Dose-dependent dual effects of HDAC inhibitors on glial inflammatory response by Samantha Mancino, Mariaserena Boraso, Andrea Galmozzi, Melania Maria Serafini, Emma De Fabiani, Maurizio Crestani, Barbara Viviani

“…Abstract Neuroinflammation is defined as a process that includes cellular responses designed to protect the central nervous system from external influences, and it initiates in cases of extreme deviations from homeostasis. …”
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Biocompatibility and Effectiveness of Amphotericin B-Loaded Metal-Organic Structures (AmB-ZIF-8) as Dermal Drug Transporters in Experimental Cutaneous Leishmaniasis by Carreño H, Osorio J, Mejía-Ospino E, Escobar P

“…Hydrogels were prepared and evaluated for toxicity and efficacy in CL-BALB/c mice.Results: AmB@ZIF-8 exhibited a 59.6% loading capacity, 6.67% encapsulation efficiency, and 2% in vitro drug release (IVR). …”
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Exploring the role of breastfeeding, antibiotics, and indoor environments in preschool children atopic dermatitis through machine learning and hygiene hypothesis by Jinyang Wang, Haonan Shi, Xiaowei Wang, Enhong Dong, Jian Yao, Yonghan Li, Ye Yang, Tingting Wang

“…In this community-based case–control study with a 1:4 matching design, we evaluated the prevalence of AD in preschool-aged children. …”
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KATALIKYBĖ IR VISUOMENĖ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…Because of this they did not hurry to initiate the reforms. Irrespectively of this, the thoughts, expressed publicly by modernists, stimulated the heads of the Church to listen to them more attentively and respond to them. …”
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Using a Multilingual AI Care Agent to Reduce Disparities in Colorectal Cancer Screening for Higher Fecal Immunochemical Test Adoption Among Spanish-Speaking Patients: Retrospective... by Meenesh Bhimani, R Hal Baker, Markel Sanz Ausin, Gerald Meixiong, Rae Lasko, Mariska Raglow-Defranco, Alex Miller, Subhabrata Mukherjee, Saad Godil, Anderson Cook, Jonathan D Agnew, Ashish Atreja

“…MethodsThis retrospective analysis examined an AI-powered outreach initiative at WellSpan Health in Pennsylvania and Maryland during September 2024. …”
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KATALIKYBĖ IR VISUOMENĖ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…Because of this they did not hurry to initiate the reforms. Irrespectively of this, the thoughts, expressed publicly by modernists, stimulated the heads of the Church to listen to them more attentively and respond to them. …”
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Analysis of Blockchain-Technology by Danylo Dvorchuk, Iryna Shpinareva

“…The study explores the comparative advantages and limitations of different blockchain architectures and evaluates emerging optimization techniques such as hybrid consensus algorithms and artificial intelligence-based enhancements. …”
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Pulmonary Hypertension in Patients of Chronic Kidney Disease on Maintenance Hemodialysis: Study from a Tertiary Care Center in Central India by Trishala Chhabra, Naresh Pahwa, Shraddha Goswami, Riyaz Asad, Mohit Mahajan, Sharada Chandrashekhar Aher

“…This issue needs to be evaluated in a timely manner to avoid the risk of morbidity and mortality. …”
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The assessment of dupilumab in children with moderate-to-severe asthma and comorbid type 2 inflammatory diseases by Tingting Shi, Shuning Wu, Rongshan Chen, Yaping Xie, Genquan Yin, Chunhui He, Cuiping Liang, Gen Lu

“…Methods We evaluated the medical records of paediatric patients with moderate-to-severe asthma and comorbid type 2 inflammatory diseases, such as atopic dermatitis (AD) and allergic rhinitis (AR), receiving dupilumab treatment. …”
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Polymorphism of proinflammatory inerleukin genes in primary open-angle glaucoma by L. Yu. Barycheva, D. M. Kakulia, M. M. Minasyan, V. V. Kuznecova, N. A. Kozmova

“…The level of pro-inflammatory cytokines (TNFα and IL1β) in the lacrimal fluid of patients with POAG was evaluated by enzyme-linked immunosorbent assay (Vector-Best test system). …”
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The Gut Microbiota and the Nerve-Bone Axis: Insights from a Mendelian Randomization and Mediation Analysis by Qiao X, Lou Y, Chen H, Zhang H, Cao J, Feng X, Guo L, Pan Q

“…We used heart rate variability (HRV) to represent the activity of ANS in the MR analysis. Initially, we employed a two-sample MR approach to evaluate the causal impact of gut microbiota on BMD. …”
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THE TIME COURSE OF CHANGES IN B LYMPHOCYTE SUBPOPULATIONS IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS DURING THERAPY WITH BIOLOGICAL AGENTS by A. A. Mesnyankina, S. K. Solovyev, E. N. Aleksandrova, A. P. Aleksankin, E. V. Suponitskaya, A. V. Elonakov, E. A. Aseeva, E. L. Nasonov

“…A rapid recovery of the count of memory B cells and plasmablasts after a RTM cycle at 6 months after therapy initiation should be evaluated as a predictor of early exacerbation of SLE. …”
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Optimizing Genomic Selection Methods to Improve Prediction Accuracy of Sugarcane Single-Stalk Weight by Zihao Wang, Chengcai Xia, Yanjie Lu, Qi Liu, Meiling Zou, Fenggang Zan, Zhiqiang Xia

“…Initially, we compared the performance of five prediction approaches, including genomic best linear unbiased prediction (GBLUP), single-step genomic best linear unbiased prediction (SSBLUP), Bayes A, machine learning (ML), and deep learning (DL) approaches. …”
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Response to Sensor-Based Fertigation of Nagpur Mandarin (<i>Citrus reticulata</i> Blanco) in Vertisol of Central India by Deodas Meshram, Anoop Kumar Srivastava, Akshay Utkhede, Chetan Pangul, Vasileios Ziogas

“…., F₁, F₂, and F₃ (conventional fertilization practice), as sub-treatments, which were evaluated through a split-plot design over two harvesting seasons in 2021–2023. …”
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Perfusion index as a predictor of hypotension after spinal anesthesia in lower extremity orthopedic surgery: a prospective observational trial by Fatma Kavak Akelma, Milas Mafizer, Burak Nalbant

“…A saline infusion, limited to a maximum of 400 mL, was initiated prior to spinal anesthesia. All patients received 10-12.5 mg 0.5% hyperbaric bupivacaine for spinal anesthesia and the dermatomal distribution of the block was documented. …”
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BLEEDING RATE, FVIII UTILIZATION, CORTICOSTEROID USE, QUALITY OF LIFE AND SAFETY 4-YEARS AFTER GENE TRANSFER WITH VALOCTOCOGENE ROXAPARVOVEC IN A BRAZILIAN COHORT: RESULTS FROM GEN... by MC Ozelo, GGY Hayakawa, ANL Prezotti, MH Cerqueira, PR Villaça, C Lorenzatto, T Robinson

“…Objectives: To evaluate Annualized Bleeding Rate (ABR), Factor (F)VIII consumption, corticosteroid use, quality of life (QoL) and safety outcomes after 4-years post-gene transfer in the Brazilian cohort. …”
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Effectiveness of antipsychotic medication in patients with schizophrenia in a real world retrospective observational study in Ethiopia by Mulualem Kelebie, Getasew Kibralew, Gebresilassie Tadesse, Gidey Rtbey, Mekidem aderaw, Wondale Endeshaw, Mitiku Belachew, Mulu Muche, Diemesew Getnet, Setegn Fentahun

“…The effectiveness of prescribed antipsychotic medication was evaluated using the Clinical Global Impressions-Schizophrenia scale (CGI-SCH), inclusive of subscales for positive, negative, depressive, and cognitive symptoms. …”
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Neuropsychiatric and laboratory outcomes of hepatitis C treatment in an early-treated HIV cohort in Thailand by Ferron Ocampo, Carlo Sacdalan, Suteeraporn Pinyakorn, Misti Paudel, Tanyaporn Wansom, Nathornsorn Poltubtim, Somchai Sriplienchan, Nittaya Phanuphak, Robert Paul, Denise Hsu, Donn Colby, Lydie Trautmann, Serena Spudich, Phillip Chan, the RV254/SEARCH 010 Study Team

“…The latter included the Patient Health Questionnaire-9 (PHQ-9), Distress Thermometer (DT), and a 4-test cognitive battery that evaluated psychomotor speed, executive function, fine motor speed, and dexterity. …”
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A theory-based approach to explain the correlates of safe physical activity in pregnant and postpartum individuals by Asma T. AWAN, Kara N. RADZAK, Manoj SHARMA

“…Furthermore, outcomes from these activities can be evaluated using both quantitative and qualitative methodology. …”
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Medical Students&rsquo; Knowledge and Perceptions of Herbal Medicine in Saudi Arabia: Should Medical Schools Take Immediate Action? by Almech M, Alissa A, Baghdadi RA, Abujamai JZ, Hafiz W, Alwafi H, Shaikhomer M, Alshanberi AM, Alshareef MH, Alsanosi SM

“…To improve their understanding, it is essential to integrate comprehensive courses, organize workshops led by experts, promote research and clinical experiences, and establish patient education initiatives.Keywords: medical students’, herbal medicine, Saudi Arabia, medical schools…”
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