Characteristics of immune-active and immune-silent phenotypes of early-stage cervical carcinoma as revealed by transcriptome sequencing by O. V. Kurmyshkina, P. I. Kovchur, T. O. Volkova

“…Overall, the existence and detectability of different transcriptomic immune-based phenotypes of invasive CeCa at its initial stages of progression is shown, which may provide new options to broaden the knowledge and applicability of target and immune anti-cancer therapy.…”
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Quid du port romain estuarien de Barzan (Charente-Maritime) ? by Vivien Mathé, Laurence Tranoy, Marion Druez, François Lévêque, Vincent Miailhe, Frédéric Pouget

“…Several anomalies were thus detected on the opposite edges of the basin. One of these, exhibiting a longitudinal shape, could correspond to a quay. …”
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Perioperative hemodynamic status in children with acquired hydrocephalia by Snisar V.I., Skliar V.V., Lisivets V.I.

“…A multifactorial analysis has shown that HR incidence increased after premedication in TIVA group by 8.6% versus 5.8% in IA group from initial value. There was no sighnificant differences between groups (р>0.05). …”
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THE USE OF HPLC AS A TOOL FOR NEONATAL CORD BLOOD SCREENING OF HAEMOGLOBINOPATHY - A VALIDATION STUDY by A. Al-Madhani, Anil Pathare, Salam Alkindi

“…Additionally, amongst 151 subjects, 72 subjects were studied in the initial study by Hb Bart’s quantitation using aalpha thalassaemia short program at birth. …”
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Optimization of variable temperature fermentation process of koumiss and its quality analysis by GUO Huanhuan, GOU Yongzhen, LI Jie, NIU Xiyue, XU Qian, CHEN Shenghuizi, REN Qing, QU Yebo

“…The results indicated that the optimal variable temperature fermentation process of koumiss was inoculum 4%, Lactobacillus helveticus MX6 and Kluyveromyces marxianus ML25 inoculation ratio 1∶2, initial fermentation temperature 37 ℃, initial fermentation time 6 h and variable temperature fermentation time 30 h, the total fermentation time was 12 h shorter than the mainstream fermentation process. …”
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Comparative Analysis of Microbial Growth in Raw and Pasteurized Cow and Camel Milk During Chilled Storage by Mohammed Aladhadh, Emad M. Abdallah

“…Pasteurized samples showed no S. aureus or Lactobacillus spp. growth, confirming pasteurization’s effectiveness. The study detected no fungal or pathogenic contamination. In conclusion, camel milk exhibited higher initial bacterial counts and slower bacterial growth than cow milk, but supported more sustained microbial proliferation over time. …”
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Clinical and Laboratory Characteristics of Children with Chronic Idiopathic Thrombocytopenic Purpura by Milica Cekerevac, Jelena Pantovic, Marija Medovic, Nebojsa Igrutinovic, Sanja Knezevic, Bojana Markovic, Isidora Mihajlovic, Zeljko Todorovic, Tijana Maksic, Natalija Vitosevic, Suzana Zivojinovic, Jelena Cekovic Djordjevic, Tijana Prodanovic, Rasa Medovic

“…Twenty-five percent of patients were resistant to initial therapy. <i>Helicobacter pylori</i> was detected in 20%, 70% had higher levels of lactate dehydrogenase (LDH), three patients had sufficient serum vitamin D levels, splenomegaly was found in 25%, and accessory spleen in 14% of patients. …”
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Robot-assisted laparoscopic ureteropelvic junction plasty in children using the da Vinci Xi robotic system: a Russian first experience by V. V. Sizonov, A. G. Makarov, S. M. Pakus, D. G. Kvaratskhelia, E. V. Orlova, S. G. Piskunova, M. I. Kogan

“…The present study introduces the initial experience of executing robot-assisted laparoscopic pyeloplasty (RALP) employing the da Vinci Xi robotic system.Objective. …”
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Insights from UKCTOCS for design, conduct and analyses of large randomised controlled trials by Usha Menon, Aleksandra Gentry-Maharaj, Matthew Burnell, Sophia Apostolidou, Andy Ryan, Jatinderpal K Kalsi, Naveena Singh, Lesley Fallowfield, Alistair J McGuire, Stuart Campbell, Steven J Skates, Anne Dawnay, Mahesh Parmar, Ian J Jacobs

“…We faced issues with regard to our initial trial design and the way we planned to analyse the data. …”
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Pathogenetic mechanisms of nephropathy formation in type 1 diabetes mellitus by L. V. Kutsenko, I. V. Zorin, A. A. Vyalkova

“…Modern screening tests can detect diabetic nephropathy only from the 1st clinical stage — the stage of microalbuminuria, omitting initial structural and functional disorders which develop long before the increase in albumin excretion. …”
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Characterization of infectious salmon anaemia virus survival and infectivity in seawater by Simon Chioma Weli, Marit Måsøy Amundsen, Ole Bendik Dale, Sonal Jayesh Patel

“…Survival was dependent on temperature and on initial concentrations, and our findings indicate that low initial numbers of virus particles combined with high incubation temperature reduces survival and infectivity. …”
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Enhancing the reverse transcriptase function in Taq polymerase via AI-driven multiparametric rational design by Yulia E. Tomilova, Nikolay E. Russkikh, Igor M. Yi, Elizaveta V. Shaburova, Viktor N. Tomilov, Galina B. Pyrinova, Svetlana O. Brezhneva, Olga S. Tikhonyuk, Nadezhda S. Gololobova, Dmitriy V. Popichenko, Maxim O. Arkhipov, Leonid O. Bryzgalov, Evgeniy V. Brenner, Anastasia A. Artyukh, Dmitry N. Shtokalo, Dmitry N. Shtokalo, Dmitry N. Shtokalo, Denis V. Antonets, Mikhail K. Ivanov, Mikhail K. Ivanov

“…These candidates, along with the wild type, were assessed in the wet lab for multiple properties to establish an initial training dataset. 2) Using embeddings of Taq polymerase variants generated by a protein language model, we trained a Ridge regression model to predict multiple enzyme properties. …”
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Listract Test: A Standardized Assessment Method for Isolated Lisfranc Instability in Cadaver Models by Vasundhara Mathur, David Osei-Hwedieh, Sayyed Hadi Sayyed Hosseinian, Fernando Raduan, Philip B Kaiser, Gregory R Waryasz, Lorena Bejarano-Pineda, John Y Kwon, Hamid Ghaednia, Soheil Ashkani-Esfahani

“…Aim and background: Ligamentous Lisfranc injuries are challenging to detect, with 20–40% of them remaining undiagnosed or misdiagnosed at initial presentation. …”
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Investigating the influence of Diadematidae scuticociliatosis on host microbiome composition by Brayan Vilanova-Cuevas, Christopher M. DeRito, Isabella T. Ritchie, Christina A. Kellogg, James S. Evans, Alizee Zimmerman, Stacey M. Williams, Marilyn Brandt, Moriah Sevier, Samuel Gittens, Kayla A. Budd, Matthew Warham, William C. Sharp, Gabriel A. Delgado, Alwin Hylkema, Kimani Kitson-Walters, Jean-Pascal Quod, Mya Breitbart, Ian Hewson

“…Tissue samples from both grossly normal and abnormal Diadema antillarum were collected in the field during the initial assessment of the DSc causative agent and from an experimental challenge of DScPc culture on aquacultured D. antillarum. …”
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Mycotoxin Challenge in Dairy Cows: Assessment of the Efficacy of an Anti-Mycotoxin Agent by Adopting an In Vitro Rumen Simulation Method by Erica Fiorbelli, Marco Lapris, Michela Errico, Antonella Della Badia, Insaf Riahi, Gabriele Rocchetti, Antonio Gallo

“…Therefore, the objective of this study was to evaluate the in vitro ruminal initial sequestration (weak binding) and subsequent desorption (strong binding) of an anti-mycotoxin agent based on a mixture of adsorbing material, turmeric and milk thistle extracts and yeast-based components to adsorb or bio-convert aflatoxins (AF), fumonisins B1 and B2 (FB), trichothecene deoxynivalenol (DON), T-2 and HT-2 toxins, and zearalenone (ZEN). …”
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Dynamic Monitoring of Circulating Tumor DNA to Predict the Risk of Non In Situ Recurrence of Postoperative Glioma: A Prospective Cohort Study by Guangzhong Guo, Ziyue Zhang, Jiubing Zhang, Dayang Wang, Sensen Xu, Shuang Wu, Kaiyuan Deng, Yage Bu, Zhiyuan Sheng, Jinliang Yu, Yushuai Gao, Zhaoyue Yan, Ruijiao Zhao, Meiyun Wang, Tianxiao Li, Xingyao Bu

“…Conclusions In glioma patients undergoing primary surgery, dynamic monitoring of ctDNA and genotyping can be used for early risk stratification, efficacy monitoring, and early recurrence detection, and provide a basis for clinical research to evaluate early therapeutic intervention.…”
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PRECISION MEDICINE IN CLL: TREATMENT BASED ON MOLECULAR PROFILES by Esra Terzi Demirsoy

“…Flow cytometry, PCR, and NGS are the primary methods employed to detect MRD. The threshold for MRD detection remains a subject of debate. …”
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Development and validation of a machine learning model for predicting vulnerable carotid plaques using routine blood biomarkers and derived indicators: insights into sex-related ri... by Yimin E, Zhichao Yao, Maolin Ge, Guijun Huo, Jian Huang, Yao Tang, Zhanao Liu, Ziyi Tan, Yuqi Zeng, Junjie Cao, Dayong Zhou

“…Abstract Background Early detection of vulnerable carotid plaques is critical for stroke prevention. …”
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Dynamics of level of the tumor-associated marker SCCA in neoadjuvant superselective intra-arterial chemotherapy in patients with cervical squamous cell carcinoma by N. S. Sergeeva, N. V. Marshutina, Kh. R. Maltsagova, T. A. Karmakova, I. I. Alentov, S. V. Mukhtarulina, T. I. Dezhkina, A. G. Rerberg, A. D. Kaprin

“…SCCA level after 2 courses decreased in all patients with initially increased its level, while the proportion of SCCA-positive cases decreased from 71.7 to 26.4 %. …”
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Rapid diagnosis of Mycoplasma pneumoniae and prediction of antibiotic resistance by nanopore adaptive sampling by Yunke Sun, Xiaonan Li, Jiale He, Lingguo Zhao, Qingliang Chen, Lei Lei, Jun Chen, Lin Zhong, Guobao Li, Yu Xia, Yanmin Bao, Yingdan Zhang, Liang Yang

“…We then compared the accuracy of detecting pathogens between NNS and NAS and between NAS and real‐time polymerase chain reaction assays. …”
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