Heart failure with reduced ejection fraction polypill implementation strategy in Sri Lanka: design and protocol of a pilot type I hybrid randomised clinical trial by Anushka Patel, Anthony Rodgers, Dorairaj Prabhakaran, Anubha Agarwal, Mark D Huffman, Abdul Salam, Rupasvi Dhurjati, Asita de Silva, Charles W Goss, Mansi Agarwal, Saumiyah Ajanthan, Anuradha Dahanayaka, Chanaka Fernando, Gamini Galappatthy, Adam Hively, Pathiyil B Jayagopal, Padinhare P Mohanan, Mohamed Rahuman, Karl Roberts, Hyndavi Salwa

“…The findings of this pilot trial will inform the design and implementation of a future large-scale type I hybrid trial to assess the efficacy and safety of an HFrEF polypill in improving clinical outcomes.Trial registration numbers Sri Lanka Clinical Trials Registry (SLCTR/2024/003); ClinicalTrials Registry (NCT06831864).…”
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Multicomponent intervention for controlling hypertension in the adult rural population of Pakistan: a protocol for a hybrid type III implementation-effectiveness cluster randomised controlled trial by Catherine Hewitt, Aziz Sheikh, Simon Walker, Sajid Soofi, Kamran Siddiqi, Zulfiqar Ahmed Bhutta, Zainab Samad, Aysha Almas, Saima Afaq, Hajra Khwaja, Shiraz Hashmi, Imran Naeem, Salim S Virani, Saira Bukhari, Sawera Hanif

“…In this study, we will develop and test strategies for the implementation and scale-up of a proven multicomponent hypertension intervention (MCHI) in Pakistan that comprises health education, blood pressure (BP) monitoring and referrals by lady health workers (LHWs) and hypertension management by physicians in primary care settings.Methods and analysis In this 24-month hybrid type III implementation-effectiveness cluster-randomised controlled trial, we will recruit 3000 adult hypertensive patients from two rural districts of Pakistan. …”
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A Multicomponent Strategy to Improve HIV Pre-Exposure Prophylaxis in a Southern US Jail: Protocol for a Type 3 Hybrid Implementation-Effectiveness Trial by Ank E Nijhawan, Jana Kholy, Julia L Marcus, Timothy P Hogan, Robin T Higashi, Jacqueline Naeem, Laura Hansen, Brynn Torres, Barry-Lewis Harris, Song Zhang, Douglas Krakower

“…MethodsThis is a type 3 hybrid implementation-effectiveness study that takes a combined approach by assessing the implementation of a strategy to identify candidates for PrEP at the DCJ and linking them to PrEP providers upon community re-entry while also gathering information about clinical outcomes. …”
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A hybrid type I randomized effectiveness-implementation trial of a Naturalistic Developmental Behavioral Intervention in the Part C early intervention system: study protocol by Allison L. Wainer, Sarah R. Edmunds, Alice S. Carter, Wendy L. Stone, R. Christopher Sheldrick, Sarabeth Broder-Fingert, Yael S. Stern, Ellie Harrington, Lisa V. Ibanez, Brooke Ingersoll

“…Methods This hybrid type 1 effectiveness/implementation trial uses a multi-site randomized control design to simultaneously test effectiveness and collect implementation data on CI-RIT in the Part C EI system across four states: Illinois, Massachusetts, Michigan and Washington. …”
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Impact of an adapted diabetes prevention program in a spanish primary care setting: protocol for a type II hybrid effectiveness-implementation cluster-randomized trial (ALADIM) by Miquel Bennasar-Veny, Manuela Abbate, Miquel Colom-Rosselló, Laura Capitán-Moyano, Ivonne C. Hernández-Bermúdez, Ignacio Ricci-Cabello, Aina M. Yañez, Maria E. Fernandez, the ALADIM investigators

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Comparative study of three types of technology fee system for R&D performance under government R&D projects by JaeHoon Lee

“…This study analyzes the concepts of three types of technology fees, namely general technology fees, so-called “government-paid technology fees”, and “self-implemented technology fees”, along with their regulatory history. …”
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Implementation and Evaluation of a Best Practice Advisory to Reduce Inequities in Technology Use for People With Type 1 Diabetes: Protocol for a Mixed Methods, Nonrandomized Controlled Trial by Nestoras Mathioudakis, Risa Wolf, Abha Choudhary, Georgia Davis, Mary Pat Gallagher, Meenal Gupta, Manmohan Kamboj, Nicole Rioles, Emma Ospelt, Susan Thapa, Ruth S Weinstock, Trevon Wright, Osagie Ebekozien

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Healthy food prescription incentive programme for adults with type 2 diabetes who are experiencing food insecurity: protocol for a randomised controlled trial, modelling and implementation studies by Colleen Norris, Tyler Williamson, Richard Oster, Dana Lee Olstad, Laura White, David J T Campbell, Sharlette Dunn, Kim D Raine, Mary L'Abbé, Richard Lewanczuk, Lorraine L Lipscombe, Eldon Spackman, Reed Beall, Kienan Williams, Sara Scott, Gabrielle L Zimmermann, Kerry A McBrien, Kieran J D Steer, Catherine B Chan, Sheila Tyminski, Seth Berkowitz, Alun L Edwards, Terry Saunders-Smith, Saania Tariq, Naomi Popeski, Sara Nejatinamini, Aruba Naser, Carlota Basualdo-Hammond, Petra O’Connell, Judy Seidel, Jason Cabaj

“…Healthy food prescription programmes may reduce food insecurity and support patients to improve their diet quality, prevent diabetes complications and avoid acute care use. We will use a type 2 hybrid-effectiveness design to examine the reach, effectiveness, adoption, implementation and maintenance (RE-AIM) of a healthy food prescription incentive programme for adults experiencing food insecurity and persistent hyperglycaemia. …”
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“HEAL together”: a randomized, hybrid type 1 effectiveness-implementation trial protocol of a peer-delivered behavioral activation intervention to improve methadone treatment retention by Jessica F. Magidson, Jessica F. Magidson, Valerie D. Bradley, Jessica S. Anane, Mary B. Kleinman, Julia W. Felton, Abigail C. Hines, Rithika Baskar, Aaron D. Greenblatt, Dwayne Dean, Morgan S. Anvari, Heather Fitzsimons, Melanie E. Bennett, Annabelle M. Belcher

“…Building on a successful open-label pilot trial demonstrating initial feasibility, acceptability, and preliminary effectiveness of Peer Activate, the current type 1 hybrid randomized controlled trial evaluates the effectiveness of Peer Activate compared to treatment as usual on six-month methadone retention (primary) and longer-term implementation outcomes.MethodsThe trial is being conducted at a large methadone treatment program in Baltimore City, Maryland. …”
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Implementation of the novel multiple-input multiple-output power conversion system for applications in a micro-grid by R. Banupriya, R. Nagarajan, K.R.N. Kalis, J. Manjushree Kumari

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Addressing Hypertension and Diabetes through Community-Engaged Systems (ANDES) in Puno, Peru: rationale and study protocol for a hybrid type 2 effectiveness and implementation randomized controlled trial by Lindsay J. Underhill, Kendra N. Williams, Lucy Cordova-Ascona, Karina Campos, Lisa de las Fuentes, Mark D. Huffman, Joel Gittelsohn, Kenneth B. Schechtman, Zoila Vela-Clavo, Carla Tarazona-Meza, Laura K. Beres, Parker K. Acevedo, Abigail Barker, Nishadi Rajapakse, Makeda Williams, Veronica Tonwe, Aaloke Mody, Raquel Hurtado, Juan Carlos Mendoza, Gonzalo Cuentas, Elvin H. Geng, William Checkley, Victor G. Dávila-Román, Stella M. Hartinger-Peña

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Primary healthcare professionals’ awareness of management guidelines for type-2 diabetes mellitus and erectile dysfunction in Indonesia: a focus group discussion during the COVID-1... by Setho Hadisuyatmana, Gulzar Malik, Ferry Efendi, Sonia Reisenhofer, James H. Boyd

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For an Anthropology of Gaps, Discrepancies and Contradictions by Jean-Pierre Olivier de Sardan

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Expert consensus on solutions to improve implementation of NICE type 2 diabetes guideline (NG28) by health systems in England: a Delphi panel by the INNOVATE-28 Working Group by Partha Kar, Nazish Khan, Nicola Milne, Jim Moore, Waqas Tahir, Hannah Beba, Gail Fortes-Mayer, Sharvanu Saha, Marc Atkin

“…Objectives To provide expert consensus recommendations to support health systems in England to improve prioritisation and implementation of cardiovascular and renal risk-based type 2 diabetes (T2D) care, achieving quality improvement in line with the National Institute for Health and Care Excellence (NICE) NG28 guideline.Design A two-round modified Delphi panel was conducted.Setting Participants represented health system leadership from a cross-section of integrated care systems across England. …”
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Protocol of the TransformUs Secondary schools program: a type II hybrid implementation-effectiveness trial to increase adolescents’ physical activity and reduce sedentary time in secondary schools by Harriet Koorts, Anna Timperio, Jo Salmon, David Revalds Lubans, Gavin Abbott, Nicola D Ridgers, Natalie Lander, Ana María Contardo Ayala, Emiliano Mazzoli

“…The aim of this paper is to describe the protocol for TransformUs Secondary in relation to implementation and scale-up across Australia, and the real-world effectiveness of the intervention on adolescents’ physical activity and sedentary time, as well as sitting time, sleep, well-being and class and school engagement.Methods and analysis A type II hybrid implementation-effectiveness trial will be conducted using a mixed-methods design. …”
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Consistent implementation of decisions in the brain. by James A R Marshall, Rafal Bogacz, Iain D Gilchrist

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Translating implementation science principles and methods to front-line clinicians: The Implementation Science Scholars Program by Geoffrey M. Curran, Sara J. Landes, Taren Massey-Swindle, Benjamin S. Teeter, Cynthia L. Mosley, Jennifer Naylor, Laura P. James

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Assessing hospital antibiotic stewardship program (ASP) implementation: validation of an implementation science-informed survey by Jorie Michaela Butler, Ellen Childs, Tamar Barlam, Mari-Lynn Drainoni, Caitlin Reardon, Yue Zhang, Laura Damschroder, Peter Taber, Karl Madaras-Kelly, Matthew Goetz, Shana Burrowes, Eddie Stenehjem, Jincheng Shen, Chong Zhang, Angela Presson, Matthew Howard Samore

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NAGPRA in Archaeological Practice: Implementing Duty of Care by Jennifer R. Haas, Brooke Morgan, Ellen Lofaro, Jayne-Leigh Thomas, Sarah O’Donnell, Nina M. Schreiner, Miranda Panther

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The types of UNESCO library activities by Elena Macevičiūtė

“…This includes stating the rules in various fields of library work and implementing them through international conventions, as well as creating concepts for the development of libraries at both national and international levels…”
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