Development of a UHPLC-UV/Vis Method for Simultaneously Determining Six Beta-Lactam Antibiotics in Plasma: A Tool for the Clinical Implementation of Therapeutic Monitoring of Beta-... by Iria Varela-Rey, Marta Martínez-Guitián, Gonzalo Hermelo-Vidal, Enrique Bandín-Vilar, Ignacio Novo-Veleiro, Pablo Manuel Varela-García, Irene Zarra-Ferro, Miguel González-Barcia, Cristina Mondelo-García, Anxo Fernández-Ferreiro

“…<b>Background/Introduction:</b> Beta-lactam antibiotics are among the most frequently prescribed drugs in clinical practice, yet their therapeutic drug monitoring remains underutilized despite high interindividual pharmacokinetic variability, especially in critically ill patients. …”
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Optimizing wind energy conversion system efficiency using advanced modified super-twisting direct power control: Real-time implementation on dSPACE 1104 board by Mourad Yessef, Habib Benbouhenni, Ahmed Lagrioui, Youness El Mourabit, Nicu Bizon, Ilhami Colak, Badre Bossoufi, Ayman Alhejji

“…One of the most well-known nonlinear methods that is not based on the mathematical model of the wind conversion system is super-twisting control. …”
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Implementation of the Extension for Community Healthcare Outcomes Model for Hypertension Education of Frontline Health Care Workers in the Federal Capital Territory, Nigeria: Expla... by Abigail S Baldridge, Adaora Odukwe, Olabisi Dabiri, L Nneka Mobisson, Maria Moosa Munnee, Ayoposi Ogboye, Dorothy Naa Korkoi Aryee, Rodrick Mwale, Jonas Akpakli, Ikechukwu A Orji, Rosemary C B Okoli, Nanna R Ripiye, Dike B Ojji, Mark D Huffman, Namratha R Kandula, Lisa R Hirschhorn

“…ObjectiveThis study aims to evaluate implementation outcomes of the hypertension ECHO series mapped to the first 3 levels of the Kirkpatrick model. …”
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Outcomes and cost-effectiveness of an integrated holistic care package on persons affected by podoconiosis, lymphatic filariasis and leprosy and community members in north-western... by Oumer Ali, Awoke Mihretu, Natalia Hounsome, Vasso Anagnostopoulou, Stephen A. Bremner, Mersha Kinfe, Asrat Mengiste, Maya Semrau, Abebaw Fekadu, Gail Davey

“…Abstract Background Most studies on integration of neglected tropical disease programmes have focused on mass drug administration or environmental measures rather than Disease Management, Disability and Inclusion (DMDI). …”
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MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of co... by Anna Keravnou, Marios Ioannides, Charalambos Loizides, Kyriakos Tsangaras, Achilleas Achilleos, Petros Mina, Elena Kypri, Michael D Hadjidaniel, Maria Neofytou, Skevi Kyriacou, Carolina Sismani, George Koumbaris, Philippos C Patsalis

“…DNA methylation is the most characterized epigenetic process exhibiting stochastic variation across different tissues and individuals. …”
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A multicentre implementation trial of an Artificial Intelligence-driven biomarker to inform Shared decisions for androgen deprivation therapy in men undergoing prostate radiotherap... by Eric Wegener, Michael Ng, Mario Guerrieri, Timothy N. Showalter, Jeremy de Leon, Sagar Ramani, Marcus Dreosti, Tee Lim, Bradley Wong, Michael Chao, Kathryn Hogan, Avi Raman, Scott McClintock, Darren Foreman, Matthew Brown, Stephen McCombie, Kevin McMillan, Kieran Beattie, Mark Frydenberg, Lih-Ming Wong, Dickon Hayne, John Yaxley, Phillip Stricker, Jarad Martin

“…Clinical parameters alone are insufficient to accurately identify patients who will derive the most benefit, highlighting the need for improved patient selection tools to minimize unnecessary exposure to ADT’s side effects while ensuring optimal oncological outcomes. …”
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Progress on implementation of the World Health Organization global antimicrobial resistance surveillance system recommendations on antimicrobial resistance surveillance in Africa:... by Dr Mackline Hope, Dr Reuben Kiggundu, Mr Dickson Tabajjwa, Mr Fahad Lwigale, Mr Herman Mwanja, Dr Conrad Tumwine, Dr Jonathan Mayito, Dr Dathan M Byonanebye, Dr Andrew Kambugu, Dr Francis Kakooza

“…The World Health Organization (WHO) global antimicrobial resistance surveillance system (GLASS) was rolled out in 2016 to guide AMR surveillance systems. However, its implementation has not been fully evaluated. We conducted a scoping review of the current status of implementation of GLASS and present preliminary findings. …”
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Exploration of implementation, financial and technical considerations within allied health professional (AHP) telehealth consultation guidance: a scoping review including UK AHP pr... by Nachiappan Chockalingam, Nicola Eddison, Aoife Healy, Enza Leone, Carolyn Royse

“…Eight guidelines were obtained from the UK AHP professional bodies with a total of 29 included articles/guidelines. Most articles were published in the last two years; there was variety in telehealth terminology, and most were developed for occupational therapists, physiotherapists and speech and language therapists. …”
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Experiences and challenges in accessing hospitalization in a government-funded health insurance scheme: Evidence from early implementation of Pradhan Mantri Jan Aarogya Yojana (PM-... by Mayur Trivedi, Anurag Saxena, Zubin Shroff, Manas Sharma

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‘Involve those who are managing these outbreaks’: stakeholders’ perspectives on the barriers and facilitators to the implementation of clinical management guidelines for high-conse... by Olive Kabajaasi, Shevin T Jacob, Peter W Horby, Louise Sigfrid, Peter Hart, Mathias Akugizibwe, Stefan Schilling

“…Codes most strongly linked to facilitators and suggestions included: (1) HCW training in CMG implementation; (2) adequate resourcing; (3) involvement of personnel with prior HCID response experience in CMG development and (4) improvements in access to CMGs.Conclusions By illustrating linkages to resource constraints, healthcare disparities, and limited surveillance and referral infrastructure, our study displays how insufficient training, patchy dissemination and slow updating exacerbate many of the underlying difficulties for CMG implementation in LMIC contexts. …”
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Implementing Internet of Things for Real-Time Monitoring and Regulation of Off-Season Grafting and Post-Harvest Storage in Citrus Cultivation: A Case Study from the Hilly Regions o... by Ritu Raj Lamsal, Umesh K. Acharya, Periyasami Karthikeyan, Pablo Otero, Alfonso Ariza

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Knowledge, attitudes and preventive practices towards soil-transmitted helminthiases among teachers in schools implementing the home-grown school feeding program in Enugu Metropoli... by Daniel Chukwuemeka Obi, Blessing Hafizetu Nwazulu, Susan Chioma Udeh

“…This highlights that positive attitudes alone may not be sufficient for effective implementation of preventive measures. This underscores the need for targeted interventions, particularly tailored training for older and more experienced teachers. …”
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Perceived acceptability, barriers and enablers in implementing mobile phone messaging-based message-framing intervention for improved maternal and newborn care in Jimma Zone, Ethio... by Gebeyehu Bulcha, Zewdie Birhanu, Demisew Amenu, Hordofa Gutema

“…Mobile phone-based messaging was perceived as highly relevant and useful by most participants. However, many had limited prior experience using mobile messaging for health information. …”
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Expert consensus on solutions to improve implementation of NICE type 2 diabetes guideline (NG28) by health systems in England: a Delphi panel by the INNOVATE-28 Working Group by Partha Kar, Nazish Khan, Nicola Milne, Jim Moore, Waqas Tahir, Hannah Beba, Gail Fortes-Mayer, Sharvanu Saha, Marc Atkin

“…Panellists further agreed that investment should be channelled into community-led resources to reinforce a preventative approach and help to ensure people living with T2D receive care in the most appropriate setting. Finally, collaboration between health and social care, health innovation networks and industry partners was highlighted as an opportunity to leverage support for the delivery of risk-based T2D care.Conclusions The recommendations from this Delphi panel are intended to support health systems to consistently implement the NG28 guideline and facilitate quality improvement to deliver equitable T2D care and mitigate cardiovascular and renal risk. …”
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Efficient and Motion Correction-Free Myocardial Perfusion Segmentation in Small MRI Data Using Deep Transfer Learning From Cine Images: A Promising Framework for Clinical Implement... by German Garcia-Jara, Angel Jimenez-Molina, Esteban Reyes, Nicolas Tapia-Rivas, Cristobal Ramos-Gomez, Jose De Grazia, Matias Sepulveda

“…Deep learning-based methods, the most accurate to accomplish this task, still rely on expensive motion correction steps and require large labeled datasets. …”
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Implementing a General Practice-Based Link Worker Intervention for People with Multimorbidity During the Covid-19 Pandemic- a Mixed Methods Process Evaluation of the LinkMM RCT by Bridget Kiely, Ivana Keenan, Sonali Loomba, Natalie Mack, Vivienne Byers, Emer Galvin, Muireann O’Shea, Patrick O’Donnell, Fiona Boland, Barbara Clyne, Eamon O’Shea, Susan M. Smith, Deirdre Connolly

“…Despite most components of the intervention being delivered, the intervention was considered too short to support people with complex needs to connect with resources, particularly in the context of COVID-19 restrictions. …”
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Feasibility of implementing current best clinical practice for people who are using anabolic androgenic steroids within a Swiss primary care practice: a quality assurance study by Raphael Magnolini, Kuvinda Kossinna, Daniel Bjasch, Muriel Kruijver, Philip Bruggmann, Oliver Senn

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COVID-19 vaccine evidence monitoring assisted by artificial Intelligence: An emergency system implemented by the Public Health Agency of Canada to capture and describe the trajecto... by Su Hyun Lim, Mona Hersi, Ramya Krishnan, Joshua Montroy, Bonnie Rook, Kelly Farrah, Yung-En Chung, Adrienne Stevens, Joseline Zafack, Eva Wong, Nicole Forbes, April Killikelly, Kelsey Young, Matthew Tunis

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The importance and problems of applying the requirements of the International Audit Standards (ISA) in the private banks operating in the Kurdistan Region - Exploratory study by Ghazi O. Mahmood

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Exploring variation in the six-month review for stroke survivors: a national survey of current practice in England by Rich Holmes, Suzanne Ackerley, Rebecca J Fisher, Louise A Connell

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