Type 2 diabetes mellitus and multiple chronic diseases by Nailya S. Asfandiyarova, Olga V. Dashkevich, Natalya V. Doroshina, Ekaterina I. Suchkova

“…Results: Type 2 DM was detected in 407 patients with MCD (18.1%; male:female, 1:2.53). …”
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Feasibility of decentralised deployment of Xpert MTB/RIF test at lower level of health system in India. by Neeraj Raizada, K S Sachdeva, Achuthan Sreenivas, Bhavin Vadera, R S Gupta, Malik Parmar, Shubhangi Kulsange, Ameet Babre, Rahul Thakur, Christen Gray, Ranjani Ramachandran, Umesh Alavadi, Mayank Ghedia, Balasangameshwara Vollepore, Puneet Dewan, Catharina Boehme, C N Paramsivan

“…<h4>Background</h4>Xpert MTB/RIF is an automated cartridge-based nucleic acid amplification test that has demonstrated its potential to detect tuberculosis and rifampicin resistance with high accuracy. …”
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Exploring the associations between gut microbiota composition and SARS-CoV-2 inactivated vaccine response in mice with type 2 diabetes mellitus by Long Liu, Xianzhen He, Jiaqi Wang, Moran Li, Xiuli Wei, Jing Yang, Gong Cheng, Weixing Du, Zhixin Liu, Xiao Xiao

“…Notably, the initial IgG response positively correlated with fecal microbiota alpha diversity pre-vaccination. …”
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Prediction of colorectal cancer diagnosis based on circulating plasma proteins by Silvia Surinova, Meena Choi, Sha Tao, Peter J Schüffler, Ching‐Yun Chang, Timothy Clough, Kamil Vysloužil, Marta Khoylou, Josef Srovnal, Yansheng Liu, Mariette Matondo, Ruth Hüttenhain, Hendrik Weisser, Joachim M Buhmann, Marián Hajdúch, Hermann Brenner, Olga Vitek, Ruedi Aebersold

“…Abstract Non‐invasive detection of colorectal cancer with blood‐based markers is a critical clinical need. …”
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The universal accumulation of p-aminophenol during the microbial degradation of analgesic and antipyretic acetaminophen in WWTPs: a novel metagenomic perspective by Chao-Fan Yin, Piaopiao Pan, Tao Li, Xin Song, Ying Xu, Ning-Yi Zhou

“…Results Among the water samples from 20 WWTPs across China, acetaminophen was detected from 19 samples at concentrations ranging from 0.06 to 29.20 nM. …”
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Emergence of Bluetongue Virus Serotype 3 in Portugal (2024) by Sílvia C. Barros, Ana Margarida Henriques, Fernanda Ramos, Tiago Luís, Teresa Fagulha, André Magalhães, Inês Caetano, Fábio Abade dos Santos, Filipa O. Correia, Carlos C. Santana, Ana Duarte, Ruben Villalba, Margarida D. Duarte

“…Within one month of these initial detections, additional cases in both sheep and cattle were reported in neighbouring districts, indicating the virus rapid spread within the region. …”
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Retinal fundus imaging-based diabetic retinopathy classification using transfer learning and fennec fox optimization by Indresh Kumar Gupta, Shruti Patil, Supriya Mahadevkar, Ketan Kotecha, Awanish Kumar Mishra, Joel J.P.C. Rodrigues

“…Elevated blood glucose levels damage the retina's microvasculature, initiating the condition. Early detection through retinal fundus imaging, supported by timely analysis and treatment, is critical for managing DR effectively. …”
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Prevalence of ESBL-Resistant Genes in Birds in Italy—A Comprehensive Review by Muhammad Tahir Sarfraz Khan, Nicoletta Formenti, Giovanni Tosi, Flavia Guarneri, Federico Scali, Muhammad Kashif Saleemi, Eugenio Monti, Giovanni Loris Alborali

“…This review aims to assess the prevalence of ESBL-producing <i>E. coli</i>, <i>Salmonella</i> and <i>Klebsiella</i> phenotypically and genotypically in Italian poultry, identifying the most common genes, detection methods and potential information gaps. An initial pool of 1462 studies found in scientific databases (Web of Sciences, PubMed, etc.) was screened and 29 were identified as eligible for our review. …”
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A prospective cohort study of the SEARCH integrated HIV/hypertension community health worker‐led intervention in rural Kenya and Uganda by Matthew D. Hickey, Asiphas Owaraganise, Sabina Ogachi, Helen Sunday, Colette Aoko, Norton Sang, George Agengo, Jane Kabami, Elijah Kakande, Erick Wafula Mugoma, Josh Schwab, Nicole Sutter, Douglas Black, Anthony Muiru, Gabriel Chamie, Maya L. Petersen, Laura B. Balzer, Elizabeth A. Bukusi, Diane V. Havlir, Moses R. Kamya, James Ayieko

“…We hypothesised that Ministry of Health (MoH) community health workers (CHWs) could improve severe hypertension detection and treatment through an integrated hypertension/HIV intervention. …”
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JWST/NIRCam Coronagraphic Search for Hidden Planets in the HD 163296 Protoplanetary Disk by Taichi Uyama, Luca Ricci, Marie Ygouf, Sean Andrews, Sara Gallagher, Jane Huang, Andrea Isella, Dimitri Mawet, Laura M. Pérez, Massimo Robberto, Garreth Ruane, Shangjia Zhang, Zhaohuan Zhu

“…Our F410M observations did not detect the putative planets at the predicted locations of the ALMA velocity kinks, but they did detect a point-like source candidate at a separation of $\approx 0\mathop{.}…”
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Early diagnosis of mineral and bone disorders in patients with diabetic kidney disease on the background of type 2 diabetes by V.M. Yerokhovych, O.V. Karpenko, I.A. Paliienko, N.M. Kobyliak, M.I. Bobryk, L.V. Shuliarenko, O.A. Rudenko, D.V. Kyriienko, M. Bolanowski, Y.I. Komisarenko

“…Conclusions. Early detection of bone mineral disorders in diabetic kidney disease is important to increase the efficiency of managing patients with type 2 diabetes and timely treatment, prevention of cardiovascular complications and bone metabolism disorders…”
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Metastatic recurrence in women diagnosed with non-metastatic breast cancer: a systematic review and meta-analysis by Eileen Morgan, Colette O’Neill, Richa Shah, Oliver Langselius, Yaqi Su, Clara Frick, Hanna Fink, Aude Bardot, Paul M. Walsh, Ryan R. Woods, Lou Gonsalves, Jan F. Nygård, Serban Negoita, Esmeralda Ramirez-Pena, Karen Gelmon, Nicoleta Antone, Miriam Mutebi, Sabine Siesling, Fatima Cardoso, Julie Gralow, Isabelle Soerjomataram, Melina Arnold

“…Conclusions Higher proportions of metastatic recurrence in patients initially diagnosed at an advanced stage and in earlier calendar period emphasises the importance of early detection and treatment advancements. …”
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Neutralizing antibody test supports booster strategy for young individuals after SARS-CoV-2 Omicron breakthrough by Yichuan Yao, Yunru Yang, Qiqin Wu, Mengyao Liu, Wei Bao, Qiutong Wang, Meijun Cheng, Yunuo Chen, Yiting Yu, Yuan Cai, Mei Zhang, Jingxue Yao, Hongliang He, Changjiang Jin, Changcheng Zheng, Tengchuan Jin, Dali Tong

“…Abstract Background The SARS-CoV-2 Omicron variant, since its initial detection, has rapidly spread across the globe, becoming the dominant strain. …”
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Multilayer analysis of ethnically diverse blood and urine biomarkers for breast cancer risk and prognosis by Jia Feng, Xing Qi, Chen Chen, Baolin Li, Min Wang, Xuelong Xie, Kailan Yang, Xuan Liu, Rui min Chen, Tongtong Guo, Jinbo Liu

“…Subsequently, utilizing clinical laboratory detection data from multiple regions in China, we performed differential analyses and survival assessments on these potential biomarkers to evaluate their clinical relevance and utility. …”
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Determining the Impact of Histology on the Incidence, Pattern, and Timing of Recurrences in Patients with Renal Cell Carcinoma: A Pooled Analysis from the SORCE and ASSURE Trials by Bhavna Oza, Eleni Frangou, Tim Eisen, Grant D. Stewart, Axel Bex, David Harrison, Mahesh K.B. Parmar, Ruth Langley, Duncan Gilbert, Angela Meade

“…Multivariable Cox regression models evaluated overall survival by histology, adjusting for initial relapse location and other important clinical factors. …”
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Advancing CH₄ and N₂O retrieval strategies for NDACC/IRWG FTIR observations with the support of airborne in situ measurements by I. Ortega, J. W. Hannigan, B. C. Baier, K. McKain, D. Smale

“…Ground-based high-resolution Fourier-transform infrared (FTIR) observations, employed by collaborative international initiatives like the Infrared Working Group (IRWG) within the Network for the Detection of Atmospheric Composition Change (NDACC), play a vital role in retrieving the atmospheric amounts of these gases. …”
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Identification of positive selection signatures associated with milk and composition traits in Murciano-Granadina and Barki by Hossein Mohammadi, amir hossien khaltabadi farahani, Mohammad Hossein Moradi

“…The selection of animals by humans left detectable signatures on the genome of modern goat. …”
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Interferon-stimulated circHOMER1 attenuates antiviral innate immunity by Ao Zhang, Ranran Yao, Shijin Geng, Haiying Wang, Rong-Chun Tang, Hengxiang Yu, Rui Xu, Hong-Yan Chen, Yunxuan Zhou, Lan Zhang, Jun Zhang

“…ABSTRACT In an initial screening of virus-induced differentially expressed circRNAs, circHOMER1 was significantly upregulated. …”
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Evaluating glial and neuronal blood biomarkers GFAP and UCH-L1 as gradients of brain injury in concussive, subconcussive and non-concussive trauma: a prospective cohort study by Mark R Zonfrillo, Linda Papa, Robert D Welch, Lawrence M Lewis, Carolina F Braga, Ciara N Tan, Neema J Ameli, Marco A Lopez, Crystal A Haeussler, Diego Mendez Giordano, Philip A Giordano, Jose Ramirez, Manoj K Mittal

“…However, for UCH-L1, there were no significant differences between concussion patients and head trauma controls (p=0.894) and between body trauma and head trauma controls in children. The AUC for initial GFAP levels to detect concussion was 0.80 (0.73–0.87) in children and 0.76 (0.71–0.80) in adults. …”
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The efficacy and safety of divozilimab in patient with systemic sclerosis: 48-week results of the randomized double-blind placebo-controlled phase III clinical study LIBERIUS by L. P. Ananyeva, M. N. Starovoytova, I. Z. Gaydukova, G. V. Lukina, E. V. Zonova, L. V. Eliseeva, G. F. Fatkhullina, D. I. Abdulganieva, D. G. Krechikova, T. V. Kropotina, O. B. Nesmeyanova, I. B. Vinogradova, E. S. Zhugrova, L. V. Ivanova, N. E. Nikulenkova, O. R. Ziganshin, T. V. Plaksina, M. V. Zlobin, Yu. Yu. Grabovetskaya, N. F. Soroka, O. B. Ershova, T. V. Povarova, O. N. Anoshenkova, A. A. Lutckii, A. V. Zinkina-Orikhan, Yu. N. Linkova, E. A. Fokina, A. A. Porozova, P. S. Pukhtinskaia, A. V. Eremeeva

“…The most were female; the median duration of the disease was about 3–4 years. The initial value of the mRSS was 14 and 13 points in DIV and PBO groups, respectively. …”
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