Digital Methods to Study (and Reduce) the Impact of Disinformation by Miriam Di Lisio, Domenico Trezza

“…This problem has visible implications on global security, both political (e.g.the QANON case) and health (anti-Covid vaccination and No-Vax fake news). …”
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Foreign Language Teaching Anxiety among Non-native Teachers of English: A Sample from Turkey by Gökhan Öztürk

“…The participants included 103 instructors working at six different state universities and the data were collected through both qualitative and quantitative methods. …”
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Impact of Polystyrene Microplastics on Human Sperm Functionality: An In Vitro Study of Cytotoxicity, Genotoxicity and Fertility-Related Genes Expression by Filomena Mottola, Maria Carannante, Ilaria Palmieri, Lorenzo Ibello, Luigi Montano, Mariaceleste Pezzullo, Nicola Mosca, Nicoletta Potenza, Lucia Rocco

“…Possible environmental and working exposure to pollutants should be considered during the counselling for male infertility.…”
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Actionable Variants of Unknown Significance in Inherited Arrhythmogenic Syndromes: A Further Step Forward in Genetic Diagnosis by Estefanía Martínez-Barrios, Andrea Greco, José Cruzalegui, Sergi Cesar, Nuria Díez-Escuté, Patricia Cerralbo, Fredy Chipa, Irene Zschaeck, Miguel Fogaça-da-Mata, Carles Díez-López, Elena Arbelo, Simone Grassi, Antonio Oliva, Rocío Toro, Georgia Sarquella-Brugada, Oscar Campuzano

“…<b>Methods:</b> In this work, we present a new algorithm for the genetic interpretation of the remaining rare variants in order to shed light on their potential clinical implications and reduce the burden of unknown significance. …”
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Extracorporeal carbon dioxide removal compared to ventilation alone in patients with acute hypoxaemic respiratory failure: cost-utility analysis of the REST RCT by Ashley Agus, James J. McNamee, Colette Jackson, Danny F. McAuley

“…Background Acute hypoxaemic respiratory failure requiring mechanical ventilation is a major cause of morbidity and mortality and has significant resource implications in terms of intensive care unit and hospital stay. …”
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Exploring perceptions and awareness of artificial light: A qualitative study among medical and non-medical college students in an urban area of Southern India by Mithra Prasanna, Thapar Rekha, Mallya Ajay, Prabhakar Madhu Malar, Pandey Sonali, Agrawal Yash, Vats Anmol, Agarwal Shreya, Maurya Sarthak, Patel Sneha, Mohanty Marmit, Hooda Divya

“…Conclusion: The findings emphasise the need for greater awareness of the implications of artificial light use, promoting healthier practices and informed decisions among students. …”
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“Clinical Stability” and Propensity Score Matching in Cardiac Surgery: is the clinical evaluation of treatment efficacy algorithmdependent in small sample size settings? by Daniele Bottigliengo, Aslıhan Sentürk Acar, Veronica Sciannameo, Giulia Lorenzoni, Jonida Bejko, Tomaso Bottio, Emanuele Cozzi, Marta Vadori, Jean-Paul Soulillou, Jean Christian Roussel, Thierry Le Torneau, Thomas Senage, Rafael Mañez, Cristina Costa, Vered Padler-Karavani, Sofia Scali, Massimiliano Carrozzini, Emilia Fiorello, Samuel Fusca, Gino Gerosa, Ileana Baldi, Paola Berchialla, Dario Gregori

“…Conclusion: Clinical stability of matched samples created with different statistical methods should always be evaluated to ensure reliability of final estimates. This work opens the door for future investigations that fully assess the implications of this finding.…”
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Unraveling the assembly mechanisms and differentiated ecological functions of protist cell-associated and free-living bacterial communities during two Prorocentrum shikokuense bloo... by Xiaoyu Wang, Xin Lin, Huatao Yuan, Hao Luo, Sitong Lin, Wenxue Wu, Ling Li

“…Furthermore, cell-associated communities showed enriched ecological functions in nutrient cycling and cytolysis. The ecological implications of the higher abundance of Rhizobiales in cell-associated communities for nitrogen fixation were also discussed. …”
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Myeloid TGF-β signaling shapes liver macrophage heterogeneity and metabolic liver disease pathogenesis by Ziyi Meng, Xiaoxue Qiu, Zhimin Chen, Yu-tung Lee, Linkang Zhou, You Lu, Tongyu Liu, Siming Li, Benjamin Levi, Katherine A. Gallagher, Jiandie D. Lin

“…By elucidating how TGF-β signaling regulates macrophage function, our work paves the way for targeted interventions that modulate immune responses to improve liver health. …”
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Systemic Drowning Prevention - A Theoretical Framework for the Development of Evidence-Based Interventions by Martin Hafen, Reto Abächerli, Tina van Duijn

“…Process: This paper describes a systemic drowning prevention framework based on the main tenets of Luhmann’s systemic theory (Luhmann, 1995; Hafen, 2020). Previous work by Hafen (2020) is advanced by integrating systems theory, evidence-based practice, and insight from recent drowning prevention research.  …”
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IVIG Resistance in Kawasaki Disease: Clinical and Laboratory Risk Factors and the Potential Role of Administration Timing by Peng Y, Jing F, Liu D, Li B, Xu Y, Tan Z, Chen O, Yang Y, Si F, Jiang W, Li C, Cheng Z, Zhou X, Feng S, Su Y, Yi Q

“…However, the clinical implications of delaying treatment are uncertain, and early IVIG administration remains essential to prevent cardiovascular complications. …”
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The Health Effects of Gender-Based Violence in Conflict by Shadab Shahali

“…Gender-based violence (GBV) in conflict zones is a widespread and devastating issue with significant implications for the health and well-being of affected populations. …”
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Polar Ocean Mixing by Internal Tsunamis (POLOMINTS) by Michael Meredith, Katharine Hendry, E. Povl Abrahamsen, J. Alexander Brearley, Emma Young, David Munday, Hugh Venables, Anna Hogg, Benjamin Wallis, Katrien Van Landeghem, Filipa Carvalho, Andrew Yool, Amber Annett, Alberto Naveira Garabato, Mark Inall, Katy Sheen, Andrew Fleming, Estelle Dumont, Oskar Głowacki, Carlos Moffat, Neil Fraser, Sarah Gille, Matthew Alford, Rebecca Jackson, Katherine Retallick

“…The fieldwork will be especially photo- and video-genic and will lead to outstanding outreach and impact opportunities, and we will work with media agencies seeking to tell compelling stories about the extremes of the Earth.…”
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Antivenomics and in vivo preclinical efficacy of six Latin American antivenoms towards south-western Colombian Bothrops asper lineage venoms. by Diana Mora-Obando, Davinia Pla, Bruno Lomonte, Jimmy Alexander Guerrero-Vargas, Santiago Ayerbe, Juan J Calvete

“…Defining the phylogeographic boundaries of an antivenom's effectivity has implications for optimizing its clinical use. However, the molecular bases and impact of venom compositions on the immune recognition and neutralization of the toxic activities of across geographically disparate populations of B. asper lineages has not been comprehensively studied.…”
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Identification and evolution of novel cfr-carrying plasmids in XDR Klebsiella pneumoniae strains from a chicken farm by Yiming Feng, Tiantian Li, Shiyun Zhao, Mengxiang Zheng, Jiaxing Shen, Xiaoying Wu, Xuexue Li, Yajun Zhai, Li Yuan, Jianhua Liu, Gongzheng Hu, Yushan Pan, Dandan He

“…Importantly, the transferability of the cfr-positive plasmid to E. coli demonstrates the potential for cross-species dissemination. This work sheds light on how agricultural practices contribute to the persistence and evolution of resistance genes, with significant implications for public health and the global fight against antimicrobial resistance.…”
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A cryptic elapid snake persists in the wake of catastrophic wildfires by Mitchell J. Hodgson, Alexandra K. Ross, Yingyod Lapwong, Santiago Cuartas, Bridget Roberts, Owen Price, Jonathan Webb, Nicola Sentinella, Joshua Lee, Shawn W. Laffan, Hugh M. Burley, Finlay McIntosh, Mike Letnic

“…The increased severity and frequency of bushfires accompanying human-induced global warming have dire implications for biodiversity conservation. Here we investigate the response of a cryptic, cool-climate elapid, the mustard-bellied snake Drysdalia rhodogaster, to the extensive Black Summer fires of 2019/2020 in south-eastern Australia. …”
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Reasons for doctor migration from South Africa by Marlene M. Bezuidenhout, Gina Joubert, Louis A. Hiemstra, Magdalena C. Struwig

“…Participants had to be graduates from South African medical schools/faculties, living abroad and in possession of a permanent work permit in the countries where they were employed. …”
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Legionella pneumophila type II secretome reveals a polysaccharide deacetylase that impacts intracellular infection, biofilm formation, and resistance to polymyxin- and serum-mediat... by Carlton O. Adams, Jackson A. Campbell, Beichang Zhang, Leanne Cleaver, Sarah B. Bier, Joshua Mayoral, Richard C. White, James A. Garnett, Nicholas P. Cianciotto

“…Moreover, since T2SSs and homologs of PdaA were found in many other bacteria, our findings should also have implications for understanding other infectious diseases and environmental processes.…”
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Understanding the Phenomenon of Smuggling from the Perspective of Activists Known as “Shoti” by Ali Feizolahi, Zahra Rezaeinasab, Shabnam Yari

“…The target population consisted of Shoti activists residing in the city of Pol-e-Dokhtar, Lorestan Province, who possessed at least 3 years of experience in commodity smuggling and were actively engaged in this work at the time of the study. The research sample comprised 14 individuals selected through the snowball sampling method based on the criterion of theoretical saturation. …”
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Single-cell analysis of mature hepatocytes reveals an IRF1-driven restriction of HDV infection by Frauke Lange, Jonathan Garn, Matthias Bruhn, Thomas Pietschmann, Arnaud Carpentier

“…We identified IRF1 as a constitutive cellular factor restricting HDV infection in mature hepatocytes, particularly targeting HDV in the cytoplasm. This work improves our understanding of mature cell culture models for HDV, needed to decipher its host–pathogens interactions. …”
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