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Establishing a new human pneumococcal standard reference serum, MPRSS-01
Published 2025-01-01“…Development of new pneumococcal conjugate vaccines (PCVs) with additional serotypes not in 007sp (e.g., V116, a 21-valent PCV) requires a new reference serum. Antibody concentrations to 33 pneumococcal serotypes were assigned in a new Merck Pneumococcal Reference Serum Standard (MPRSS-01; Merck Pneumococcal Reference Serum Standard) using the pneumococcal electrochemiluminescence assay. …”
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Human anti-D immunoglobulin preparations: potency standardisation milestones
Published 2022-10-01“…Human anti-D immunoglobulin preparations derived from human immune plasma are much needed and highly effective for specific anti-D prevention of perinatal complications and treatment of primary immune thrombocytopenia. …”
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Determination of reference values for TREC and KREC in circulating blood of the persons over 18 years
Published 2022-12-01“…Age, gender and ethnicity of patients may be significant factors of immunity. Hence, determination of the population reference intervals for TREC and KREC DNA excision rings in peripheral blood of adult persons is an urgent laboratory task for in-depth examination of both congenital and acquired immunodeficiency conditions. …”
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Self-Tuning Parameters of the Proposed Fuzzy Immune Integral Controller to Improve the Performance of the Standard P&O-MPPT Strategy
Published 2024-01-01“…Firstly, a nonlinear model perfectly describing the internal functioning of the solar PV generator is designed where its nonlinear current-voltage characteristic is linearized around standard test conditions (STC). The resulting RECS model is then used in a synthesis method that combines an immune control mechanism with fuzzy logic, where the parameters of the resulting controller are optimized using the Genetic Algorithm GA. …”
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Reference intervals for peripheral blood natural killer cell, monocyte, and dendritic cell subsets in healthy adults from Zhejiang province, China
Published 2025-07-01“…Abstract Background Given that immune cell profiles vary by region, age, and ethnicity, no standardized reference ranges currently exist for the proportions and absolute counts of natural killer (NK) cell, monocyte, and dendritic cell (DC) subsets in peripheral blood samples. …”
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Updated total IgE reference intervals in Norwegian adults
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Exploring the standardization of human nasal antibody measurements
Published 2025-12-01“…However, the current reference standard for nasal antibody assessment is serum-based, mainly consisting of monomeric IgG and IgA. …”
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Reference intervals for leukocyte cell population data in healthy adults in Zigong region, China
Published 2025-08-01“…Abstract Leukocyte cell population data (CPD), obtained through contemporary hematology analyzers, provide critical insights into the functional and morphological states of immune cells. However, clinically relevant reference intervals for these parameters remain scarce, particularly in region-specific populations. …”
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Immune monitoring and risk of infection in pediatric liver transplantation: a prospective study
Published 2025-06-01“…T, B and NK lymphocyte counts were adjusted for age using standard reference ranges.ResultsGraft rejection, post-transplant lymphoproliferative disorder and autoimmune hepatitis was diagnosed in 6%, 2% and 0% patients, respectively. …”
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Design, Implementation, and Evaluation of Proficiency Testing in EMC Burst Immunity
Published 2024-01-01“…For the accreditation according ISO/IEC 17025, the participation in the interlaboratory comparisons and proficiency testing is required as long as there exist suitable reference devices and providers. In order to contribute to the developments in this area, we have recently developed a new device, which can be used for the assessment of the test capabilities of laboratories for IEC 61000-4-4 (EFT/Burst Immunity). …”
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Herd Immunity to Hepatitis B in the Russian Federation in 2017–2019
Published 2022-05-01“…Assessment of the herd immunity to hepatitis B in the population of the Russian Federation in 2017‒2019.Materials and methods. …”
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Standard regulation of obligatory immunoprevention of flu in a control system of incidence of health workers
Published 2016-07-01“…By results of the analysis it is shown that today a problematic issue is absence of the accurate standardly consolidated criteria of reference of these or those categories of medical personnel to group of the subjects of obligatory immunization performing works with sick infectious diseases and, respectively, against flu. …”
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Research progress of immune checkpoint inhibitors in the treatment of glioblastoma
Published 2024-05-01“…Maximum surgical resection, chemotherapy and radiotherapy are currently the standard treatment for GBM. Due to the unique immune environment of the central nervous system, the application of immunotherapy in GBM is facing challenges. …”
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Transdermal influenza immunization with vaccine-coated microneedle arrays.
Published 2009-01-01“…In addition, the use of MN showed a dose-sparing effect and a strong Th2 bias when compared to an intramuscular (IM) reference immunization.<h4>Conclusions/significance</h4>The present results show that delivery of inactivated influenza virus through the skin using metal microneedle arrays induced strong humoral and cellular immune responses capable of conferring protection against virus challenge as efficiently as intramuscular immunization, which is the standard vaccination route. …”
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High-Accuracy HLA Type Inference from Whole-Genome Sequencing Data Using Population Reference Graphs.
Published 2016-10-01“…We conclude that HLA*PRG for the first time achieves accuracies comparable to gold-standard reference methods from standard whole-genome sequencing data, though high computational demands (currently ~30-250 CPU hours per sample) remain a significant challenge to practical application.…”
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Establishing Reference Values for Peripheral Blood Lymphocyte Subsets of Healthy Children in China Using a Single Platform
Published 2022-01-01“…We used the method of the international standard document (Clinical Laboratory Standard Institute C28-A3) to establish reference intervals with a single platform. …”
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The immunity-promoting activity of porcine placenta in mice as an immunomodulator for functional foods
Published 2022-11-01“…This investigation has provided a reference for the development of porcine placenta as a raw material applied in functional foods to improve human immunity.…”
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Evaluation of the immune response to diphtheria and tetanus toxoids by the serological methods
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Peripheral Blood Inflammation Indicators as Predictive Factors for Treatment Response Assessed by MRI in Cervical Cancer Patients Referred for Radiotherapy
Published 2023-03-01“…Backgroud: Radiotherapy (RT) with or without concurrent chemotherapy is regarded as the standard therapy for locally advanced cervical cancer (International Federation of Gynecology and Obstetrics [FIGO] stage IB2 and above). …”
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