Assessment of Knowledge, Attitudes and Needs of Accredited Social Health Activist (ASHA) in Community based Cancer Awareness and Screening Programme: A Mixed Method Study from a Ru... by L Meenu, N Divyamol, K Anupriya, TK Abdu Saleem

“…For 10 (33.33%) participants, incomplete knowledge created anxiety. Their needs as facilitators emerged under two global themes: functional and aspirational. …”
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Unraveling the complex genetic landscape of OTOF-related hearing loss: a deep dive into cryptic variants and haplotype phasing by Pei-Hsuan Lin, Cheng-Yu Tsai, Yu-Ting Chiang, Chang-Han Ho, Yue-Sheng Lu, Jacob Shu-Jui Hsu, Yen-Fu Cheng, Shih-Feng Tsai, Chuan-Jen Hsu, Pei-Lung Chen, Chen-Chi Wu

“…Conclusions Our study highlights the genetic heterogeneity of DFNB9 and emphasizes the importance of population-specific variant interpretation. The integration of advanced sequencing technologies, predictive algorithms, and functional validation assays will improve the accuracy of molecular diagnosis and inform personalized treatment strategies for individuals with DFNB9. …”
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Neurovascular coupling of inhibitory control in late-onset depression: a simultaneous EEG-fMRI study by Elena Bondi, Alessandro Pigoni, Adele Ferro, Maria Pia Marra, Guido Nosari, Giandomenico Schiena, Fabio M. Triulzi, Anna M. Bianchi, Paolo Brambilla, Eleonora Maggioni

“…However, these were unimodal studies that provided an incomplete picture of the phenomenon, due to the single technique sensitivity and limited by the characteristics of each technique itself.In this study, we performed an EEG-driven fMRI analysis to explore the different hemodynamic correlates of specific event-related potentials (ERPs) of inhibitory control in late-onset MDD during a visuomotor Go/No-Go task. …”
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Reliability of the International Spinal Cord Injury Physical Therapy–Occupational Therapy Basic Data Set by Edelle C. Field-Fote, Kim D. Anderson, Maclain Capron, Ruediger Rupp, Linda Jones, Mary Schmidt-Read, Vanessa K. Noonan, Anne Bryden, Sara Mulroy, Walter Weiss, Mario Widmer, Henrik Hagen Poder, Vivien Jørgensen, Eimear Smith, Mariel Purcell, Fin Biering-Sørensen

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Maternal diet shapes infant microbiota and defensive capacity against infections in early life via differential human milk compositionResearch in context by Karla Rio-Aige, Marta Selma-Royo, Raúl Cabrera-Rubio, Sonia González, Cecilia Martínez-Costa, Margarida Castell, María J. Rodríguez-Lagunas, María Carmen Collado, Francisco J. Pérez-Cano

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Fibromyalgia Patients Have Markedly Greater Postoperative Opioid Use and Emergency Department Visits Following Bunionectomy by Andrew Sauer BA, Jung Yoo MD, Lara Atwater MD

“…This deformity typically has favorable surgical outcomes, but it can cause significant pain, functional limitations, and decreased quality of life if untreated. …”
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Arteriovenous cerebral high-flow shunts: genetic analysis of patients from a pediatric tertiary care center by Ferruccio Romano, Patrizia De Marco, Giulia Amico, Marisa Mallamaci, Marco Pavanello, Gianluca Piatelli, Marcello Scala, Federico Zara, Federico Zara, Federico Zara, Federico Zara, Federico Zara, Francesca Faravelli, Mariasavina Severino, Mariasavina Severino, Domenico Tortora, Domenico Tortora, Francesco Pasetti, Lucio Castellan, Silvia Buratti, Silvia Buratti, Silvia Buratti, Valeria Capra

“…The present study aimed to genetically characterize a cohort of 29 patients affected by arteriovenous cerebral high-flow shunts who were treated at a pediatric referral center.MethodsThe genetic techniques employed include next-generation sequencing, multiplex ligation-dependent probe amplification, and whole-exome sequencing.ResultsOf the 29 patients, 11 cases were found to have variants in genes associated with vascular functions, five cases received a genetic diagnosis, one case presented with a variant of uncertain significance in the EPHB4 gene, and five cases showed variants in novel genes possibly linked with cerebrovascular disorders.DiscussionWe provide extensive case descriptions and attempt to infer the genotype–phenotype correlations; variants in all of the known genes associated with arteriovenous cerebral shunts were reported in VGAM patients, while cutaneous angiomas were specific to RASA1 mutations. …”
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Single-cell multi-omics analysis identifies SPP1+ macrophages as key drivers of ferroptosis-mediated fibrosis in ligamentum flavum hypertrophy by Chengshuo Fei, Yanlin Chen, Ruiqian Tan, Xinxing Yang, Guanda Wu, Chenglong Li, Jiawei Shi, Shiyong Le, Wenjie Yang, Jiajia Xu, Liang Wang, Zhongmin Zhang

“…Subcluster analysis of fibroblasts revealed functional heterogeneity among distinct subpopulations, highlighting the functional characteristics and the metabolic dynamics of fibroblast with a high ferroptosis score (High Ferro-score FB). …”
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Completeness of repeated patient-reported outcome measures in adult rehabilitation: a randomized controlled trial in a diverse clinical population by Anne-Lene Sand-Svartrud, Ingvild Kjeken, Renate Foss Skardal, Gunhild M. Gjerset, Tonje Jossie Johnsen, Anne Dorte Lyken, Hanne Dagfinrud, Rikke Helene Moe

“…The longer data set expanded upon the brief set by including the Patient-Specific Functional Scale and the 29-item version of the PROMIS Profile instruments. …”
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Advances in Minimally Invasive Treatments for Prostate Cancer: A review of the Role of Ultrasound Therapy and Laser therapy by Corneliu-Dan Blendea, Mohammad Tazim Khan, Marius Stoian, Teodor Claudiu Ion Gligore, Ștefan Cuculici, Ion Lucian Stanciu, Mirela Gabriela-Irina Protosevici, Marius Iordache, Anca Buliman, Carmen Costea-Firan, Ioana Simona Cazacu, Liviu-Constantin Iordache, Doroteea Teoibaș-Șerban

“…HIFU consistently achieved precise tumor ablation with minimal collateral damage, leading to superior urinary and sexual function outcomes compared to traditional approaches. …”
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CLINICAL EFFICACY COMPARATIVE EVALUATION OF THE TREATMENT METHODS OF COMBINED DEFECTS AND DEFORMITIES OF THE ZIGOMA AND ORBIT by Yu.V. Chepurnyi, D.M. Chernohorskyi, O.I. Zhukovtseva, A.V. Kopchak

“…Zigoma and orbital defects still become an actual problem of maxilla-facial surgery due to limited possibilities to precise restoration of their complex anatomy. Functional unity of zigoma and orbit in aspects of eyeball support and protection increases requirements to reconstructive precision. …”
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Differentiation between bipolar disorder and major depressive disorder based on AMPA receptor distribution by Sakiko Tsugawa, Sakiko Tsugawa, Yuichi Kimura, Junichi Chikazoe, Hiroki Abe, Tetsu Arisawa, Mai Hatano, Waki Nakajima, Hiroyuki Uchida, Tomoyuki Miyazaki, Tomoyuki Miyazaki, Yuuki Takada, Akane Sano, Kotaro Nakano, Tsuyoshi Eiro, Akira Suda, Takeshi Asami, Akitoyo Hishimoto, Hideaki Tani, Nobuhiro Nagai, Teruki Koizumi, Shinichiro Nakajima, Shunya Kurokawa, Yohei Ohtani, Kie Takahashi, Yuhei Kikuchi, Taisuke Yatomi, Taisuke Yatomi, Ryo Mitoma, Shunsuke Tamura, Shunsuke Tamura, Shingo Baba, Osamu Togao, Yoji Hirano, Yoji Hirano, Yoji Hirano, Hirotaka Kosaka, Hidehiko Okazawa, Masaru Mimura, Takuya Takahashi, Takuya Takahashi

“…The model achieved an area under the curve of 0.80, sensitivity of 75.0%, and specificity of 77.8%. These findings suggest that AMPAR density measured with [11C]K-2 can effectively distinguish BD from MDD and may aid diagnosis, especially in patients with ambiguous symptoms or incomplete clinical presentation.…”
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Distinct subnetworks of the mouse anterior thalamic nuclei by Houri Hintiryan, Mitchell Rudd, Sumit Nanda, Adriana E. Gutierrez, Darrick Lo, Tyler Boesen, Luis Garcia, Jiandong Sun, Christian Estrada, Hyun-Seung Mun, Seita Yamashita, Yeji E. Han, Ian Bowman, Lin Gou, Chunru Cao, Jennifer Gonzalez, Keivan Moradi, Qiuying Zhao, Inga Yenokian, Aishwarya Dev, Brian Zingg, Hanpeng Xu, Qing Xue, Muye Zhu, Lijuan Liu, Xin Chen, Zhixi Yun, Hanchuan Peng, Nicholas N. Foster, Hong-Wei Dong

“…Structurally, the ATN facilitate communication among the neocortex, hippocampus, amygdala, and hypothalamus. Functionally, they play pivotal roles in learning, memory, spatial navigation, and goal-directed behaviors. …”
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Environmentally friendly synthesis of nanoporous silica materials using quercetin as a morphogenetic agent by A.R. Zare Hoseinabadi, E. Rafiei Taqanaki, S. Hafez Ghoran, A.M. Amani, H. Kamyab, A. Razmfarsa, E. Khalili, M. Yusuf, S. Rajendran

“…According to calculations based on the Brunauer–Emmett–Teller method, the specific surface area of Quercetin-templated mesoporous silica nanoparticles was determined to be 55.227 cubic meters. …”
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Deriving Test Suites with the Guaranteed Fault Coverage for Extended Finite State Machines by A. D. Ermakov, N. V. Yevtushenko

“…However, the fault coverage of tests covering appropriate paths, variables, etc. of the specification EFSM, remains rather obscure and such tests do not detect many functional faults in EFSM implementations. …”
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Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

“…Adolescent adaptive functioning was predicted not only by early childhood autistic symptoms and IQ and ADHD symptoms. …”
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Prokaryotic Argonautes – variations on the RNA interference theme by John van der Oost, Daan C. Swarts, Matthijs M. Jore

“…The key enzyme of the RNAi system is Argonaute (Ago), an endo-ribonuclease that uses a small RNA guide molecule to specifically target a complementary RNA transcript. Two functional classes of eukaryotic Ago have been described: catalytically active Ago that cleaves RNA targets complementary to its guide, and inactive Ago that uses its guide to bind target RNA to down-regulate translation efficiency. …”
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PRALU language - the tool for verifying digital devices by D. I. Cheremisinov

“…The task of creating a testbench for functional verification is considered. This verification process establishes the reconvergence (equivalence) of the device specification and the register-transfer level (RTL) model - a logical network which was built in the synthesis process. …”
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Diagnostic value of exercise stress echocardiography on a horizontal cycle ergometer in patients with low-risk non-ST elevation acute coronary syndrome by E. E. Abramenko, T. R. Ryabova, I. I. Yolgin, V. V. Ryabov

“…All patients had normal structural and functional cardiac parameters at rest. No adverse events were recorded during the tests. …”
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Neosemantization of Word NISHCHEBROD in Modern Russian Speech by N. G. Babenko, N. E. Likhina

“…The functional-semantic specificity of a word nishchebrod in its original and modern meaning and usage is considered. …”
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