Electrophysiological characterization of sourced human iPSC-derived motor neurons by Bohumila Jurkovicova-Tarabova, Robin N. Stringer, Zuzana Sevcikova Tomaskova, Norbert Weiss

“…These cells enable human-specific modeling of disease mechanisms and high-throughput drug screening. …”
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Modern Methodological Approaches to the Correction of Astenopia in Patients with Visual-Intensive Work by I. G. Ovechkin, E. I. Belikova, A. A. Kozhukhov, M. D. Pozharitskii, V. E. Yudin, A. A. Budko, A. V. Shakula

“…In addition, the practical expediency of applying a multidisciplinary approach to the correction of asthenopia, based on the complex effects of specific and non-specific methods of stimulation of vision. …”
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Therapy-induced senescence of glioblastoma cells is determined by the p21CIP1-CDK1/2 axis and does not require activation of DREAM by Christian Schwarzenbach, Justus Rinke, Juliana B. Vilar, Jason Sallbach, Larissa Tatsch, Ariane Schmidt, Anna Schöneis, Birgit Rasenberger, Bernd Kaina, Maja T. Tomicic, Markus Christmann

“…This process, which is inhibited by the CDK4-blocking drug palbociclib, is preceded by reactivation of the G1/S-specific E2F1-signaling pathway due to lack of functional DREAM activation. …”
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The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules by Dharshini Gopal, Juliette Wu, Julie Delaroche, Christophe Bosc, Manon De Andrade, Eric Denarier, Gregory Effantin, Annie Andrieux, Sylvie Gory-Fauré, Laurence Serre, Isabelle Arnal

“…Abstract Most eukaryotic cells have cilia that serve vital functions in sensing, signalling, motility. The core architecture of cilia is an array of microtubule doublets, which consist of a complete A-tubule and an incomplete B-tubule. …”
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Resolution of experimental malaria-associated acute respiratory distress syndrome is Alox12 independent and shows residual inflammation by Fran Prenen, Bram De Pauw, Sofie Knoops, Emilie Pollenus, Hendrik Possemiers, Johan Van Weyenbergh, Philippe E. Van den Steen

“…However, functional studies targeting the 12-lipoxygenase pathway with the ML355 inhibitor or with Maresin Conjugate in Tissue Regeneration 1 supplementation did not affect survival or resolution outcomes. …”
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Humanized mouse models in MDS by Raluca Munteanu, Diana Gulei, Cristian Silviu Moldovan, Emanuele Azzoni, Laura Belver, Richard Feder, Simina Pirv, Anca Dana Buzoianu, Hermann Einsele, Moshe Mittelman, Gabriel Ghiaur, Robert Hasserjian, Ciprian Tomuleasa

“…Improvements have been made to identify recurrent genetic mutations and their functional roles, but translating this into preclinical models is still difficult. …”
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Metabolic Analysis of the Mode of Action and Mode of Resistance for Novobiocin in Staphylococcus aureus by Weile Xie, Dan Luo, Zhe Wang

“…Further metabolomic analysis revealed the function of the major mutation (in gyrB) in relation to the potential mechanism through which S. aureus responds to novobiocin. …”
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Consumer-oriented review of digital diabetes prevention programs: insights from the CDC’s diabetes prevention recognition program by Benjamin Lalani, Jalene Shim, Vidhu Vadini, Yllka Valdez, Daniel Zade, Nestoras Mathioudakis

“…Data were extracted from three sources available to consumers: the CDC DPRP Registry, the CDC “Find a Lifestyle Program” Website, and program-specific websites. Extracted data included CDC recognition status, intended audience, available languages, program features (e.g., artificial intelligence, integration with smart devices), website availability and functionality, demonstrations of credibility (e.g., ADA endorsement), clinical performance metrics (e.g., average weight loss), and user experience factors (e.g., satisfaction). …”
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Comparative analysis of WC1.1+ and WC1.2+ γδ T cell subset responses from cattle naturally infected with Mycobacterium bovis to repeat stimulation with mycobacterial antigens. by Alia Parveen, Sajad A Bhat, Mahmoud Elnaggar, Kieran G Meade

“…The challenges in controlling and eradicating this zoonotic disease are compounded by our incomplete understanding of the host immune response. …”
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Generative Design of Housing Spatial Layout Based on Rectangular Spaces by Javid Ahmadi, Seyyed Mehdi Maddahi, Reza Mirzaei

“…The generative spatial layout design process can generate and optimize a wide range of design responses by complying with all desired requirements and criteria and evaluating them based on one or more specific functions. Considering the complexities and diversity of spatial layout responses, it is important to know the various mechanisms of the product design process related to them. …”
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PLGA Implants for Controlled Drug Delivery and Regenerative Medicine: Advances, Challenges, and Clinical Potential by Hossein Omidian, Renae L. Wilson

“…Recent innovations in polymer design, fabrication methods, and functional modifications have expanded their utility across diverse clinical domains, including oncology, neurology, orthopedics, and ophthalmology. …”
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Neural radiance fields assisted by image features for UAV scene reconstruction by Zhihong Chen, Xueyun Chen, Chenghong Ye, Shaojie Wu, Xiang Wu

“…To further improve synthesis quality, we also refine the loss function used during training to better guide network optimization. …”
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Emergent microenvironments of nucleoli by Matthew R. King, Kiersten M. Ruff, Rohit V. Pappu

“…In higher eukaryotes, the nucleolus harbors at least three sub-phases that facilitate multiple functionalities including ribosome biogenesis. The three prominent coexisting sub-phases are the fibrillar center (FC), the dense fibrillar component (DFC), and the granular component (GC). …”
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The superior colliculus directs goal-oriented forelimb movements by Shrivas Chaterji, Punarva H. Belliappa, Anupama Sathyamurthy

“…Anatomical studies identified the deep cerebellar nuclei and substantia nigra pars reticulata as sources of inputs to the SC, while functional studies revealed a role for nigrotectal, but not cerebellotectal, neurons in controlling reach endpoints. …”
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Development of a procedure for isolation, identification and quality assessment of bovine spermatids and evaluation of their fertilizing ability in vitro by Rolando Pasquariello, Francesca Di Filippo, Sai Kamal Nag Bonumallu, Fernanda Fagali Franchi, Ramona Pistucci, Federica Franciosi, Valentina Lodde, Alessandra Iannuzzi, Alberto Maria Luciano, Tiziana A. L. Brevini, Fulvio Gandolfi

“…Future applications of this approach, particularly if functional spermatids can be derived from spermatogonia or embryonic cells, could help shorten the generational interval in cattle breeding.…”
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Directions and Results of Punctuation Management by Albinas Drukteinis

“…For specific cases of interpretation of punctuation of syntactic units, the grammatical (syntactic) basis is important. …”
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Proposed framework regarding management of patients with breast cancer and anti-cancer treatment-related elevation in cardiac troponin by Michael Cronin, Dina Neiroukh, Aoife Lowery, William Wijns, Michael Kerin, Maccon Keane, Silvie Blazkova, Osama Soliman

“…Cardiac biomarkers are a vital component within the first edition of the European Society of Cardiology guidelines in Cardio-Oncology. Specifically, they are mentioned in the definition of mild asymptomatic cancer therapy-related cardiac dysfunction, where left ventricular systolic function is ≥50 % with two outcomes; either a new decrease in global longitudinal strain >15 % from baseline and/or a new rise in cardiac biomarkers above the defined 99th percentile cut off values. …”
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Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance. by Ashley Houlden, Kelly S Hayes, Allison J Bancroft, John J Worthington, Ping Wang, Richard K Grencis, Ian S Roberts

“…Thus infection of T. muris causes a significant and substantial impact on intestinal microbiota and digestive function of mice with affects in long term immune regulation.…”
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On the Special Case of the Definiteness Effect: Conditions for the Admission of the Quantifier “every” into the Post-Copular Nominal Group of the English Existential Construction... by O. V. Dolmatova

“…The reasons for the functioning of the quantifier “every” in the pivot noun phrases in English there-sentences are studied. …”
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Digital inequalities and U.S. undergraduate outcomes over the first two years of the COVID-19 pandemic. by Vikki S Katz, Amy B Jordan, Katherine Ognyanova

“…They were more likely to report having taken incomplete grades in specific courses and/or to have extended their time to graduation. …”
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