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    iProtDNA-SMOTE: Enhancing protein-DNA binding sites prediction through imbalanced graph neural networks. by Ruiyan Huang, Wangren Qiu, Xuan Xiao, Weizhong Lin

    Published 2025-01-01
    “…We propose a method called iProtDNA-SMOTE, which utilizes non-equilibrium graph neural networks along with pre-trained protein language models to predict DNA binding residues. This approach effectively addresses the class imbalance issue in predicting protein-DNA binding sites by leveraging unbalanced graph data, thus enhancing model's generalization and specificity. …”
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