Clinical and Genetic Characteristics of Patients with Essential Tremor Who Develop Parkinson’s Disease by Gulseren Buyukserbetci, Hilmi Bolat, Ummu Serpil Sari, Gizem Turan, Ayla Solmaz Avcikurt, Figen Esmeli

“…<i>Materials and Methods:</i> We retrospectively analyzed 40 patients with a family history of ET or PD who were initially diagnosed with ET and later developed PD. …”
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Advances in the prerequisite and consequence of STING downstream signalosomes by Lu Xinliang, Li Xiaobing, Li Lili, Han Chuanhui, Li Sirui

“…Aside from recognizing pathogens through conserved motifs, these receptors also detect aberrant or misplaced self-molecules as possible signs of perturbed homeostasis. …”
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Measuring and Modeling Soil Carbon Changes on Dutch Dairy Farms by René Schils, Colin Dekker, Jouke Oenema, Gerjan Hilhorst, Jan-Paul Wagenaar, Koos Verloop

“…The current standard agronomic soil sampling program is unable to reliably detect soil carbon changes at a farm or field level. …”
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Mechanism of Nucleic Acid Sensing in Retinal Pigment Epithelium (RPE): RIG-I Mediates Type I Interferon Response in Human RPE by Joshua Schustak, Michael Twarog, Xiaoqiu Wu, Henry Y. Wu, Qian Huang, Yi Bao

“…However, how RPE cells sense stress to initiate IFN response and cause further damage to the retina are still unknown. …”
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PiRNA hsa_pir_018849 promotes the proliferation and invasion of osteosarcoma cells by regulating the stability of CCN5 mRNA by Jiale Huang, Saishuai Yang, Peng Liu, He Jiang, Zhiming Cui, Jiajia Chen

“…Methods Small RNA sequencing and qPCR were initially used to detect differentially expressed piRNAs in the MG63 osteosarcoma cell line and in osteosarcoma tissues. …”
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Clinico-epidemiological and laboratory profiles of scrub typhus in a tertiary care hospital in eastern India: an observational study by Sudeshna Mallik, Boudhayan Bhattacharjee, Swarajdeep Banik, Prantiki Halder, Sonali Das

“…Elevated liver enzymes were detected in 50% of patients, whereas chest X-rays showed pneumonitis changes in the bilateral lower zones in 60%. …”
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Validation of a deep learning–based AI system for HER2-targeted breast cancer assessment using ultrasound imaging in a clinical setting by Kathryn Malherbe

“…The sample size of 86 provided borderline statistical power (~0.74) to detect moderate effect sizes between treatment groups, considering an alpha of 0.05. …”
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Spatiotemporal variation of the association between climate dynamics and HFRS outbreaks in Eastern China during 2005-2016 and its geographic determinants. by Junyu He, George Christakos, Jiaping Wu, Bernard Cazelles, Quan Qian, Di Mu, Yong Wang, Wenwu Yin, Wenyi Zhang

“…<h4>Background</h4>Hemorrhagic fever with renal syndrome (HFRS) is a rodent-associated zoonosis caused by hantavirus. The HFRS was initially detected in northeast China in 1931, and since 1955 it has been detected in many regions of the country. …”
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Evaluation of the metabolic status and sarcopenia in the long-term period after Roux-en-Y gastric bypass and mini-gastric bypass surgery by A. G. Khitaryan, B. B. Khatsiev, A. V. Mezhunts, A. V. Sarkisyan, D. A. Melnikov, A. A. Orekhov, S. A. Adizov, A. A. Abovyan, S. P. Makarevich, S. S. Burtcev

“…Bioelectrical impedance allows to effectively detect these changes. The desired weight loss is associated with a significant decrease in skeletal muscle mass, mineral mass. …”
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Regarder au-delà des élections : l’historicité complexe de la participation politique dans la Libye contemporaine by Chiara Loschi, Chiara Pagano

“…We argue it is the lack of effective channels to promote a truly inclusive debate on post-revolutionary Libya that hinders the possibility of completing the process of revolutionizing an oppressive, exclusionary, and corrupt power system initiated by the 17 February 2011 uprising. To shed light on the current political scenario, we propose here to reconsider the political from below, and namely by looking where only disruptions to the neo-liberal model of functioning democracies have been detected so far - and thus in most manifestations referred to as 'chaos', 'statelessness' or absence of 'political culture'. …”
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Identifying nontuberculous mycobacteria from a mycobacteria growth indicator tube with nuclear magnetic resonance spectroscopy: A laboratory metabolomics analysis case report by Dr Christoffel Opperman, Dr Marwaan Rylands, Dr Sarishna Singh, Ms Aysha Amien, Mr Yonas Ghebrekristos, Prof Rob Warren, Dr Wynand Goosen

“…In this regard, NMR could potentially be used to detect the metabolomics profiles of a wide NTM spectrum, including NTM mixtures. …”
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Endovascular treatment of fusiform aneurysms of the vertebral arteries by D.V. Shchehlov, Ya.E. Kudelskyi, O.Ye. Svyrydiuk

“…Aneurysms were initially detected using neuroimaging techniques, including multislice computed tomography, magnetic resonance imaging, and magnetic resonance imaging with an angiography programme. …”
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Evaluation of Simulated Weightlessness Model of Hindlimb Unloading Miniature Pigs and Their Tissue Damage by TU Yingxin, JI Yilan, WANG Fei, YANG Dongming, WANG Dongdong, SUN Zhixin, DAI Yuexin, WANG Yanji, KAN Guanghan, WU Bin, ZHAO Deming, YANG Lifeng

“…Additionally, western blotting was employed to detect the expression levels of skeletal muscle atrophy-related proteins, including muscle-specific RING finger protein 1 (MuRf-1) and muscle atrophy F-box (MAFbx, as known as Atrogin-1), while immunohistochemistry was used to detect the expression of glial fibrillary acidic protein (GFAP), an indicator of astrocyte activation in the brain, reflecting the pathophysiological functional changes across systems. …”
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Effects of weaning and inactivated Lactobacillus helveticus supplementation on dairy calf behavioral and physiological indicators of affective state by B.K. McNeil, D.L. Renaud, M.A. Steele, L.R. Cangiano, M.F. Olmeda, C. Villot, E. Chevaux, J. Yu, L.L. Hernandez, W.S. Frizzarini, T.J. DeVries

“…Weaning resulted in fewer (d 37–41; tendency: d 36), but longer (d 38–41; tendency: d 37), lying bouts and reduced play (d 41), although no changes in lying time, MET, saliva cortisol, nor blood serotonin were detected with initiation of weaning. Supplementation of ILH was associated with less lying time throughout the study, and reduced play duration and higher salivary cortisol during weaning. …”
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Assessment of different genotyping markers and algorithms for distinguishing Plasmodium falciparum recrudescence from reinfection in Uganda by Alex Mwesigwa, Monica Golumbeanu, Sam Jones, Sara L. Cantoreggi, Benson Musinguzi, Joaniter I. Nankabirwa, Everd Maniple Bikaitwoha, Joan N Kalyango, Charles Karamagi, Mateusz Plucinski, Samuel L. Nsobya, Christian Nsanzabana, Pauline Byakika-Kibwika

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Where is the Supervirial Gas? The Supply from Hot Inflows by Manami Roy, Kung-Yi Su, Smita Mathur, Jonathan Stern

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Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia by Natasha Spottiswoode, Alexandra Tsitsiklis, Victoria T. Chu, Hoang Van Phan, Catherine DeVoe, Christina Love, Rajani Ghale, Joshua Bloomstein, Beth Shoshana Zha, Cole P. Maguire, Abigail Glascock, Aartik Sarma, Peter M. Mourani, Katrina L. Kalantar, Angela Detweiler, Norma Neff, Sidney C. Haller, COMET Consortium, Joseph L. DeRisi, David J. Erle, Carolyn M. Hendrickson, Kirsten N. Kangelaris, Matthew F. Krummel, Michael A. Matthay, Prescott G. Woodruff, Carolyn S. Calfee, Charles R. Langelier

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Targeting YBX1‐m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma by Ouwen Li, Ke An, Han Wang, Xianbin Li, Yueqin Wang, Lan Huang, Yue Du, Nuo Qin, Jiasheng Dong, Jingyao Wei, Ranran Sun, Yong Shi, Yanjia Guo, Xiangyi Sun, Ying Yang, Yun‐Gui Yang, Quancheng Kan, Xin Tian

“…Methods In this study, ferroptosis was evaluated by detecting lipid reactive oxygen species (lipid ROS), ferrous ion and 4‐hydroxynonenal (4‐HNE) in xenograft mouse model, diethylnitrosamine (DEN)‐initiated HCC model and so forth. …”
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Data Parameters From Participatory Surveillance Systems in Human, Animal, and Environmental Health From Around the Globe: Descriptive Analysis by Carrie McNeil, Nomita Divi, Charles Thomas Bargeron IV, Andrea Capobianco Dondona, Kacey C Ernst, Angela S Gupta, Olukayode Fasominu, Lucy Keatts, Terra Kelly, Onicio B Leal Neto, May O Lwin, Mvuyo Makhasi, Eric Beda Mutagahywa, Diego Montecino-Latorre, Sarah Olson, Pranav S Pandit, Daniela Paolotti, Matt C Parker, Muhammad Haiman Samad, Kara Sewalk, Anita Sheldenkar, Lertrak Srikitjakarn, Channé Suy Lan, Michael Wilkes, Terdsak Yano, Mark Smolinski

“… BackgroundEmerging pathogens and zoonotic spillover highlight the need for One Health surveillance to detect outbreaks as early as possible. Participatory surveillance empowers communities to collect data at the source on the health of animals, people, and the environment. …”
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Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning. by Elizabeth A Cromwell, Joshua C P Osborne, Thomas R Unnasch, Maria-Gloria Basáñez, Katherine M Gass, Kira A Barbre, Elex Hill, Kimberly B Johnson, Katie M Donkers, Shreya Shirude, Chris A Schmidt, Victor Adekanmbi, Olatunji O Adetokunboh, Mohsen Afarideh, Ehsan Ahmadpour, Muktar Beshir Ahmed, Temesgen Yihunie Akalu, Ziyad Al-Aly, Fahad Mashhour Alanezi, Turki M Alanzi, Vahid Alipour, Catalina Liliana Andrei, Fereshteh Ansari, Mustafa Geleto Ansha, Davood Anvari, Seth Christopher Yaw Appiah, Jalal Arabloo, Benjamin F Arnold, Marcel Ausloos, Martin Amogre Ayanore, Atif Amin Baig, Maciej Banach, Aleksandra Barac, Till Winfried Bärnighausen, Mohsen Bayati, Krittika Bhattacharyya, Zulfiqar A Bhutta, Sadia Bibi, Ali Bijani, Somayeh Bohlouli, Mahdi Bohluli, Oliver J Brady, Nicola Luigi Bragazzi, Zahid A Butt, Felix Carvalho, Souranshu Chatterjee, Vijay Kumar Chattu, Soosanna Kumary Chattu, Natalie Maria Cormier, Saad M A Dahlawi, Giovanni Damiani, Farah Daoud, Aso Mohammad Darwesh, Ahmad Daryani, Kebede Deribe, Samath Dhamminda Dharmaratne, Daniel Diaz, Hoa Thi Do, Maysaa El Sayed Zaki, Maha El Tantawi, Demelash Abewa Elemineh, Anwar Faraj, Majid Fasihi Harandi, Yousef Fatahi, Valery L Feigin, Eduarda Fernandes, Nataliya A Foigt, Masoud Foroutan, Richard Charles Franklin, Mohammed Ibrahim Mohialdeen Gubari, Davide Guido, Yuming Guo, Arvin Haj-Mirzaian, Kanaan Hamagharib Abdullah, Samer Hamidi, Claudiu Herteliu, Hagos Degefa de Hidru, Tarig B Higazi, Naznin Hossain, Mehdi Hosseinzadeh, Mowafa Househ, Olayinka Stephen Ilesanmi, Milena D Ilic, Irena M Ilic, Usman Iqbal, Seyed Sina Naghibi Irvani, Ravi Prakash Jha, Farahnaz Joukar, Jacek Jerzy Jozwiak, Zubair Kabir, Leila R Kalankesh, Rohollah Kalhor, Behzad Karami Matin, Salah Eddin Karimi, Amir Kasaeian, Taras Kavetskyy, Gbenga A Kayode, Ali Kazemi Karyani, Abraham Getachew Kelbore, Maryam Keramati, Rovshan Khalilov, Ejaz Ahmad Khan, Md Nuruzzaman Nuruzzaman Khan, Khaled Khatab, Mona M Khater, Neda Kianipour, Kelemu Tilahun Kibret, Yun Jin Kim, Soewarta Kosen, Kris J Krohn, Dian Kusuma, Carlo La Vecchia, Van Charles Lansingh, Paul H Lee, Kate E LeGrand, Shanshan Li, Joshua Longbottom, Hassan Magdy Abd El Razek, Muhammed Magdy Abd El Razek, Afshin Maleki, Abdullah A Mamun, Ali Manafi, Navid Manafi, Mohammad Ali Mansournia, Francisco Rogerlândio Martins-Melo, Mohsen Mazidi, Colm McAlinden, Birhanu Geta Meharie, Walter Mendoza, Endalkachew Worku Mengesha, Desalegn Tadese Mengistu, Seid Tiku Mereta, Tomislav Mestrovic, Ted R Miller, Mohammad Miri, Masoud Moghadaszadeh, Abdollah Mohammadian-Hafshejani, Reza Mohammadpourhodki, Shafiu Mohammed, Salahuddin Mohammed, Masoud Moradi, Rahmatollah Moradzadeh, Paula Moraga, Jonathan F Mosser, Mehdi Naderi, Ahamarshan Jayaraman Nagarajan, Gurudatta Naik, Ionut Negoi, Cuong Tat Nguyen, Huong Lan Thi Nguyen, Trang Huyen Nguyen, Rajan Nikbakhsh, Bogdan Oancea, Tinuke O Olagunju, Andrew T Olagunju, Ahmed Omar Bali, Obinna E Onwujekwe, Adrian Pana, Hadi Pourjafar, Fakher Rahim, Mohammad Hifz Ur Rahman, Priya Rathi, Salman Rawaf, David Laith Rawaf, Reza Rawassizadeh, Serge Resnikoff, Melese Abate Reta, Aziz Rezapour, Enrico Rubagotti, Salvatore Rubino, Ehsan Sadeghi, Abedin Saghafipour, S Mohammad Sajadi, Abdallah M Samy, Rodrigo Sarmiento-Suárez, Monika Sawhney, Megan F Schipp, Amira A Shaheen, Masood Ali Shaikh, Morteza Shamsizadeh, Kiomars Sharafi, Aziz Sheikh, B Suresh Kumar Shetty, B Suresh Kumar Shetty, Jae Il Shin, K M Shivakumar, Biagio Simonetti, Jasvinder A Singh, Eirini Skiadaresi, Amin Soheili, Shahin Soltani, Emma Elizabeth Spurlock, Mu'awiyyah Babale Sufiyan, Takahiro Tabuchi, Leili Tapak, Robert L Thompson, Alan J Thomson, Eugenio Traini, Bach Xuan Tran, Irfan Ullah, Saif Ullah, Chigozie Jesse Uneke, Bhaskaran Unnikrishnan, Olalekan A Uthman, Natalie V S Vinkeles Melchers, Francesco S Violante, Haileab Fekadu Wolde, Tewodros Eshete Wonde, Tomohide Yamada, Sanni Yaya, Vahid Yazdi-Feyzabadi, Paul Yip, Naohiro Yonemoto, Hebat-Allah Salah A Yousof, Chuanhua Yu, Yong Yu, Hasan Yusefzadeh, Leila Zaki, Sojib Bin Zaman, Maryam Zamanian, Zhi-Jiang Zhang, Yunquan Zhang, Arash Ziapour, Simon I Hay, David M Pigott

“…National onchocerciasis elimination programmes may wish to consider prioritising these IUs for mapping surveys as human resources, laboratory capacity, and programmatic schedules may constrain survey implementation, and possibly delaying MDA initiation in areas that would ultimately qualify.…”
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