Dimensions of suffering and the need for palliative care: experiences and expectations of patients living with cancer and diabetes and their caregivers in Mexico – a qualitative st... by Svetlana V Doubova, Ingrid Patricia Martinez-Vega, Felicia Knaul, Afsan Bhadelia, Diana Pérez-Moran, Nancy García-Cervantes

“…They expressed the importance of relief from suffering, viewing it as the health sector’s responsibility and requesting more humane, personalised care and access to medicines and pain clinics.Conclusions The multifaceted nature of SHS highlights the health system’s responsibility to provide high-quality palliative care. …”
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Host factor PLAC8 is required for pancreas infection by SARS-CoV-2 by Lesly Ibargüen-González, Sandra Heller, Darío López-García, Hanna Dietenberger, Thomas FE Barth, Patricia Gallego, Israel Fernández-Cadenas, Sayoa Alzate-Piñol, Catalina Crespí, Julieth A. Mena-Guerrero, Eugenia Cisneros-Barroso, Alejandro P. Ugalde, Gabriel Bretones, Charlotte Steenblock, Alexander Kleger, Marta L. DeDiego, Carles Barceló

“…We perform pseudovirus infection experiments in PLAC8 knock-out PDAC and human beta cell-derived cell lines and validate results with SARS-CoV-2 virus. …”
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Assessment of Microbiological Indoor Air Quality in Cattle Breeding Farms by Justyna Szulc, Małgorzata Okrasa, Katarzyna Dybka-Stępień, Michael Sulyok, Adriana Nowak, Anna Otlewska, Bogumiła Szponar, Katarzyna Majchrzycka

“…In addition, the cytotoxicity of the dust to the human epithelial lung cell line was determined by using the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay. …”
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High mortality rates and long-term complications in children with infectious brainstem encephalitis: A study of sixteen cases. by Yuanyuan Zhou, Yi Zhu, Lingfeng Cao, Yingyan Shi, Jun Shen

“…Among them, 31.3% (5/16) cases were diagnosed as human enterovirus infections, 12.5% (2/16) cases were confirmed to be influenza B virus infections, while one case each was diagnosed with herpes simplex virus 1 and human herpesvirus 6 infection. …”
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Unpacking the benefits of black soldier fly frass fertilizer towards nematode suppression and potato production by Emmanuel O. Anedo, Emmanuel O. Anedo, Emmanuel O. Anedo, Dennis Beesigamukama, Benson Mochoge, Nicholas K. Korir, Solveig Haukeland, Solveig Haukeland, Xavier Cheseto, Moses Nyongesa, Patrick Pwaipwai, Sevgan Subramanian, Abdou Tenkouano, Betty Kibaara, Chrysantus M. Tanga

“…Mineral fertilizers and synthetic nematicides are costly and cause negative impacts on humans and the environment, while organic fertilizers are less effective for soil health and nematode management. …”
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Meta-analysis examining the association between low platelet monoamine oxidase levels and Zuckerman's sensation seeking scale in a sex dependent manner by Jordan Winfield, Ian A. Mendez, Gabriel A. Frietze

“…MAO levels can be measured in humans by collecting blood platelets. Low platelet MAO levels in healthy individuals are associated with personality differences, such as increases in sensation seeking. …”
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Photovoltaic Farm Production Forecasting: Modified Metaheuristic Optimized Long Short-Term Memory-Based Networks Approach by Aleksandar Stojkovic, Bosko Nikolic, Miodrag Zivkovic, Nebojsa Bacanin

“…The best produced models attained mean squared error (MSE) scores of only 0.007297 for Indian Plant 1, 0.007662 for Indian Plant 2, and 0.001812 for Institute Mihailo Pupin dataset, emphasizing considerable potential of the suggested approach for real-world applications. …”
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Analysis of tumor-infiltrating exhausted T cells highlights IL-6 and PD1 blockade as a combined immunotherapy strategy for non-small cell lung cancer by Lulu Zhang, Lulu Zhang, Xiyuan Guo, Xiyuan Guo, Xiaoke Sun, Jue Liao, Qin Liu, Yingchun Ye, Zhihui Yang, Ratchada Cressey, Qing He, Qing Yuan, Qing Yuan

“…Finally, we assessed the effects of combined blockade of PD1 and IL-6 on macrophage recruitment in a zebrafish macrophage model and CD8+ T cell function and tumor growth in PBMC humanized mouse model.ResultsThe expression of exhaustion markers on CD8+ T cells was found to be notably higher in both tumor and paraneoplastic tissues compared to peripheral blood. …”
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Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions. by Karen Campos-León, Jack Ferguson, Thomas Günther, C David Wood, Steven W Wingett, Selin Pekel, Christy S Varghese, Leanne S Jones, Joanne D Stockton, Csilla Várnai, Michelle J West, Andrew Beggs, Adam Grundhoff, Boris Noyvert, Sally Roberts, Joanna L Parish

“…Upon infection, human papillomavirus (HPV) manipulates host cell gene expression to create an environment that is supportive of a productive and persistent infection. …”
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Introducing 3D printed models of fractures in osteology learning improves clinical reasoning skills among first-year medical students: a pilot study by Abhishek Agarwal, Anne D Souza, B. Jyostna, Ashwija Shetty, Nandini Bhat

“…Abstract Background The human bone anatomy is commonly taught using normal adult bones. …”
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Effects of the Treatment Technology of Soybean on Volatile Flavor Compounds of Plant-based Compound Milk during Storage by Xue WANG, Youqiang YU, Xiaoyang ZHENG, Hongjiang MA, Shiwei LIU, Wenxin WANG, Fang ZHOU, Shenglin DUAN

“…The results of human and electronic senses showed that the milk, flower, fruit and cereal flavors of plant-based compound milk 1# and 2# gradually increased during storage, and the peculiar smell gradually weakened. …”
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The impact of temperature on the shear bond strength of conventional multi-step and self-adhesive orthodontic adhesive systems: an in-vitro study by Grėtė Kazlauskaitė, Rytis Vaitiekūnas, Kristina Lopatienė, Audrius Jutas, Benedikta Palesik, Dalia Smailienė

“…Methods A total of 112 extracted human molars were randomly divided into eight groups (n = 14) for bonding tubes with two orthodontic adhesive systems (Transbond XT and GC Ortho Connect) at different temperatures: refrigeration temperature (4 °C), room temperature (20 °C), human body temperature (37 °C), and high temperature (55 °C). …”
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The inaccurate citation of the “Universal Declaration of Animal Rights” (UDAR) in the scientific literature: a scoping review by Alexandre Azevedo, Martin Whiting, Manuel Magalhães-Sant’Ana

“…Abstract Background The Universal Declaration of Animal Rights (UDAR), adopted in 1977 by an international NGO inspired by the Universal Declaration of Human Rights and made public the following year, aimed to establish a universal code for human conduct toward animals. …”
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The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity. by Liam C Hunt, Michelle Curley, Kudzai Nyamkondiwa, Anna Stephan, Jianqin Jiao, Kanisha Kavdia, Vishwajeeth R Pagala, Junmin Peng, Fabio Demontis

“…Mechanistically, UBE2D/eff is necessary to maintain optimal proteasome function: UBE2D/eff knockdown reduces the proteolytic activity of the proteasome, and this is rescued by transgenic expression of human UBE2D2, an eff homolog. Likewise, human UBE2D2 partially rescues the lifespan and proteostasis deficits caused by muscle-specific effRNAi and re-establishes the physiological levels of effRNAi-regulated proteins. …”
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Sustainability of Paddy Rice Farming in the Conservation of Birds in Uganda Amidst a Growing Expansion of the Rice farming Industry. by Sarah, Nachuha, Twagiramaria, Fortunate

“…This study was guided by the anthropogenic impacts hypothesis which proposes that humans have modified the ‘natural’ biodiversity patterns such that diversity is generally depressed in areas with long history of human occupation or intensive activities. …”
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Komparasi Metode Klasifikasi untuk Deteksi Ekspresi Wajah Dengan Fitur Facial Landmark by Fitra A. Bachtiar, Muhammad Wafi

“… Human machine interaction, khususnya pada facial behavior mulai banyak diperhatikan untuk dapat digunakan sebagai salah satu cara untuk personalisasi pengguna. …”
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The Multifaceted Roles of Myrrha in the Treatment of Breast Cancer: Potential Therapeutic Targets and Promises by Anwar Shams MD, MSc, PhD, Abdullah Ahmed Alzahrani, Taghreed A Ayash MSc, PhD, Shadi Tamur MD, FRCPC, FAAP, Majed AL-Mourgi MD, FRCS, FCCP, FACS

“…Background: Breast cancer is a critical threat to human health, and effective targeted agents showing lower systemic toxicity are still lacking. …”
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Perancangan User Experience Portal Media Interaksi Komunitas Kampus dengan Pendekatan Social Media Platform by Asyora Dewi Prabandani, Herman Tolle, Retno Indah Rokhmawati

“…A type of interaction that humans do as social beings in various places and situations. …”
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ISSUES ON THE APPLICATION OF A QUALITY-RISK MANAGEMENT SYSTEM IN A HEALTHCARE SERVICES PROVIDER UNIT by CONSTANTIN MILITARU, LEONARDO VOINESCU

“…A quality medical service can be attained through a rigorous and effective management of the quality of medical care itself, and through increased quality of human resources and materials involved and ensuring health and reduce the risks of treatment/ care patients. …”
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Tropical Orb Weaver Spider, Eriophora ravilla (C. L. Koch) (Arachnida: Araneae: Araneidae) by Glavis B. Edwards

“…Bites of this species are not known to cause serious effects to humans. This document is EENY-291 (originally published as DPI Entomology Circular 286), one of a series of Featured Creatures from the Entomology and Nematology Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. …”
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