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20581
Impact of a mobile health intervention on health management among children with phenylketonuria based on a multi-theory model of the behavior change wheel theory and family health...
Published 2025-05-01“…The primary treatment for PKU is a strict low-Phe diet, which must be initiated in early life to achieve better outcomes. …”
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20582
Exploring symptoms perception and barriers to medication adherence among Thai Muslim patients with non-communicable diseases in a rural community in southern Thailand: a mixed-meth...
Published 2024-12-01“…Additionally, healthcare system-related factors, patient–doctor relationships and communication gaps in medication management during Ramadan were identified as factors influencing medication non-adherence.Conclusions To improve adherence, healthcare providers should prioritise fostering positive patient–provider relationships and promoting patient care through enhanced health literacy initiatives.…”
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20583
Pre-Hospital Point-of-Care Troponin: Is It Possible to Anticipate the Diagnosis? A Preliminary Report
Published 2025-01-01“…The secondary objective was to evaluate the feasibility of pre-hospital troponin testing. …”
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20584
Root architecture and carbon sequestration potential of fast-growing agroforestry tree species in semi-arid Central India
Published 2025-06-01“…This study, conducted from 2017 to 2019 in central India, evaluated the root structure and carbon sequestration potential of three tree species: Neolamarckia cadamba (Kadam), Leucaena leucocephala (Subabul), and Melia dubia (Malabar neem). …”
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20585
Composition of peripheral blood immune cell compartment in stage 5 chronic kidney disease is affected by smoking and other risk factors associated with systemic inflammatory respon...
Published 2025-08-01“…The impact of selected clinical factors on immune cell composition was initially evaluated using a robust multivariate method (PERMANOVA). …”
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20586
Spatial ratio of two fungal genotypes content of Naematelia aurantialba and Stereum hirsutum in nutritional growth substrate and fruiting bodies reveals their potential parasitic l...
Published 2025-08-01“…Nine species-specific fragments were selected, with four primer pairs validated after evaluating amplification efficiency and melting curves. …”
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20587
Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinemia: a re...
Published 2025-03-01“…Patients who experienced a rapid decline in TBIL levels during the early phase of treatment with PD-1 inhibitors and TKIs were observed to derive clinical benefits. Early initiation of aggressive interventions aimed at reducing TBIL levels is recommended to optimize treatment outcomes.…”
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20588
Platelet protease-activated receptor 4 genotype and response to aspirin in pregnancy
Published 2025-08-01“…PFA-100 was assessed at baseline, 2 to 4 weeks after aspirin initiation (follow-up 1), and 28 to 32 weeks’ gestation (follow-up 2). …”
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20589
The short-term effects of the implementation of the "Treat All" guidelines on ART service delivery costs in Namibia.
Published 2020-01-01“…The following study evaluated how costs changed after Namibia's introduction of TA in April 2017. …”
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20590
A multidimensional comparison of the benefit degrees for patients between ileostomy and colostomy
Published 2025-08-01“…The Cochrane bias risk assessment tool was used to evaluate the quality of the literatures. RevMan 5.3 was applied for statistical analysis, including heterogeneity test, calculation of p values and odds ratios (OR values), assessment of publication bias, and performance of sensitivity analysis.ResultsA total of 630 studies were initially retrieved, and finally 8 randomized controlled trials were included. …”
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20591
A humanized anti-Toll like receptor 4 antibody Fab fragment inhibits pro-inflammatory responses induced by lipopolysaccharide through TLR4 in vitro and in vivo
Published 2025-06-01“… Introduction: Toll like receptor 4 (TLR4) and its co-receptor MD-2 recognize bacterial lipopolysaccharide (LPS), initiating responses to infections caused by Gram-negative bacteria. …”
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20592
Agenda setting for health equity assessment through the lenses of social determinants of health using machine learning approach: a framework and preliminary pilot study
Published 2025-02-01“…Multiple ML models were developed and evaluated using SPSS Modeler software version 18.0. …”
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20593
Evidence-based general practice: a scoping review
Published 2025-05-01“…Our screening process involved evaluating titles, abstracts, and full texts to extract definitions and characteristics from all relevant records discussing EBGP. …”
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20594
LncRNA PVT1 promotes cuproptosis through transcriptional activation of FDX1 in colorectal cancer
Published 2025-09-01“…However, the molecular basis by which this process is initiated and sustained in tumors remains poorly defined. …”
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20595
Disease response in rheumatoid arthritis across four biologic therapies associates with improvement in paraoxonase-1 activity and oxylipins
Published 2024-10-01“…A targeted panel of oxylipins was evaluated by liquid chromatography-mass spectrometry/mass spectrometry in a subset of patients with the lowest and highest 6-month Disease Activity Score 28 (DAS28)-C reactive protein (CRP) responses in each treatment group.Results PON1 activity generally increased in the entire cohort after 6 months of new biologic therapy, showing the greatest, most consistent increases in the TCZ group. …”
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20596
Exploring the ElectroRetinoGraphy as a biomarker for predicting and monitoring therapeutic response to antidepressants in major depressive disorder: study protocol for the MESANTID...
Published 2025-04-01“…At the inclusion visit, prior to starting their antidepressant treatment, patients will undergo various assessments, including clinical and sleep questionnaires, as well as ERG tests. Patients will initiate their antidepressant treatment the day after the inclusion visit. …”
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20597
Clinical and genetic analysis of ERCC8-Related cockayne syndrome: hepatic dysfunction as a biomarker, anhidrosis as a rare feature, and rehabilitation outcomes for ankle contractur...
Published 2025-08-01“…ObjectivesCockayne syndrome (CS), a rare hereditary neurodegenerative disorder caused by pathogenic variants in ERCC6 (CSB) and ERCC8 (CSA), often clinically overlaps with cerebral palsy (CP), leading to misdiagnosis. This study evaluates the role of genetic testing in differential diagnosis, examines hepatic dysfunction as a biomarker of disease severity, and delineates clinical characteristics of CSA-related CS.MethodsA retrospective case series of eight CSA-related CS patients was conducted. …”
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20598
Neoadjuvant camrelizumab plus chemotherapy or apatinib for resectable stage IIA–IIIA NSCLC: a multicenter, two-arm, phase II exploratory trial
Published 2025-07-01“…Trial registration. NCT04379739, initiated on July 26, 2020.…”
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20599
Application of multi-objective neural network algorithm in industrial polymerization reactors for reducing energy cost and maximising productivity
Published 2024-12-01“…The decision variable plots show that both initiators in the reacting zone highly affected the optimal solution with the opposite action.…”
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20600
Regorafenib versus local standard of care in patients with grade 2–3 meningioma no longer eligible for loco-regional treatments: a phase II randomized controlled trial (the MIRAGE...
Published 2025-08-01“…Methods The MIRAGE trial (NCT06275919) is a multicenter, open-label, controlled, randomized phase 2 clinical trial evaluating grade 2/3 meningioma patients who have progressed following surgery and radiotherapy. …”
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