The role of androgens and global and tissue-specific androgen receptor expression on body composition, exercise adaptation, and performance by Sabrina Tzivia Barsky, Douglas Ashley Monks

“…Here, we summarize the understood mechanisms of action of AR and its interactions with exercise, specifically on outcomes of body composition and muscle function, and the global- and tissue-specific role of AR in regulating skeletal muscle, adipose, and bone morphology. …”
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Multi‐omics integration analysis identifies INPP4B as a T‐cell‐specific activation suppressor by Ting Peng, Qing Fang, Zihao Zhao, Yingjun Chang, Xiangyu Zhao, Cheng Li

“…INPP4B exhibits a T‐cell‐specific expression domain and functions as a T cell activation suppressor. …”
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Piezo1-specific Deletion in Macrophage Protects the Progression of Chronic Inflammatory Bowel Disease in MiceSummary by Yuman Wang, Tianjiao Chu, Chengzhen Meng, Yifei Bian, Jing Li

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Unveiling tissue-specific transcriptional adaptations in iPSC-derived fibroblasts via co-culture systems by Amar J. Azad, Alessandro Bentivogli, Henrike Germar, Dana Wörz, Elena Lizunova, Max J. Cumberland, January Weiner, Sarah Hedtrich

“…However, single-cell deconvolution showed incomplete tissue specification, with iFBs retaining mixed fibroblast subpopulations. …”
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Effectiveness of movement representation techniques in non-specific shoulder pain: a systematic review and meta-analysis by Nuray Alaca, Ali Ömer Acar, Sergen Öztürk

“…Abstract This systematic review and meta-analysis aims to assess the effects of movement representation techniques (MRT) on pain, range of motion, functional outcomes, and pain-related fear in patients with non-specific shoulder pain (NSSP). …”
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Effect of Acupuncture on Functional Connectivity of the Limbic Network in Patients with Knee Osteoarthritis: A Resting State Functional Magnetic Resonance Imaging Study by Wu N, Lou XS, Chang YN, Li JY, Zhang ZH, Hu JH, Fan Y, Feng XD, Yin S

“…However, the central neuroimaging mechanisms underlying acupuncture’s therapeutic effects remain incompletely elucidated. This study investigated brain network differences between KOA patients and healthy controls and further examined the effects of acupuncture on aberrant functional connectivity (FC) within brain networks in KOA patients.Patients and Methods: Blood Oxygenation Level Dependent functional Magnetic Resonance Imaging (BOLD-fMRI) combined with Independent Component Analysis (ICA) was employed to investigate resting-state functional connectivity differences between 45 KOA patients and 15 healthy subjects. …”
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Leukocyte tyrosine kinase functions in pigment cell development. by Susana S Lopes, Xueyan Yang, Jeanette Müller, Thomas J Carney, Anthony R McAdow, Gerd-Jörg Rauch, Arie S Jacoby, Laurence D Hurst, Mariana Delfino-Machín, Pascal Haffter, Robert Geisler, Stephen L Johnson, Andrew Ward, Robert N Kelsh

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Osteocalcin and GPR158: linking bone and brain function by Jingjing Li, Shujie Lou, Xuepeng Bian

“…As a critical receptor for OCN, G protein-coupled receptor 158 (GPR158) facilitates the proliferation, differentiation, and survival of neural cells while directly influencing neurons' structural and functional plasticity, thereby modulating cognitive function. …”
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Testis-specific serine/threonine kinase dTSSK2 regulates sperm motility and male fertility in Drosophila by Ju Peng, Angyang Sun, Jie Zheng, Na Zhang, Xuedi Zhang, Guanjun Gao

“…Abstract Serine/threonine kinases of the TSSK (Testis-Specific Serine/Threonine Kinase) family play crucial roles in spermatogenesis and male fertility across species, but the underlying regulatory mechanism remains incompletely understood. …”
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Prenatal Bisphenol A Exposure Impairs Fetal Heart Development: Molecular and Structural Alterations with Sex-Specific Differences by Alessandro Marrone, Anna De Bartolo, Vittoria Rago, Francesco Conforti, Lidia Urlandini, Tommaso Angelone, Rosa Mazza, Maurizio Mandalà, Carmine Rocca

“…However, the impact of prenatal endocrine disruption on fetal heart development and its sex-specific nature remains incompletely understood. This study investigates the molecular and structural effects of low-dose prenatal BPA exposure on fetal rat hearts. …”
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A method for bi-decomposition of partial Boolean functions by Yu. V. Pottosin

“…The problem of bi-decomposition of a Boolean function is to represent a given Boolean function in the form of a given logic algebra operation over two Boolean functions and so is reduced to specification of these functions. …”
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JCV-specific cell-based assays for PML risk assessment in lupus and multiple sclerosis patients with and without natalizumab by Qi Wu, Qi Wu, Elizabeth A. Mills, Qin Wang, Guangmei Mao, Yang Mao-Draayer, Yang Mao-Draayer

“…The current metrics used to stratify MS patients at risk for PML are incomplete, leading some patients to prematurely discontinue an effective treatment and others to develop PML despite perceived low risk.ObjectiveWe sought to develop a combination of cell-based assays using peripheral blood which can be used to provide a more comprehensive assessment of immune system function and complement existing PML risk metrics.MethodsOur assays measure general and JCV specific responses in CD4+ and CD8+ T cells following antigen stimulation. …”
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B Chromosomes in Wheat: Evolution, Functions and Breeding Potential by Md Mazharul Islam, Deen Mohammad Deepo, Abu Bakar Siddique, Saifullah Omar Nasif, Md Zonayet, Oliul Hassan, Abu Bakar Siddique, Md Arfan Ali

“…The understanding of their origins, composition, and evolutionary history in wheat is still incomplete. Therefore, this review discusses the current knowledge of the genetic makeup of Bs, their functions, their relationship with A chromosomes, and the morphogenetic consequences in the context of wheat.…”
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Lineage-specific microbial protein prediction enables large-scale exploration of protein ecology within the human gut by Matthias A. Schmitz, Nicholas J. Dimonaco, Thomas Clavel, Thomas C. A. Hitch

“…To resolve this, we developed a lineage-specific gene prediction approach that uses the correct genetic code based on the taxonomic assignment of genetic fragments, removes incomplete protein predictions, and optimises prediction of small proteins. …”
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Few-Shot Evaluation of Vision Language Models for Detecting Visual Defects in Autonomous Vehicle Software Requirement Specifications by Nabil Bukhary, Maaz Ahmad, Karim Rashad, Samarth Rai, Salsabeel Shapsough, Yara Kaddoura, Dana Dghaym, Imran Zualkernan

“…Software Requirements Specifications (SRS) are crucial for defining system functionality, constraints, and objectives, particularly in safety-critical applications like autonomous vehicles (AV). …”
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X-inactive-specific transcript: a long noncoding RNA with a complex role in sex differences in human disease by Dan N. Predescu, Babak Mokhlesi, Sanda A. Predescu

“…In this review, we summarize recent knowledge about XIST structure/function correlation and involvement in human disease with focus on XIST abnormal expression in males. …”
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Slow Metabolism–Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone‐Induced Obesity‐Specific Liver Injury by Guanting Li, Yourong Hu, Han Zhao, Ziyu Peng, Xin Shang, Jia Zhang, Kunxin Xie, Meiwei Li, Xiaohang Zhou, Qinyao Zhou, Kai Li, Fang Zhou, Heyao Wang, Zhijian Xu, Jiali Liu, Peng Sun

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Unveiling Tissue‐Specific RNA Landscapes in Mouse Organs During Fasting and Feeding Using Nanopore Direct RNA Sequencing by Chengfei Jiang, Ping Li, Haiming Cao

“…Abstract Understanding tissue‐specific RNA landscapes is essential for uncovering the functional mechanisms of key organs in mammals. …”
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A heuristic method for bi-decomposition of partial Boolean functions by Yu. V. Pottosin

“…The task is reduced to specification of those two functions. A method for bi-decomposition of incompletely specified (partial) Boolean function is suggested. …”
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New views on physiological functions and regulation of butyrylcholinesterase and potential therapeutic interventions by Samaneh Hajimohammadi, Samaneh Hajimohammadi, Oksana Lockridge, Patrick Masson

“…This review explores current insights into BChE functions and regulatory physiological mechanisms, with particular emphasis on its interaction with microRNAs (miRNAs) and defense against toxicants. …”
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