Validating and utilizing dried blood spots for family screening: Screening Programme Providing Outreach for Testing Hereditary Angioedema (SPPOT-HAE) by Jane C.Y. Wong, MBBS, Dorothy L.Y. Lam, MSc, Jackie S.H. Yim, MSc, Elaine Lee, MSc, Weihong Shi, MMed, Valerie Chiang, MBBS, Philip H. Li, MD

“…Methods: In part 1, 16 Chinese C1-INH-HAE patients from 7 families participated in the validation of DBS for detecting C4, C1-INH, and functional C1-INH (fC1-INH). …”
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Molecular epidemiology and antimicrobial resistance of Salmonella at the human–macaque–environment interface in Thailand: A One Health surveillance study by Suchawan Pornsukarom, Daraka Tongthainan, Phairot Phromwat, Suwarak Wannaratana, Kulchai Nakbubpa, Sarut Muangsri

“…The findings advocate for public awareness initiatives, environmental hygiene improvements, and integrative One Health strategies to mitigate AMR dissemination at the human–animal–ecosystem interface.…”
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Gut microbiota modulates depressive-like behaviors induced by chronic ethanol exposure through short-chain fatty acids by Hui Shen, Chaoxu Zhang, Qian Zhang, Qing Lv, Hao Liu, Huiya Yuan, Changliang Wang, Fanyue Meng, Yufu Guo, Jiaxin Pei, Chenyang Yu, Jinming Tie, Xiaohuan Chen, Hao Yu, Guohua Zhang, Xiaolong Wang

“…Changes in related indicators, including the intestinal barrier, intestinal inflammation, neuroinflammation, neurotrophy, and nerve damage, were detected using Western blotting, immunofluorescence, and Nissl staining. …”
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Qualitative and Quantitative Blood Cell Disorders Among High‐Level Antiretroviral Therapy‐Experienced Children in Northwest Ethiopia: A Cross‐Sectional Study by Dereje Mengesha Berta, Biruk Bayleyegn, Solomon Getawa, Zewudu Mulatie, Tiruneh Adane, Elias Chane, Bisrat Birke Teketelew, Melak Aynalem

“…Regarding white blood cell abnormalities, leukopenia and lymphopenia were detected among 12.2% and 10.3% of study participants, respectively. …”
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Leucyl-tRNA synthetase regulates casein synthesis in dairy cows via the mTORC1-LAT1 pathway by Yongding Ke, Ximeng Du, Binglan Chen, Xi Chen, Chengchuang Song, Xingtang Fang, Yanhong Wang, Chunlei Zhang

“…It facilitates tRNA aminoacylation, initiating intracellular protein synthesis, and serves as an intracellular leucine sensor. …”
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In Vitro Evaluation of the PMN Reaction on a Collagen-Based Purified Reconstituted Bilayer Matrix (PRBM) Using the Autologous Blood Concentrate PRF by Eva Dohle, Hongyu Zuo, Büşra Bayrak, Anja Heselich, Birgit Schäfer, Robert Sader, Shahram Ghanaati

“…On the other hand, cytokines related to the PMN regenerative phenotype, like TGFβ and IL10, could be detected as higher when PRF was incubated in the presence of the PRBM. …”
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Pre-Hospital Point-of-Care Troponin: Is It Possible to Anticipate the Diagnosis? A Preliminary Report by Cristian Lazzari, Sara Montemerani, Cosimo Fabrizi, Cecilia Sacchi, Antoine Belperio, Marilena Fantacci, Giovanni Sbrana, Agostino Ognibene, Maurizio Zanobetti, Simone Nocentini

“…This enables earlier initiation of appropriate treatment, potentially improving patient outcomes and the efficiency of emergency department operations. …”
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Gain-of-function ANXA11 mutation cause late-onset ALS with aberrant protein aggregation, neuroinflammation and autophagy impairment by Qing Liu, Ye Sun, Baodong He, Haodong Chen, Lijing Wang, Gaojie Wang, Kang Zhang, Ximeng Zhao, Xinzhe Zhang, Dongchao Shen, Xue Zhang, Liying Cui

“…Significant motor neuron loss and neuroinflammation were detected by 9 months, with marked muscle dystrophy apparent by 12 months compared to wild-type controls. …”
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<i>Oropouche orthobunyavirus</i> in Urban Mosquitoes: Vector Competence, Coinfection, and Immune System Activation in <i>Aedes aegypti</i> by Silvana F. de Mendonça, Lívia V. R. Baldon, Yaovi M. H. Todjro, Bruno A. Marçal, Maria E. C. Rodrigues, Rafaela L. Moreira, Ellen C. Santos, Marcele N. Rocha, Isaque J. da S. de Faria, Bianca D. M. Silva, Thiago N. Pereira, Amanda C. de Freitas, Myrian M. Duarte, Felipe C. de M. Iani, Natália R. Guimarães, Talita E. R. Adelino, Marta Giovanetti, Luiz C. J. Alcantara, Álvaro G. A. Ferreira, Luciano A. Moreira

“…In Brazil, 13,785 cases were confirmed in 2024, with an additional 3680 reported by January 2025, according to the Ministry of Health. Initially restricted to the Amazon region, OROV has recently been detected in new areas, highlighting the need for enhanced surveillance and vector control strategies. …”
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Effects of theta burst stimulation on cognitive function and characteristics of blood oxygen alterations based on near-infrared spectroscopy in chronic schizophrenia by Chunying Gao, Guangjian Li, Xiangrong Zhang, Tongbo Lu, Zhou Wang, Chenzhi Zhou, Gang Chen, Di Ma, Wenjie Wang, Xinyu Fang, Suwan Guo, Chengbao Huang, Chao Zhou

“…The Mini-mental State Examination (MMSE) and Mattis-dementia Rating Scale Second Edition (MDRS-2) were used to assess cognitive function. fNIRS was used to detect the changes in hemoglobin signal values during the verbal fluency task (VFT) before and after TBS intervention. …”
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Release Behavior and Bioaccumulation Characteristics of Organophosphate Esters from Plastics in Marine Aquaculture by Zhi YANG, Dongni LIU, Shengnan HUANG, Xuetian DAI, Wei QIAN, Xiaoshan ZHU

“…Five OPEs—TCP, TDCPP, TnBP, TCPP, and TiBP—were detected in Artemia. We evaluated the degree of bioaccumulation using the bioaccumulation factor (BAF). …”
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Developmental trajectories in mental health through adolescence and adulthood: does socio-economic status matter? by Christine Leonhard Birk Sørensen, Oleguer Plana-Ripoll, Ute Bültmann, Trine Nøhr Winding, Pernille Bach Steen, Karin Biering

“…Conclusions This is the first study to detect the role of social support in relation to depressive symptom trajectories. …”
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Community-level mental health screening and referral using task-sharing with student volunteers in Kerala, India: a scalable model for low and middle income countries by Saju Madavanakadu Devassy, Lorane Scaria, Shyba Babu, Rajeev S.P., Lijo K.J., Amal Tom Jose, Kiran Thampi, Robin E. Gearing

“…Results The youth-led community screening is promising, as the detected incidence rate was comparable to that of screening performed by experts. …”
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Fiscal issues of government policy for the investment protection and promotion by I. A. Tsindeliani, E. G. Vasilyeva, M. A. Egorova, D. V. Tyutin, Zh. G. Popkova

“…Despite the plenty of works on the topic of legal regulation of activity of small and medium-sized businesses, this field of legislation is not developed enough to give an opportunity to conduct complex researches of theoretical and practical aspects relating to exclusively legal and financial framework of state support of the investment activity. In this article we detect and reveal general problems connected to introducing of tax frameworks of state support of promotion of investments in the conditions of existing Russian legislation. …”
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Heterogeneity symptoms of urgency in patients with benign prostatic hyperplasia by V. L. Medvedev, M. I. Kogan, T. I. Derevianko, P. V. Shornikov, M. E. Efremov, D. S. Isaeva

“…From the data reported by CUDI, spontaneous detrusor activity was detected in 49 (43.7%) patients, in 63 (56.2%) it was not registered. …”
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Lung cancer in patients with COPD and factors associated with reduced survival by S. Yu. Dobner, S. V. Fedosenko, E. O. Rodionov, N. D. Yarovoy, V. A. Petrov, S. A. Tuzikov, E. A. Starovoitova, I. A. Samykina

“…Peripheral lung cancer was detected in 45.8% of cases. Squamous cell carcinoma was noted in 54.2% of cases, adenocarcinoma – in 34.7%, large cell carcinoma – in 1.7%, small cell carcinoma – in 5.9%, and carcinoid tumors – in 2.5% of cases. …”
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Preclinical evaluation of AAV9-coSMN1 gene therapy for spinal muscular atrophy: efficacy and safety in mouse models and non-human primates by Wenhao Ma, Zhijie Wu, Tianyi Zhao, Yan Xia, Jing Qin, Xue Tian, Xin Li, Jun He, Yan Zhang, Lina Zhang, Li Li, Zheyue Dong, Zhichun Feng, Xiaoyan Dong, Wang Sheng, Xiaobing Wu

“…Peripheral organs also showed detectable levels of the vector gene, indicating effective systemic distribution. …”
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Clinical effects of Bifidobacterium Longum Subsp. Infantis YLGB-1496 on children with respiratory symptoms by Pin Li, Uma Mageswary, Adli Ali, Fahisham Taib, Thai Hau Koo, Azianey Yusof, Hua Jiang, Hanglian Lan, Weilian Hung, Min-Tze Liong, Yumei Zhang

“…Oral swabs and fecal samples were collected from participants at weeks 0, 6, and 12 to examine inflammatory cytokines.ResultsAmong the 120 toddlers initially included in the study, 115 completed the 12-week intervention (58 in the YLGB-1496 group and 57 in the placebo group). …”
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Peculiarities of acute myocardial infarction course and distribution of the somatostatin receptor analogue 99mTc-octreotide in the heart by V. V. Ryabov, A. G. Syrkina, A. A. Trusov, A. I. Mishkina, S. I. Sazonova, Yu. N. Ilyushenkova

“…An increase in hsCRP and early initiation of LV remodeling after primary anterior ST-segment elevation MI is accompanied by a pronounced accumulation of 99mTc-octreotide in the damage zone, detected using cardiac SPECT, as a result of systemic and local, in our opinion, macrophage-mediated post-infarction inflammation.…”
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Anal fistula metastasis of rectal cancer after neoadjuvant therapy: a case report by Shota Fukai, Shingo Tsujinaka, Yasuyuki Miyakura, Natsumi Matsuzawa, Yuuri Hatsuzawa, Ryo Maemoto, Nao Kakizawa, Toshiki Rikiyama

“…After completion of CRT, computed tomography (CT) revealed the primary tumor’s partial response, but a liver mass highly suggestive of metastasis was detected. This mass was later diagnosed as cavernous hemangioma 3 months after CRT initiation. …”
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