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5421
Cyber threats in mobile healthcare applications: systematic review of enabling technologies, threat models, detection approaches, and future directions
Published 2025-07-01“…The findings showed that much work is left undone which we offered in open research prospects. …”
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5422
Understanding the Intersection Between Hormonal Dynamics and Brain Plasticity in Alzheimer's Disease: A Narrative Review for Implementing New Therapeutic Strategies
Published 2025-07-01“…Various factors are implicated in the pathogenesis to neuroplasticity alteration in the brain of an individual afflicted with AD. …”
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5423
Comparing rates and characteristics of emergency department presentations related to pharmaceutical opioid poisoning in Australia: a study protocol for a retrospective observationa...
Published 2020-09-01“…Introduction and aims Pharmaceutical opioids are an important contributor to the global ‘opioid crisis’, and are implicated in 70% of Australia’s opioid-related mortality. …”
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5424
CEBPB dampens the cuproptosis sensitivity of colorectal cancer cells by facilitating the PI3K/AKT/mTOR signaling pathway
Published 2024-11-01“…CEBPB was strongly implicated in copper ion homeostasis and the mTOR signaling pathway in CRC. …”
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5425
Characterizing the regulatory effects of H2A.Z and SWR1-C on gene expression during hydroxyurea exposure in Saccharomyces cerevisiae.
Published 2025-01-01“…While H2A.Z has often been implicated in transcription regulation, htz1Δ mutants exhibit minimal changes in gene expression compared to wild-type. …”
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5426
Prevalence of adverse drug reactions in the primary care setting: A systematic review and meta-analysis.
Published 2021-01-01“…While a substantial body of work has been undertaken to characterise ADRs in the hospital setting, the overall burden of ADRs in the primary care remains unclear.…”
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5427
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
Published 2011-10-01“…The effectiveness of HSP90 and VEGFR signaling inhibitors in suppressing OM in the Junbo model implicates HIF-mediated VEGF as playing a pivotal role in OM pathogenesis. …”
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5428
RNA guanine content and G-quadruplex structure tune the phase behavior and material properties of biomolecular condensates
Published 2025-03-01“…In this study we focused on the model protein, Fragile X mental retardation protein (FMRP), to investigate how G4-containing RNA sequences impact the phase behavior and material properties of condensates. FMRP is implicated in the development of Fragile X Syndrome, and is enriched in neuronal granules where it is thought to aid in mRNA trafficking and translational control. …”
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5429
Preconcentration and determination of Metformine Hydrochloride in different samples by cloud point extraction coupling with uv-visible spectrophotometry
Published 2016-06-01“…This work was influenced the separation and preconcentration steps were carried out to determination of metformin (MET) in pharmaceutical preparations and human serum samples. …”
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5430
A Scoping Review of Eosinophilic Pneumonia and Antidepressants: An Association Not to Be Overlooked
Published 2025-01-01“…Clinical suspicion must be aroused, as early recognition would prevent unnecessary work-up and navigation of the diagnosis.…”
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5431
Intellectual Capital and Its Impact on the Financial Performance of Russian Manufacturing Companies
Published 2017-03-01“…The questions of how IC and its elements work on emerging markets remains under-researched due to a lack of empirical research devoted to this topic. …”
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5432
Immunisation with recombinant PfEMP1 domains elicits functional rosette-inhibiting and phagocytosis-inducing antibodies to Plasmodium falciparum.
Published 2011-01-01“…<h4>Background</h4>Rosetting is a Plasmodium falciparum virulence factor implicated in the pathogenesis of life-threatening malaria. …”
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5433
Multifaceted investigations of PSMB8 provides insights into prognostic prediction and immunological target in thyroid carcinoma.
Published 2025-01-01“…A constructed predicted competing endogenous RNA (ceRNA) network implicated PSMB8 in complex post-transcriptional regulation. …”
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5434
Enhanced glutamatergic and decreased GABAergic synaptic appositions to GnRH neurons on proestrus in the rat: modulatory effect of aging.
Published 2010-04-01“…<h4>Background</h4>Previous work by our lab and others has implicated glutamate as a major excitatory signal to gonadotropin hormone releasing hormone (GnRH) neurons, with gamma amino butyric acid (GABA) serving as a potential major inhibitory signal. …”
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5435
Perspectives on adherence to prescribed home exercises after polytrauma: A qualitative study
Published 2025-06-01“…Pain significantly hindered adherence, while family support was a key enabler. Clinical implication: Physiotherapists should work collaboratively with patients to develop inclusive HEPs that consider their demographic, social, psychological, physical and environmental context.…”
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5436
Varicella Viruses Inhibit Interferon-Stimulated JAK-STAT Signaling through Multiple Mechanisms.
Published 2015-05-01“…SVV-infected rhesus fibroblasts were refractory to IFN stimulation displaying reduced protein levels of IRF9 and lacking STAT2 phosphorylation. Since previous work implicated involvement of the VZV immediate early gene product ORF63 in preventing ISG-induction we studied the role of SVV ORF63 in generating resistance to IFN treatment. …”
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5437
Evaluation of Workers and Customers Exposure to Noise Level in Delta Mall and Robinson Plaza, Delta State, Nigeria
Published 2018-08-01“…This research work titled “Evaluation of Noise Exposure Level in Delta Mall and Robinson Plaza” was aimed at the determination of the noise exposure level and it’s implication to the health of workers/individuals in Delta Mall and Robinson Plaza. …”
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5438
Determination of molecular mechanisms of development and course of experimental diabetes mellitus in Wistar rats
Published 2023-07-01“…Understanding these mechanisms is crucial for the development of effective methods for treating and preventing diabetes. The aim of the work is analysis of the expression of genes, related to diabetes in pancreatic tissue samples of Wistar rats. …”
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5439
Adenosine A1 receptor activation increases myocardial protein S-nitrosothiols and elicits protection from ischemia-reperfusion injury in male and female hearts.
Published 2017-01-01“…Nitric oxide (NO) plays an important role in cardioprotection, and recent work from our group and others has implicated protein S-nitrosylation (SNO) as a critical component of NO-mediated protection in different models, including ischemic pre- and post-conditioning and sex-dependent cardioprotection. …”
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5440
Cytochrome P450 CYP76F14 Mediates the Conversion of Its Substrate Linalool in Table Grape Berries
Published 2025-06-01“…While the cytochrome P450 enzyme CYP76F14 is implicated in aroma biosynthesis, its functional role in grape berries remains uncharacterized. …”
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