Autoimmune Hepatitis Triggered by Anti-TNF- Therapy by Satoshi Nakayama

“…A 52-year-old Japanese woman with psoriasis developed liver damage two months after initiation of anti-TNF-α therapy with adalimumab. Liver histological findings were compatible with AIH, and positive conversions of ANAs were detected. …”
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Injury-Driven Structural and Molecular Modifications in Nociceptors by Mario García-Domínguez

“…Peripheral tissue injury initiates a multifaceted cascade of structural and molecular modifications within nociceptors, the primary sensory neurons tasked with detecting noxious stimuli. …”
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Novel insecticide resistance mutations associated with variable PBO synergy in Anopheles gambiae s.l. from the Democratic Republic of Congo by Bethanie Pelloquin, Fiacre Agossa, Holly Acford-Palmer, Tiffany Clark, Sheila B. Ogoma, Miriam Williams, Narcisse Basosila, Francis Watsenga, Emery Metelo, Richard M. Oxborough, Yibayiri Osee Sanogo, Ferdinand Ntoya, Emma Collins, Sophie Moss, Charles McLoughlin, Monica Campos, Jody Phelan, Mark Rowland, Thomas Walker, Noboru Minakawa, Emile Zola Manzambi, Eric Mukomena, Susana Campino, Louisa A. Messenger

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Tularemia in Bulgaria 2003-2004 by Radka Komitova, Rumiana Nenova, Plamen Padeshki, Ivan Ivanov, Vassil Popov, Petar Petrov

“…Francisella tularensis (F. tularensis) was detected by PCR, providing a definitive diagnosis in 82.3% of the cases. …”
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Brain Infarction in Botulism (Clinical Case) by R. E. Kalinin, E. Kh. Barinov, D. V. Sundukov

“…In 6 out of 89 criminal «iatrogenic» cases initiated by investigative authorities in the Moscow region in 2016–2018 anesthesiological or intensive care in the ICU was the subject of investigation. …”
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Discovering and modeling hidden periodicities in science data by Antonio Napolitano, William A. Gardner

“…The popularity stems from the fact that detecting and characterizing periodicities can provide a means for extracting information from science data—information that might not otherwise be accessible. …”
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An ACTH-Producing Neuroendocrine Tumor: Clinical Course of Multidisciplinary Therapy Including Peptide Receptor Radionuclide Therapy – A Case Report by Tomonobu Koizumi, Ai Sato, Kohei Kitajima, Masanori Yamazaki, Sana Kanazawa, Tsuyoshi Notake, Yoshinori Sato, Shota Kobayashi, Mai Iwaya, Takako Umeda, Mitsuhisa Komatsu

“…ACTH levels increased after initiation of PRRT, and clinical manifestations, such as pigmentation, hypertension, and hyperglycemia, were remarkable. …”
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Spontaneous Dramatic Regression of Clear Cell Renal Cell Carcinoma After Pazopanib-Induced Severe Systemic Inflammatory Syndrome: A Case Report and Literature Review by Chi Hyuk Oh, Hong Jun Kim

“…This case report presents a unique instance of spontaneous dramatic tumor regression in a 42-year-old Korean male diagnosed with clear cell RCC. The patient initially presented with right lower back pain, weight loss, and a loss of appetite. …”
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Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse. by Federica Federici, Aristea Magaraki, Evelyne Wassenaar, Catherina J H van Veen-Buurman, Christine van de Werken, Esther B Baart, Joop S E Laven, J Anton Grootegoed, Joost Gribnau, Willy M Baarends

“…In addition, no Xist expression was detected in male and female morulas that developed from oocytes fertilized with mature ΔXist sperm. …”
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The N-formyl peptide receptors: much more than chemoattractant receptors. Relevance in health and disease by Filomena Napolitano, Nunzia Montuori, Nunzia Montuori

“…Pattern Recognition Receptors (PRRs) are a superfamily of receptors that detect molecular structures typical for pathogens and damaged cells and play a crucial role in the proper function of the innate immune system. …”
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Study of some virulence genes from uropathogenic Klebsiella pneumoniae and Pseudomonas aeruginosa isolated in Wasit Province, Iraq by Rana H. Raheema, Sabaa Hilal Hadi, Zainab Adil Ghani Chabuck

“…Materials and Methods: Initially, 100 clinical urine samples were taken for this investigation from (October 1 to December 1, 2022), and the isolates were initially identified using culture, microscopic analysis, and biochemical assays. …”
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Deciphering the pseudouridine nucleobase modification in human diseases: From molecular mechanisms to clinical perspectives by Shiheng Jia, Xue Yu, Na Deng, Chen Zheng, Mingguang Ju, Fanglin Wang, Yixiao Zhang, Ziming Gao, Yanshu Li, Heng Zhou, Kai Li

“…Increased pseudouridylation is frequently associated with tumour initiation, progression, and poor prognosis, whereas its reduction is predominantly implicated in non‐tumour diseases. …”
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Screening a nation for hepatitis C virus elimination: a cross-sectional study on prevalence of hepatitis C and associated risk factors in the Rwandan general population by Neil Gupta, Justine Umutesi, Carol Yingkai Liu, Michael J Penkunas, Jean Damascene Makuza, Corneille K Ntihabose, Sabine Umuraza, Julienne Niyikora, Janvier Serumondo, Sabin Nsanzimana

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Cutibacterium Acnes induces Alzheimer’s disease-like pathology in brains of wistar rats through structural changes associated with microtubules by Morteza Aliashrafi, Mohammad Nasehi, Seyed Davar Siadat, Mohammad-Hossein Mohammadi-Mahdiabadi-Hasani, Hakimeh Zali, Zahra Niknam

“…Abstract Background Cutibacterium acnes ( C. acnes), a Gram-positive anaerobe and a dominant bacterium species in the sebaceous follicles of the face was detected in the brain of Alzheimer’s disease (AD) patients. …”
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Abdominal B-Cell Lymphoma Mimicking Ovarian Cancer by Dennis Jung, Lina Judit Schiestl, Simin Schadmand-Fischer, Arno Schad, Annette Hasenburg, Roxana Schwab

“…In gynecological sonography ascites, an ovarian cyst and peritoneal carcinosis in the pouch of Douglas were detected, which were potentially indicative of ovarian cancer. …”
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Long-term follow-up of combination therapy with pembrolizumab and anlotinib in thoracic SMARCA4-deficient undifferentiated tumor: a case report and molecular features by Ting Duan, Mingxin Xu, Haibo Zhang, Shengchang Wu, Haochu Wang, Zhenying Guo

“…After 46 cycles, the patient demonstrated no disease progression with a PR lasting 31 months and long progression-free survival(PFS) of 43 months. The lung tumor was initially detected in September 2020, and the patient remained alive at the latest follow-up in November 2024. …”
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Case Report: Dramatic response to entritinib in a patient with gastrointestinal stromal tumor positive for NTRK3 fusion by Guomin Dong, Pengyu Han, Zhiyun Zhang, Qian Ge, Jian Jiang, Suoni Li, Jiequn Ma, Jie Bai, Hui Wei, Zheng Zhao

“…Continued oral imatinib adjuvant therapy was initiated. In 2024, disease progression was observed with residual KIT mutation (VAF 1.10%) and new-onset ETV6:NTRK3 fusion (VAF 35.29%) detected by circulating tumor DNA (ctDNA) analysis. …”
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No Evidence of XMRV or MuLV Sequences in Prostate Cancer, Diffuse Large B-Cell Lymphoma, or the UK Blood Donor Population by Mark James Robinson, Philip William Tuke, Otto Erlwein, Kate I. Tettmar, Steve Kaye, Kikkeri N. Naresh, Anup Patel, Marjorie M. Walker, Takahiro Kimura, Ganesh Gopalakrishnan, Richard S. Tedder, Myra O. McClure

“…To control for mouse DNA contamination, a PCR that detected intracisternal A-type particle (IAP) sequences was included. …”
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Identification of diagnostic and prognostic genetic alterations in uveal melanoma using RNA sequencing by Rogier J. Nell, Mieke Versluis, Davy Cats, Hailiang Mei, Robert M. Verdijk, Wilma G. M. Kroes, Gregorius P. M. Luyten, Martine J. Jager, Pieter A. van der Velden

“…Here, we tested the detectability of all key mutations and chromosomal changes from RNA sequencing data in 80 primary uveal melanomas studied by The Cancer Genome Atlas (TCGA) initiative, and in five prospective cases. …”
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Ponatinib as a Valid Alternative Strategy in Patients with Blast Crisis-Chronic Myeloid Leukemia Not Eligible for Allogeneic Stem Cells Transplantation and/or Conventional Chemothe... by Cristina Bucelli, Daniele Cattaneo, Valeria Ferla, Manuela Zappa, Caterina de Benedittis, Simona Soverini, Alessandra Iurlo

“…Here we report the case of a 61-year-old man diagnosed with B-cell lymphoid BC-CML, initially treated with imatinib 800 mg day and then with dasatinib 140 mg day because of intolerance. …”
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