Dynamic changes and prognostic value of glutathione S-transferase alpha in mild cognitive impairment and Alzheimer’s disease by Yangyang Tang, Ni Li, Linyan Dai, Xingsheng Wang, Xia Lai

“…This suggests that GSTα protein could potentially act as a biomarker for both MCI and AD, offering fresh insights for early detection and intervention strategies.…”
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Electrocardiogram screening for school children: a cross-sectional, population-based study by Ali A. Alakhfash, Abdulrahman Al Mesned, Waleed Al-Manea, Abdulla Al Qwaee, Zuhair Nasser Al-Hassnan

“…BACKGROUND: Identification of life-threatening arrhythmogenic disorders, which may present during infancy, childhood, or later stages, enables the early initiation of effective preventive therapies. Electrocardiogram (ECG) screening may detect conditions that elevate risk of sudden cardiac death (SCD) at an early stage. …”
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Compositional transformations can reasonably introduce phenotype-associated values into sparse features by George I. Austin, Tal Korem

“…While we do not intend to address other concerns regarding tumor microbiome analyses, validate Poore et al.’s results, or evaluate batch-correction pipelines, we conclude that because phenotype-associated features that were initially sparse can be created by a sample-wise transformation that cannot artifactually inflate machine learning performance, their detection is not independently sufficient to demonstrate information leakage in machine learning pipelines. …”
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Dyslipidemia and its associated factors in Ethiopia: a systematic review and meta-analysis by Addisu Getie, Temesgen Ayenew, Mihretie Gedfew, Baye Tsegaye Amlak

“…Health professionals should also prioritize early detection and management in high-risk groups to reduce long-term cardiovascular risks.…”
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Brain tau PET-based identification and characterization of subpopulations in patients with Alzheimer’s disease using deep learning-derived saliency maps by Yanxiao Li, Xiuying Wang, Qi Ge, Manuel B Graeber, Shaozhen Yan, Jian Li, Shuyu Li, Wenjian Gu, Shuo Hu, Tammie L. S. Benzinger, Jie Lu, Yun Zhou

“…We included 615 cognitively normal and 159 AD brain 18F-flortaucipr PET scans, along with T1-weighted MRI from the Alzheimer Disease Neuroimaging Initiative database. A three dimensional-convolutional neural network model was employed for AD detection using standardized uptake value ratio (SUVR) images. …”
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Scheie Syndrome Diagnosis in Early Childhood: Case Study by Nataliya V. Buchinskaya, Anastasia O. Vechkasova, Ekaterina D. Ganina, Ekaterina Е. Shipovskova, Victoriya A. Lapina, Yana A. Ananyeva, Nataliya V. Zhurkova, Nato D. Vashakmadze, Vladimir M. Kenis, Mikhail M. Kostik

“…Diagnosis of the mild form of mucopolysaccharidosis type I (MPS I) — Scheie syndrome — can be problematic due to its non-specific manifestations. However, its early detection is crucial for the timely therapy initiation and for improving patients’ quality of life. …”
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ADeepWeeD: An adaptive deep learning framework for weed species classification by Md Geaur Rahman, Md Anisur Rahman, Mohammad Zavid Parvez, Md Anwarul Kaium Patwary, Tofael Ahamed, David A. Fleming-Muñoz, Saad Aloteibi, Mohammad Ali Moni, PhD

“…Deep Learning (DL) methodologies have been recently implemented to revolutionise agricultural practices, particularly in weed detection and classification. Existing DL-based weed classification techniques, including VGG16 and ResNet50, initially construct a model by implementing the algorithm on a training dataset comprising weed species, subsequently employing the model to identify weed species acquired during training. …”
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Recurrence of cervical precancer after excisional treatment: risks and prevention by T. V. Klinyshkova, M. S. Buyan

“…Genital papillomavirus infection is widespread in the population, initiating the development of precancer and genital cancer. …”
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Systematic Review of Screening and Surveillance Programs to Protect Workers from Nanomaterials. by Mary Gulumian, Jos Verbeek, Charlene Andraos, Natasha Sanabria, Pieter de Jager

“…<h4>Background</h4>Screening and surveillance approaches for workers exposed to nanomaterials could aid in early detection of health effects, provide data for epidemiological studies and inform action to decrease exposure. …”
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Clinical application of exempting anti-D monitoring in pregnant women with Asian-type DEL by YI Pin, OU Ziyu, SUN Xiaoxiao, WANG Mingming, WU Changlin, SHAO Chaopeng

“…In the true negative group, anti-D antibodies were detected in 20 cases, of which 6 cases tested positive for HDFN. …”
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Fibrolamellar hepatocellular carcinoma: a case report and gene analysis by Akira Watanabe, Norifumi Harimoto, Hideyuki Saito, Reika Kawabata-Iwakawa, Takaomi Seki, Ryo Muranushi, Kouki Hoshino, Kei Hagiwara, Norihiro Ishii, Mariko Tsukagoshi, Takamichi Igarashi, Kenichiro Araki, Hayato Ikota, Takashi Ishige, Koshi Mimori, Ken Shirabe

“…The patient experienced a single lymphatic recurrence on the hepatoduodenal ligament 12 months after the initial surgery. We performed lymphadenectomy for the recurrent tumor. …”
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Prospects of artificial intelligence for the sustainability of sugarcane production in the modern era of climate change: An overview of related global findings by Rajan Bhatt, Akbar Hossain, Debjyoti Majumder, Mandapelli Sharath Chandra, Rajiv Ghimire, Muhammad Faisal Shahzad, Krishan K. Verma, Amarinder Singh Riar, Vishnu D. Rajput, Mauro Wagner Oliveira, Adel Nisi, Riyadh S. Almalki, Viliam Bárek, Marian Brestic, Sagar Maitra

“…This study discusses the latest research on artificial intelligence (AI) in sugarcane farming, with particular attention given to soil biochemistry, disease detection, climate-smart technology for greenhouse gas emissions, yield and water productivity prediction, and cane juice biochemistry. …”
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Acute toxicity of atrazine degradation solutions via advanced oxidation processes: An experimental and in-silico approach based on mass spectrometry data. by Junting Hong, Messika Revel, Nadia Boussetta, Gérald Enderlin, Frederic Nadaud, Clarisse Roig, Lauresse Nguimapi Tsague, Stéphane Firmin, Nabil Grimi, Franck Merlier

“…Although atrazine has been banned, residues of the compound and its metabolites are still detected in certain areas of French groundwater. In response to the European Green Deal, this study focuses on the degradation of atrazine in tap water and the toxicological evolution of different treatments. …”
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Analysis of RBP expression and binding sites identifies PTBP1 as a regulator of CD19 expression in B-ALL by Nicole Ziegler, Mariela Cortés-López, Francesca Alt, Maximilian Sprang, Arsenij Ustjanzew, Nadine Lehmann, Khalifa El Malki, Arthur Wingerter, Alexandra Russo, Olaf Beck, Sebastian Attig, Lea Roth, Julian König, Claudia Paret, Jörg Faber

“…However, early molecular determinants suggesting therapy resistance as well as the time point when first signs of epitope loss appear to be detectable are not enlightened so far. By deep sequencing of the CD19 locus, we identified a blast-specific 2-nucleotide deletion in intron 2 that exists in 35% of B-ALL samples at initial diagnosis. …”
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An Affordable AI-Driven and 3D-Printed Personalized Myoelectric Prosthesis: Design, Development, and Assessment by Enzo Romero, Jose G. Garcia, Magno Parra, Sebastian Caballa, Alejandro M. Saldarriaga, Edson F. Luque, Dante J. Rodriguez, Victoria E. Abarca, Dante A. Elias

“…This demonstrated robust functional performance, comparable to high-end commercial devices in initial tests. Gross motor tasks saw 100% success rates; fine motor tasks, 22.2%. …”
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Differentiation grade as a risk factor for lymph node metastasis in T1 colorectal cancer by Osamu Shiina, Shin‐ei Kudo, Katsuro Ichimasa, Yuki Takashina, Yuta Kouyama, Kenichi Mochizuki, Yuriko Morita, Takanori Kuroki, Shun Kato, Hiroki Nakamura, Shingo Matsudaira, Masashi Misawa, Noriyuki Ogata, Takemasa Hayashi, Kunihiko Wakamura, Naruhiko Sawada, Toshiyuki Baba, Tetsuo Nemoto, Fumio Ishida, Hideyuki Miyachi

“…Methods We retrospectively evaluated 971 consecutive patients with T1 CRC who underwent initial or additional surgical resection from 2001 to 2021 at our institution. …”
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Persistence of SARS-CoV-2 in COVID-19 patients during the second wave of the pandemic in India by Arghya Das, Ashima Jain Vidyarthi, Salman Khan, Sheetal Singh, Kiran Bala, LaxmiTej Wundavalli, Manali Agarwal, Jaweed Ahmed, Amit Sehgal, Pragati Grover, Parwez, Maitrayee Narayan, Bharat Chandra Das, Amit Chauhan, Sushma Bhatnagar, Anant Mohan, Urvashi B. Singh, Rama Chaudhry

“…Results: All 51 patients tested positive for SARS-CoV-2 RNA at the 5th week of initial laboratory confirmation of COVID-19. The majority of the patients (38; 74.5%) remained positive for viral RNA till the 6th week and the median duration of viral positivity was 45 days. …”
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From Repetitive Head Trauma to Neurodegeneration: A Comprehensive Review of CTE by Marta Piotraszewska, Magda Skudzińska, Magdalena Bartold, Maria Irena Grys, Filip Kochański, Janina Pohrybieniuк, Karolina Wołk, Aleksandra Jaskulska, Jan Pietrzak, Dominika Błonka

“…Extensive research is underway to identify fluid biomarkers (e.g., NfL, p-tau, GFAP, UCH-L1, S100B) and neuroimaging modalities (e.g., PET, MRI, DTI) that may enable in vivo detection of CTE and differential diagnosis from other tauopathies. …”
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Predicting pathogen evolution and immune evasion in the age of artificial intelligence by D.J. Hamelin, M. Scicluna, I. Saadie, F. Mostefai, J.C. Grenier, C. Baron, E. Caron, J.G. Hussin

“…The genomic diversification of viral pathogens during viral epidemics and pandemics represents a major adaptive route for infectious agents to circumvent therapeutic and public health initiatives. Historically, strategies to address viral evolution have relied on responding to emerging variants after their detection, leading to delays in effective public health responses. …”
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Cytomegalovirus-induced oncomodulation drives immune escape in glioblastoma by Harald Krenzlin, Felix Corr, Deepak Ailani, Philipp Einheuser, Thomas Bukur, Thomas Rößler, Alina Henrich, Raja Hollnagel, Alice Dauth, Libo Hu, Leon Schmidt, Marion Griessl, Michael Gutknecht, Noe Mercado, Beat Alessandri, Charles H. Cook, Florian Ringel, Sean E. Lawler, Niels A. Lemmermann, Naureen Keric

“…In vivo, the mCMV immediate early gene (IE1) was detected in brains of mCMV + animals after tumor implantation and increased during tumor growth. mCMV + mice had significantly shorter survival than controls, depending on initial tumor size (P < 0.001). …”
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