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  1. 3241

    MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway by Zigui Chen, Chao Liu, Wei Zheng, Zhilong Li, Yuanhui Tang, Jun Peng, Changfeng Miao, Dandan Zheng, Ying Xia

    Published 2025-02-01
    “…EMT is involved in multiple physiological and pathological processes in the human body. The occurrence of EMT involves many signal transduction pathways and complex molecular mechanisms related to calnexin, growth factors, transcription factors, and the microenvironment. …”
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    Article
  2. 3242

    Fine Particulate Matter Deposition in 3D Out-of-Plane Bifurcation Lung Airway by Chun-Chih Chuang, Justus Kavita Mutuku, Chih-Che Chueh, Anurita Selvarajoo, Wei-Hsin Chen

    Published 2023-04-01
    “…While the in-plane airway structures of human lungs are usually used in numerical models, a 3D out-of-plane layout that can geometrically represent triple bifurcations airways of the so-called Weibel model is developed in the present study with the presence of fine particles inside. …”
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  3. 3243

    Assessment of forest soil contamination by heavy metals in the Polish National Park near Warsaw by Aneta Łukaszek-Chmielewska, Joanna Rakowska, Marzena Rachwał, Olga Stawarz

    Published 2025-02-01
    “…Abstract The forest ecosystems are essential for human well-being development and reduction of the risk of natural disasters. …”
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    Article
  4. 3244

    Preschoolers' prosocial behavior in groups—Testing effects of dominance, popularity, and friendship by Anne Katerkamp, Lisa Horn

    Published 2025-02-01
    “…Prosocial, other-benefitting behavior is a fundamental aspect of human social behavior. In the microsystem of their natural social groups, preschool children have to decide not only whether, but also whom to share with and help on a daily basis. …”
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    Article
  5. 3245

    The influence of weather and urban environment characteristics on upper respiratory tract infections: a systematic review by Henna Hyrkäs-Palmu, Henna Hyrkäs-Palmu, Timo T. Hugg, Timo T. Hugg, Jouni J. K. Jaakkola, Jouni J. K. Jaakkola, Tiina M. Ikäheimo, Tiina M. Ikäheimo, Tiina M. Ikäheimo

    Published 2025-02-01
    “…Low temperature (11/19 studies) was most often associated with increased risk of RTI. Humidity showed either negative (5/14 studies), positive (3/14 studies) or no (6/14 studies) relation with RTIs. …”
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    Article
  6. 3246

    Molecular investigation on active compounds in papaya leaves (Carica papaya Linn) as anti-malaria using network pharmacology, molecular docking, clustering-based analysis and molec... by Arwansyah Arwansyah, Sitti Rahmawati, Siti Nuryanti, Yenni Yusuf, Hartono, Abdur Rahman Arif

    Published 2025-02-01
    “…A total of 23 proteins linked to the active compounds and malaria-related targets in human proteins were identified using network analysis. …”
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    Article
  7. 3247

    CCL21-CCR7 blockade prevents neuroinflammation and degeneration in Parkinson’s disease models by Felipe Saceanu Leser, Flavio de Souza Júnyor, Iohanna Bianca Pagnoncelli, Anna Beatriz Delgado, Isabelle Medeiros, Ana Clara Campanelli Nóbrega, Brenda da Silva Andrade, Maiara Nascimento de Lima, Nícolas Emanoel da Silva, Laurent Jacob, Kevin Boyé, Luiz Henrique Medeiros Geraldo, Alessandra Mendonça Teles de Souza, Tatiana Maron-Gutierrez, Hugo Castro-Faria-Neto, Cristian Follmer, Carolina Braga, Gilda Angela Neves, Anne Eichmann, Luciana Ferreira Romão, Flavia Regina Souza Lima

    Published 2025-02-01
    “…Herein, we identified the neuronal chemokine CCL21 as a major cause of microglial cell imbalance through the CCR7 receptor pathway with therapeutic implications for PD. In humans, we found that CCL21 transcript expression was increased in dopaminergic neurons (DANs) of the substantia nigra in PD patients. …”
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    Article
  8. 3248

    Secretory phospholipase A2 inhibitory activity in Tragia hispida: A novel and promising therapeutic agent for dengue fever by D.V. Dayangi Hemalika, U.G. Chandrika, Ajita M. Abeysekera, Sameera R. Samarakoon, Ananda Wijewickrama, Gathsaurie Neelika Malavige

    Published 2025-02-01
    “…Furthermore, THB exhibited significant inhibition of sPLA2 activity in human serum from dengue patients (n = 31, p < 0.0001) than that exhibited by CAY 10590. …”
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  9. 3249

    Clinicopathological characteristics and long-term prognosis of triple-negative breast cancer patients with HER2-Low expression: a retrospective propensity score-matched cohort stud... by Xin Liu, Kaihua Zhao, Ziyan Zhang, Meiyan Liu, Hongwu Chu, Xiao Zou

    Published 2024-12-01
    “…Abstract Purpose The objective of the current research was to assess the clinicopathological characteristics and long-term prognosis of triple-negative breast cancer (TNBC) patients with human epidermal growth factor receptor 2 (HER2)-low status following breast surgery. …”
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  10. 3250

    Impact of copper stress in the intestinal barriers and gut microbiota of Chinese stripe-necked turtle (Mauremys sinensis) by Zeeshan Ali, Ijaz Khan, Muhammad Shahid Iqbal, Haitao Shi, Li Ding, Meiling Hong

    Published 2025-01-01
    “…Copper stress caused intestinal damage, characterized by shortened villi, inflammatory cell infiltration, and reduced epithelial layer thickness, as well as decreased acidic mucins, increased villi edema and inflammation. The mRNA expression level of bacteriostatic enzymes significantly reduced. …”
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  11. 3251

    A systematic review of neurological symptoms and brain abnormalities in SARS-CoV-2 infections by Daniel Montoya, Jacobo Albert, Sarah Lopez-Martin

    Published 2023-08-01
    “… The aim of this systematic review is to show some clear evidence of COVID-19 infections in the human brain and draw attention to the neurological symptoms that were described during the early stages of the pandemic. …”
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    Article
  12. 3252

    Primordial Cause of Armament, Disarmament, Weaponry and Weapons of Mass Destruction by Effiong Ekpo

    Published 2022-11-01
    “… The entirety of humanity has been confronted with a serious threat to security, especially since after the cold war. …”
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    Article
  13. 3253

    Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial by Xue Gao, Lu Liu, Mei-Rong Pan, Hai-Mei Li, Yu-Feng Wang, Xue-Ying Liu, Zhong-Fang Fu, Qiujin Qian

    Published 2025-02-01
    “…The findings may contribute to providing an effective and feasible transdiagnostic intervention in Chinese clinical settings.Ethics and dissemination This trial has been approved by the Ethics and Clinical Research Committees of Peking University Sixth Hospital and will be performed under the Declaration of Helsinki with the Medical Research Involving Human Subjects Act (WMO). The results will be disseminated in a peer-reviewed journal and a conference presentation.Trial registration number ChiCTR2300069354.…”
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  14. 3254

    A traffic prediction method for missing data scenarios: graph convolutional recurrent ordinary differential equation network by Ming Jiang, Zhiwei Liu, Yan Xu

    Published 2025-01-01
    “…Due to various factors, both human and natural, traffic data often contains missing values. …”
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  15. 3255

    Assessment of the Preservation and Conservation of Teachers’ Records at Rubanda District Local Government by Gumoshabe, Alexander R.

    Published 2023
    “…The findings of the study revealed that, biological threats, mishandling of records, dust, humidity, fungi, pests and moulds, pollution, plucking of pages of documents and poor retrieval and filling practices are leading causes of deterioration of teachers records.…”
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  16. 3256

    Content and Dynamics of Nutrients in the Surface Water of Shallow Lake Mulehe in Kisoro District, South–western Uganda. by Saturday, Alex, Kangume, Susan, Bamwerinde, Wilson

    Published 2023
    “…The recorded overall WQI value places Lake Mulehe’s water quality into the ‘poor’ category in terms of worthiness for human consumption. The study, therefore, recommends continuous pollution monitoring and enforcement of local regulations to reduce pollution in the lake as a result of anthropogenic activities.…”
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    Article
  17. 3257

    An Investigation into Information Security Managerial Practices in Selected Public Sector Organizations. by Ahimbisibwe, Benjamin K., Nabende, Peter, Musiimenta, Florence

    Published 2023
    “…Focus was made on information security practices critical to managing information like human security, information classification, procedures for information labelling, compliance, standards, command and control techniques. …”
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    Article
  18. 3258

    Community Development in the Rural Areas through Traditional Indigenous Knowledge by Godfrey, Barigye, Siraje, Kaaya

    Published 2019
    “…This progressive change is synonymous with sustainable development designed to improve the economic and social means that the total stock of environment (resources) be put into use in socio-economic and other related aspects to satisfy human needs.…”
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  19. 3259

    The Impact of Covid-19 Pandemic on Women: A Case Study of Northern Division Kabale Municipality Kabale District. by Ankunda, Tomson

    Published 2024
    “…This is because they need to be adequately supported with human and financial resources, but without reducing resources from women's programs.…”
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    Thesis
  20. 3260

    Content and dynamics of nutrients in the surface water of shallow Lake Mulehe in Kisoro District, South–western Uganda by Saturday, Alex, Kangume , Susan, Bamwerinde, Wilson

    Published 2024
    “…The recorded overall WQI value places Lake Mulehe’s water quality into the ‘poor’ category in terms of worthiness for human consumption. The study, therefore, recommends continuous pollution monitoring and enforcement of local regulations to reduce pollution in the lake as a result of anthropogenic activities.…”
    Get full text
    Article