Extracellular vesicle digital scoring assay for assessment of treatment responses in hepatocellular carcinoma patients by Chen Zhao, Yi-Te Lee, Andrew Melehy, Minhyung Kim, Jacqueline Ziqian Yang, Ceng Zhang, Jina Kim, Ryan Y. Zhang, Junseok Lee, Hyoyong Kim, Yong Ju, Yuan-Jen Tsai, Xianghong Jasmine Zhou, Steven-Huy B. Han, Saeed Sadeghi, Richard S. Finn, Sammy Saab, David S. Lu, Jason Chiang, Jae-Ho Park, Todd V. Brennan, Steven A. Wisel, Manaf Alsudaney, Alexander Kuo, Walid S. Ayoub, Hyunseok Kim, Hirsh D. Trivedi, Yun Wang, Aarshi Vipani, Irene K. Kim, Tsuyoshi Todo, Justin A. Steggerda, Georgios Voidonikolas, Kambiz Kosari, Nicholas N. Nissen, Rola Saouaf, Amit G. Singal, Myung Shin Sim, David A. Elashoff, Sungyong You, Vatche G. Agopian, Ju Dong Yang, Hsian-Rong Tseng, Yazhen Zhu

“…At an optimal cutoff of 0.76 identified in the training set, HCC EV TR Score had high accuracy in detecting viable tumors (sensitivity: 76.5%, specificity: 88.2%) and found residual disease not initially observed on MRI in six patients with a median lead time of 63 days. …”
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Cost-effectiveness of an insertable cardiac monitor in a high-risk population in the UK by Mitchell S V Elkind, Claudia I Rinciog, Laura M Sawyer, Alexander Diamantopoulos, Matthew Reynolds, Stylianos I Tsintzos, Paul D Ziegler, Maria E Quiroz, Claudia Wolff, Klaus K Witte

“…Objective To evaluate the cost-effectiveness of insertable cardiac monitors (ICMs) compared with standard of care (SoC) for detecting atrial fibrillation (AF) in patients at high risk of stroke (CHADS2 >2), using a UK National Health Service (NHS) perspective.Methods Using patient characteristics and clinical data from the REVEAL AF trial, a Markov model assessed the cost-effectiveness of detecting AF with an ICM compared with SoC. …”
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Tissue-specific expression and correlation with promoter DNA methylation of the LBP gene in pigs by Yue CAO, Zhong-cheng GAO, Zheng-chang WU, Hai-fei WANG, Wen-bin BAO

“…Lipopolysaccharide binding protein (LBP) is a key factor in the recognition of lipopolysaccharide (LPS) and the initiation of immune response, thus regulating the body's resistance to pathogenic infection. …”
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Seeding Status Monitoring System for Toothed-Disk Cotton Seeders Based on Modular Optoelectronic Sensors by Tao Jiang, Xuejun Zhang, Zenglu Shi, Jingyi Liu, Wei Jin, Jinshan Yan, Duijin Wang, Jian Chen

“…Initially, the monitoring time window is divided using the capacitance sensing signal between two seed drop ports. …”
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Organization of Joint Laboratory Studies during Sanitary and Epidemiological Interventions in the Republic of the Congo by Rospotrebnadzor Specialists by S. A. Portenko, E. V. Naidenova, D. A. Agafonov, D. A. Kuznetsova, A. V. Evteev, A. A. Tushinsky, L. N. Dmitrieva, A. D. Katyshev, V. E. Kuklev, N. Obissa, V. Mabiala, J. Loubano, M. Mpompolo, J.-C. Mobousse Misse, S. A. Shcherbakova, V. V. Kutyrev

“…No DNA/RNA of pathogens has been detected in environmental samples. During culture studies, Salmonella enterica serovar Typhi have been isolated from 8 clinical samples, and their antibiotic sensitivity has been determined. …”
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Cardiac Tamponade Associated with the Presentation of Anaplastic Large Cell Lymphoma in a 2-Year-Old Child by Gema Mira-Perceval Juan, Pedro J. Alcalá Minagorre, Ana M. Huertas Sánchez, Sheila Segura Sánchez, Silvia López Iniesta, Francisco J. De León Marrero, Estela Costa Navarro, María Niveiro de Jaime

“…After a 21-day asymptomatic period, polypnea and tachycardia were detected in a clinical check-up. Chest X-ray revealed a remarkable increase of the cardiothoracic index. …”
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Graves’ disease with hyperfunctioning thyroid nodule harboring thyroid carcinoma. Case report and literature review by A. A. Kuprin, V. Y. Malyuga, I. V. Makedonskaya, A. A. Melnikova

“…According to one of the hypotheses of carcinogenesis, dedifferentiation of thyrocytes occurs initially with the loss of the possibility of the sodium-iodine symporter synthesis, and later of the thyroid-stimulating hormone receptor synthesis by the cell, which reduces the hormone production by tumor cells. …”
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Integrating Artificial Intelligence into Chronic Kidney Disease Care: Enhancing Hemodialysis Scheduling, Comorbidity Management, and Diagnostic Capabilities by Raniah I. Alnaser, Mohammed N. Abed, Fawaz A. Alassaf, Mohammad H. Alsaaty

“…AI is used in kidney disease to predict CKD progression, evaluate drug prescriptions, detect medical errors, adjust dialysis schedules, and identify unknown comorbidities and phenotypes. …”
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Artificial intelligence in oncologic imaging: enhancing diagnostic precision towards facilitating clinical decision-making by Mariusz J. Kujawa, Leonor Cerda-Alberich, Luis Marti-Bonmati

“…AI-based tools have shown high accuracy in analyzing images to detect and classify tumors and assess treatment response. …”
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Levodopa induces thyroid function regulation in a patient with thyroid hormone resistance and Parkinson’s disease: a case report by Gabriela Rozo-Paz, Clara Maria Ruiz-Forero, José David Suárez-Mera, Guillermo Monsalve Duarte, William Kattah Calderón

“…During the endocrinology consults, elevated thyroid hormone levels were detected without an adequate TSH response, and THR was suspected. …”
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A comparative proteomic-based study identifies essential factors involved in hair follicle growth in inner Mongolia cashmere goats by Rile Nai, Chongyan Zhang, Yuchun Xie, Duhu Man, Haijun Li, Lina Ma, Lu Mi, Meng Zhao, Qier Mu, Lixia Gao, Zhihong Liu, Jinquan Li

“…The growth of cashmere fibre initiates when the relatively inactive telogen stage transitions to the anagen stage, which involves active proliferation. …”
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Management of drug-induced liver injury associated with anti-cancer therapy by Bruno Vincenzi, Mao Yimin, Raúl J. Andrade, Raúl J. Andrade, Mauricio Morales Castillo, Gamar Akhundova-Unadkat, José M. Mato

“…Treatment with hepatoprotective agents which is usually initiated after DILI has been detected and involves cessation of causative anti-cancer therapy, has demonstrated improvements in liver enzyme elevation. …”
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Iterative refinement and goal articulation to optimize large language models for clinical information extraction by David Hein, Alana Christie, Michael Holcomb, Bingqing Xie, AJ Jain, Joseph Vento, Neil Rakheja, Ameer Hamza Shakur, Scott Christley, Lindsay G. Cowell, James Brugarolas, Andrew R. Jamieson, Payal Kapur

“…We present a novel, end-to-end pipeline leveraging large language models (LLMs) for highly accurate information extraction and normalization from unstructured pathology reports, focusing initially on kidney tumors. Our innovation combines flexible prompt templates, the direct production of analysis-ready tabular data, and a rigorous, human-in-the-loop iterative refinement process guided by a comprehensive error ontology. …”
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Systemic Mastocytosis: A Rare Case of Increased Liver Stiffness by Stefanie Adolf, Gunda Millonig, Helmut Karl Seitz, Andreas Reiter, Peter Schirmacher, Thomas Longerich, Sebastian Mueller

“…An additional CT scan detected disseminated bone lesions. After three months of treatment with Midostaurin, LS slightly decreased down to 31.9 kPa (IQR 8.3 kPa). …”
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FT-IR Characterization of Pollen Biochemistry, Viability, and Germination Capacity in Saintpaulia H. Wendl. Genotypes by Erzsebet Buta, Maria Cantor, Răzvan Ștefan, Rodica Pop, Ioana Mitre, Mihai Buta, Radu E. Sestraș

“…FT-IR characterization of pollen biochemistry was analyzed to detect possible connection with the viability (by staining with potassium iodide, 25%) and the germination capacity (on solid nutrient medium), in 15 Saintpaulia genotypes. …”
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Effect of genetic transformation via Agrobacterium rhizogenes on the anatomical characteristics of Eruca Sativa Mill. plants by Raghad Abdullah, Rasha Al-Jirjees, Shifa Salih

“…Callus was successfully initiated from hairy roots on both Murashige-Skoog (MS) and Woody plants (WP) media containing (0.4 and 0.5 mg. …”
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Research Progress of Grating-Based X-Ray Phase-Contrast Imaging and Key Devices by Fangke Zong, Jun Yang, Jinchuan Guo, Jingjin Zhang, Yang Du, Chenggong Zhang

“…This article initially explores the fundamental principles of X-ray phase-contrast imaging and several prevalent imaging techniques. …”
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Molten Pool Image Segmentation Based on Adaptive Multi-Scale Attention Mechanism by Yuefeng Chen, Weihua Liu, Qing Yang, Huabin Chen, Qi Jiang

“…Subsequently, a tailored Lossab loss function is devised to boost the network’s precision in detecting the edges of the molten pool. Experimental outcomes reveal that the proposed method attains a remarkable segmentation accuracy of 96.77% within the molten pool region on the TIG molten pool image dataset. …”
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Bath: a Bayesian approach to analyze epigenetic transitions reveals a dual role of H3K27me3 in chondrogenesis by Christoph Neu, Manuela Wuelling, Christoph Waterkamp, Daniel Hoffmann, Andrea Vortkamp

“…Interestingly, we also detected a complex extension of the classical bivalent state (H3K4me3/H3K27me3) consisting of several activating promoter marks besides the repressive mark H3K27me3. …”
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Smoking and asthma mediate the protective effect of educational attainment on chronic obstructive pulmonary disease risk: a mediation Mendelian randomization analysis by Xue Bai, Lantao Chen, Fenghai Ren, Ying Zhao, Yue Zheng, Yanbo Wang, Sainan Pang, Jian Zhang, Erliang Guo, Huiyan Li

“…In the reduction of the COPD risk by years of schooling, the mediating effects of smoking initiation and asthma accounted for 32.8% and 6.9% respectively. …”
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