decomposition analysis. …”
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Molecular and cellular aspects of the impact of secondary metabolites from common barberry and hybrid goat’s rue on the HeLa cell line by E. Yu. Zlatnik, Ya. S. Enin, O. N. Burov, E. S. Bondarenko, A. B. Sagakyants, D. S. Kutilin, Yu. V. Dzigunova, O. G. Ishonina, E. V. Shalashnaya, N. D. Ushakova

“….), as well as to conduct a model experiment and molecular genetic study to evaluate their cytotoxic effect in vitro on the HeLa cell line.Materials and methods. …”
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