Mortality of metallo-β-lactamase-producing Enterobacterales bacteremias with combined ceftazidime–avibactam plus aztreonam vs. other active antibiotics: a multicenter target trial... by Ivan Alfredo Huespe, Emilio Felipe Huaier Arriazu, Marisa Sanchez, Vanina Stanek, Javier Alberto Pollán, Susana Bauque, Débora Ávila Poletti, Verónica Monzón, Paola Novelli Poisson, María Virginia Boutet, Eleonora Cunto, Viviana Chediack, Melina Tatiana Beloso, Victoria Rucci, Marina Lagostena, Ricardo Cabrera, María José Gutiérrez, María Georgina Gómez, Sebastián Gabriel Arias, Clarisa Taffarel, Daniel Ivulich, Maria Isabel Garzón, Wanda Cornistein, Alicia Gira, Sonia Guadalupe Kriger, Leonora Duarte, Elisa Estenssoro, Matias Mirofsky, Maximiliano Gabriel Castro, Mariana Vaena, Yolleth Andrade Pino, Emilse Díaz Lobo, Luz Guadalupe Ibáñez, Maríangeles Visus, Gustavo Olaizola, Cecilia Domínguez, Marco Antonio Flores Montes, Alejandra Rodríguez, Claudia Vaustat, Ana Paula Amato, Joaquín Ignacio Coduri Anthonioz Blanc, Federico Rafael Galluccio, Macarena Vicino, Mauro David Arias, Damián Alejandro Violi, Sandra lucila Mosca, Debora Beltran, Lilian Benito Mori, Mayra Alejandra Brañez Merida, Yolanda Marine Cortez Aguayo, María Sol García, Oscar Garcia Messina, Adriel Armándola, Néstor Iván Carrizo, María Martha Filippi, Fernando Simil, Mariana Barnes, Esteban D'urbano, Florencia Masa, Santiago Moreno, Ramiro Larrea, Valentina Tissera Mondria, Juan Camilo Monterroza, Liliana Fernandez Canigia, Emiliano Cornu, Stefanía Fernández Molina, Justina Gatti, Sofia Cornejo, Pablo Pratesi, Rodrigo Almanza Raniero Tapia, Carlos Steer, Pedro Ivan Escobar, Evelyn Rocio Ruiz, Gisella Gregori, Adriana Romani, Pascual Valdez

“…Patients with confirmed MBL bacteremia who initiated active antibiotic treatment within 24 h of MBL identification and 96 h of blood sampling were included. …”
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The effects of SGLT2i on cardiac metabolism in patients with HFpEF: Fact or fiction? by Francesca Cinti, Renzo Laborante, Luigi Cappannoli, Cassandra Morciano, Shawn Gugliandolo, Alfredo Pontecorvi, Francesco Burzotta, Maria Donniacuo, Donato Cappetta, Giuseppe Patti, Andrea Giaccari, Domenico D’Amario

“…Sodium-glucose cotransporter-2 inhibitors (SGLT2i), initially developed as glucose-lowering agents for T2D, have demonstrated promising cardiovascular benefits in patients with heart failure, including those with preserved ejection fraction (HFpEF), regardless of T2D status. …”
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Effect of restoration methods on natural regeneration in the Brazilian Atlantic Forest by Casati Fernandes H, Manhães AP, Alonso JM, Mantuano D, Martini AMZ, Saavedra MM, Andrade MT, Sansevero JBB

“…In this context, assessing restoration projects to recover native vegetation and ecosystem services is fundamental to understanding the success of these initiatives. This study evaluated the effects of different restoration techniques on the basal area, diversity, and composition of regenerating and planted species in a restoration area in the Atlantic Forest, Southeast Brazil. …”
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Cabin management and ventilation strategies for improved indoor environmental quality in passenger vehicles of developing tropics by John Omomoluwa Ogundiran, Jean-Paul Kapuya Bulaba Nyembwe, James Ogundiran, Vaibhav C. Gandhi, Anabela Ribeiro, Manuel Gameiro da Silva

“…The current study aimed to evaluate indoor air quality, thermal comfort, and ventilation performance in public transport vehicles in Lagos and to develop pragmatic improvement strategies. …”
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Use of approved cefazolin based intramammary dry goat treatment and its effects on the milk microbiota by Delower Hossain, Filippo Biscarini, Valentina Monistero, Paola Cremonesi, Bianca Castiglioni, Anoar Jamai Masroure, Alessandro Marinoni, Sara Fusar Poli, Matteo Mezzetti, Maria Filippa Addis, Valerio Bronzo, Erminio Trevisi, Paolo Moroni

“…Therefore, this study was designed to evaluate the effect of an approved cefazolin-based intramammary treatment on the milk microbiota of Alpine dairy goats during the dry and early lactation periods. …”
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Plant Diversity, Productivity, and Soil Nutrient Responses to Different Grassland Degradation Levels in Hulunbuir, China by Yuxuan Wu, Ping Wang, Xiaosheng Hu, Ming Li, Yi Ding, Tiantian Peng, Qiuying Zhi, Qiqige Bademu, Wenjie Li, Xiao Guan, Junsheng Li

“…It is essential to accurately evaluate grassland degradation and elucidate its impacts on the vegetation–soil relationship. …”
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Transcriptional landscape and predictive potential of long noncoding RNAs in peritoneal recurrence of gastric cancer by Xiao-Xia Cai, Guo-Ming Chen, Zi-Qi Zheng, Yi-Xin Yin, Shuang Wang, Li Qiao, Xiao-Jiang Chen, Bai-Wei Zhao, Jin-Ling Duan, Cheng-Cai Liang, Ruo-Peng Zhang, Cheng-Zhi Wei, Fei-Yang Zhang, Bo-Wen Huang, Ze-Xian Liu, Zhi-Wei Zhou, Dan Xie, Mu-Yan Cai, Shu-Qiang Yuan, Yuan-Fang Li, Run-Cong Nie

“…A score model was constructed using the LASSO regression model and nomogram COX regression and evaluated using receiver operating characteristic curves. …”
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A nanoencapsulated oral formulation of fenretinide promotes local and metastatic breast cancer dormancy in HER2/neu transgenic mice by Maria Laura De Angelis, Federica Francescangeli, Eleonora Aricò, Paola Verachi, Massimo Zucchetti, Cristina Matteo, Elena Petricci, Emanuela Pilozzi, Isabella Orienti, Alessandra Boe, Adriana Eramo, Rachele Rossi, Tiberio Corati, Daniele Macchia, Anna Maria Pacca, Ann Zeuner, Marta Baiocchi

“…The retinoic acid derivative fenretinide (FeR) was previously evaluated in Phase I-III clinical trials but, despite its excellent tolerability and antitumor activity in preclinical models, showed limited therapeutic efficacy due to poor bioavailability. …”
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Material design toward a thermodynamically stable Co–Cr–Fe–Al Heusler-type phase by A. Omar, F. Börrnert, M. Richter, J. Trinckauf, F. Heinsch, C. G. F. Blum, V. Romaka, S. Rodan, F. Steckel, M. Haft, S. Hampel, S. Beckert, A. Thomas, C. Hess, A. U. B. Wolter, W. Löser, B. Büchner, S. Wurmehl

“…As an exemplary case study, we consider the Heusler-like phase Co2Cr0.6Fe0.4Al, which was initially proposed to be a half-metallic ferromagnet; but this composition undergoes phase decomposition due to solid-state immiscibility. …”
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Correlation between blood pressure control levels and long-term patency of saphenous vein grafts after coronary artery bypass grafting: a retrospective case-control study by Meng Deng, Didi Wen, Yujie Song, Linli Zhao, Yang Cui, Jialin Xin, Rui Liu, Yufeng Qiu, Dongxu Yan, Wei Yi, Minwen Zheng, Yang Sun

“…Methods: This retrospective, single-center, non-blinded case-control study initially enrolled 500 patients who underwent CABG at the Department of Cardiovascular Surgery, Xijing Hospital. …”
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Qualitative and Quantitative Blood Cell Disorders Among High‐Level Antiretroviral Therapy‐Experienced Children in Northwest Ethiopia: A Cross‐Sectional Study by Dereje Mengesha Berta, Biruk Bayleyegn, Solomon Getawa, Zewudu Mulatie, Tiruneh Adane, Elias Chane, Bisrat Birke Teketelew, Melak Aynalem

“…Besides, the shape, size, color, distribution, cytoplasmic inclusions of red blood cells (RBCs), and structures of other major cell lines were meticulously evaluated using a stained blood smear preparation. …”
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Population-level health and economic impacts of introducing Vaccae vaccination in China: a modelling study by Qiong Zhang, Xun Zhuang, Min Liu, Gang Qin, Xiao Zang, Jun-Jie Mao, Wan-Lu Yue, Pei-Yao Zhai, Chun-Hu Li

“…We aim to assess the population-level health and economic impacts of introducing Vaccae vaccination to inform policy-makers.Methods We evaluated a potential national Vaccae vaccination programme in China initiated in 2024, assuming 20 years of protection, 90% coverage and US$30/dose government contract price. …”
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Development and Validation of an Adult Periodontal Health Knowledge and Belief Questionnaire in Thai Adults by Patrika Bodhidatta, Paswach Wiriyakijja, Pimchanok Sutthiboonyapan

“…Methods: The ALPHABET questionnaire, initially composed of 70 items focusing on periodontal health knowledge (ALPHA-K) and belief (ALPHA-B), underwent thorough development and validation via expert panel review. …”
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Patterns of recurrence after curative D2 resection for gastric cancer: Implications for postoperative radiotherapy by Jing Xu, Li Shen, Yongjie Shui, Wei Yu, Qingqu Guo, Risheng Yu, Yulian Wu, Qichun Wei

“…Peritoneal, regional, local, and distant recurrence initially occurred in 51 (6.6%), 151 (19.4%), 56 (7.2%), and 164 (21.1%) patients, respectively. …”
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Combination Treatment with Free Doxorubicin and Inductive Moderate Hyperthermia for Sarcoma Saos-2 Cells by Valerii E. Orel, Anatolii G. Diedkov, Vasyl V. Ostafiichuk, Sergii A. Lyalkin, Igor O. Tkachenko, Denys L. Kolesnyk, Valerii B. Orel, Olga Yo. Dasyukevich, Oleksandr Yu. Rykhalskyi, Oleksii V. Movchan, Alexander Yu. Galkin, Anna B. Prosvietova

“…<b>Conclusions</b>: IMH enhanced DOX-induced cytotoxicity in Saos-2 cells by initiating ROS-mediated apoptosis and reducing heterogeneity of cellular responses.…”
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Protocol for a randomized controlled trial of patient–portal–based screening for substance use among people with HIV by Eric Roessler, Daniela Zimmer, Jon Grant, Harold Pollack, Basmattee Boodram, Jessica Schmitt, Jessica Schmitt, Eleanor Friedman, Jade Pagkas-Bather, Jade Pagkas-Bather, Russell A. Brewer, Jessica Ridgway, Neda Laiteerapong, Neda Laiteerapong

“…BackgroundAchieving Equity in Patient Outcome Reporting for Timely Assessments of Life with HIV and Substance Use (ePORTAL HIV-S) is a research project funded by the National Institute for Drug Abuse to implement and evaluate multi-level interventions to decrease barriers to substance use screening and treatment for PLWH. …”
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Early prescription of quadruple therapy in acute decompensated heart failure with reduced ejection fraction: A propensity score‐matched analysis by Luis E. Echeverría, Lyda Z. Rojas, Angie Yarlady Serrano‐García, Daniel Botero, Karen Andrea García‐Rueda, Ángela Torres‐Bustamante, Diana Ivonne Cañón‐Gómez, Juan Sebastián Salcedo, Alexandra Hurtado‐Ortiz, Jaime A. Rodríguez, Sergio A. Gómez‐Ochoa

“…Conclusions In this HFrEF cohort, early initiation of comprehensive GDMT during ADHF hospitalization was associated with improved clinical outcomes. …”
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Clinical efficacy of elexacaftor-tezacaftor-ivacaftor in two siblings with homozygous I1234V mutation cystic fibrosis: A prospective case series by Mohammed Alzaid, Turki Alshahrani, Raed Alotaibi, Gawahir Mukhtar, Alanood Alanazi, Hammad Alsadoon, Safa Eltahir, Ahmed Aldraihem, Wadha Alotaibi

“…Baseline assessments included spirometry, body-mass index (BMI), sputum microbiology, liver biochemistry and high-resolution chest CT. ETI was initiated according to weight-based dosing and patients were reviewed at 6 and 8 months. …”
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Type 2 diabetes mellitus with chronic kidney disease benefits from long-term restriction of dietary protein intake: a 10-year retrospective cohort study by Danfeng Liu, Qiuling Li, Runli Jia, Weiting He, Xuan Zhao, Mengting Pan, Xiaojie Chen, Yanhui Wang, Yaxi Zhu, Hanchen Hou, Jianteng Xie, Wenjian Wang

“…The primary outcomes included initiation of dialysis, progression to end-stage renal disease, renal transplant, serum creatinine doubling, cardiovascular and cerebrovascular diseases. …”
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The Photocatalytic Degradation of Enrofloxacin Using an Ecofriendly Natural Iron Mineral: The Relationship Between the Degradation Routes, Generated Byproducts, and Antimicrobial A... by Sindy D. Jojoa-Sierra, Efraím A. Serna-Galvis, Inés García-Rubio, Maria P. Ormad, Ricardo A. Torres-Palma, Rosa Mosteo

“…Therefore, in this work, the capacity of a natural iron material (NIM) in photo-treatments, generating reactive species, to remove the antibiotic enrofloxacin and decrease its associated AA from water is presented. Initially, the fundamental composition, oxidation states, bandgap, point of zero charge, and morphological characteristics of the NIM were determined, denoting the NIM’s feasibility for photocatalytic processes. …”
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