MiR-455-5p Mitigates Interleukin-1 β-induced Chondrocyte Damage Linked to Osteoarthritis by Targeting TNFAIP8 by Tao Zhang, Wei Wang, Jinlei Sun, Long Luo, Yuan Li, Zhixiong Xu, Wensheng Xu

“…An enzyme-linked immunosorbent assay was performed to measure the concentrations of inflammation factors, and oxidative stress was evaluated by detecting superoxide dismutase activity and malondialdehyde levels. …”
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Clinical case and features of progression of dermatomyositis with anti-Mi2 antibodies by I. V. Devald, E. A. Khodus, M. S. Belsner, O. L. Minakina, D. S. Stashkevich

“…Laboratory examination showed increased erythrocyte sedimentation rate of 40 mm/h and lactate dehydrogenase level of 672 U/L, antinuclear factor was measured at 1:320, and anti-Mi2 antibodies were detected by MSAs panel. Combination immunosuppressive therapy with methylprednisolone at an initial dose of 1 mg/kg/day and subcutaneous methotrexate at a dose of 15 mg/week was initiated, followed by correction depending on the clinical and laboratory dynamics. …”
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Solar background radiation temperature calibration of a pure rotational Raman lidar by V. Jayaweera, R. J. Sica, G. Martucci, A. Haefele, A. Haefele

“…These measurements enable climatology studies and trend analyses to be performed. To detect long-term trends it is critical that the calibration of the system and the monitoring of its associated uncertainties are as reliable and continuous as possible. …”
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Comparative Investigation of Untargeted and Targeted Metabolomics in Turmeric Dietary Supplements and Rhizomes by Jashbir Singh, Fakir Shahidullah Tareq, Devanand L. Luthria

“…In the present study, we analyzed the bioactive curcuminoids content in eight capsules (DS-1-DS-7 and DS-9), one tablet (DS-8), three ground turmeric samples (DS-10-DS-12), and three ground turmeric rhizomes (TR-1, TR-2, and TR-3). Initial screening with infrared and ultraviolet–visible spectroscopy coupled with a principal component analysis (PCA) revealed distinct differences between the samples analyzed. …”
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HD-OCT Angiography and SD-OCT in Patients with Mild or No Clinically Apparent Diabetic Retinopathy by Maja Vinković, Andrijana Kopić, Tvrtka Benašić, Dubravka Biuk, Ivanka Maduna, Stela Vujosevic

“…They also present retinal changes at the GCC that are correlated with initial neurodegeneration. HD-OCTA and SD-OCT can detect vascular changes and structural signs of retinal neurodegeneration before clinically apparent diabetic retinopathy. …”
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A Tale of Two Conditions: Pediatric Brugada Syndrome Unveiled—Navigating the Challenges of Coexisting Arrhythmia and Fever‐Induced ECG Pattern by Hei‐To Leung, Sit‐Yee Kwok, Fong‐Ying Shih, Kin‐Shing Lun, Tak‐Cheung Yung, Sabrina Tsao

“…The diagnosis of BrS was established with a type 1 ECG pattern detected spontaneously or induced by flecainide, excluding secondary causes. …”
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Malarial pigment-induced lipoperoxidation, inhibited motility and decreased CCR2 and TNFR1/2 expression on human monocytes by Oleksii Skorokhod, Valentina Barrera, Elena Valente, Daniela Ulliers, Koji Uchida, Evelin Schwarzer

“…Objective: Malaria remains an important life-threatening disease that provokes a complex immune response, marked by an initial immune boost followed by long-term suppression, warranting further study. …”
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Can We Reduce the Diagnostic Burden of Sleep Disorders? A Single-Centre Study of Subjective and Objective Sleep-Related Diagnostic Parameters by Tadas Vanagas, Domantė Lipskytė, Jovita Tamošiūnaitė, Kęstutis Petrikonis, Evelina Pajėdienė

“…<i>Results:</i> We report the corresponding sensitivity and specificity values: the Epworth Sleepiness Scale (ESS)—73.2% and 44.1% for detecting severe obstructive sleep apnoea and 87.1% and 76.8% for detecting hypersomnia; the Insomnia Severity Index (ISI)—77.2% and 63.3% for detecting insomnia; the Berlin Questionnaire (BQ)—67.8% and 68.8% for detecting obstructive sleep apnoea; the Ullanlina Narcolepsy Scale (UNS)—84.4% and 58.9% for detecting hypersomnia; the Innsbruck REM Sleep Behaviour Disorder Inventory (RBD-I)—93.3% and 52.5% for detecting RBD; the REM Sleep Behaviour Disorder Single-Question Screen (RBD1Q)—73.3% and 81.0% for detecting RBD; and the Paris Arousal Disorder Severity Scale (PADSS)—57.5% and 90.5% for detecting parasomnia. …”
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Rare Presentation of Vulvar Carcinoma: A Case Report by Aishwarya Balwant Badkhal, Bhushan Jajoo, Tanu Pradhan, Anilreddy Cherukula, Pankaj Katariya

“…Author presents a case of a 52-year-old female with a painful lesion on the right vulvar region, initially misdiagnosed as a dermatological condition. …”
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Atypical clinical presentation associated with Castleman disease: a case report and review of the literature by Weiwei Hu, Yuke Kong, Bianxiang Hu, Jun Ai, Peng Zhang

“…Enhancing awareness of iMCD among healthcare providers is essential for early detection and effective management.…”
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An atypical presentation of autoimmune hepatitis with delayed menarche in a Nigerian adolescent: a case report by Promise Udoka Asogwa, Bruno Basil, Winifred Njideka Adiri, Nelson Ugwu, Gideon Ekene Anigbo, Evaristus Offia, Casmir Orjioke

“…She had no history of jaundice and abdominal pain, and she had no significant past medical history. She was initially misdiagnosed, delaying appropriate management. …”
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European strategies in the screening of biliary atresia: a scoping review by Barbara E Wildhaber, Ana Maria Calinescu

“…Several European countries have also begun implementing BA screening initiatives, although slowly. In this study, we evaluate BA screening strategies across Europe.Methods Published data, after having performed a scoping review, as well as internet searches were analyzed. …”
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Study on the fusion of improved YOLOv8 and depth camera for bunch tomato stem picking point recognition and localization by Guozhu Song, Jian Wang, Rongting Ma, Yan Shi, Yaqi Wang

“…This research meets the needs of string tomato picking robots in fruit stalk target detection and provides strong support for the development of string tomato picking technology.…”
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6-Gingerol protects cardiocytes H9c2 against hypoxia-induced injury by suppressing BNIP3 expression by Qi Ren, Shaojun Zhao, Changjie Ren

“…For moderating cardiomyocytes loss, we initially probed the cyto-protection effects of 6-Gingerol (6 G), meanwhile, its potential mechanisms associated with BNIP3 were elucidated in our studies.Methods We pretreated cardiomyocytes H9c2 cells with 6 G at different concentrations (0–100 μM) before exposure to hypoxia. …”
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Effects of the October 2024 Storm over the Global Ionosphere by Krishnendu Sekhar Paul, Haris Haralambous, Mefe Moses, Sharad C. Tripathi

“…Furthermore, storm-induced equatorial plasma bubbles (EPBs) were observed over Southeast Asia, initiated by enhanced PPEFs during the main phase and suppressed during recovery, consistent with super EPB development mechanisms.…”
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Strategy of Russian Military Cooperation with the Countries of the Arab Region by A. A. Zhilchenko, M. N. Pasko

“…Furthermore, the article elucidates the principal risks inherent in military cooperation among nations at present, highlighting concerns regarding the possible manipulation of military-technical cooperation mechanisms to serve as leverage in furthering the geopolitical aspirations of specific stakeholders.In conclusion, the study posits forward-looking trajectories for bolstering bilateral relations, both sectorally and geographically. These include initiatives such as expanding licensing, leasing, offset transactions, and technology transfer initiatives; advocating for fifth-generation fighter aircraft and long-range radar detection and control systems, leveraging Industry 4.0 technologies; and prioritizing the training of foreign specialists.…”
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The relationship between protein-energy wasting and cognitive impairment in patients receiving maintenance hemodialysis by Jun Liu, Jingfang Wan, Kehong Chen, Yani He, Weiwei Zhang, Jiyuan Luo, Dan Li

“…ObjectivesTo investigate the relationship between protein-energy wasting (PEW) and cognitive impairment (CI) in patients undergoing maintenance hemodialysis (MHD).MethodsA total of 185 patients undergoing MHD between June 2020 and April 2022 were initially recruited. Among the initially recruited patients, 25 patients were excluded, and 160 patients were finally involved in this study. …”
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Diagnostic accuracy of combined pleural fluid adenosine deaminase and lymphocyte-to-neutrophil ratio versus CBNAAT/TrueNat in suspected tubercular pleural effusion patients by Indraneel Bose, Jaydip Deb, Shilpi Adhikary, Dibyendu Saha

“…In a high-tuberculosis (TB)-prevalence regions, markedly elevated pleural fluid adenosine deaminase (ADA) combined with strong clinical suspicion can justify treatment initiation. In low-prevalence areas, ADA retains a high negative predictive value (NPV) but its positive predictive value declines. …”
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Endotheliopathy in systemic sclerosis: from endothelium-dependent vasodilation to the dysfunction of the vascular reserve, is the paradise lost? by Giulia Bandini, Silvia Bellando Randone, Mirko Manetti, Lorenzo Dagna, Marco Matucci Cerinic, Alberto Moggi Pignone

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“The silent killer”: a case series on pulmonary embolisms by Sharan BOSE, P.K. ANANTHAKUMAR, K.V. RAJALAKSHMI, Jibin SIMON

“…Thus it is imperative for clinicians to have a comprehensive understanding of the various presentations possible, to allow timely detection and prevent delays in the potentially lifesaving therapy that must be initiated.…”
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