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4421
Causal Relationships Between Abdominal Obesity, Type 2 Diabetes, Fasting Insulin, and Cervical Disc Disorders, Osteoporosis, and Rheumatoid Arthritis: A Mendelian Randomization Stu...
Published 2025-08-01“…These findings provide novel insights into the interplay between metabolic factors and prevalent orthopedic conditions, offering valuable implications for clinical decision-making and targeted disease management strategies. …”
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4422
The evolution and morphodynamic characteristics of shoals and troughs in Lingdingyang Bay of the Pearl River Estuary
Published 2025-01-01“…However, their definition and morphodynamic characteristics, influenced by the complex dynamic environment, remain a critical challenge. This work introduces a depth–area spatial function as a quantitative criterion for the definition of shoals and troughs, while simultaneously elucidating their geodynamic implications. …”
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4423
A secondary metabolite of Limosilactobacillus reuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis
Published 2025-03-01“…Differences in pathology occurred in parallel with a pks-dependent downregulation of AhR-related genes, reduced occludin expression in the forebrain, and altered concentrations of immune cells. This work establishes a molecular foundation for strain-specific effects on autoimmunity, which has implications for our understanding of how microbes contribute to chronic conditions and the selection of microbial therapeutics.…”
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4424
Migrations from Yugoslavia to Germany: Migrants, emigrants, refugees and asylum-seekers
Published 2005-01-01“…From 1954 to 1967 migration of Yugoslav citizens had not yet been intensive and their intention was mostly to work abroad. Illegal employment was, however, prominent at that time. …”
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4425
As contribuições dos estudos de Vygotski à educação: notas sobre um pensamento revolucionário
Published 2018-08-01“…Thus, when describing its trajectory and the pillars that support its theorization, it is tried to evidence the impact of its work to the school quotidian and the centrality of the education in the constitution of superior psychological functions, which allow to the human genus the auto dominion of its will and actions. …”
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4426
Medication non-adherence: reflecting on two decades since WHO adherence report and setting goals for the next twenty years
Published 2024-12-01“…BackgroundNon-adherence to medication remains a persistent and significant challenge, with profound implications for patient outcomes and the long-term sustainability of healthcare systems. …”
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4427
Investigating the Impact of Circulating Immune Cells on Acne Using Mendelian Randomization
Published 2025-07-01“…Xudong Wang,1,2,* Shaoyu Guan,3,* Zhikuan Xia,2 Xin Zhang,2 Yu Bai,2 Qiang Li,4 Haitao Li,2 Rongya Yang2 1Southern Medical District of Chinese PLA General Hospital, Beijing, 100843, People’s Republic of China; 2Department of Dermatology, Seventh Medical Center of Chinese PLA General Hospital, Beijing, 100010, People’s Republic of China; 3Pharmaceutical Sciences Research Division, Department of Pharmacy, Medical Supplies Centre of PLA General Hospital, Beijing, 100853, China; Medical School of Chinese PLA, Beijing, 100853, People’s Republic of China; 4Medical Health Care Department, Air Force Medical Center PLA, Beijing, 100142, People’s Republic of China*These authors contributed equally to this workCorrespondence: Rongya Yang, Department of Dermatology, Seventh Medical Center of Chinese PLA General Hospital, Beijing, 100010, People’s Republic of China, Email yangrya@sina.com Haitao Li, Department of Dermatology, Seventh Medical Center of Chinese PLA General Hospital, Beijing, 100010, People’s Republic of China, Email 343266881@qq.comBackground: While growing evidence suggests the intricate relationship between immune cells and the pathogenesis of acne, the causative implications underlying these associations remain poorly characterized. …”
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4428
Association of Pulmonary Hypertension With Outcomes in Kidney Transplant Recipients
Published 2025-07-01“…Therefore, this study sought to directly evaluate the prognostic implications of pretransplant PHTN in one of the largest kidney transplant cohorts to date. …”
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4429
Medical education under siege: the war’s impact on medical and paramedical Sudanese students
Published 2025-07-01“…In Sudan, the war that erupted on the 15th of April 2023 has imposed significant implications and challenges for medical education in Sudan. …”
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4430
Characterization of the virulence shaping and adaptability in the methicillin-resistant Staphylococcus aureus ST9 lineage
Published 2025-07-01“…These findings emphasize the need for continued surveillance and targeted strategies to control the spread of ST9 MRSA, with important implications for diagnostic and therapeutic approaches.…”
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4431
Identidad profesional diada docente-discente: Implicancias en el proceso de enseñanza-aprendizaje de matronería
Published 2025-07-01“…Abstract: Introduction: Professional identity in midwifery begins in initial training with the support of the teaching staff, who must not only acquire pedagogical tools, but also consolidate their own version of themselves. This work aims to recognize the professional identity of the teacher-student dyad and its implications in the teaching-learning process through the analysis of narratives for continuous improvement in the training of this discipline. …”
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4432
Bacterial type IV secretion system induces specific and nonspecific protective immunity
Published 2025-08-01“…By uncovering new ways bacteria influence immune memory, this work advances our understanding of host defense mechanisms and opens new avenues for designing strategies to enhance protection against infectious diseases.…”
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4433
ECONOMIC AND LEGAL POLICY IN THE FIELD OF SECURITY ON THE MARKET OF NON-BANKING FINANCIAL SERVICES IN UKRAINE
Published 2025-07-01“…Their characteristic feature is a clear definition of the scope of action (limits of legal regulation), which covers the subject area of work of public administration bodies and managerial social relations that arise in the process of their performance of power and organizational functions. …”
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4434
Cuproptosis: a novel therapeutic mechanism in lung cancer
Published 2025-06-01“…However, the mechanisms underlying cuproptosis in lung cancer remain to be fully elucidated. Purpose In this work, we primarily examine the most recent research on copper homeostasis, cuproptosis mechanisms, and the connection between lung cancer and cuproptosis. …”
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4435
Contactless Detection of Abnormal Breathing Using Orthogonal Frequency Division Multiplexing Signals and Deep Learning in Multi-Person Scenarios
Published 2025-01-01“…Future work will expand the dataset and refine the models to improve performance across diverse respiratory patterns and real-world data from a respiratory unit.…”
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4436
Team members’ direct participation in decision-making processes and the quality of decisions
Published 2023-01-01“…The participants played the role of members of a newly established project team that must plan its own work. The task concerned a problem that requires the analysis of a number of dependencies between sub-problems, in contrast to eureka-type problems. …”
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4437
Exploring meso- and macro-level contextual factors associated with inequalities in program adoption during statewide scale-up of TransformUs Primary, a whole-school physical activi...
Published 2025-08-01“…Findings inform the need to work with stakeholders in scale-up to prioritize dissemination strategies that have a discernible impact on adoption above others and consider targeted efforts to reach regional/rural and non-government schools.…”
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4438
Climate change, poverty, and health: A scoping review of the Canadian context
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4439
Sensitive and Highly Selective Detection of Organophosphorus Pesticides Using Organic Field‐Effect Transistors
Published 2025-04-01“…Additionally, a portable monitoring applet is developed, enabling real‐time assessment of the pesticide contamination status of samples based on the current response. This work provides a new avenue for constructing highly sensitive, real‐time, high‐flux intelligent agriculture sensing technology.…”
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4440
An Increased Frequency in HLA Class I Alleles and Haplotypes Suggests Genetic Susceptibility to Influenza A (H1N1) 2009 Pandemic: A Case-Control Study
Published 2018-01-01“…Selective classical HLA class I allele and haplotype combinations predispose individuals towards susceptibility or protection against the influenza A H1N1/09 pandemic. This work has significant implications for accessing population transmission risk for A H1N1/09 or a similar strain breakout in the future.…”
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