Association of pan-immune inflammation value and lung health in adults by Ya Lin, Xiao Lin, Chufan Ren, Lanlan Song, Chao Gu

“…Subgroup analysis revealed variations in these associations stratified by gender, age, smoking and drinking status, as well as certain disease history. Conclusions The study highlighted the potential connections between PIV and respiratory symptoms, respiratory diseases and lung function. …”
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Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis. by Dequina Nicholas, Elizabeth A Proctor, Forum M Raval, Blanche C Ip, Chloe Habib, Eleni Ritou, Tom N Grammatopoulos, Devin Steenkamp, Hans Dooms, Caroline M Apovian, Douglas A Lauffenburger, Barbara S Nikolajczyk

“…Numerous studies show that mitochondrial energy generation determines the effectiveness of immune responses. Furthermore, changes in mitochondrial function may regulate lymphocyte function in inflammatory diseases like type 2 diabetes. …”
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Non-immune targeting of CXCR3 compromises mitochondrial function and suppresses tumor growth in glioblastoma by Travis Yui Hei Chan, Bo Chen, Wanjun Tang, Henry Hei Chan, Yogesh K. H. Wong, Ethan C. L. Wong, Junbo Liao, Anson Cho-Kiu Ng, Jenny Sum Yee Wong, Gilberto Ka-Kit Leung, Karrie M. Kiang

“…Abstract The chemokine receptor CXCR3 is traditionally recognized for its role in immune cell trafficking. However, emerging evidence suggests that its functions may extend beyond the immune system, particularly in cancer, where its roles remain to be elucidated. …”
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Immune, metabolic, anatomical, and functional features of people after successful tuberculosis treatment: an exploratory analysis by Tariq Webber, Candice Macdonald, Michele Tameris, Nicolette Tredoux, Anandi Bierman, Andrea Gutschmidt, Susanne Tönsing, Andriëtte Hiemstra, Firdows Noor, Candice Snyders, Tracy Richardson, Bernadine Fransman, Brian Allwood, Mark Hatherill, Leanie Kleynhans, André G. Loxton, Gerhard Walzl, Novel Chegou, Nelita du Plessis, Jane A Shaw, Stephanus T. Malherbe

“…The radiologic extent of structural post-TB lung involvement is associated with a range of impaired lung function measures and immunological dysregulation. …”
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Influence of puberty stage in immune-inflammatory parameters in well-trained adolescent soccer-players, following 8-weeks of pre-seasonal preparation training by Marios Hadjicharalambous, Eleanna Chalari, Nikolaos Zaras

“…A key limitation of this study is the lack analysis of lymphocyte subpopulations, which could provide a deeper understanding of the cellular effects of training on immune function.…”
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New insight of square stepping exercise in immune fine-tuning for anticipating emerging pandemics by Hyo-Jeong Cha, Changwan Hong

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MORPHOBIOCHEMICAL FUNCTIONS OF THE SHEEP ORGANISM AND THEIR ADJUSTMENT IN THE CONDITIONS OF IODINE DEFICIENCY by M. I. Selionova, A. K. Mikhailenko, L. N. Chizhova, C. B. Chotchaeva, E. S. Surzhikova

“…In this regard, the aim of this work was to study morphobiochemical changes, hormonal (thyroid) background, immune reactivity in Karachai sheep during ontogenesis in different ecological zones with different iodine availability levels as well as to consider the effect of exogenous hormone (thyroxine) on the immune status of young stock under conditions of iodine deficiency and determine promising ways of developing an effective method of prevention and treatment against the pathology.Methods. …”
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Computer-Assisted, Quantitative Cytokine Enzyme-Linked Immunospot Analysis of Human Immune Effector Cell Function by Yan Cui, Lung-Ji Chang

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Proteomic screening of human targets of viral microRNAs reveals functions associated with immune evasion and angiogenesis. by Amelia M Gallaher, Sudipto Das, Zhen Xiao, Thorkell Andresson, Philippe Kieffer-Kwon, Christine Happel, Joseph Ziegelbauer

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Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3. by Caroline L Wilson, Jelena Mann, Meagan Walsh, Maria J Perrugoria, Fiona Oakley, Matthew C Wright, Chiara Brignole, Daniela Di Paolo, Patrizia Perri, Mirco Ponzoni, Michael Karin, Derek A Mann

“…Toll-like Receptor 3 (TLR3) is a pathogen pattern recognition receptor that plays a key role in innate immunity. TLR3 signalling has numerous functions in liver, both in health and disease. …”
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DYRK1A in blood and immune function: implications in leukemia, inflammatory disorders, infection and Down syndrome by Esteban J. Rozen, Robin D. Dowell, Robin D. Dowell, Mary A. Allen

“…Here, we present a detailed review of the literature summarizing all the information linking DYRK1A to blood and immune function, as well as leukemia, inflammation and viral infections, with a special focus on their potential associations to T21. …”
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Effects of Low-molecular-weight Glycyrrhiza Polysaccharides on Immune Function, Gut Microbiota and Metabolites in Healthy Mice by Shengnan XUE, Wangdi SONG, Yunyun WANG, Yan ZHANG, Genlin ZHANG

“…Conclusion: Low-molecular-weight Glycyrrhiza polysaccharide achieved probiotic effects by enhancing the intestinal barrier function, tissue antioxidant capacity and immune response of healthy organisms, as well as changing the structure of gut microbiota and the types of metabolites.…”
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Application of Multidisciplinary Rehabilitation Nursing in Patients with Brucellar Spondylitis and Its Effects on Pain, Inflammation, and Immune Function by Zhang Y, Zuo X, Yang X, Li R, Wang H, Yu J, Yang X

“…However, patient satisfaction was significantly higher in the combined group (89.13%) than in the routine group (71.74%).Conclusion: Multidisciplinary rehabilitation nursing, when integrated with conventional care, significantly improves pain control, inflammatory response, immune function, emotional well-being, sleep quality, and spinal mobility in patients with brucellar spondylitis, without increasing adverse events, and results in higher patient satisfaction.Keywords: brucellar spondylitis, multidisciplinary rehabilitation nursing, effectiveness, pain, inflammation, immune function…”
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4-Octyl Itaconate Modulates Dendritic Cells Function and Tumor Immunity via NRF2 Activation by Zhu B, Zhu L, Ge Z, Zheng S, Dai X, Feng D, Tan L, Sha P, Yao Y

“…The protein level of NRF2 in BMDCs was analyzed by Western blot.Results: Treatment with 4OI represses DC maturation and function. Specifically, 4OI-treated DCs exhibited impaired phenotypic and functional maturation, characterized by decreased expression of co-stimulatory molecules CD40, CD80, and CD86, as well as lower levels of pro-inflammatory cytokines IL-12, IL-6, TNF-α and IL-1β. …”
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Immunosenescence and Inflammaging in Dogs and Cats: A Narrative Review by Brennen A. McKenzie

“…ABSTRACT A consistent and important feature of biological aging is the change in the types and functions of cells comprising the immune system. Across various mammalian species, this change follows consistent patterns, including diminished protective capacity, leading to increased vulnerability to infectious disease, and increased low‐grade chronic inflammation, raising the risk of numerous aging‐associated diseases. …”
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The effects of vitamin C supplementation on oxidative and immune response and post exercises inflammation by Aleksandra Durzyńska, Patryk Gutowski, Katarzyna Drozdowska, Katarzyna Żołądkiewicz, Agnieszka Słojkowska

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Impaired immune reconstitution in HIV infection: the role of CD4+ T-cell-associated NKG2D ligands, CD4+ T-cell subsets imbalance, and immune function deficiency by Qianqian Xu, Qianqian Xu, Qiuyue Zhang, Peng Xu, Peng Xu, Tong Zhang, Tong Zhang, Hao Wu, Hao Wu, Xin Zhang, Xin Zhang, Christiane Moog, Christiane Moog, Bin Su, Bin Su

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Function of 18F-FDG PET/CT radiomics in the detection of checkpoint inhibitor-induced liver injury (CHILI) by Clémence M. C. Huigen, Alexander Coukos, Sofiya Latifyan, Marie Nicod Lalonde, Niklaus Schaefer, Daniel Abler, Adrien Depeursinge, John O. Prior, Montserrat Fraga, Mario Jreige

“…Spleen PCA-5 differed significantly between CHILI and non-CHILI patients even after Bonferroni correction, possibly linked to the higher metabolic function of the spleen in autoimmune diseases due to the recruitment of immune cells. …”
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Functional immune reconstitution after allogeneic hematopoietic stem cell transplantation in myeloablative and non-myeloablative conditioned patients by Patrick Terrence Brooks, Lia Minculescu, Rebecca Svanberg Teglgaard, Hans Jakob Hartling, Jose Antonio Salado-Jimena, Lone Smidstrup Friis, Brian Kornblit, Ida Schjødt, Søren Lykke Petersen, Niels Smedegaard Andersen, Susanne Dam Nielsen, Jens Lundgren, Hanne Vibeke Marquart, Lars Klingen Gjaerde, Henrik Sengeløv, Sisse Rye Ostrowski

“…These comprise myeloablative (MA) conditioning consisting of chemotherapeutics often in combination with high-dose total body irradiation (TBI), while non-myeloablative (NMA) conditioning regimens use reduced dosage of chemotherapy and TBI allowing allo-HCT to patients who would otherwise not be eligible for treatment. While cellular immune reconstitution in allo-HCT patients has been well studied, differences between MA and NMA conditioned patients including the functional status of the immune system post-transplantation remains unclear. …”
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Influence of environmental exposures on T follicular helper cell function and implications on immunity: a comparison of Bangladeshi and American children by Dana M. Van Fossen, Hyunjae Cho, Lisa E. Wagar, Jennie Z. Ma, Julie Parsonnet, Rashidul Haque, Mark M. Davis, William A. Petri

“…ABSTRACT T follicular helper (Tfh) cells are crucial for B cell activation and subsequent antibody production. This functionality is influenced by surface markers such as CD40L, a costimulatory factor which promotes B cell activation, and CD57, which is a well-known marker of senescence. …”
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