m6A-Methylated NUTM2B-AS1 Promotes Hepatocellular Carcinoma Stemness Feature via Epigenetically Activating BMPR1A Transcription by Li W, Zeng M, Ning Y, Lu R, Wei Y, Xu Z, Wei H, Pu J

“…As the most abundant modification in RNA, N6-methyladenosine (m6A) has been reported to be involved in HCC initiation and progression. However, whether m6A has oncofetal characteristics remains unknown.Methods: Gene expression in HCC tissues and cells was detected using qPCR. …”
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Genetic surveillance shows spread of ACT resistance during period of malaria decline in Vietnam (2018-2020) by Johanna Helena Kattenberg, Mathijs Mutsaers, Van Hong Nguyen, Thi Hong Ngoc Nguyen, Arlette Umugwaneza, Maria Lara-Escandell, Xuan Xa Nguyen, Thi Huong Binh Nguyen, Anna Rosanas-Urgell

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Surgical stress response following hip arthroplasty regarding choice of anesthesia and postoperative analgesia by Kendrišić Mirjana, Šurbatović Maja, Đorđević Dragan, Jevđić Jasna

“…The highest serum insulin levels were detected 4 h postoperatively in the CNB and PNB group, while the lowest were in the GAM group (F = 5.811; p < 0.05). …”
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Vitamins, carotenoids and microelements in prostate carcinogenesis by P. V. Glybochko, E. G. Zezerov, D. V. Butnaru, V. B. Spirichev, N. A. Beketova, G. K. Barashkov, V. A. Varshavsky, Yu. G. Alyaev, S. E. Severin, E. V. Osipov, O. G. Pereverzeva, E. A. Bezrukov, A. Z. Vinarov

“…The aforementioned changes associated with the mechanism of prostate carcinogenesis are already detected in patients with HGPIN (precancer) with no further progression in patients with developed CaP.…”
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Early point-of-care focused echocardiographic asystole as a predictive factor for absence of return of spontaneous circulatory in out-of-hospital cardiac arrests: a study protocol... by François Javaudin, Philippe Pes, Emmanuel Montassier, Arnaud Legrand, Aline Ordureau, Christelle Volteau, Idriss Arnaudet, Philippe Le Conte

“…The physician will assess detectable motion within the heart and reversible causes of OHCA. …”
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Multiple angiosarcomas of both breasts: a case report by Ryota Matsuda, Michiyo Saimura, Keisei Anan, Kento Katsuyama, Yuki Tahara, Kanako Kurata, Kohei Horioka, Mitsuhiro Nakamoto, Kenichiro Koga, Shoshu Mitsuyama, Eiichi Sato, Shinichi Wakamatsu, Sadafumi Tamiya

“…We herein report a rare case of multiple angiosarcomas detected concurrently in both breasts. Case presentation A 49-year-old woman visited a doctor after noticing a lump in her right breast. …”
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Modeling Hot, Anisotropic Ion Beams in the Solar Wind Motivated by the Parker Solar Probe Observations near Perihelia by Leon Ofman, Yogesh, Scott A. Boardsen, Parisa Mostafavi, Lan K. Jian, Viacheslav M. Sadykov, Kristopher Klein, Mihailo Martinović

“…The models are initialized with ion VDFs motivated by the observational parameters. …”
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ROS-Drp1-mitophagy feedback loop regulates myogenic differentiation via actin cytoskeleton remodeling-mediated MRTF-A/SRF axis by Aiwen Jiang, Luyao Wang, Xinyu Liu, Jialong Li, Haifei Wang, Shenglong Wu, Wenbin Bao

“…Background Mitochondrial division is one of the main characteristics for the initiation of myogenic differentiation. However, the role and mechanism of Dynamin-related protein 1 (Drp1), the most important protein that regulates mitochondrial fission in mammals, in regulating myogenic differentiation are not well understood.Methods Drp1 siRNAs were transfected to C2C12 cells, or AAV9-shDrp1 were injected to C57BL/6J mice to knockdown Drp1 expression. …”
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Toxoplasma gondii infection in aborted women and sheep in the governorates of El-Beheira and Alexandria, Egypt: A sero-immunological and molecular study by Haitham Elaadli, Nagwa .I. Toaleb, Dina Aboelsoued, Emad B. Ata, Nehal M. Khairy, Raafat M. Shaapan

“…An indirect ELISA was performed to detect the prevalence in aborted women and sheep. …”
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Cytogenetic aberration in mixed-phenotype acute leukemia in children: A single-center retrospective review by Tsung-Yen Chang, Shih-Hsiang Chen, Tang-Her Jaing, Shu-Ho Yang, Yu-Chuan Wen, Chao-Ping Yang, Iou-Jih Hung

“…The b3a2 (p210) and e1a2 (p190) BCR/ABL fusion transcripts were detected in 1 patient with B/myeloid MPAL. Regarding the morphology, all patients were initially diagnosed as acute lymphoblastic leukemia, but no morphological characteristics or cytogenetic aberration was particularly predictive of an MPAL. …”
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Deciphering the stromal molecular landscape: the correlation between p16 and α-SMA in epithelial ovarian cancer by Marta Caretto, Angiolo Gadducci, Sabina Pistolesi, Diletta Mattiussi Tome, Giuseppe Nicolò Fanelli, Antonio Giuseppe Naccarato, Tommaso Simoncini

“…Abstract Introduction The tumor microenvironment (TME) plays an essential role in promoting cancer initiation, progression and metastasis. Cancer-associated fibroblasts (CAFs) are a major constituent of the TME, but universal CAFs’ markers have not yet been identified. …”
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Vital role of autophagy flux inhibition of placental trophoblast cells in pregnancy disorders induced by HEV infection by Yifei Yang, Bo Liu, Jijing Tian, Xuepeng Teng, Tianlong Liu

“…All processes of autophagic flux, which include the initiation, development, and maturation three stages, were suppressed in JEG-3 cells after HEV infection. …”
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Cisplatin intra-arterial chemotherapy for recurrent maxillary gingival cancer and metastatic lymph nodes without radiation or surgery: A case report by Akemi Ohtani, MD, Masato Saito, MD, PhD, Naoki Hirokawa, MD, PhD, Hiroki Okuda, MD, PhD, Hiroki Sato, MD, Kenichiro Nitta, MD, Shoh Mafune, MD, Akihiro Miyazaki, DDS, PhD, Hironari Dehari, DDS, PhD, Masanori Someya, MD, PhD

“…His recurrent lesions were located on the left maxillary bone, and a metastatic cervical lymph node was detected. We approached the feeder of the locoregional recurrence site using Seldinger's technique and repeated the cisplatin intra-arterial chemotherapy 5 times. …”
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The novelty of profilin 2 in regulating pyruvate kinase M2 nuclear translocation and promoting tumor angiogenesis in lung adenocarcinoma by Xiaohui Du, Chi Ma, Yingyan Wang, Mingxin Xu, Yanbin Kuang, Mengyun Li, Shuang Wen, Peipei He, Hui Zhao, Qi Wang

“…Methods Immunohistochemistry and western blotting were used to detected the expression levels of related proteins in tissue or lung cancer cells. …”
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The Complete Mitochondrial Genome of <i>Thymus mongolicus</i> and Its Phylogenetic Relationship with Lamiaceae Species by Na Na, Zinian Wu, Zhiyong Wang, Yanting Yang, Chunyu Tian, Lin Zhu, Taiyou Ou, Xiaofei Chen, Hongyan Xia, Zhiyong Li

“…With the exception of nad4L, which uses ACG/ATG as an initiation codon, all other genes begin with the ATG start codon. …”
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Deferential nephrotoxicity effect of lanthanum oxide nanoparticle responses to concentration and time in vivo by Nouf M. Alyami, Ghufran A. Almuhaini, Hussah Alobaid, Saleh Maodaa, Noura M. Alshiban, Zainab Ali Alnakhli, Faten Jamal Alashkar, Khalid Elfaki Ibrahim, Saeed Alqahtani, Rafa Almeer, Hanadi M. Alyami, Saud Alarifi

“…In contrast, higher doses initially caused inflammation that subsided over time. …”
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Clinical and Pathological Features of Flexural Deformities Associated with Myopathies in Foals by Maria Pia Pasolini, Luigi Auletta, Davide De Biase, Emanuela Vaccaro, Chiara Del Prete, Chiara Montano, Mariaelena de Chiara, Evaristo Di Napoli, Orlando Paciello, Giuseppe Piegari

“…Therapy is typically initiated without a precise diagnosis, and the etiopathogenesis often remains unknown. …”
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Estimation of Ukraine’s foreign trade structure in order to determine the areas of export potential by Nadiya Dekhtyar, Oksana Mazorenko, Maksym Serpukhov

“…Nevertheless, new potential exporting destinations may be found, precisely because of the detected imbalances.…”
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Development and validation of a clinical prediction model for Clostridioides difficile associated diarrhea by Ruiying Zheng, Hewei Luan, Jun Zhou, Zhixin Shi, Xin Hong, Lei Huang, Genyan Liu

“…Clinicians can use the nomogram to initially assess the likelihood of CDAD when the patient suffers diarrhea, to ensure timely specific laboratory tests, and appropriate diagnostic and treatment measures. …”
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Metal-polluted Population III Galaxies and How to Find Them by Elka Rusta, Stefania Salvadori, Viola Gelli, Daniel Schaerer, Alessandro Marconi, Ioanna Koutsouridou, Stefano Carniani

“…In this phase, PopIII galaxies have [O III ]/H β  ≈ 1, which opens the pool of candidates to more easily detectable sources. We predict that the high He II emission of PopIII galaxies can last up to ≈20 Myr and that it is partly maintained in the “hybrid” phase, when PopIII and Population II stars coexist in the host galaxy. …”
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