Impact of the initial administration of an antiretroviral drug with latency reversal properties on the HIV reservoir size by Erick De La Torre Tarazona, Elisa Moraga, Raúl Vaquer, Sonsoles Sánchez-Palomino, Elisa de Lazzari, Laura Luna, Sònia Vicens-Artés, Lucio Jesús García Fraile, Joaquim Peraire, Mercedes Garcia-Gasalla, Luz Balsalobre, Sergio Guillén Martínez, Luis Fernando López Cortés, Inma Jarrín, Sergio Serrano-Villar, José Alcamí, Santiago Moreno, CoRIS Cohort

“…Moreover, no significant differences in the HIV transcriptional activity, assessed by ca-HIV-RNA levels or HIV-RNA/HIV-DNA ratios, were observed between the MVC-initiation and non-MVC-initiation groups. In conclusion, starting ART with a drug with HIV latency reversing activity at detectable VL phase may contribute to a greater reduction in the HIV-DNA reservoir. …”
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On Analytical Methods in Neuroblastoma Detection by R. Martínez-Díaz, J. Balaguer, L. M. Sánchez Ruiz, P. Bello, V. Castel, G. Perís-Fajarnés

“…Nonlinear dynamics of cancer recurrence are known to be governed by several factors as initial tumour size, number of metastatic sites, or quantity of drug resistant cells. …”
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Randomised controlled trial to evaluate the effectiveness of using the RD-1-based C-Tb skin test as a replacement for blood-based interferon-γ release assay for detection of, and initiation of preventive treatment for, tuberculosis infection: RID-TB:Dx study protocol by Marc Lipman, Ibrahim Abubakar, Chris Griffiths, Penny Whiting, Robert Horne, Alex Ghanouni, Heinke Kunst, Mike Mandelbaum, Molebogeng X Rangaka, Karen Sanders, Peter J White, Angela Crook, Dominik Zenner, Trinh Duong, Vanessa Hack, Julian Surey, Yohhei Hamada, Henry Bern, Joanna Calvert, Marie Francis, Amy Louise Clarke, Ellen Owen-Powell, Helen L Booth

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Analysis of unqualified ALT results in the initial screening and re-examination of blood donors in Changchun, China by HE Min, CUI Jingru, WANG Zhiyong, MA Yang

“…The unqualified rates of ALT were statistically analyzed according to the blood collection sites and the initial screening detection equipment. The samples after ALT pre-donation screening were tested in the laborator, and the unqualified rates of ALT in the initial screening and the laboratory, the non-conformity rate of the results and the distribution range of ALT values were statistically analyzed according to the blood collection sites and the initial screening detection equipment. …”
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Establishment of genetic transformation system and initial report of transform BIO and bio gene in Petunia hybrida by LI Ying, LIU Jiyan, HU Jiangqin, CHEN Zhehao, HU Lingzhi, WANG Lilin

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Real-time analysis of initiation regulation systems during the progression of the reconstituted chromosomal replication cycle by Koki Kanoh, Masayuki Su’etsugu

“…Abstract Chromosome replication in Escherichia coli is primarily regulated at the initiation stage, where the DnaA protein activates replication at the chromosomal origin, oriC. …”
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Multiple sarcomatoid carcinoma of the small intestine with perforation as the initial symptom: case report and review of the literature by Jixin Fu, Qingbin Kong, Xin Sui, Xinjian Wang

“…Increased awareness among clinicians is crucial for early detection and intervention.…”
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FXTAS presenting with cervical dystonia as the initial symptom: Considering FXTAS in the clinical evaluation of cervical dystonia by Homare Funasaka, Serika Kanazawa, Sachiko Kamada

“…This suggests that, even when FXTAS initially presents as cervical dystonia, the MCP sign can remain a reliable diagnostic feature for early detection.This case highlights that early FXTAS may mimic idiopathic cervical dystonia and that considering FXTAS during the clinical evaluation of cervical dystonia can enable early diagnosis.…”
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Diabetes and prediabetes prevalence through a community-based screening initiative in Alqunfudah, Saudi Arabia by Saleh Ahmed Alshaikhi, Ahmed Madini Alamri, Ibrahim Yahya Alzilai, Ageel Ahmad Alghanimi, Ali Mohammad Alrufaidi, Ahmed Mohammed Alrufaidi, Ahmed Elsayed Bader, Ahmed Abushaisha Abdelmoniem, Ayoub Ali Alshaikh, Omar Ahmed Alshaikhi, Mohammed Ahmed Alshaikhi, Ramy Mohamed Ghazy

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Quantum Dot-Based Optical Fiber Sensor for Flow Velocity Sensing at Low Initial Temperatures by Lei Sun, Yekun Cao, Rui Zhou, Min Li, Xiaoyan Wen, Ming-Yu Li, Shuo Deng, Sisi Liu, Haifei Lu

“…However, the high sensitivity of current hot wire flowmeters is often achieved at the expense of increasing the initial temperature, which imposes significant limitations when measuring blood or other temperature sensitive fluids. …”
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Analysis of Environmental Field Characteristics of Convective Initiation Triggered by Thunderstorm Gust Fronts in Beijing Area by Na HE, Xiaoding YU, Qinglan DING, Xian XIAO, Nan XING, Ke LIU

“…In order to enhance the understanding of the environmental field characteristics of the convective regeneration triggered by thunderstorm gust fronts.Based on Beijing sounding observation， automatic stations， S-band Doppler radar and new detection data to analyse environmental field characteristics of two typical cases in which convection initiation triggered by thunderstorm gust fronts.The results show that： （1） One type is convection triggered by collision of multiple gust fronts or the encounter of gust fronts with other boundary layer convergence lines in the region with high Convective Available Potential Energy （CAPE） and sufficient water vapor （collision triggering）.In this type， the vertical velocity of two collision gust fronts is much larger than that of a single gust front.Strong upward movement is easy to provide good lifting conditions for the triggering of convection， and convection is easy to trigger.（2） The other type is the gust front triggers convection in the unstable region （non-collision trigger）.In this type， the low-level wind direction is perpendicular to the gust front， which is conducive to the strong convergence between the ambient wind near the ground and the gust front.Meanwhile， the updraft of the convection triggered by the gust front tends to be vertical， which is beneficial to convective initiation.（3） By comparing the environmental field of gust fronts trigger and non-trigger Convective Initiation （CI） cases， the results show that there are deep wet convection potential with high CAPE and low Convective Inhibition （CIN） of the environment field in these cases which CI are triggered by gust fronts.The wind profile and microwave radiometer observations indicate that there are cold dry advection at the upper level and warm wet advection at the lower level in most cases CI triggered by the gust fronts.In most cases which gust fronts trigger CI occur at the wind speed or wind direction convergence areas with high CAPE.（4） In cases which non-triggered CI， vertical distribution of environmental field is not conducive to the regeneration and development of convection， and gust fronts pass the area which are divergence or there are low CAPE and high CIN.These conditions are adverse to convection triggering.…”
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Call for regulation of social media health content: an initiative of the Italian Association of Hospital Dermatologists (ADOI) by Fortunato Cassalia, Andrea Danese, Carmine D'Acunto, Antonio Russo, Corrado Zengarini, Ignazio Stanganelli, Francesco Cusano, Fabrizio Fantini, Salvatore Amato, Davide Melandri, Cesare Massone, Anna Belloni Fortina

“…While platforms like Instagram, Facebook, and Twitter offer significant opportunities to raise awareness about skin health, promote preventive measures, and encourage early detection of dermatological conditions, the unregulated dissemination of health information poses substantial risks due to misinformation. …”
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Analysis of Enticement Detection using Information Technology by Baiyang Jia

“…Since its emergence, enticement detection using information technology, as a special means of investigation, has been widely used in judicial practice to combat crime due to its inherent advantages of initiative and efficiency. …”
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Preserving cognitive function in patients with Alzheimer's disease: The Alzheimer's disease neuroprotection research initiative (ADNRI) by Jie Liu, Heleen vanBeusekom, Xian‐Le Bu, Gong Chen, Paulo Henrique Rosado de Castro, Xiaochun Chen, Xiaowei Chen, Andrew N. Clarkson, Tracy D. Farr, Yuhong Fu, Jianping Jia, Jukka Jolkkonen, Woojin Scott Kim, Paula Korhonen, Shen Li, Yajie Liang, Guang‐Hui Liu, Guiyou Liu, Yu‐Hui Liu, Tarja Malm, Xiaobo Mao, Joaquim Miguel Oliveira, Mike M. Modo, Pedro Ramos‐Cabrer, Karsten Ruscher, Weihong Song, Jun Wang, Xuanyue Wang, Yun Wang, Haitao Wu, Lize Xiong, Yi Yang, Keqiang Ye, Jin‐Tai Yu, Xin‐Fu Zhou, Marietta Zille, Colin L. Masters, Piotr Walczak, Johannes Boltze, Xunming Ji, Yan‐Jiang Wang

“…The Alzheimer's Disease Neuroprotection Research Initiative's objective is to facilitate coordinated, multidisciplinary efforts to develop systemic neuroprotective strategies to combat AD. …”
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Clustering of ECG Signals Based on Fuzzy Neural Network with Initial Weights Generated by Genetic Algorithm by Elaheh Sayari, Mahdi Yaghoobi

“…Early detection of heart diseases/abnormalities can prolong life and enhance the quality of living through appropriate treatment. …”
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Distant recurrence of non‐muscle invasive bladder cancer 8 years after initial treatment by Mahoro Watanabe, Naoki Kawamorita, Tetsuro Shiraiwa, Tomonori Sato, Takuma Sato, Yoshihide Kawasaki, Shinichi Yamashita, Akiko Ebata, Satoko Sato, Akihiro Ito

“…Initially, she was diagnosed with metastatic left breast cancer of the left accessory mamma by needle biopsy of an axillary tumor. …”
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Case Report: Severe Colonic Crohn Disease Initiated after Liver Transplantation Requiring Surgery by Gabriela Feres Sapienza, Rodrigo Ambar Pinto, Italo Beltrão Simões, Maria Clara Traldi, Carlos Frederico Marques, Luiz Augusto Carneiro D'Albuquerque, Manuel Rocha, Sergio Carlos Nahas, Camila Marchiolli, Felipe Lourenço Ledesma

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IMPACT OF MOLECULAR GENETIC METHODS ON THE INITIATION OF CHEMOTHERAPY IN MULTIPLE DRUG RESISTANTTUBERCULOSIS PATIENTS IN ARKHANGELSK REGION by P. I. Eliseev, A. Detjen, R. Dacombe, P. Pillips, S. B. Squire, A. O. Maryandyshev

“…The use of molecular genetic tests in smear-positive patients (AFB+) resulted in the reduction of the time period before initiation of MDRTB treatment by 50 and 66 days (median) versus culture by BacTAlert and absolute concentration on Lowenstein-Jensen medium respectively (p <0.001).Patients with a negative smear (AFB-), in whom MDR TB was detected by molecular genetic methods started treatment by 78 days earlier (median) versus patients who had culture (Lowenstein-Jensen, p < 0.001). …”
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EEG indices in patients with high risk of ischemic stroke as predictors of initial disturbed cerebral circulation by N. A. Isaeva, Ph. S. Torubarov, Z. Ph. Zvereva

“…Abnormal changes were detected in EEG in patients with high risk of ischemic stroke (higher level than in the population). …”
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X-linked adrenoleukodystrophy in a 6-year-old boy initially presenting with psychiatric symptoms by Faruk İncecik, M Özlem Hergüner, Gülen Mert, Neslihan Önenli-Mungan, Serdar Ceylaner, Deniz Kör, Şakir Altunbaşak

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