Associations of dyadic appraisal of cancer cachexia symptoms with psychological distress and quality of life in dyads of palliative care patients: a longitudinal mixed-methods stud... by Huilin Cheng, Carmen Wai Lim Leung, Jeffrey Sheung Ching NG, Kam Hung Wong, Deepa Natarajan, Lut Ming Chan, Nancy Hiu Yim NG, Tsz Wai Tsang, Wai Ming Leung, Raymond See Kit LO

“…Abstract Background Cancer cachexia (CC) is a fatal syndrome most prevalent in palliative care patients and is typically characterized by a progressive increase in weight loss and anorexia. The inability to detect and accurately appraise CC symptoms early can lead to a delayed diagnosis of CC and late initiation of symptom management, subsequently resulting in shorter survival. …”
Get full text

Occlusal vs non-occlusal modality of the loading protocol for oral implants in partially edentulous patients: a systematic review and meta-analysis by Panagiotis Kourkoutis, Rawand Shado, Ines Novo Pereira, David Madruga, Haidar Hassan

“…Future studies should explore functional and aesthetic aspects, as well as patient reported outcomes to determine any short-term differences or consider long-term follow-up with large sample sizes to detect significant clinical differences.…”
Get full text

Antibiotic resistance and pathogenic bacterial profiles in drinking and surface water in Baghdad, Iraq. by Wael Obaid, Anmar Khalaf, Jilan Shakur

“…Conclusions: The health of community members who depend on these initiatives for their drinking water may be threatened by an abundance of antibiotic-resistant bacteria and pathogenic microbes. …”
Get full text

Identification of Virulence Genes Associated with Pathogenicity of Translocating <i>Escherichia coli</i> with Special Reference to the Type 6 Secretion System by Behnoush Asgari, Jarred R. Burke, Bonnie L. Quigley, Georgia Bradford, Eva Hatje, Anna Kuballa, Mohammad Katouli

“…The HMLN-1 strain was initially tested for the presence of six virulence genes (VGs) associated with AIEC strains and an iron sequestering system. …”
Get full text

Fetal brain injury in the pump twin of a TRAP sequence with favorable postnatal outcome: a case report by Wirada Dulyaphat, Chaniga Jiratchayamaethasakul, Supakorn Chaiyakarn, Waranyu Lertrat, Chayada Tangshewinsirikul, Chaiyos Khongkhatithum

“…Case presentation A 22-year-old pregnant woman was initially misdiagnosed with a monochorionic diamniotic (MCDA) twin pregnancy complicated by single fetal demise. …”
Get full text

Revisiting the Middle Molecule Hypothesis of Uremic Toxicity: A Systematic Review of Beta 2 Microglobulin Population Kinetics and Large Scale Modeling of Hemodialysis Trials In Sil... by Maria Eleni Roumelioti, Thomas Nolin, Mark L Unruh, Christos Argyropoulos

“…Randomized controlled trials of novel dialysis modalities may require large sample sizes to detect an effect on clinical outcomes even if they enroll anuric patients. …”
Get full text

KAT7-acetylated YBX1 promotes hepatocellular carcinoma proliferation by reprogramming nucleotide metabolism by He Huang, Longfei Ren, Yongqiang Zhou, Pengyu Chen, Haixia Zhao, Shang Li, Haiping Wang, Xun Li

“…Abstract Background Lysine acetylation is a critical post-translational modification regulating tumor initiation and progression. Lysine acetyltransferase 7 (KAT7)-mediated lysine acetylation is frequently dysregulated in cancer. …”
Get full text

The inhibitory effect of Osthole on A549 lung adenocarcinoma cells and its biomarker by Yinlan Xu, Lulu Chen, Dong Liu, Bo Xue, Chaoying Li, AJab Khan, Xuehua Li, Ruling Shi

“…A total of eight natural compounds having pure plant origin were initially screened, purchased, and their potential anti-cancer activities were comprehensively and systematically evaluated against A549 lung adenocarcinoma cells. …”
Get full text

Evaluation of 4-tert-Butyl-Benzhydrylamine Resin (BUBHAR) as an Alternative Solid Support for Peptide Synthesis by Sinval E. G. Souza, Luciana Malavolta, Luiggi F. Salomoni, Eduardo M. Cilli, Shirley Schreier, Guita N. Jubilut, Clovis R. Nakaie

“…In order to rule out possible MBHAR-related commercial source effects for SPPS, we initially compared MBHAR batches acquired from three different manufacturers with homemade BUBHARs. …”
Get full text

Human papillomavirus in vulvar cancer: a systematic review by D. S. Dolgasheva, M. K. Ibragimova, E. A. Kravtsova, I. A. Tsydenova, K. A. Gaptulbarova, M. M. Tsyganov, N. V. Litviakov

“…The review included papers in which HPV was found in more than one case of vulvar tumor and if HPV DNA was detected by using polymerase chain reaction. Initially 249 articles were selected, 25 papers were included in the qualitative analysis, from which 6 case-control studies that fully met the specified inclusion criteria were further analyzed. …”
Get full text

Evaluation of the roughness, color match, and color stability of two monochromatic composite resins: a randomized controlled laboratory study by Iara Campos Santana, Sabrina Sobral de Oliveira, Karolina Pena Botelho, Renan Leonardi de Oliveira Rigotti, José Cristiano Ramos Glória, Adriana Maria Botelho, Dhelfeson Willya Douglas-de-Oliveira, Karine Taís Aguiar Tavano

“…There was no statistically difference between groups in the surface roughness analysis either initially (p = 0.564) or after thermocycling (p = 0.690). …”
Get full text

In vitro mimicry of in vivo KPC mutations by ceftazidime-avibactam: phenotypes, mechanisms, genetic structure and kinetics of enzymatic hydrolysis by Siquan Shen, Chengkang Tang, Weiwei Yang, Li Ding, Renru Han, Qingyu Shi, Yan Guo, Dandan Yin, Fupin Hu

“…Four pre-therapy KPC-KP isolates (K1, K2, K3, and K4) were evaluated, all initially exhibited susceptibility to CZA and produced KPC-2. …”
Get full text

Cervical Cancer Prediction Based on Imbalanced Data Using Machine Learning Algorithms with a Variety of Sampling Methods by Mădălina Maria Muraru, Zsuzsa Simó, László Barna Iantovics

“…The average balanced accuracy for oversampling was 77.44%, compared to 62.28% for undersampling. When detecting the minority class, oversampling achieved an average score of 60.80%, while undersampling scored 41.36%. …”
Get full text

Vertical distribution of arthropod assemblages in native and exotic forests of Terceira Island (Azores, Portugal) by Sébastien Lhoumeau, Abrão Leite, Laurine Parmentier, Clémence Massard, Martha Vounatsi, Georgery Lucie, Paulo Borges

“…This study forms part of a broader research initiative designed to investigate how alterations in habitat structure influence the complexity and stability of arthropod food webs in Azorean forest habitats. …”
Get full text

Time intervals experienced between first symptom recognition and pathologic diagnosis of breast cancer in Addis Ababa, Ethiopia: a cross-sectional study by Alem Gebremariam, Adamu Addissie, Alemayehu Worku, Mathewos Assefa, Lydia E Pace, Eva Johanna Kantelhardt, Ahmedin Jemal

“…Only 8.0% were concerned about cancer initially, with most attributing their symptoms to other factors. …”
Get full text

Epidemiological characteristics of acute respiratory infectious diseases in the first year after COVID-19 pandemic in Guangdong Province, China by Ting Hu, Yali Zhuang, Lirong Zou, Zhencui Li, Yihong Li, Yan Li, Min Kang, Aiping Deng

“…The activity of influenza and Mycoplasma pneumoniae initially exhibited shifts compared to the pre-pandemic period. …”
Get full text

Feasibility of data extraction and evaluation with BeoNet-Halle: outcomes and data quality in hepatitis B and C screenings by Konstantin Moser, Konstantin Moser, Felix Bauch, Christine Brütting, Thomas Frese

“…Data completeness was evaluated by mapping the BeoNet dataset to the Medical Informatics Initiative (MII) Core Dataset.ResultsOf the potentially eligible population (32,213 patients aged ≥ 35), 10% underwent HBV and HCV screening as part of Check-Up 35. …”
Get full text

Study on Enzyme Activity and Metabolomics during Culture of Liquid Spawn of <i>Floccularia luteovirens</i> by Yanqing Ni, Qiuhong Liao, Siyuan Gou, Tongjia Shi, Wensheng Li, Rencai Feng, Zhiqiang Zhao, Xu Zhao

“…The activity of seven enzymes all followed a trend of initially increasing and then decreasing. The intra- and extracellular activity peaks of three hydrolases—amylase, protease, and cellulase—all occurred on the 20th day, except for the extracellular amylase, which peaked on the 15th day. …”
Get full text

Confirmatory mapping for lymphatic filariasis in districts previously considered nonendemic in Ghana by Joseph L. Opare, Dziedzom K. de Souza, Bright Alomatu, Ernest Mensah, Emmanuel Nyarko, Odame Asiedu, Judith Saare, Charles Brown-Davies, Irene D. Dzathor, Achille Kabore, Ernest O. Mensah

“…Treatment has therefore been initiated in the Nkoranza South and Wenchi Municipal districts. …”
Get full text

Longitudinal Metabolomics Reveals Metabolic Dysregulation Dynamics in Patients with Severe COVID-19 by Ryo Uchimido, Kenjiro Kami, Hiroyuki Yamamoto, Ryo Yokoe, Issei Tsuchiya, Yoko Nukui, Yuki Goto, Mariko Hanafusa, Takeo Fujiwara, Kenji Wakabayashi

“…The metabolite measurements were performed using capillary electrophoresis Fourier transform mass spectrometry, and we categorized the sampling time points into three time zones to align them with the disease progression: time zone 1 (T1) (the hyperacute phase, days 1–3 post-MV initiation), T2 (the acute phase, days 4–14), and T3 (the chronic phase, days 15–30). …”
Get full text