An expedited cardiology investigation service helps to bridge the gap between emergency and outpatient care by Jun Yu Chen, Hibba Saeed, Jemimah Joseph, Mostafa Sallam, Joe Bradley, Vinay Reddy-Kolanu

“…It promotes safe discharge while facilitating early detection of pertinent cardiac pathology and prompt initiation of treatment. …”
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Delayed culture conversion predicts poor outcomes for isoniazid mono-resistant TB in Uganda: a retrospective cross-sectional study from 2017– 2022 by Joel Kabugo, Obondo James Sande, Jupiter Marina Kabahita, Joanita Namutebi, Dennis Mujuni, Hellen Rosette Oundo, Daniel Kisakye, Dorothy Nassozi Batte, Moses Joloba, Gerald Mboowa

“…This emphasizes the need for prompt detection using routine point-of-care testing molecular diagnostic platforms to test for Isoniazid and Rifampicin resistance to improve TB treatment outcomes and reduce failures. …”
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Prevalence of low-level viremia in people living with HIV/AIDS and its impact on virological failure in Guizhou Province, China by Yan Zheng, Xinling Zha, Hai Long, Wenji Zeng, Junhua Wang, Yongming Yao, Lu Huang, Xiaotian Song, Maosi Wang, Yang Chen, Yang Chen

“…LLV occurrence frequency was divided into two groups: intermittent LLV (iLLV) was defined as one independent LLV with both the previous and the subsequent viral load below the lower limit of detection. Persistent LLV (pLLV) was defined as at least two consecutive episodes of LLV. …”
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Active management of suspected fetal macrosomia: the right approach? by Inmaculada Mejía, Patricia Barbero Casado, Claudia Sánchez-Arevalo, Christian Garrido Lopez, Laura Escudero Villegas, Antonio García Burguillo, Alberto Galindo, Cecilia Villalaín

“…Among non-diabetic patients 125/125 (100%) had their follow-up scan of which 45/125 (36%) fetuses had an EFW ≥4000 g and 32/45 (71.1%) patients opted for an elective labor induction due to suspected fetal macrosomia (the rest did not meet induction criteria or initiated spontaneous onset of labor). The average neonatal weight in this group was 3975 ± 285 g. …”
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Colonization of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci and its associated factors in cancer patients at the University of Gondar Comprehen... by Eden Getaneh Mekonnen, Abebe Birhanu, Mulugeta Yimer, Segenet Bizuneh, Mucheye Gizachew, Baye Gelaw

“…The Pearson Chi-Square test was initially used to evaluate the association between factors and outcomes as the preliminary analysis, with a significance threshold of p <  0.05. …”
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The State of Artificial Intelligence and its Prospects in Pakistan's Medical Sector by Rohail Akhtar Habib, Yumna Sattar Khan

“…One possible result of AI integration is the early detection of diseases, especially in rural locations where access to expert medical care is limited. …”
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GenomicGapID: leveraging spatial distribution of conserved genomic sites for broad-spectrum microbial identification by Vishwaratn Asthana, Pallavi Bugga, Clara Elaine Smith, Catherine Wellman, Zachary Dwight, Piyush Ranjan, Erika Martínez Nieves, Robert P. Dickson, J. Scott VanEpps

“…ABSTRACT Bacterial detection and identification methods can be broadly classified as either untargeted with expansive taxonomic coverage or targeted with narrow taxonomic focus. …”
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Prevalence and associated factors of HIV among female sex workers in Eastern and Southern Africa: Systematic review and meta-analysis. by Tigabu Kidie Tesfie, Getaneh Awoke Yismaw, Bantie Getnet Yirsaw, Habtamu Wagnew Abuhay, Meron Asmamaw Alemayehu, Nebiyu Mekonnen Derseh, Gebrie Getu Alemu, Muluken Chanie Agimas

“…Clinicians could facilitate early detection and treatment of STIs, and Hepatitis B virus infection.…”
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Rural-urban disparities in breast cancer survival in the context of the national breast cancer screening program for rural women in China by Xing Xing, Qing Wang, Xiaoyun Liu, Fuzhong Xue, Qingyue Meng, He Zhu

“…Background: Breast cancer is the most diagnosed cancer and is the second leading cause of cancer death among women in China. To improve early detection and treatment intake, China initiated a national breast and cervical cancer screening program targeting rural women aged 35 to 64 years, with an investment exceeding $220 million by 2018. …”
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Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study. by Charlotte Schutz, David Barr, Bruno B Andrade, Muki Shey, Amy Ward, Saskia Janssen, Rosie Burton, Katalin A Wilkinson, Bianca Sossen, Kiyoshi F Fukutani, Mark Nicol, Gary Maartens, Robert J Wilkinson, Graeme Meintjes

“…Antituberculosis therapy was initiated in 566/576 (98.3%) and 487/576 (84.5%) started therapy within 48 hours of enrolment. …”
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The cutting type of vegetables influences the spontaneous fermentation rate by Valence, Florence, Junker, Romane, Baty, Céline, Rué, Olivier, Mariadassou, Mahendra, Madec, Marie Noëlle, Maillard, Marie-Bernadette, Bage, Anne-Sophie, Chuat, Victoria, Marché, Laurent, Thierry, Anne

“…Leuconostoc was only detected with gyrB and vice-versa for Clostridium. …”
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Quantitative trait locus mapping for salt and drought tolerance traits in wheat (Triticum aestivum L.) by Xiaotong Liu, Tao Sun, Zihan Zhou, Yahui Tong, Zixin Zhou, Haotian Cao, Jiale Qu, Ze Li, Qiwei Yang, Mingyang Xu, Bin Zhang, Ningze Wang, Yongzhen Wu, Han Sun, Chunhua Zhao, Ran Qin, Fa Cui

“…The germination stage is the initial growth stage of wheat growth, when wheat is particularly sensitive to salt and drought stress. …”
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TREATMENT OF BLAST PHASE MYELOPROLIFERATIVE NEOPLASM WITH THE COMBINATION OF AZACITIDINE, VENETOCLAX AND RUXOLITINIB by Fidan Khalilova, Azer Kerimov, Gulnar Kerimova

“…., born in 1955, was registered at the NCHBT in June 2019 with a diagnosis of PMF. At the time of initial admission, the patient complained of abdominal distension and severe weight loss over the past 6-months. …”
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The Evaluation of Tectonic Activity in Eshtehard Plain Basin with Interferometry by Farrin Nayebzadeh, Aghil Madadi, Ghasem Azizi

“…Then, in a field visit of the area, the landforms drawn on the map, were matched within the landforms on the earth and the items that were hard to detect on the map, were recognized. Finally, the supplementary map was detected. …”
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Hybrid epithelial-mesenchymal status of lung cancer dictates metastatic success through differential interaction with NK cells by Ugo Pastorino, Massimo Milione, Paola Orecchia, Massimo Moro, Gabriella Sozzi, Monica Parodi, Giovanni Centonze, Fabio Murianni, Francesca Andriani, Ilaria Roato, Cecilia Gardelli, Melissa Balsamo, Giulia Taiè, Andrea Petretto, Chiara Lavarello ‎, Luca Roz, Massimo Vitale, Giulia Bertolini

“…Here we characterize the pro-metastatic mechanics of non-small cell lung cancer (NSCLC) H-cells and their subset of cancer-initiating cells (CICs), dissecting crucial interactions with NK cells.Methods Human lung cancer cell lines and sublines representative of E, M, or H states, assessed by proteomics, were analyzed in vivo for their tumor-forming and disseminating capabilities. …”
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Optimisation of the cultured ELISpot/Fluorospot technique for the selective investigation of SARS-CoV-2 reactive central memory T cells by Jack R. Jerome, Jack R. Jerome, Kirsty L. Wilson, Kirsty L. Wilson, Joshuah Fialho, Joshuah Fialho, Georgia Goodchild, Georgia Goodchild, Monica D. Prakash, Monica D. Prakash, Charlie McLeod, Charlie McLeod, Charlie McLeod, Charlie McLeod, Peter C. Richmond, Peter C. Richmond, Peter C. Richmond, Peter C. Richmond, Vasso Apostolopoulos, Katie L. Flanagan, Katie L. Flanagan, Katie L. Flanagan, Magdalena Plebanski, Magdalena Plebanski

“…IntroductionThis study presents an optimised cultured ELISpot protocol for detecting central memory T-cell interferon gamma (IFNγ) responses against SARS-CoV-2 peptides following an initial priming with either peptides, or whole spike protein.MethodsKey variations optimised include the culture length, timing of exogenous survival signals (IL-2), and endpoint analysis modality and cell density to enhance assay sensitivity without compromising specificity for central memory T-cell IFNγ recall responses to cognate antigen.ResultsWe noted a culture duration of 10 days, combined with a delayed IL-2 administration on day 5 to enhance assay sensitivity while maintaining response specificity towards cognate antigen when compared with shorter culture periods or earlier exogenous survival signal provision. …”
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Optimization of the treatment of patients with severe chronic urticaria by Ye.M. Dytiatkovska, N.O. Nedohybchenko

“…Indicators of urticaria activity (UAS7) and quality of life (SKINDEX-29) in patients were determined before the start of treatment and at each of the visits (on the 10th, 31st and 52nd days of therapy when treated with omalizumab and five and nine weeks after initiation of desloratadine therapy), and UAS7 was assessed six months after the end of treatment. …”
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High-Throughput Indirect Monitoring of TORC1 Activation Using the pTOMAN-G Plasmid in Yeast by Melissa Gómez, Guilherme Rocha, Diego Ruiz, Claudio Martínez, Francisco Salinas, Eduardo Kessi-Pérez

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Seropositive juvenile rheumatoid arthritis: analysis of the spectrum of clinical manifestations and therapy according to a retrospective study by М. I. Kaleda, I. P. Nikishina, E. S. Fedorov, S. V. Arsenyeva, A. N. Shapovalenko

“…When choosing a BA, preference was given to tocilizumab or rituximab (RTM) in patients with seropositive JRA in the presence of systemic manifestations, and high clinical and laboratory activities and to RTM or ABC in those with detected Sjögren's syndrome.Conclusion. Seropositive JRA is a rare subtype of JIA that has an initially unfavorable course. …”
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Development and validation of a carotid plaque risk prediction model for coal miners by Yi-Chun Li, Yi-Chun Li, Yi-Chun Li, Tie-Ru Zhang, Tie-Ru Zhang, Tie-Ru Zhang, Fan Zhang, Fan Zhang, Fan Zhang, Chao-Qun Cui, Chao-Qun Cui, Chao-Qun Cui, Yu-Tong Yang, Yu-Tong Yang, Yu-Tong Yang, Jian-Guang Hao, Jian-Ru Wang, Jiao Wu, Hai-Wang Gao, Ying-Bo Liu, Ming-Zhong Luo, Li-Jian Lei, Li-Jian Lei, Li-Jian Lei

“…The features were initially screened using extreme gradient boosting (XGBoost), random forest, and LASSO regression, and the model was subsequently constructed using logistic regression. …”
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