Editorial: Current advances in anti-infective strategies by Asmaa M. Salih Almohaidi, Fikrat M. Hassan, Hussin Rothan

“…Since the onset of the most recent pandemic, COVID-19, which was initially identified as a worldwide health crisis, numerous countries experienced profound disruptions in their healthcare systems. …”
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Oral mucosal lesions triage via YOLOv7 models by Yu Hsu, Cheng-Ying Chou, Yu-Cheng Huang, Yu-Chieh Liu, Yong-Long Lin, Zi-Ping Zhong, Jun-Kai Liao, Jun-Ching Lee, Hsin-Yu Chen, Jang-Jaer Lee, Shyh-Jye Chen

“…Background/purpose: The global incidence of lip and oral cavity cancer continues to rise, necessitating improved early detection methods. This study leverages the capabilities of computer vision and deep learning to enhance the early detection and classification of oral mucosal lesions. …”
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Monitoring method⁃based guided wave for hole-edge crack in key attachment structure of helicopter by WANG Huaji, SHI Liming, DAI Yushan, QIU Lei

“…ObjectiveThe harsh operational environment of helicopters renders their structures highly susceptible to the initiation and propagation of hole-edge cracks around bolt holes, thereby compromising structural integrity and load-bearing capacity. …”
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Type IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophila. by Sunny Shin, Christopher L Case, Kristina A Archer, Catarina V Nogueira, Koichi S Kobayashi, Richard A Flavell, Craig R Roy, Dario S Zamboni

“…The immune system must discriminate between pathogenic and nonpathogenic microbes in order to initiate an appropriate response. Toll-like receptors (TLRs) detect microbial components common to both pathogenic and nonpathogenic bacteria, whereas Nod-like receptors (NLRs) sense microbial components introduced into the host cytosol by the specialized secretion systems or pore-forming toxins of bacterial pathogens. …”
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Feature Fusion for Improved Skin Cancer Diagnosis Using Support Vector Machines by ali fahim

“… the early detection and successful treatment of skin cancers, a potent form of cancer, calls for the use of sophisticated diagnostic instruments. …”
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eDNA-Based Survey of Fish Species in Water Bodies Using Loop-Mediated Isothermal Amplification (LAMP) for Application of Developing Automatic Sampler by Nivedhitha Jothinarayanan, Chau Ha Pham, Frank Karlsen, Lars Eric Roseng

“…The most effective combination for successful species monitoring may be the collection of eDNA or biological traces collected by nanofiltration followed by LAMP-based species detection initiatives. Here, we used LAMP analysis to detect the eDNA of <i>Esox lucius</i> (Northern Pike), <i>Anguilla anguilla</i> (European Eel), and <i>Salmo salar</i> (Atlantic Salmon) in Borre Lake and in the Drammen River. …”
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Survey for Highly Pathogenic Avian Influenza from Poultry in Two Northeastern States, Nigeria by Ibrahim Waziri Musa, Paul Ayuba Abdu, Anthony Kojo Bedu Sackey, Sunday Blessing Oladele

“…These results and other poultry diseases similar to AI observed in this study could invariably affect avian influenza early detection, reporting, and control. We recommend strong policy initiatives towards poultry farmers’ attitudinal change and increasing efforts on awareness of the implications of future HPAI outbreaks in Nigeria.…”
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Monitoring method⁃based guided wave for hole-edge crack in key connection structure of helicopter by WANG Huaji, SHI Liming, DAI Yushan, QIU Lei

“…The harsh operational environment of helicopters renders their structures highly susceptible to the initiation and propagation of hole-edge cracks around bolt holes, thereby compromising structural integrity and load-bearing capacity. …”
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Three-Dimensional Reconstruction of Road Structural Defects Using GPR Investigation and Back-Projection Algorithm by Lutai Wang, Zhen Liu, Xingyu Gu, Danyu Wang

“…This paper proposes a three-dimensional (3D) reconstruction method for GPR images, integrating the back-projection (BP) imaging algorithm to accurately determine the size, location, and other parameters of road structural defects. Initially, GPR detection images were preprocessed, including direct wave removal and wavelet denoising, followed by the application of the BP algorithm to effectively restore the defect’s location and size. …”
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A Deep Transfer Learning-Based Visual Inspection System for Assembly Defects in Similar Types of Manual Tool Products by Hong-Dar Lin, Hsiang-Ling Wu, Chou-Hsien Lin

“…This study introduces an advanced inspection system for manual tool assembly, focusing on defect detection and classification in flex-head ratchet wrenches as a modern alternative to traditional inspection methods. …”
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The story of elimination of visceral leishmaniasis (kala-azar) in India-Challenges towards sustainment. by Shyam Sundar

“…Periodic updates of health personnel, community awareness, and continued availability of the theragnostics are important steps for early detection and containment of an outbreak.…”
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Features of the course and therapy of HIV infection in children at different stages of the disease by J. C. Hakizmana, E. B. Yastrebova, V. N. Timchenko, D. A. Gusev, O. V. Bulina

“…The severity of the clinical manifestations of HIV infection, the levels of CD4-lymphocytes and HIV RNA in the blood directly depend on the period of detection and the initiation of ART  in children. The inclusion of human recombinant interferon alpha-2b with antioxidants (Viferon rectal suppositories) in the etiopathogenetic therapy of comorbid herpes virus diseases (EBV-mononucleosis, a generalized form of  CMV infection) is effective and safe.…”
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MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer by Shamima Afrin Ruma, Rufus Vinod, Shruti Jain, Kaisa Huhtinen, Johanna Hynninen, Janne Leivo, Kim Pettersson, Karin Sundfeldt, Kamlesh Gidwani

“…Abstract Glycosylation changes of circulating proteins carrying the CA19-9 antigen may offer new targets for detection methods to be explored for the diagnosis of epithelial ovarian cancer (EOC). …”
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Early and Very Early Post-Transcatheter Aortic Valve Implantation Infective Endocarditis: Imaging Challenges by Nikoleta Hadjigeorgiou, Despo Melanarkiti, Theodora Eleni Plakomyti, Vasileios Demou, Vasileios Giannakopoulos, Chariton Sapouridis, Angeliki Mouzarou

“…However, the early detection of IE following TAVI poses significant diagnostic challenges. …”
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Continuous versus intermittent noninvasive blood pressure measurement in patients with shock in prehospital emergency medicine – a single-center prospective pilot trial by Stephan Katzenschlager, Raphael Heck, Nikolai Kaltschmidt, Frank Weilbacher, Markus A. Weigand, Erik Popp, Maximilian Dietrich

“…Abstract Background Shock is a critical and potentially life-threatening clinical state characterized by circulatory insufficiency and impaired micro- and macrocirculation. Rapid detection and initiation of therapy are essential for patient outcomes. …”
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Multifrequency Behaviour of the Gamma-Ray Binary System PSR B1259-63: Modelling the FERMI Flare by Brian van Soelen, Pieter J. Meintjes

“…A summary is also presented of the various models put forward to explain the Fermi "flare" detected in 2011. Initial results are presented of a new turbulence driven model to explain the GeV observations.…”
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Exposure to high altitude leads to disturbances in host metabolic homeostasis: study of the effects of hypoxia-reoxygenation and the associations between the microbiome and metabol... by Qin Zhao, Doudou Hao, Siyu Wang, Siyuan Chen, Chaohua Zhou, Chen Fan, Qian Su, Wenting Huang, Jiaxin Liu, Qingquan Kong, Yunhong Wu, Zeng He

“…Distinct differences in amino acid, lipid, energy, immune, cofactor, and vitamin metabolism pathways were detected between high- and low-altitude populations, with a partial recovery of disparities during reoxygenation. …”
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Strongyloides stercoralis combined with concurrent multiple pathogens infections in an immunosuppressed patient: a case report by Jingchun Fang, Jingchun Fang, Huimin Fang, Huimin Fang, Penghao Guo, Yaqin Peng, Peisong Chen

“…People with underlying diseases and weakened immunity are prone to develop severe conditions after infection with Strongyloides stercoralis.Case presentationWe report an immunocompromised patient in whom the pathogen was initially not detectable using traditional parasitic detection techniques. …”
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Perinatal stroke (a case report) by K. V. Makeeva, A. A. Makarova, A. A. Usynina

“…We report a case of fetal stroke in а newborn. In the patient, initial minimal clinical signs were accompanied by pathological changes detected by visual diagnostic methods and electroencephalography. …”
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Effect of GBA Mutations on Phenotype of Parkinson’s Disease: A Study on Chinese Population and a Meta-Analysis by Yuan Zhang, Qi-ying Sun, Yu-wen Zhao, Li Shu, Ji-feng Guo, Qian Xu, Xin-xiang Yan, Bei-sha Tang

“…Whether the clinical manifestations of PD patients with or without GBA mutations are different has still not reached a consensus. We firstly detected the GBA mutation L444P in 1147 Chinese PD patients and simultaneously evaluated their corresponding clinical data. …”
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