Exploring potential drug targets for SLE through Mendelian randomization and network pharmacology. by Yanan Xu, Zelin Wang, Tiewen Jia, Shufen Liang

“…However, treatment varies by patient and disease activity, and existing medications for SLE were far from satisfactory. …”
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Advancing treat-to-target in SLE: a pilot study using a clinical decision support system by Ronald F van Vollenhoven, Koen Vos, Alexandre Voskuyl, Irene E M Bultink, Michel Tsang-a-Sjoe, Agner R Parra Sánchez, Odile van Hall

“…No statistically significant differences were observed between groups in disease activity outcomes or remission rates.Conclusions Implementation of a T2T strategy supported by a CDSS in SLE outpatient care was feasible, usable and acceptable to patients and physicians. …”
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Implementation of the Lupus Low Disease Activity State in Pediatric Rheumatology Care: The Role of the Visual Analog Scale by Ekemini A. Ogbu, Anna Carmela P. Sagcal‐Gironella, B. Anne Eberhard, Jennifer M. Huggins, Marisa S. Klein‐Gitelman, Karen Onel, Chen Chen, Bin Huang, Hermine I. Brunner

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The diagnostic and predictive potential of lncRNA CASC2 targeting miR-155 in systemic lupus erythematosus patients with nephritis complication by Nada R. Mohamed, Abeer l. Abd El-Fattah, Olfat Shaker, Ghadir A Sayed

“…Quantification of lncRNA CASC2 and miR-155 in serum samples from the Egyptian population was carried out with real-time polymerase chain reaction (RT-PCR). The disease activity index (SLEDAI) for SLE was evaluated, and the analysis of the receiver operating characteristic (ROC) curve was implemented. …”
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Effects of dual-task exercises on cognitive status, disease activity and quality of life in childhood-onset systemic lupus erythematosus by Ozgur Kasapcopur, Sezgin Sahin, Ela Tarakci, Eylul Pinar Kisa, Gokce Leblebici, İrem Yagmur Tonyali, Gulcin Balci, Şehri Dilek, Esma Aslan

“…Additionally, IPAQ median metabolic equivalent scores (3171.73±3185.69) were significantly increased after the intervention (5592.40±6228.61; p=0.01). Lupus disease activity score (SLEDAI-2K) decreased from 2.79±3.20 to 2.18±2.23 with the implementation of DT; however, this was not statistically significant (p>0.05).Conclusions DT exercises can play a crucial role in enhancing cognitive status and physical function of patients with cSLE. …”
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Study protocol for a randomized controlled trial to pilot Restore Energy, Activity Can Help (REACH): an mHealth-enabled peer coaching intervention for fatigue in systemic lupus ery... by Nina Gulati, Kiran Singh, Erin Morrissey, Priscilla Calvache, Jillian Rose-Smith, Monique Gore-Massy, Faye Chiu, Ludovic Trinquart, Iris Navarro-Millan, Sara Folta, Shanthini Kasturi

“…While physical activity interventions show promise in reducing SLE-related fatigue, they often fail to address these broader factors and are limited by accessibility challenges. …”
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Psychiatric Manifestations of Systemic Lupus Erythematosus Patients in a Tertiary Care Hospital: A Cross-sectional Study by Subhajit Mondal, Sourav Pradhan, Sayanti Ghosh, Arijit Sinha

“…Clinical significance: This study showed positive implications of implementing psychiatric rating scales as a screening tool in SLE patients for early diagnosis of psychiatric manifestations and use as corroborative measures of disease severity.…”
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Optimizing Lupus Care: Early Intervention to Prevent Organ Damage by Jose Alfredo Gómez Puerta

“…These case studies will provide practical insights into how this approach can be effectively implemented in clinical practice, showcasing its potential to alter the natural course of SLE by delaying organ damage and improving the quality of life for patients. …”
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Characteristics of Cerebral Cortical Structural Alterations in Female Patients with Systemic Lupus Erythematosus Without Major Neuropsychiatric Manifestations Accompanied by Anxiet... by Zhicheng Liu, Yifan Yang, Shuang Liu, Guofang Zhang, Ru Bai, Shu Li, Ruotong Zhao, Yuqi Cheng, Jian Xu

“…Methods: Employing advanced structural MRI (sMRI) techniques, we implemented a dual analytical approach combining voxel-based morphometry (VBM) and surface-based morphometry (SBM) to assess structural differences across three cohorts comprising 59 SLE patients with anxiety and/or depression (SLE-AD), 35 SLE patients with no anxiety and/or depression (SLE-NAD), and 48 age-matched healthy controls (HCs). …”
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The Impact of Self-Management Interventions on Behavioral and Clinical Outcomes in Individuals with Systemic Lupus Erythematosus: A Systematic Review of Empirical Evidence From 200... by Hanrop S, Narupan N, Praha N, Phianhasin L, Ruksakulpiwat S

“…Furthermore, the interventions contributed to an improved quality of life by addressing the physical, psychological, and social challenges faced by individuals with SLE.Conclusion: Self-management interventions positively impact behavioral and clinical outcomes in individuals with SLE. …”
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Formulation Development of Natural Polymeric Nanoparticles, In Vitro Antiaging Evaluation, and Metabolite Profiling of <i>Toona sinensis</i> Leaf Extracts by Uce Lestari, Muhaimin Muhaimin, Anis Yohana Chaerunisaa, Wawan Sujarwo

“…In this research, we implemented a development approach for chitosan–alginate and chitosan–pectin nanoparticles. …”
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The impact of 24-h movement behaviors on college students’ physical fitness and its isotemporal substitution benefits: a compositional data analysis approach by Rongxuan Li, Di Cui, Qingqing Fan, Le Zhao, Ziyao Xia, Tianer Zuo, Ye Qiu, Qing Jiang, Jiasheng Huo, Zuoliang Wang

“…The 24-h movement behaviors Questionnaire (24HMBQ) was administered to quantify five critical domains of daily movement patterns: sleep (SLE), sedentary behavior (SED), light physical activity (LPA), moderate physical activity (MPA), and vigorous physical activity (VPA). …”
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