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A High-Throughput Biosensing Approach for Rapid Screening of Compounds Targeting the hNav1.1 Channel: Marine Toxins as a Case Study
Published 2025-03-01“…It combines a red fluorescent dye sensitive to transmembrane potentials with CHO cells stably expressing the hNav1.1 α-subunit (hNav1.1-CHO). In the initial screening mode, the tested compounds were mixed with pre-equilibrated hNav1.1-CHO cells and dye to detect potential agonist effects via fluorescence enhancement. …”
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1802
DNN-based Software Reliability Model for Fault Prediction and Optimal Release Time Determination
Published 2025-10-01“…This paper introduces a Dense Neural Network (DNN)-based model that predicts both detected and corrected faults using data from the initial testing phase. …”
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Ni–Zn bimetal-organic framework nanoprobes reinforced polymeric coating to achieve dual-responsive warning of coating damage and interfacial corrosion
Published 2025-06-01“…The coatings with dual-responsiveness for coating defect and steel corrosion are constructed by incorporating synthesized nanoprobes composed of metal organic frameworks (Ni–Zn-MOFs) loaded with Rhodamine B (RhB@MOFs). The initial damage to the coating causes an immediate intensification of fluorescence, while the specific ionic-recognition characteristic of RhB with Fe3+ results in an evident fluorescence quenching, enabling the detection of coating damage and corrosion. …”
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Influence of External Light on Ultra-Weak Photon Emission of Fruits: Forensic Differentiation of Organic and Conventional Fruits
Published 2025-03-01“…The results indicated that, following the initial induced response, all fruit types stabilised to a spontaneous UPE state after approximately 60 min in darkness. …”
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MRI based volumetric lung nodule assessment - a comparison to computed tomography
Published 2025-04-01“…Patients were included if foci ≥6 mm were detected in CT during the initial screening round, resulting in 23 participants with 47 pulmonary nodules. …”
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Buried PE Pipeline Location Method Based on Double-Tree Complex Wavelet Cross-Correlation Delay
Published 2024-11-01Get full text
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1811
AI-CMCA: a deep learning-based segmentation framework for capillary microfluidic chip analysis
Published 2025-07-01“…Here, we present AI-CMCA, an artificial intelligence framework designed for capillary microfluidic chip analysis, which automates fluid path detection and tracking using deep learning-based segmentation. …”
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Analysis of China’s High-Speed Railway Network Using Complex Network Theory and Graph Convolutional Networks
Published 2025-04-01“…Then, this research developed three novel GCN models to identify key nodes, detect community structures, and predict new links. …”
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Psychosocial determinants of oral health outcomes in young children
Published 2024-12-01Get full text
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1814
Transfer learning for securing electric vehicle charging infrastructure from cyber-physical attacks
Published 2025-03-01“…Traditional Intrusion Detection Systems (IDS) for EV chargers struggle to detect novel or unexpected attacks due to their usage of predetermined signatures and limited detection capabilities. …”
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RNA multi-omics in single cells reveal rhythmical RNA reshaping during human and mouse oocyte maturation
Published 2025-05-01“…Defects of epi-transcriptome features, including m6A, m6Am, m7G, and poly(A) structure of maternal RNA in the oocytes with poor quality, were detected. Conclusions Our results provided a valuable tool for RNAomics research and data resources provided novel insights into human oocyte maturation, which is helpful for IVM and oocyte selection for ART.…”
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Development and validation of an integrative 54 biomarker-based risk identification model for multi-cancer in 42,666 individuals: a population-based prospective study to guide adva...
Published 2025-08-01“…Our effective risk stratification model not only enhances early cancer detection but also lays the foundation for the targeted application of advanced screening methods, including but not limited to multi-omics technologies and endoscopy. …”
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Unsupervised Cross-Domain Polarimetric Synthetic Aperture Radar (PolSAR) Change Monitoring Based on Limited-Label Transfer Learning and Vision Transformer
Published 2025-05-01“…Moreover, many related methods can only detect binary changes in PolSAR images and struggle to track the detailed land cover changes. …”
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CHANGES OF 8-OXO-2'-DEOXYGUANOSINE LEVEL IN MOUSE LIVER CELLS DNA IN CASE OF ACUTE TOXIC STRESS
Published 2016-12-01Get full text
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1819
Design of an Intelligent Driver-Passenger Monitoring System for Metro Trains Based on Device-Edge-Cloud Integration
Published 2025-04-01“…The system assigns differentiated safety constraint factors and penalty mechanisms based on the severity of impact from driver violations on operational safety, to quantify safety risks of detected violations and guide response actions. The system alerts the driver through an onboard voice alarm system to intervene at the initial stage of any detected violation. …”
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