Genomic context determines the effect of DNA methylation on gene expression in the gut epithelium of Atlantic salmon (Salmo salar) by Aikaterini Katirtzoglou, Søren B. Hansen, Harald Sveier, Michael D. Martin, Jaelle C. Brealey, Morten T. Limborg

“…Assuming epigenetic signals might be pronounced between distinctive phenotypes, we compared large and small fish, finding 22 significant associations between 22 differentially methylated regions and 21 genes. We did not detect significant methylation differences between large and small fish. …”
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Treatment of chronic hepatitis B: options, monitoring, special cases and adverse effects by Mateusz Litwin Litwin, Agnieszka Mikosińska, Jakub Parys, Patrycja Kałuziak, Aleksandra Witek, Martyna Kaźmierczak, Stanisław Jesionek, Marta Jajczak, Maciej Mossakowski

“…The paper also describes therapeutic possibilities in special cases, such as pregnancy, liver transplantation, and the initiation of immunosuppressive therapy. Attention is also given to the potential adverse effects of pharmacotherapy. …”
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A Radio Flaring, Chromospherically Inactive K Dwarf by Dale A. Frail, Scott D. Hyman, Michele L. Silverstein, Emil Polisensky, Evangelia Tremou, Simona Giacintucci, Hodari-Sadiki Hubbard-James, Jacinda Byam, Steve B. Howell, Robert F. Wilson, Matthew Lastovka, Tracy E. Clarke, Namir E. Kassim

“…We report on an unusual radio source (J180526−292953), initially identified as a steep spectrum, polarized point source toward the Galactic bulge and found to coincide with the nearby K dwarf HD 317101A. …”
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The long-term outcomes of metachronous tumors for non-small cell lung cancer by Celalettin Kocaturk, Cem Emrah Kalafat, Celal Bugra Sezen, Mustafa Vedat Dogru, Levent Cansever, Muzaffer Metin, Mehmet Ali Bedirhan

“…Conclusions: New lung tumors may be detected during follow-up of lung cancer patients who have been definitively treated. …”
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Evaluation of Stemona collinsiae root extracts for topical cockroach control: adulticidal, nymphicidal, and chemical distribution analysis by Aurapa Sakulpanich, Anon Phayakkaphon, Korawan Ounklong, Jinnaphat Sommanat, Yudthana Samung, Raweewan Srisawat, Jiraporn Ruangsittichai

“…In this research, contact toxicity of hexane, dichloromethane, ethanol, and water extracts was repeatedly tested on final-instar nymphs and adult Periplaneta americana using a topical application method and the penetration and distribution of didehydrostemofoline were detected at each of the specified times using MALDI-IMS and HPLC. …”
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Seroprevalence of CMV infection in patients with active ulcerative colitis and underlying factors of pathogenicity by Farahnaz Joukar, Mohammad Almasi, Narges Eslami, Niloofar Faraji, Kurosh Askari, Ghazale Ghorbani, Navid Yusefi, Fariborz Mansour-Ghanaei

“…Following this, polymerase chain reaction (PCR) was employed to detect CMV DNA in plasma samples using specific primers. …”
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Efficacy and Safety of Intravenous Tenecteplase Before Endovascular Thrombectomy for Acute Ischemic Stroke: The Multicenter, Randomized, BRIDGE‐TNK Trial Protocol by Zhongming Qiu, Fengli Li, Dongjing Xie, Guangxiong Yuan, Thanh N. Nguyen, Kai Zhou, Raul G. Nogueira, Jeffrey L. Saver, Bruce C.V. Campbell, Gregory W. Albers, Hongfei Sang, Linyu Li, Yan Tian, Zhaoyou Meng, Duolao Wang, Wenjie Zi, Qingwu Yang

“…Background Six randomized trials have not detected a difference between intravenous alteplase plus endovascular thrombectomy and endovascular thrombectomy alone in stroke. …”
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Targeting cGAS-STING: modulating the immune landscape of hepatic diseases by Feng Xue, Feng Xue, Yong-Kang Liu, Yong-Kang Liu, Xiao-Ying Chen, Shan-Shan Chen, Xiang-Rong Yu, Hua-Wen Li, Li-Gong Lu, Li-Gong Lu, Mu-He Chen, Mu-He Chen

“…The cGAS-STING pathway, a critical part of the innate immune system, plays a crucial role in detecting cytoplasmic DNA and initiating immune responses, including autoimmune inflammation and antitumor immunity. …”
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Long‐Term Treatment With Subcutaneous Treprostinil in Patients With Severe Inoperable Chronic Thromboembolic Pulmonary Hypertension in the Multimodal Therapy Era (Data From CTREPH... by Pavel Jansa, Roela Sadushi‐Kolici, Nika Skoro‐Sajer, Grzegorz Kopec, Iveta Simkova, Regina Steringer‐Mascherbauer, Barbara Salobir, Jaroslav Lindner, Irene M. Lang

“…No new safety signal was detected. Evaluated clinical outcomes show sustained benefit from long‐term treprostinil treatment. …”
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A Unique Combination of Mn2+ and Aluminum Adjuvant Acted the Synergistic Effect by Yuwei Cen, Shujie Chen, Shuyu Wei, Shuangshuang Wu, Mingyang Tao, Youxi Fu, Yuncheng Wang, Jing Chen, Yixuan Ma, Hongyan Liu, Baifen Song, Jinzhu Ma, Beiyan Wang, Yudong Cui

“…Here, we described a novel combination of Mn2+ plus aluminum hydroxide (AH) adjuvant that significantly exhibited the synergistic immune effect. Methodology. Initially, IsdB3 proteins as the immune-dominant fragment of IsdB proteins derived from Staphylococcus aureus (S. aureus) were prepared. …”
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Distribution and prevalence of Baylisascaris in domestic dogs in the United States and Canada, 2017–2023 by Håkon Jones, Pablo D. Jimenez Castro, Wade Burton, Caroline Sobotyk, Guilherme G. Verocai, Yoko Nagamori, Zephran Warren, Antoinette Marsh, Cassan Pulaski, Heather S.D. Walden, Ashley M. Mitchell, Brian H. Herrin, Jeba R.J. Jesudoss Chelladurai, Michael J. Yabsley

“…Baylisascaris eggs were detected in 2927 of 61,129,486 (0.0048 %) fecal samples. …”
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Fluorescein-distribution in confocal laser endomicroscopy allows for discrimination between primary brain tumours and metastases by Maria C. Brielmaier, Maria C. Brielmaier, Johannes Reifenrath, Franziska Ganster, Nicolas Pensel, Jens Gempt, Jens Gempt, Bernhard Meyer, Jürgen Schlegel, Arthur Wagner

“…In gliomas and meningiomas, SF could only be detected in 14.3% and 16.1% of images per case, while in carcinoma metastases, SF would accumulate in 68.1% of images per case.DiscussionThe concordant results from in vitro, ex vivo and in vivo investigations could show that the cellular accumulation of the staining agent SF varies depending on the tumour entity. …”
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STING is significantly increased in high-grade glioma with high risk of recurrence by Meishi Zhong, Manmei Long, Chenjie Han, Saiyan Ji, Qingyuan Yang

“…A total of 126 surgical tissues from patients initially diagnosed with glioma were included. The genetic alterations were tested using the targeted next-generation sequencing technique. …”
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Early posttranscriptional response to tetracycline exposure in a gram-negative soil bacterium reveals unexpected attenuation mechanism of a DUF1127 gene by Jennifer A. F. Kothe, Till Sauerwein, Theresa Dietz, Robina Scheuer, Muhammad Elhossary, Susanne Barth-Weber, Jan Wähling, Konrad U. Förstner, Elena Evguenieva-Hackenberg

“…The accessibility is blocked either by impaired translation initiation or, in the absence of ribosome binding, by base-pairing between the RBS and the C-rich codons. …”
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Microorganisms associated with bacterial vaginosis: diversity and clinical and diagnostic significance by N. M. Voropaeva, N. L. Belkova, J. M. Nemchenko, E. V. Grigorova, I. N. Danusevich

“…According to the opinion of some authors, initially, the main role of BV in the pathogenesis was assigned to the species G. vaginalis. …”
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Continuous digital cough monitoring during 6-month pulmonary tuberculosis treatment by Mihaja Raberahona, Alexandra Zimmer, Rivonirina Andry Rakotoarivelo, Patrick Andriniaina Randrianarisoa, Garcia Rambeloson, Etienne Rakotomijoro, Christophe Elody Andry, Haingonirina Anique Razafindrakoto, Dera Andriantahiana, Mamy Jean de Dieu Randria, Niaina Rakotosamimanana, Simon Grandjean Lapierre

“…Methods We prospectively enrolled PTB adult participants upon treatment initiation. Participants’ coughs were continuously monitored during 6 months with a smartphone loaded with an app able to detect cough by using an AI algorithm. …”
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Probable airborne transmission of Burkholderia pseudomallei causing an urban outbreak of melioidosis during typhoon season in Hong Kong, China by Wing-Gi Wu, Marcus Ho-Hin Shum, Ivan Tak-Fai Wong, Kelvin Keru Lu, Lam-Kwong Lee, Jake Siu-Lun Leung, Hiu-Yin Lao, Annie Wing-Tung Lee, Pak-Ting Hau, Chloe Toi-Mei Chan, Harmen Fung-Tin Wong, Sharon Ka-Yee Fung, Sally Choi-Ying Wong, Iain Chi-Fung Ng, Timothy Ting-Leung Ng, Ning Chow, Alex Yat-Man Ho, Mei Fan Hung, Franklin Wang-Ngai Chow, Maureen Mo-Lin Wong, Wing-Kin To, Tommy Tsan-Yuk Lam, Kristine Shik Luk, Gilman Kit-Hang Siu

“…Clinicians should be aware of melioidosis during typhoon season and initiate appropriate investigation and treatment for patients with compatible symptoms.…”
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Emergency Identification of Endotracheal Tube Tip via Ultrasonography Used by Trained Nurse in the Neonatal Intensive Care Unit (NICU) by Athanasia Voulgaridou, Savas Deftereos, Pelagia Chloropoulou, Konstantina Bekiaridou, Emmanouela Tsouvala, Rozita Meziridou, Soultana Foutzitzi, Christos Kaselas, Xenophon Sinopidis, Elpis Mantadakis, Katerina Kambouri

“…Ultrasonography (US) has emerged as a valuable tool to detect ETT positioning, competing with traditional methods. …”
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Protocol for a parallel-group, superiority randomized controlled trial of the PulsePoint mobile application to increase bystander resuscitation in out-of-hospital cardiac arrest by Steven C. Brooks, John M. Tallon, Sandra Jenneson, Ashish R. Panchal, Robert Grierson, Laurie J. Morrison, Damon C. Scales, Andrew Day, Lindsay O’Donnell, Randy S. Wax, Helen Connolly, Jennie Helmer, Heidi Corneil, Jim Christenson

“…Despite public awareness campaigns, widespread cardiopulmonary resuscitation (CPR) training initiatives, and deployment of public access defibrillators, potentially life-saving bystander intervention occurs inconsistently. …”
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Evidence of bacterial imprints in different types of non-struvite kidney stones by Felix Grases, Antonia Costa-Bauzá, Francesca Julià, Bernat Isern, Jordi Guimerà, José Luis Bauzá-Quetglas, Valentí Tubau, Enrique Pieras

“…When bacterial imprints were detected, biochemical and bacteriological analysis of the patient’s urine was performed. …”
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