Analyzing Repetitive Narrative Patterns in Samad Behrangi’s Stories by Moharram Rezayati kishekhaleh, Mina Mehr Afarin

“…The current study investigated the effect and linguistic function of repetition in the context of Samad Behrangi's stories, which were primarily aimed at child and adolescent audiences. …”
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Maternal loss of mouse Nlrp2 alters the transcriptome and DNA methylome in GV oocytes and impairs zygotic genome activation in embryos by Zahra Anvar, Michael D. Jochum, Imen Chakchouk, Momal Sharif, Hannah Demond, Alvin K. To, Daniel C. Kraushaar, Ying-Wooi Wan, Michael C. Mari, Simon Andrews, Gavin Kelsey, Ignatia B. Van den Veyver

“…Maternal inactivation of genes encoding SCMC proteins has been linked to infertility and subfertility in mice and humans, but the underlying molecular mechanisms for the diverse functions of SCMC proteins, and specifically the role of NLRP2, are incompletely understood. …”
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Quantitative in vivo assessment of human mitral valve coaptation area after undersized ring annuloplasty repair for ischemic mitral regurgitationCentral MessagePerspective by Natalie T. Simonian, BS, Hao Liu, PhD, Alison M. Pouch, PhD, Joseph H. Gorman, III, MD, Robert C. Gorman, MD, Michael S. Sacks, PhD

“…This study underscores the importance of a rigorous understanding of the consequences of repair techniques on mitral valve behavior, as well as a patient-specific approach to ischemic mitral regurgitation treatment within the context of mitral valve and left ventricle function.…”
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Liquiritin improves macrophage degradation of engulfed tumour cells by promoting the formation of phagolysosomes via NOX2/gp91phox by Caiyi Yang, Kehan Chen, Yunliang Chen, Xuting Xie, Pengcheng Li, Meng Zhao, Junjie Liang, Xueqian Xie, Xiaoyun Chen, Yanping Cai, Bo Xu, Qing Wang, Lian Zhou, Xia Luo

“…The incomplete degradation of tumour cells by macrophages (Mϕ) is a contributing factor to tumour progression and metastasis, and the degradation function of Mϕ is mediated through phagosomes and lysosomes. …”
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Effective cellular and neutralizing immunity against SARS-CoV-2 after mRNA booster vaccination is associated with pDC and B cell activation by Dorit Fabricius, Carolin Ludwig, Carolin Ludwig, Matthias Proffen, Matthias Proffen, Janina Hägele, Janina Hägele, Judith Scholz, Judith Scholz, Christiane Vieweg, Christiane Vieweg, Immanuel Rode, Immanuel Rode, Simone Hoffmann, Simone Hoffmann, Sixten Körper, Sixten Körper, Hubert Schrezenmeier, Hubert Schrezenmeier, Bernd Jahrsdörfer, Bernd Jahrsdörfer

“…Cellular immunity was assessed by IFN-γ release assays, and flow cytometry was employed to analyze B cell and pDC frequencies, viability, and activation markers. Functional pDC-mediated T cell activation was evaluated in mixed lymphocyte cultures.ResultsmRNA booster vaccination stabilized high anti-SARS-CoV-2 IgG titers and neutralizing activity against wildtype virus across all regimens, with the homologous mRNA group showing the highest antibody titers and Omicron neutralization capacity. …”
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Defective autophagy is a key feature of cerebral cavernous malformations by Saverio Marchi, Mariangela Corricelli, Eliana Trapani, Luca Bravi, Alessandra Pittaro, Simona Delle Monache, Letizia Ferroni, Simone Patergnani, Sonia Missiroli, Luca Goitre, Lorenza Trabalzini, Alessandro Rimessi, Carlotta Giorgi, Barbara Zavan, Paola Cassoni, Elisabetta Dejana, Saverio Francesco Retta, Paolo Pinton

“…Cerebral cavernous malformation is a genetic disease that may arise sporadically or be inherited as an autosomal dominant condition with incomplete penetrance and variable expressivity. Causative loss‐of‐function mutations have been identified in three genes, KRIT1 (CCM1), CCM2 (MGC4607), and PDCD10 (CCM3), which occur in both sporadic and familial forms. …”
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PREDICATIVE ARRANGEMENT OF NATIONAL ANTHEM TEXTS IN ENGLISH- AND GERMAN- SPEAKING COMMUNITIES by Anatoliy M. Prykhodko, Nataliia V. Lazebna

“…This objective is supported by specific tasks, such as describing the current state of the problem in the humanities and clarifying the modal, temporal, and personal features of the studied texts. …”
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Epigenetic Insights into Tuberous Sclerosis Complex, Von Hippel–Lindau Syndrome, and Ataxia–Telangiectasia by Gavriel Hadjigavriel, Christina Stylianides, Evangelos Axarloglou, Maria Eleni Manthou, Efstratios Vakirlis, Paschalis Theotokis, Soultana Meditskou, Iasonas Dermitzakis

“…Increasingly, epigenetic regulatory mechanisms, such as DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA (ncRNA) activity, are recognized as key modulators of gene expression, cellular differentiation, and tissue-specific function. Disruption of these mechanisms has been implicated in disease pathogenesis, tumorigenesis, and neurodegeneration associated with TSC, VHL, and A-T. …”
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DTI-RME: a robust and multi-kernel ensemble approach for drug-target interaction prediction by Yuqing Qian, Xin Zhang, Yizheng Wang, Quan Zou, Chen Cao, Yijie Ding, Xiaoyi Guo

“…Abstract Background Drug-target interaction (DTI) refers to the specific mechanisms by which drug molecules interact with biological targets within a biological system. …”
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Biochemical characterization and activity profiling of recombinant phospholipase A2 from Hemiscorpius lepturus expressed in E. coli with in vivo antibody response by Moslem Najafi, Delavar Shahbazzadeh, Parichehreh Yaghmaie, Hasan Mirzahoseini

“…New Zealand Albino male rabbits were immunized with 100 µg/ml at 10–12-day intervals using Complete and Incomplete Freund’s Adjuvant. Specific rabbit anti-PLA2 polyclonal antibodies were detected using ELISA. …”
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Characteristics of symptomatic epilepsy and other neurological disorders in children with lissencephaly by V. I. Guzeva, I. V. Ochrim, V. R. Kasumov, O. V. Guzeva, V. V. Guzeva, N. E. Maksimova

“…The probable cause of the deterioration is considered to be the “Transportation” function-specific astrocytes and radial glial fibers involved in the migration of germ cells. …”
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THE ROLE OF MICROTRAUMA IN THE DEVELOPMENT OF BACTERIAL CORNEAL ULCERS by A. I. Hazamova, E. N. Verigo, E. V. Chentsova

“…Conservative therapy  included specific, pathogenetic, symptomatic and antiallergic medications. …”
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Biventricular electromechanical dysfunction and molecular remodeling in a rat model of advanced pulmonary arterial hypertension by Francesco Paolo Lo Muzio, Alessia Caputo, Rosario Statello, Mirko Hu, Roberta Maestri, Giovanna Pelà, Aderville Cabassi, Margherita Burattini, Giacomo Rozzi, Silvia Berrettoni, Barbara Montanini, Stefano Rossi, Lorenzo Fassina, Giovanni Battista Luciani, Gianluigi Condorelli, Michele Miragoli

“…Methods In this study, we investigate the late-stage effects of PAH on both electrical and mechanical functions, as well as their coupling, in each ventricle using the monocrotaline-treated rat model. …”
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Bioinformatic analysis, clinical implications and experimental validation of ferroptosis-related feature gene in IgA nephropathy: focus on DUSP1 by Tingting Liu, Tingting Pan, Mingxin Chang, Shaojie Fu, Hongzhao Xu, Hao Wu, Zhonggao Xu, Yanli Cheng

“…Despite growing interest in this field, the exact molecular pathways governing ferroptosis activation in IgAN progression remain incompletely understood and require systematic investigation. …”
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Prognostic significance and immune infiltration analysis of HMGA2 in endometrial cancer by Peng Jiang, Jiaxin Yu, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Chunxia Gong, Hangkun Yu, Yi Luo, Zhuoying Hu

“…Functional enrichment analysis (GSEA and KEGG) identified HMGA2-associated pathways. …”
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SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts by Tongzhu Jin, Huiying Gao, Yuquan Wang, Zhiwei Ning, Danyang Bing, Yan Wang, Yi Chen, Xiaomu Tian, Qiudi Liu, Zhihui Niu, Jiayu Guo, Jian Sun, Ruoxuan Yang, Qianqian Wang, Shifen Li, Tianyu Li, Yuhong Zhou, Wenxin He, Yanjie Lu, Yunyan Gu, Haihai Liang

“…Although the role of alternative splicing (AS) in the pathogenesis of organ fibrosis has garnered increasing attention, its specific contribution to pulmonary fibrosis remains incompletely understood. …”
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Low-frequency rTMS modulates small-world network properties in an AVH-related brain network in schizophrenia by Lin Zhang, Li Guo, Xiaohui Liu, Jing Han, Yuanqiang Zhu, Chaozong Ma, Ye Li, Weiliang Ye

“…Resting-state fMRI data were collected before and after treatment to assess functional connectivity within the predefined 35-region AVH-related network. small-worldness (σ), normalized clustering coefficient (γ), and normalized characteristic path length (λ), as well as functional segregation (clustering coefficient [Cp], local efficiency [El]) and functional integration (global efficiency [Eg], characteristic path length [Lp])—were analyzed before and after rTMS. …”
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A one year longitudinal study of cortical myelination changes following pediatric mild traumatic brain injury by Jessica R. McQuaid, Tracey V. Wick, Josef Ling, Andrew B. Dodd, Divyasree Sasi Kumar, Upasana Nathaniel, Samuel D. Miller, Vadim Zotev, Harm J. van der Horn, John P. Phillips, Richard A. Campbell, Robert E. Sapien, Timothy B. Meier, Andrew R. Mayer

“…Clinical results suggested only partial recovery from post-concussive symptoms from V1 to V3, with similar incomplete recovery of sleep, functional outcomes, behavior, and long-term memory. …”
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Ultrasonographic evaluation of diastasis recti abdominis and its association with pelvic floor dysfunction in postpartum women: a cross-sectional study of a two-year retrospective... by Manrong Li, Nana Wang, Rui Wang, Bingyin Liang

“…Ultrasound was employed to evaluate the DRA features, specifically the condition of the abdominal midline and echo types. …”
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Sphingolipid Metabolism and Signalling Pathways in Heart Failure: From Molecular Mechanism to Therapeutic Potential by Zhao M, Bian R, Xu X, Zhang J, Zhang L, Zheng Y

“…Given the complexity of sphingolipid metabolism and its involvement in diverse regulatory biological processes, a comprehensive understanding of its roles at both the cellular and organismal levels in physiopathology remains incomplete. Therefore, this review aims to explore the physiological functions, regulatory mechanisms, and therapeutic potential of sphingolipid metabolism. …”
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