High-dose intravenous immunoglobulin may be an efficient treatment option for patients with late-onset high-grade immune effector cell-associated hematotoxicity refractory to stand... by Yousef Laham, Shimrit Ringelstein-Harlev, Daniel Kurnik, Riva Fineman, Dana Yehudai-Ofir, Lilach Bonstein, Noga Setter-Marco, Eyal Braun, Itai Ghersin, Tsila Zuckerman, Ofrat Beyar-Katz

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Cost–benefit analysis of the National Immunization Program in Spain by Alberto Pérez, María Fernández Prada, Natalia Cassinello, Laura Amanda Vallejo-Aparicio, Andrea García, Almudena González, Ana Durán, Néboa Zozaya, Irene Fernández, Mathilde Daheron, Álvaro Hidalgo, Ekkehard Beck, Antonio García Ruiz

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Calcium Metabolism, Immunity and Reproduction in Early Postpartum Dairy Cows by Szilvia Kusza, Zoltán Bagi, Putri Kusuma Astuti, George Wanjala, Ottó Szenci, Árpád Csaba Bajcsy

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Impact of Immunosenescence on Immune‐Related Adverse Events in Elderly Patients With Cancer by Jiayi Gao, Yue Yuan, Xue Wang, Liuer He, Lin Li

“…ABSTRACT Immune checkpoint inhibitors (ICI), have transformed the management of several types of cancers; however, immune‐related adverse events (irAEs) may cause treatment interruptions, chronic toxic effects, and death. …”
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Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria by Stephanie I Studniberg, Lisa J Ioannidis, Retno A S Utami, Leily Trianty, Yang Liao, Waruni Abeysekera, Connie S N Li‐Wai‐Suen, Halina M Pietrzak, Julie Healer, Agatha M Puspitasari, Dwi Apriyanti, Farah Coutrier, Jeanne R Poespoprodjo, Enny Kenangalem, Benediktus Andries, Pak Prayoga, Novita Sariyanti, Gordon K Smyth, Alan F Cowman, Ric N Price, Rintis Noviyanti, Wei Shi, Alexandra L Garnham, Diana S Hansen

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Immune correlates of protection of the four-segmented Rift Valley fever virus candidate vaccine in mice by Chittappen K. Prajeeth, Isabel Zdora, Giulietta Saletti, Julia Friese, Thomas Gerlach, Lucas Wilken, Jana Beicht, Mareike Kubinski, Christina Puff, Wolfgang Baumgärtner, Jeroen Kortekaas, Paul J. Wichgers Schreur, Albert D.M.E. Osterhaus, Guus F. Rimmelzwaan

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Narcolepsy genetic variants associated with sleep efficiency in a community dwelling older cohort by Steven Jervis, Antony Payton, Altug Didikoglu, Arpana Verma, Kay Poulton

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Research Progress on Regulation of Tumor Immune Microenvironment via Reactivation of Unbalanced Mitochondria in Traditional Chinese Medicine by Mengying PENG, Lihong FAN, Changxing SHEN

“…Rebuilding damaged mitochondrial function, improving efficiency, and boosting the energy level of the neuro-endocrine-immune network are the key factors contributing to the body’s ability to resist disease and return to health.…”
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Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis by Lorenzo Braghieri, Ahmad Gharaibeh, Lubika Nkashama, Abdelrahman Abushouk, Osama Abushawer, Amir Mehdizadeh‐Shrifi, Bianca Honnekeri, Cassandra Calabrese, Venu Menon, Pauline Funchain, Patrick Collier, Diego Sadler, Rohit Moudgil

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Intratracheal instillation of RSV is superior to intranasal inoculation as a model method inducing critical immune cell infiltration by Yinglin Lin, Yao Xiao, Bin Peng, Mengyuan Xie, Zesen Mai, Mingzhen Lin, Shanshan Miao, Xinru Yang, Wei Li, Yi Wang, Zhaoyu Liu, Wenxia Yao

“…Collectively, our study offers novel insights into the rational design of future in vivo infection methods with RSV, as well as providing a foundation for the investigation of the immune pathogenesis of RSV.…”
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Effects of Three Different Bee Pollen on Digestion, Immunity, Antioxidant Capacity, and Gut Microbes in <i>Apis mellifera</i> by Xin-Meng Li, Ying Wang, Li Lei, Ge Zhang, Bao-Hua Xu

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Undernutrition disrupts jejunal and ileal microbiota and epithelial tissue homeostasis in a pregnant sheep model by Weibin Wu, Muhammad Faheem Akhtar, Jiahong Geng, Huizhen Lu, Muhammad Ajwad Rahim, Jianbo Cheng, Xiaoling Ding, Shengyong Mao, Yanfeng Xue

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Probing aspects of extracellular vesicle associated AAV allows increased vector yield and insight into its transduction and immune-evasive properties by Ming Cheng, Demitri de la Cruz, Adam V. Crain, Paula Espinoza, Carrie Ng, Zachary C. Elmore, Aravind Asokan, Casey A. Maguire

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In Vitro Characterization of the Immune Response to an Epitope Ensemble Vaccine Against Rhinovirus in Pediatric Asthma and Adults With Chronic Obstructive Pulmonary Disease: Protoc... by Sara Alonso Fernandez, Raquel Reyes-Manzanas, Susana Camara, Juan Mozas-Gutierrez, Myriam Calle-Rubio, Juan Rodriguez-Hermosa, Andres Bodas-Pinedo, Santiago Rueda Esteban, Esther M Lafuente, Jesús Reiné, Pedro A Reche

“…A detailed characterization of these immune responses will provide critical insights into host-pathogen interactions and may serve as a foundation for the development of effective T-cell–based vaccines or immunotherapies targeting HRV. …”
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Microneedle patches with antimicrobial and immunomodulating properties for periodontal regeneration by Boyuan Wang, Heyi Gong, Yang Jiang, Aizhuo Song, Junqi Wang, Minghe Li

“…Periodontitis is a widespread chronic inflammatory disorder resulting from bacterial infection combined with immune response dysregulation, typically characterized by alveolar bone destruction and subsequent tooth displacement or loss. …”
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Extraction, structural characterization, and in vitro immunomodulatory activities of Saccharomyces cerevisiae spore wall β-glucan by Mengqing Yan, Xue Wang, Jingtao Zhang, Shuheng Yang, Cong Pan, Shiwei Liu, Jia Liu, Youqiang Yu, Fangli Ding, Shenglin Duan, Huoqing Huang, Guoyu Liu, Peng Yuan

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Generation of IgM+ B cell-deficient Atlantic salmon (Salmo salar) by CRISPR/Cas9-mediated IgM knockout by Mari Raudstein, Ma. Michelle D. Peñaranda, Erik Kjærner-Semb, Søren Grove, H. Craig Morton, Rolf Brudvik Edvardsen

“…This work presents the first application of CRISPR/Cas9 to disrupt an immune-related gene in the F0 generation of Atlantic salmon, and lays the foundation for generating a model completely lacking IgM+ B cells which can be used to study the role of B cells and antibodies. …”
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The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases by Yezhou Ding, Mingyang Feng, Wanqing Chi, Xiaoyin Wang, Baoyan An, Kehui Liu, Shike Lou, Xiaolin Wang, Hui Wang

“…Ultimately, we constructed a METTL17-related risk-score model of HCC and validated its prognostic classification efficiency. Survival rates were calculated using the Kaplan-Meier method. …”
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Insights into IAV Replication and Lipid Metabolism in Suspension-Adapted MDCK-STAT1-KO Cells by Qian Ye, Hong Yao, Zhiying Xiao, Liang Zhao, Wen-Song Tan

“…These insights provide a foundation for the development of more efficient vaccine production platforms, with implications for large-scale industrial applications.…”
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Sustainability starts with spending: public financial management lessons from Kenya’s universal health care pilot by Alex Olateju Adjagba, James Odhiambo Oguta, Catherine Akoth, Solomon Kimutai Toweet, Peter Okoth, Debra Jackson

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