Mesangial cell-derived CircRNAs in chronic glomerulonephritis: RNA sequencing and bioinformatics analysis by Ji Hui Fan, Xiao Min Li

“…Pro-inflammatory cytokines and cell cycle stages were detected by Enzyme-linked immunosorbent assay (ELISA) and Flow Cytometry experiment, respectively. …”
Get full text

Refractory postoperative Staphylococcus hominis bacteremia in a patient with an ACTH-producing pancreatic neuroendocrine neoplasm: a case report by Ryuta Muraki, Yoshifumi Morita, Kyota Tatsuta, Shinya Ida, Ryo Kitajima, Amane Hirotsu, Makoto Takeda, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Atsuko Fukazawa, Go Kuroda, Keisuke Kakizawa, Hiroya Takeuchi

“…On postoperative day 11, catheter-associated bacteremia occurred. Initially, meropenem hydrate and vancomycin hydrochloride were administered empirically. …”
Get full text

Effect of Simple Reaction Speed Training on Executive Function of the Elderly with Mild Cognitive Impairment by Hong ZHANG, Xiaofei WEI, Congyong LIU, Kaili QIAN, Chun LI, Rang LI, Yuan JIANG

“…Moreover, the serum brain-derived neurotrophic factor in the blood before and after intervention was detected by using enzyme linked immunosorbent assay (ELISA), respectively.Results:Compared with before intervention, the scores of conversion, working memory, planning, task monitoring, MI, total standard scores, TMT-B and interference in the observation group after intervention for three months were significantly lower, KST, TJT, ZMT, total standard scores and level of serum BDNF of the observation group after intervention were significantly higher (<italic>P</italic>&lt; 0.05); compared with the control group, the scores of conversion, task initiation, working memory, planning, BRI, MI, total standard scores, TMT-B and interferences of the observation group were significantly lower, and RSCT, KST, TJT, ZMT, total standard scores and level of serum brain-derived neurotrophic factor (BDNF) of the observation group were significantly high (<italic>P</italic>&lt; 0.05).Conclusion:Simple reaction speed training can improve the executive function, brain nerve function, and effectively delay cognitive decline of elderly with MCI.…”
Get full text

Changes in cerebral haemodynamics in patients depending on the severity and catamnesis of combat traumatic brain injury by I. Chernenko

“…The traumatic factor initiates a series of pathological processes, including immune, hemodynamic, metabolic, etc. …”
Get full text

Prevalence of pilus islets and association with clonal complex in Streptococcus pneumoniae isolated from children in Suzhou, China by Jiaming Shen, Xiaofei Liu, Lili Huang, Youyi Zhang, Yunzhen Tao, Mengzhen Wang, Genming Zhao, Xuejun Shao, Tao Zhang

“…Multi-locus sequence typing (MLST) was conducted to identify the sequence types and clonal complex (CC). PI-1 and PI-2 were detected by PCR assays for the rlrA and sipA genes, respectively. …”
Get full text

THE USE OF CRYOCONSERVATED PLACENTA FOR PREVENTION OF PATHOLOGIC SCAR FORMATION OF THE HEAD AND NECK AT THE INTRA- AND POSTOPERATIVE STAGE IN PLANNED SURGERY by O.A. Toropov, D.S. Avetikov, K.P. Lokes, D.V. Steblovskyi, V.M. Skrypnyk, R.A. Prykhidko

“…With the development of technology, it became possible to detect the phenotypic and functional heterogeneity of cell types. …”
Get full text

Genome drafting of nosocomial infection CRE Klebsiella pneumoniae confirming resistance to colistin and eravacycline, carrying blaNDM-1, mcr-1, and blaKPC-2, in neonatology from No... by Xinlong Zhou, Kailash Wagh, Guizhen Lv, Devender Sharma, Wei Lei

“…Efflux pump genes and aminoglycoside resistance genes were also detected, providing a multifaceted defence against antibiotics. …”
Get full text

Combined Pharmacological and surgical treatments for recurrent chemical peritonitis due to rupture of a bilateral mature cystic teratoma: a case report by Sho Kudo, Hideaki Tsuyoshi, Kino Tsuji, Yoshiaki Tanaka, Makoto Orisaka, Yoshio Yoshida

“…Intravenous administration of Prophylactic antibiotics was initiated. As no bacteria were detected in the blood cultures, we started oral prednisolone (5 mg/day) to treat the recurrent chemical peritonitis-induced inflammation. …”
Get full text

Modification of IPI Method for Extraction of Short-Term and Imminent OLR Anomalies and Case Study of Two Large Earthquakes by Maoning Feng, Pan Xiong, Weixi Tian, Yue Liu, Changhui Ju, Cheng Song, Yongxian Zhang

“…The Pattern Informatics Method (PI) was initially developed for medium-to-long-term earthquake prediction by analyzing changes in seismic activity. …”
Get full text

A tip of the iceberg: genome survey indicated a complex evolutionary history of Garuga Roxb. species by Dongbo Zhu, Rui Rao, Yu Du, Chunmin Mao, Rong Chen, Liangliang Yue

“…A total of 330,999 SSRs were detected, with mononucleotide repeats being the most abundant at 70.16%, followed by dinucleotide repeats at 20.40%. …”
Get full text

Experience of cladribine tablets usage in the treatment of multiple sclerosis in the Multiple Sclerosis Centre of the Khanty-Mansi Autonomous Area — Yugra by A. A. Sokolova, L. I. Anischenko, L. S. Zemlyanushin, E. A. Rubtsova

“…In addition, all patients had no disease activity on MRI after starting cladribine therapy compared to the baseline data before starting cladribine therapy, when Gd+ lesions were detected on T1-weighted images in 50 (92.5%) patients. …”
Get full text

PO18 | Does muscle mass matter? Appendicular lean mass as a determinant of anti-XA activity in elderly patientes

“…However, aging alters body composition, notably reducing lean mass, which is not detectable by body weight and may affect DOAC pharmacokinetics. …”
Get full text

Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancer by Luis Aparicio, Laura Crowley, John R. Christin, Caroline J. Laplaca, Hanina Hibshoosh, Raul Rabadan, Michael M. Shen

“…Abstract Background Despite extensive analysis, the dynamic changes in prostate epithelial cell states during tissue homeostasis as well as tumor initiation and progression have been poorly characterized. …”
Get full text

Improving ototoxicity monitoring in patients receiving aminoglycosides using a novel digital approach: a quality improvement project by Andrew Jones, Francis Drobniewski, Michael Loebinger, Emily Frost, Julie Wilkins, Presanna Premachandra, Anand Shah, Su Madge, Nicholas J Simmonds, Ricardo J José, Jamie Cheong, Shereen Boreland, Elaine Shattock, Elaine Bowman, Barbara Belkarty, Imogen Felton, Emem-Fong Ukor, Janet Stowell

“…Patient identification using referral and reporting systems initially improved adherence from 36% to 88% (p=0.03) during PDSA 1. …”
Get full text

Enhancing personalised care in COPD exacerbation: the role of cardiac/inflammatory biomarkers by Pouria Khashayar, Kenneth Spearpoint, Patricia Khashayar, Manivannan Srinivasan, Thida Win

“…It has gained even more attention in recent years because of its potential role in detecting subclinical CVD in AECOPD patients.5 In other words, elevated troponin levels (>14 ng/L) have been linked with a significantly higher risk of underlying ischaemic heart disease (IHD) (up to 70%) and subsequently experiencing a major adverse CVD event (up to 23.1%) within the next 90 days. …”
Get full text

The Margin of Stability During a Single-Turn Pirouette in Female Amateur Dancers: A Pilot Study by Annalisa Dykstra, Ashley Kooistra, Nicole Merucci, David W. Zeitler, Gordon Alderink

“…The magnitude of both versions of the MoS was greatest at turn initiation and toe-touch, which was associated with two foot contacts. …”
Get full text

A polymorphism in the glucocorticoid receptor gene is associated with refractory hypotension in premature infants by Kei Ogasawara, Maki Sato, Koichi Hashimoto, Takashi Imamura, Hayato Go, Mitsuaki Hosoya

“…Results: Of the four GR polymorphisms, only the BclI polymorphism was detected. The genotype distribution was as follows: C/C, 33; C/G, 8; and G/G, 0 infants. …”
Get full text

Emotional and visual responses to trypophobic images with object, animal, or human body backgrounds: an eye-tracking study by Pengfei Yu, Li Yu, Li Yu, Yuting Li, Cheng Qian, Jia Hu, Weiyi Zhu, Fang Liu, Fang Liu, Qi Wang, Qi Wang, Qi Wang

“…No significant difference was detected between the power of trypophobic images with human body backgrounds and objects backgrounds. …”
Get full text

Lack of canonical activities of connexins in highly aggressive human prostate cancer cells by Catalina Asencio, Loreto Véliz, Emilia Flores-Faúndez, Lorena Azócar, Carolina E. Echeverría, Verónica Torres-Estay, Viviana Orellana, Catalina Ramírez-Santelices, Paula Sotomayor, Jorge Cancino, Bredford Kerr, Ainoa Fernandez-Olivares, Mauricio A. Retamal, Juan C. Sáez, Alejandro S. Godoy

“…This data indicated that GJ and HC activities were moderately detected only in the less aggressive PCa cells, which suggest that Cxs expression in highly aggressive PCa cells could be associated to channel-independent roles.…”
Get full text

Knockdown of the long noncoding RNA VSIG2-1:1 promotes the angiogenic ability of human pulmonary microvascular endothelial cells by activating the VEGF/PI3K/AKT pathway by Xiaoya Hu, Yihui Zheng, Mingchu Fang, Zhongjie Liang, Chao Wen, Jing Lin, Zhenlang Lin, Shangqin Chen

“…Fluorescence in situ hybridization (FISH) assay was performed to detect the subcellular localization of lncRNA-VSIG2-1:1. …”
Get full text