Advancing treatment choices: CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer by Paola Zagami, Angela Esposito, Beatrice Taurelli Salimbeni, Pier Paolo Maria Berton Giachetti, Roberta Scafetta, Matteo Lambertini, Massimo Di Maio, Giuseppe Curigliano, Carmen Criscitiello, Saverio Cinieri

“…Purpose: CDK4/6 inhibitors (CDK4/6i) use has revolutionized the treatment of hormone receptor-positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) metastatic breast cancer. …”
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BUDGET USE AND PERFORMANCE OF MANUFACTURING SMALL AND MEDIUM ENTERPRISES (SMEs) IN LAGOS STATE, NIGERIA by Mubaraq Sanni, Oladipo Oluwafolakemi Fasesin

“…The population of the study was 46,652 managers (Managing Director, Account Manager, Human Resources Manager and Production/operation Manager) of manufacturing SMEs operating in Lagos State out of which 397 were randomly selected. …”
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Knowledge, attitude and practice of health care workers on solid medical waste management in two urban hospitals of Bangladesh: a mixed-method study by Md Tauhidul Islam, Md Abdur Rafi, Mohammad Jahid Hasan

“…Poor knowledge and attitude were the major barriers for proper waste management in IDH while lack of funds, human resource and logistics were the major barriers in DSH. …”
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Particulate matter concentrations and health risks associated with cow hides singeing in Abattoirs in Benin City, Nigeria by Aimuanmwosa Frank Eghomwanre, Gracious Oghosa Edomwonyi

“… Introduction: The singeing of animals is one of the major sources of human exposure to air pollutants in abattoirs especially in developing countries and it can cause various adverse health effects among the workers. …”
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Antimicrobial and ADME properties of methoxylated, methylated and nitrated 2-hydroxynaphthalene-1 carboxanilides by Lucia Vrablova, Tomas Gonec, Tereza Kauerova, Michal Oravec, Izabela Jendrzejewska, Peter Kollar, Alois Cizek, Josef Jampilek

“…All the compounds were evaluated for antibacterial activities against Gram-positive and Gram-negative bacteria and mycobacteria. Cytotoxicity on human cells was also tested. Key results: Three compounds showed activity comparable to clinically used drugs. …”
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Investigasi Hambatan dan Tantangan Penerapan Sistem Informasi Manajemen di Rumah Sakit by Malahayati Malahayati, Dedy Syamsuar

“…Based on the domain analysis, the research identifies several problems that are the causes, namely poor infrastructure, commitment to human resources (HR), standard operating procedures (SOP) that have not been implemented, clarity of main tasks and functions, as well as ineffective supervision, supervision from parties. management that is not implemented as well as external systems as the cause of not optimal hospital management information system. …”
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Comparative study of packaging materials developed from fish and legume protein concentrates by Evmorfia Athanasopoulou, Angeliki Katsiroumpa, Chrysavgi Gardeli, Theofania Tsironi

“…All produced films biodegraded in <20 days during burial test in soil with high relative humidity (80 %). The results of the study show the utilization of food industry potential waste for producing environmentally friendly packaging materials.…”
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Comparison of algorithms for the recognition of ChatGPT paraphrased texts by Aleksandar Kartelj, Miljana Mladenović, Staša Vujičić Stanković

“…Both datasets were subjected to ChatGPT paraphrasing, which allowed us to form two classes of texts: human-written and AI-generated, i.e., AI-paraphrased. …”
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Association of ambient temperatures with suicide attempts and violence with the future projections under climate change scenarios: a nationwide time-stratified case-crossover study... by Jiwoo Park, Jieun Oh, Whanhee Lee, Yeonsu Kim, Jeong Ho Park, Ho Kim, Seungsik Hwang

“…Abstract Background Both climate change and intentional injuries (suicide attempts and violence) are recognized as crucial factors that affect human health. Previous studies revealed the association between ambient temperatures and deaths due to intentional injuries but mostly about the consequences of severe events. …”
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Pollution Characteristics and Source Analysis of Carbonaceous Components in PM2.5 in a Typical Industrial City by Liyan Ma, Dongmei Hu, Yulong Yan, Yueyuan Niu, Xiaolin Duan, Yafei Guo, Wanhua Li, Lin Peng

“…Abstract Carbonaceous components are important components of fine atmospheric particulate matter (PM2.5) and can affect the local environment, climate, and human health. In this study, online observation data from September 1, 2022, to August 31, 2023, were used to analyze the carbonaceous components, namely, organic carbon (OC) and elemental carbon (EC), in PM2.5 in Jincheng, which is a typical industrial city. …”
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Composition Characteristics and Potential Regions of PM2.5 during Winter Haze Pollution in Typical Industrial Areas, NW-China by Liyao Guo, Chao Gu, Kaiyuan Dong, Shengju Ou, Xueyan Zhao, Xinhua Wang, Zhensen Zheng, Wen Yang

“…The increased pollution, combined with high relative humidity (RH) increased the liquid water content (LWC), which in turn promoted heterogeneous reactions. …”
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Contributions of Biomass Burning and Other Sources to Fine Particle Level and Oxidative Potential in Suburban Tokyo, Japan by Akihiro Fushimi, Ana M. Villalobos, Akinori Takami, Kiyoshi Tanabe, James J. Schauer

“…Abstract Fine particulate matter (PM2.5) in the atmosphere is of high priority for air quality management efforts due to well-established associations with adverse effects on human populations. To develop effective countermeasures against PM2.5 emission sources, its origin needs to be efficiently characterized. …”
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Seasonal Particle Size Distribution and its Influencing Factors in a Typical Polluted City in North China by Wenxin Wang, Xiaohua Wang, Xue Li, Chao Chen, Yu Wang, Zhiwen Xing, Kun Li, Min Wei, Xiao Sui, Houfeng Liu

“…Pearson and generalized additive model (GAM) analysis indicated PM2.5 was positively correlated with relative humidity (RH), CO, NO2, SO2, and PM2.5-10 concentrations, negatively correlated with wind speed, O3 and coarse particles (PM>10) concentrations. …”
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The Unignorable Near-ground PM2.5, UFP, PAHs, and BC Levels around a Traffic Prohibited Night Market by Sheng-Lun Lin, Hongjie Zhang, Ming-Yeng Lin, Shih-Wei Huang

“…Abstract In some special densely populated areas, the background atmospheric fine particulate matter (PM2.5) concentration is very high, which makes near-ground (NG) exposure a major problem endangering human health. In our study, the night market in Chiayi City was selected as the research object and collected the 24-hour PM2.5 samples through the federal reference method (FRM), characterizing the mass concentration, water-soluble ionic components, carbon specious, metal compositions and source contributions of PM2.5. …”
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The record-breaking precipitation event of December 2022 in Portugal by T. M. Ferreira, T. M. Ferreira, R. M. Trigo, T. H. Gaspar, J. G. Pinto, A. M. Ramos

“…<p>Extreme precipitation events (EPEs) potentially present an enormous societal risk and often lead to major human and economic impacts. In the mid-latitudes, such EPEs are often triggered by intense extratropical cyclones and their associated frontal systems. …”
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Modeling optimal combination of breast and cervical cancer screening strategies in China by Xuewei Liu, Yanbo Wang, Bei Gao, Xinlin Lu, Yuan Wang, Wenli Lu

“…Results The optimal combination strategy was biennial breast ultrasonography (BUS) and mammography (MAM) in parallel screening and quinquennial human papillomavirus (HPV) for breast and cervical cancer screening under the threshold of the annual per capita social cost investment (PCSCI) (18.80 USD) in China. …”
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CircSPG21 ameliorates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells and mitigates intervertebral disc degeneration through the miR-217/SIRT... by Yongbo Zhang, Sheng Yang, Xuan You, Zhengguang Li, Liuyang chen, Rui Dai, Hua Sun, Liang Zhang

“…Results CircSPG21 expression was significantly decreased in both human and rat IVDD tissues, whereas miR-217 was upregulated and SIRT1 was downregulated. …”
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Level of Pollution of Water from River Rwabakazi Indicated by Metal Ions and Suspended Solids Concentrations. by Habimana, Michael

“…The concentrations decreased downstream as follows; iron (II) from 60.04 to 54.40 mg/L; iron (Ill) from 19.50 to 16.50 mg/L; calcium from 99.00 to 68.00 mg/L; magnesium from 7 .20 to 6.00 mg/L and TSS from 15.6 to 10.5 mg/Lall of which exceeded the allowed limits by EPA and WHO guidelines for safe water for human use. The available data can be relied on to assert that river Rwabakazi is polluted as a result of erosion and flush flooding but has capacity to undergo natural self-purification although very slowly. …”
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Carpolobia lutea methanol root extract reinstates androgenesis and testicular function in cadmium- challenged rats by Ejike, Daniel Eze, Okpa, Precious Nwaka, Igbokwe, Ugochukwu Vincent, Moses, Dele Adams, Karimah, Mohammed Rabiu, Ayikobua, Emmanuel Tiyo

“…Cadmium produces a wide range of biological dysfunctions in human and laboratory animals where it chiefly affects the testes, whereas, Carpolobia lutea has been known to have antioxidant benefits. …”
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Design of a Flexible Pavement For Nyakabande–Mutolere Road, Nyakabande Sub County, Kisoro District. by Habimana, Stephen

“…Besides the 94% of road accidents being caused by human error, poor driving road surfaces which result from inadequate and premature pavement deteriorations, are responsible for various accident reports in the country, Uganda. …”
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