Desmoplastic reaction in the microenvironment of head and neck and other solid tumors: the therapeutic barrier by Kohei Okuyama, Maiko Tsuchiya, Kala Chand Debnath, Shajedul Islam, Souichi Yanamoto

“…The interaction between cancer-associated fibroblasts (CAFs) and TME influences immune responses, including resistance to immunotherapy. Notably, human papillomavirus-driven HNSCC exhibits distinct DR characteristics that further influence the prognosis. …”
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INTERNATIONALIZATION OF CONFLICT AS A CHALLENGE TO PEACE AND DEVELOPMENT IN AFRICA by ANTHONY IMEH UMOH, BARINAADAA NWINKOL

“…It has eroded to a larger extent the core value of human existence in the continent. The depended nature of African economy is largely blame for this, knowing fully well that whatever affects he developed nations have a rippling effect on Africa. …”
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Resveratrol, a food-derived polyphenol, promotes Melanosomal degradation in skin fibroblasts through coordinated activation of autophagy, lysosomal, and antioxidant pathways by Saki Okamoto, Saya Kakimaru, Mayuko Koreishi, Mika Sakamoto, Yoshimasa Nakamura, Hideya Ando, Yoshio Tsujino, Ayano Satoh

“…We investigated resveratrol's ability to enhance melanosomal degradation in human dermal fibroblasts. At concentrations of 25–50 μM, resveratrol increased autophagy as measured by microtubule-associated protein 1A/1B-light chain 3 (LC3)-II/LC3-I ratio and enhanced lysosomal activity as assessed by a lysosomal activity reporter system. …”
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Chemical compositions and health promoting effects of edible mushrooms from genus Russula by Xinwen Hu, Baojun Xu

“…Conclusion: Further research is warranted to uncover the underlying mechanisms of action and fully realize the clinical potential of Russula mushrooms in promoting human health and well-being.…”
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Integrating Legal Protection Strategies for Wife and Children Due to Rejection of Marriage Isbat Application by Abdul Jalil, Abdul Haq Syawqi, M. Haris Hidayatulloh, Umi Supraptiningsih, Cut Linda Marheni

“…Normatively, the way that can be taken is by integrating several aspects such as aspects of the law, law enforcement, and facilities or facilities that can support the application of law, such as human resources and sophisticated tools such as tools to find out a person's DNA. …”
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THE TOURISM POTENTIAL AND EFFECTIVE MANAGEMENT OF RURAL HERITAGE ASSETS THROUGH THEME ROUTES by Tibor Gonda, Monika Pentz

“…The past, which cannot be erased from human memory, is also a resource that is constantly renewed. …”
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Mapping naturally presented T cell antigens in medulloblastoma based on integrative multi-omics by Julia Velz, Lena K. Freudenmann, Gioele Medici, Marissa Dubbelaar, Malte Mohme, David R. Ghasemi, Jonas Scheid, Daniel J. Kowalewski, Angelica B. Patterson, Anna M. Zeitlberger, Katrin Lamszus, Manfred Westphal, Matthias Eyrich, Martina Messing-Jünger, Andreas Röhrig, Harald Reinhard, Kévin Beccaria, Rogeiro B. Craveiro, Beat M. Frey, Martin Sill, Sven Nahnsen, Marie Gauder, Konstantina Kapolou, Manuela Silginer, Tobias Weiss, Hans-Georg Wirsching, Patrick Roth, Michael Grotzer, Niklaus Krayenbühl, Oliver Bozinov, Luca Regli, Hans-Georg Rammensee, Elisabeth J. Rushing, Felix Sahm, Juliane S. Walz, Michael Weller, Marian C. Neidert

“…Here, we present an atlas of naturally presented T cell antigens in medulloblastoma. We map the human leukocyte antigen (HLA)-presented peptidomes of 28 tumors and perform comparative immunopeptidome profiling against an in-house benign database. …”
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Pantropical Jumping Spiders in Florida by Glavis B. Edwards, Jr.

“…All jumping spiders are harmless to humans, although the larger species can give a locally painful bite if roughly handled. …”
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Techniques for Suppressing Mineral Dust Aerosol from Raw Material Stockpiles and Open Pit Mines: A Review by Hsin-Chieh Kung, Wan-Ching Lin, Bo-Wun Huang, Justus Kavita Mutuku, Guo-Ping Chang-Chien

“…Nevertheless, there is skepticism about adopting hybrid surfactants due to insufficient knowledge of environmental impacts and hazards to human health.…”
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Enhancing Smart City Maturity Through Digital Transformation: A Success Factors Analysis by Widya Listianingsih, Tony Dwi Susanto

“…The study results reveal six factors influencing Smart City maturity: Information and Communication Technology (ICT) infrastructure, data integration, government policies and strategic planning, stakeholder engagement, environmental sustainability, and innovation and human resource development. Unlike previous studies, this study synthesizes global best practices and success factors, offering actionable insights for policymakers and practitioners to design inclusive, sustainable, and forward-looking digital transformation strategies. …”
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Accurate identification of oxygen desaturation status in COPD by using classifier ensemble. by Yue-Fang Wu, Xin Shu, Shiqi Wang, Xiaojun Xu, Pei-Li Sun

“…The accurate identification of oxygen desaturation (OD) status plays critical role in the clinic diagnosis of chronic obstructive pulmonary disease (COPD), which is a common disease related to the lungs and respiratory tract of the human body. This paper focuses on a specific type of OD status, i.e., exercise-induced oxygen desaturation (EIOD) status in COPD, and try to further improve the performance of EIOD status identification. …”
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Hyper-resolution naturalized streamflow data for Geum River in South Korea (1951–2020) by Byeong-Hee Kim, Young-Oh Kim, Jonghun Kam

“…However, 36% of the stations show low modified Kling-Gupta Efficiency (0.2–0.4), primarily due to uncertainties in runoff data and human disturbance impacts like irrigation and reservoir storage. …”
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Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin by Jingtao Wu, Yonghui Xia, Tianyu Wang, Yafeng Zhang, Guangli Li

“…The applicability of MIP/BPNS-AgNP/GCE toward the detection of GAT in pharmaceutical formulations, milk, and human serum was verified with satisfactory results.…”
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"He Has Rescued Me from Danger" by Sarah Bishop

“…All point to the same phenomenon: that music can play a role in human resilience and meaning-making. Finally, I make suggestions on how to enhance mental health care in culturally-relevant ways in a religious society such as in Ethiopia, as well as draw out cross-cultural implications for mental health care in the western system. …”
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Datos sobre los Carbohidratos by Nancy J. Gal, Amanda L. Ford, Wendy J. Dahl

“…Dahl, and published by the UF Department of Food Science and Human Nutrition, July 2014. FSHN14-03s/FS250: Datos sobre los Carbohidratos (ufl.edu) …”
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NF-κB Inhibitory Activity of the Di-Hydroxy Derivative of Piperlongumine (PL-18) by Yael Schlichter Kadosh, Subramani Muthuraman, Ariel Kushmaro, Rajendran Saravana Kumar, Jacob Gopas

“…NF-kB was inhibited by PL-18 in two human cell-lines, L428 and A549, by preventing the nuclear translocation of p65 NF-kB. …”
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Analysis of the impact of the Covid-19 epidemic through the sojourn tax and the attitudes of the respondents by Jakovljević Nemanja

“…The impact of the global epidemic caused by the appearance and spread of the Covid19 virus has led to strong effects on all human labor activities, of which tourism stands out, as the activity most affected by the virus. …”
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Factors Associated with Methicillin Resistant Staphylococcus aureus Carriage by Masood Abdulkareem Abdulrahman, Arazoo Issa Taher

“…S. aureus is a common commensal of the skin and mucosal membranes of humans, with estimates of 20% (range from 12% to 30%) of healthy people are persistent  S.  …”
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Kidney Diseases Classification using Hybrid Transfer-Learning DenseNet201-Based and Random Forest Classifier by Abdalbasit Mohammed Qadir, Dana Faiq Abd

“…There are several disease kinds in global populations that may be related to human lifestyles, social, genetic, economic, and other factors related to the nature of the country they live in. …”
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Evaluation of Randomised Controlled Trials Published in Indian Specialty Dental Journals for Statistical Testing of Baseline Differences: A Meta-Epidemiological Study by Mahesh R. Khairnar, PG Naveen Kumar, Ananta Kusumakar, Zainab Akram, Harloveen Sabharwal, Sachin Jadhav

“…Objective: This study aimed to assess the proportion of RCTs on human participants comparing the baseline differences between intervention groups using the test of significance in nine dental specialty journals published in India and to estimate the proportion of studies reporting baseline demographic and clinical characteristics in a table. …”
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