Challenging diagnosis and treatment of rare paranasal sinus metastasis from thyroid cancer: a case report and literature review by Jee Hee Yoon, Jee Hee Yoon, Ji Yong Park, Ji Yong Park, A Ram Hong, A Ram Hong, Sung Sun Kim, Hee Kyung Kim, Hee Kyung Kim, Ho-Cheol Kang, Ho-Cheol Kang

“…Lenvatinib therapy was initiated after total thyroidectomy and radioactive iodine (RAI) therapy, achieving stable disease for 29 months. …”
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Can Gut Microbiota Analysis Reveal <i>Clostridioides difficile</i> Infection? Evidence from an Italian Cohort at Disease Onset by Roberto Rosato, Gianluca Quaranta, Giulia Santarelli, Giovanni Fancello, Delia Mercedes Bianco, Francesca Romana Monzo, Stefano Bibbò, Giovanni Cammarota, Maurizio Sanguinetti, Luca Masucci, Flavio De Maio

“…In this study, we examined the composition of the gut microbiota in patients at the time of the initial detection of CDI compared to a control group of CDI-negative individuals, with a focus on identifying potential CDI biomarkers for diagnosis. …”
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Impact of INSAT‐3D land surface temperature assimilation via simplified extended Kalman filter‐based land data assimilation system on forecasting of surface fields over India by Abhishek Lodh, Ashish Routray, Devajyoti Dutta, Vivek Singh, John. P. George

“…The scores for the verification measures, specifically the Probability of Detection (POD), demonstrate a ~15% improvement in both the forecasts for maximum and minimum temperatures. …”
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Molecular Epidemiology of Dengue Viruses in Lao People’s Democratic Republic, 2020–2023 by Cécile Troupin, Kedkeo Intavong, Somphavanh Somlor, Souksakhone Viengphouthong, Sitsana Keosenhom, Thep Aksone Chindavong, Phaithong Bounmany, Longthor Vachouaxiong, Thonglakhone Xaybounsou, Chittaphone Vanhnollat, Phonepadith Khattignavong, Darouny Phonekeo, Bouaphanh Khamphaphongphane, Phonepadith Xangsayarath, Vincent Lacoste, Philippe Buchy, Gary Wong

“…Dengue fever is a widespread mosquito-borne viral disease caused by infections with dengue virus (DENV). Since its initial detection in 1979, the disease has posed a significant public health threat to the Lao People’s Democratic Republic (Lao PDR). …”
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Translation, cultural adaptation, and validation of the HEAR-COMMAND Tool – Arabic: a self-rated ICF-based questionnaire for assessing hearing, communication, and conversation disa... by Razan Alfakir, Mahmoud Hammady, Tahereh Afghah, Mohamed Abd Al-Ghaffar, Mostafa Youssif

“…Content validation of the initial (beta) version was performed to confirm the tool’s relevance and comprehensibility by collecting responses from 30 participants. …”
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Time is health: management of Parkinson’s disease in primary care: a retrospective quantitative study of diagnostic and therapeutic timelines by Sabine Bayen, Xavier Lagon, Charles Cauet, Marc Bayen, Teddy Richebe, Nassir Messaadi, Matthieu Calafiore

“…Abstract Background Parkinson’s disease is a neurodegenerative disorder which can be difficult to diagnose due to the non-specificity of the initial symptoms. The objective of our study was to objectify and quantify the delay of the diagnostic process and to identify the factors that influence it. …”
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Relationship Between Troponin on Presentation and In‐Hospital Mortality in Patients With ST‐Segment–Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Interve... by Brett L. Wanamaker, Milan M. Seth, Devraj Sukul, Simon R. Dixon, Deepak L. Bhatt, Ryan D. Madder, John S. Rumsfeld, Hitinder S. Gurm

“…Of the 14 061 patients included in the cohort, 47.2% had initial troponin levels that were undetectable or within the reference range. …”
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A case of refractory immune checkpoint inhibitor‐induced colitis with Clostridioides difficile infection by Yukito Okura, Katsumasa Kobayashi, Yurina Yamada, Makoto Furuya, Naoki Kitano, Eri Oshina, Mana Matsuoka, Takahito Nozaka, Yoshihiro Tashiro, Ayako Sato, Masato Yauchi, Taichi Matsumoto, Yohei Furumoto, Toru Asano, Seishin Azuma

“…Histopathological examination of colonic mucosa revealed diffuse inflammatory cell infiltration and apoptosis. The initial cytomegalovirus antigen test and C. difficile detection assay results were negative. …”
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Synthesis, structure and properties of N-R-amides and hydrazides of 2-[4-R-5-(theophylline-7ʹ-yl)-1,2,4-triazole-3-ylthio]acetic acid by A. S. Gotsulya

“…Getting investigated amides by two alternative ways of synthesis, it was established that the initial interaction of thiol with 2-chloracetamide proceeds with high yield product of the reaction compared to the reaction between a corresponding ester with ammonia. …”
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Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure. by Leah Mwai, Abdi Diriye, Victor Masseno, Steven Muriithi, Theresa Feltwell, Jennifer Musyoki, Jacob Lemieux, Avi Feller, Gunnar R Mair, Kevin Marsh, Chris Newbold, Alexis Nzila, Céline K Carret

“…Often, stable resistance arises from initial, unstable phenotypes that can be identified in vitro. …”
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Re-exposition to ipilimumab plus nivolumab in metastatic Merkel cell carcinoma by Valerie Glutsch, Patrick Schummer, Matthias Goebeler, Anja Gesierich, Bastian Schilling, Bastian Schilling

“…With a follow-up period ranging from 6.5 to 37.1 months, no PFS event has been detected. ORR for IPI/NIVO re-exposition was equal to that of initial IPI/NIVO treatment.ConclusionIn this retrospective follow-up analysis, we observed a response rate of 67% and long-lasting responses after re-exposition to combined ICI in metastatic MCC patients with progression after initial response or disease control upon their first IPI/NIVO treatment. …”
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Kinematic effects of sensorimotor foot orthoses on the gait of patients with patellofemoral pain—a randomized controlled trial by Steven Simon, Jonas Dully, Oliver Ludwig, Carlo Dindorf, Eva Bartaguiz, Michael Fröhlich, Stephan Becker

“…No significant immediate effects of FOs were detected; however, there were significant interaction effects between the time of measurement and the groups. …”
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Osteodestruction markers and quality of life parameters at pomegara (pamidronate) treatment in multiple myeloma patients with lytic bone lesions by V. V. Lunin, Ye. V. Yurova, O. A. Kudryavtseva, S. V. Minenko, V. V. Ptushkin

“…Statistically significant increasing of integrated quality of life parameter in comparison with initial value is registered by 12th week of treatment (р &lt; 0.05). …”
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Clinical Characteristics of Pregnancy-Associated Central Serous Chorioretinopathy in the Chinese Population by Jia Yu, Lei Li, Chunhui Jiang, Qing Chang, Gezhi Xu

“…The mean BCVA (logarithm of the minimum angle of resolution (logMAR)) at the initial visit was 0.36 ± 0.18 (Snellen 20/45, range 20/100–20/25). …”
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Internal obesity as a risk factor for arterial hypertension by M. A. Druzhilov, T. Yu. Kuznetsova

“…Of the 406 available patients, hypertension was detected in 157 (38,7%), including 72 (31,7%) of the initial age group of 35-45 years and 85 (47,5%) of the initial age group 46-55 years. …”
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STRUCTURE AND PREVALENCE OF PERIODONTIC TISSUE DISEASES IN SMOKERS USING TOBACCO HEATING PRODUCTS by N.B. Kuzniak, I.D. Kiiun, O.M. Soltys, N.V. Vatamaniuk, O.M. Kavchuk

“…The prevalence of GP of the initial severity in the comparative group increased with the age of patients. …”
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Gravitational-wave and Gravitational-wave Memory Signatures of Core-collapse Supernovae by Lyla Choi, Adam Burrows, David Vartanyan

“…In this paper, we calculate the energy, signal-to-noise ratio (SNR), detection range, and angular anisotropy of the matter, matter memory, and neutrino memory gravitational-wave (GW) signatures of 21 three-dimensional initially nonrotating core-collapse supernova (CCSN) models carried to late times. …”
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Gesture recognition for hearing impaired people using an ensemble of deep learning models with improving beluga whale optimization-based hyperparameter tuning by Mohammed Assiri, Mahmoud M. Selim

“…To accomplish that, the GRHIP-EDLIBWO method initially performs image preprocessing using a Sobel filter (SF) to enhance edge detection and extract critical gesture features. …”
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Expression of a humanized viral 2A-mediated lux operon efficiently generates autonomous bioluminescence in human cells. by Tingting Xu, Steven Ripp, Gary S Sayler, Dan M Close

“…Furthermore, the use of self-directed bioluminescent initiation in response to target detection was assessed to determine its amenability towards deployment as fully autonomous sensors. …”
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Proximal Humerus Allogenic Transplant for Treatment of a Complex Proximal Humerus Fracture-Dislocation by Lucas Armada, Pedro Amaro, Raul Alonso, Luís Pires

“…Initial management involved open reduction and internal fixation, but postoperative imaging revealed hardware failure and recurrent shoulder dislocation. …”
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