A comprehensive integrated disease management program for phenylketonuria (IDMP-PKU) from Türkiye: rationale, design and patient characteristics by Mehmet Cihan Balci, Deniz Kor, Yilmaz Yildiz, Meryem Karaca, Fatma Derya Bulut, Ayca Burcu Kahraman, Alihan Yesil, Ezgi Burgac, Kismet Ciki, Arzu Selamioglu, Burcu Koseci, Asli Durmus, Irem Kaplan, Esra Kara, Halise Neslihan Mungan, Serap Sivri, Gulden Fatma Gokcay, Aysegul Tokatli, Mubeccel Demirkol, Turgay Coskun, Imran Ozalp

“…Diagnosis and prompt initiation of appropriate treatment shortly after birth are important for achieving optimal outcomes in phenylketonuria. …”
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eDNA Metabarcoding Reveals the Depth-Structured Variation of Coral Reef Fish by Jinfa Zhao, Lin Lin, Yong Liu, Teng Wang, Yu Liu, Yayuan Xiao, Jianzhong Shen, Hongyu Xie, Hai Huang, Qiuying Han

“…The results indicated that the eDNA technology detected a total of 213 amplicon sequence variants (ASVs), including 33 species that were not identified using traditional methods. …”
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Clinical and epidemiologic characteristics of dengue and other etiologic agents among patients with acute febrile illness, Puerto Rico, 2012-2015. by Kay M Tomashek, Olga D Lorenzi, Doris A Andújar-Pérez, Brenda C Torres-Velásquez, Elizabeth A Hunsperger, Jorge Luis Munoz-Jordan, Janice Perez-Padilla, Aidsa Rivera, Gladys E Gonzalez-Zeno, Tyler M Sharp, Renee L Galloway, Mindy Glass Elrod, Demetrius L Mathis, M Steven Oberste, W Allan Nix, Elizabeth Henderson, Jennifer McQuiston, Joseph Singleton, Cecilia Kato, Carlos García Gubern, William Santiago-Rivera, Jesús Cruz-Correa, Robert Muns-Sosa, Juan D Ortiz-Rivera, Gerson Jiménez, Ivonne E Galarza, Kalanthe Horiuchi, Harold S Margolis, Luisa I Alvarado

“…Of 8,996 participants enrolled from May 7, 2012 through May 6, 2015, more than half (54.8%, 4,930) had a pathogen detected. Pathogens most frequently detected were CHIKV (1,635, 18.2%), FLU A/B (1,074, 11.9%), DENV 1-4 (970, 10.8%), and ORV (904, 10.3%). …”
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The use of heart rate variability, oxygen saturation, and anthropometric data with machine learning to predict the presence and severity of obstructive sleep apnea by Rafael Rodrigues dos Santos, Matheo Bellini Marumo, Alan Luiz Eckeli, Helio Cesar Salgado, Luiz Eduardo Virgílio Silva, Renato Tinós, Rubens Fazan

“…Our findings have the potential to contribute to the development of rapid screening tools aimed at assisting individuals affected by this condition, to expedite diagnosis and initiate timely treatment.…”
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Bridge Deformation Prediction Using KCC-LSTM With InSAR Time Series Data by Zechao Bai, Chang Shen, Yanping Wang, Yun Lin, Yang Li, Wenjie Shen

“…Therefore, accurately predicting bridge deformation is essential for analyzing its causes and detecting potential safety hazards in a timely manner. …”
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Volumetric evolution of supraglacial lakes in southwestern Greenland using ICESat-2 and Sentinel-2 by T. Feng, T. Feng, X. Ma, X. Ma, X. Liu, X. Liu, X. Liu

“…Second, the depth of SGLs along the ICESat-2 profile is detected using the kernel density analysis method. …”
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Molecular mechanism of the impact of environmental stress on plant flowering by ZHANG Jishun, ZHANG Xiaolian, WANG Rengang, XIE Shengdong, WANG Yi, REN Xueliang

“…Under the control of a complex genetic network, plants detect and integrate external (such as photoperiod and temperature) and/or endogenous (such as age and hormone level) signals to induce or suppress flowering. …”
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Postoperative acute multiple organ failure after hepatectomy in a Nigerian male with sickle cell trait: a case report by Toshimitsu Iwasaki, Satoshi Nara, Yuuki Nishimura, Hiroki Ueda, Yoji Kishi, Minoru Esaki, Kazuaki Shimada, Nobuyoshi Hiraoka

“…The patient’s renal and respiratory functions also deteriorated; therefore, continuous hemodiafiltration and plasma exchange were initiated under mechanical ventilation. Whole-body contrast-enhanced CT showed no apparent ischemia of the remnant liver, but diffuse cerebral infarction was detected. …”
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Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations by D. E. Ivanoshchuk, S. V. Mikhailova, O. G. Fenkova, E. V. Shakhtshneider, A. Z. Fursova, I. V. Bychkov, M. I. Voevoda

“…Consequently, in children with signs of increased intraocular pressure, molecular genetic analysis of the CYP1B1 gene is advisable for early diagnosis and timely initiation of PCG therapy.…”
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ATYPICAL HEMOLYTIC UREMIC SYNDROME DIAGNOSIS AND TREATMENT by Atakan Turgutkaya

“…Stool sampling should be done in individuals with diarrhea to detect Shiga toxin and/or microorganisms that produce Shiga toxin. …”
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Real-Life Diagnostic Accuracy and Clinical Utility of Hepatitis B Virus (HBV) Nucleic Acid Testing Using the GeneXpert Point-of-Care Test System from Fresh Plasma and Dry Blood Spo... by Amie Ceesay, Sainabou Drammeh, Gibril Ndow, Alpha Omar A. Jallow, Haddy Nyang, Baboucarr Bittaye, Francis S. Mendy, Ousman Secka, Umberto D’Alessandro, Yusuke Shimakawa, Erwan Vo-Quang, Barbara Testoni, Mark Thursz, Maud Lemoine, Isabelle Chemin

“…The GeneXpert HBV test displayed excellent diagnostic accuracy by detecting HBV viremia in less than 10 IU/mL.…”
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Tuning the Legacy Survey of Space and Time Observing Strategy for Solar System Science: Incremental Templates in Year 1 by James E. Robinson, Megan E. Schwamb, R. Lynne Jones, Mario Jurić, Peter Yoachim, Bryce T. Bolin, Colin O. Chandler, Steven R. Chesley, Grigori Fedorets, Wesley C. Fraser, Sarah Greenstreet, Henry H. Hsieh, Lauren J. McGinley, Stephanie R. Merritt, Cyrielle Opitom, John K. Parejko

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Trans anal drainage tube use for preventing anastomotic leakage af ter laparoscopic low anterior resection in patients with rec tal cancer a randomized clinical trial by Li Shaotang

“…[Results] In total, 576 patients were initially enrolled in this study; 16 of these patients were excluded. …”
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Bounce effect or local recurrence after low-dose-rate brachytherapy of the prostate? When prostate-specific membrane antigen positron emission tomography–computed tomography is fal... by Tamas Rozsos, Daniel S. Engeler, Hans-Peter Schmid, Christoph Schwab

“…This consideration is vital when evaluating a patient with a rising prostate-specific antigen level after brachytherapy, to avoid premature initiation of salvage therapy.…”
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Associations of serum uric acid trajectories with hypertension risk: exploring differences between age groups by Mao Li, Bin Yu, Jia Pan, Chaohui Dong, Honglian Zeng, Shujuan Yang

“…Incident hypertension was defined as newly detected blood pressure ≥140/90 mmHg, or the initiation of anti-hypertensive medication. …”
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Accurate and robust prediction of Amyloid-β brain deposition from plasma biomarkers and clinical information using machine learning by Jiayuan Xu, Andrew J. Doig, Sofia Michopoulou, Sofia Michopoulou, Petroula Proitsi, Petroula Proitsi, Fumie Costen, The Alzheimer's disease neuroimaging initiative

“…The development of a low-cost method to detect Aβ deposition in the brain, as an alternative to PET, would therefore be of great value. …”
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The Trendermarsch sunken in the Wadden Sea (North Frisia, Germany) – reconstructing a drowned medieval cultural landscape with geoarchaeological and geophysical investigations by A. Reiß, H. Hadler, D. Wilken, B. S. Majchczack, R. Blankenfeldt, S. Bäumler, U. Ickerodt, S. Klooß, T. Willershäuser, W. Rabbel, A. Vött

“…Guided by the evaluation and georeferencing of historical sources and embankment plans, the geophysical prospection was initially carried out in equidistant search grids and then intensified in areas of detected anomalies. …”
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A cross‐sectional study evaluating the frequency of HIV drug resistance mutations among individuals diagnosed with HIV‐1 in tenofovir disoproxil fumarate‐based pre‐exposure prophyl... by Urvi M. Parikh, Lauren D. Kudrick, Lisa Levy, Everline Bosek, Bhavna H. Chohan, Irene Mukui, Sarah Masyuko, Nonhlanhla Ndlovu, Imelda Mahaka, Owen Mugurungi, Gertrude Ncube, Anita Hettema, Sindy N. Matse, Saiqa Mullick, Carole L. Wallis, Amy L. Heaps, Kerri J. Penrose, Kevin D. McCormick, Lubbe Wiesner, Peter L. Anderson, Jill M. Peterson, Connie Celum, Barbra A. Richardson, Delivette Castor, Shannon Allen, Kristine Torjesen, John W. Mellors, Global Evaluation of Microbicide Sensitivity (GEMS) Project

“…Thirty‐four seroconversions occurred within 30 days of PrEP initiation. Tenofovir‐diphosphate levels were consistent with moderate to high levels (≥350 femtomoles per punch) in 53% (120 of 226) individuals with drug‐level data. …”
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Bioremediation of Persistent Organic Pollutant—Oxybenzone with <i>Pleurotus djamor</i> by Agata Kryczyk-Poprawa, Wojciech Baran, Katarzyna Sułkowska-Ziaja, Katarzyna Kała, Ewa Adamek, Małgorzata Król, Adrián Sánchez-Hidalgo, Bożena Muszyńska

“…Oxybenzone, a common sunscreen ingredient, has been widely detected in various environmental matrices, posing significant ecological and health risks. …”
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The role of vascularity and the fibrovascular interface in interstitial lung diseases by Jana Dietrich, Alice Kang, Birger Tielemans, Stijn E. Verleden, Hassan Khalil, Florian Länger, Philipp Bruners, Steven J. Mentzer, Tobias Welte, Michael Dreher, Danny D. Jonigk, Maximilian Ackermann

“…The pulmonary vasculature plays a central role in physiological lung function, and vascular remodelling is considered a hallmark of the initiation and progression of pulmonary fibrosis. Different patterns of pulmonary fibrosis commonly exhibit detectable pathological features such as morphomolecular changes, including intussusceptive and sprouting angiogenesis, vascular morphometry, broncho-systemic anastomoses, and aberrant angiogenesis-related gene expression patterns. …”
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