A conserved fungal Knr4/Smi1 protein is crucial for maintaining cell wall stress tolerance and host plant pathogenesis. by Erika Kroll, Carlos Bayon, Jason Rudd, Victoria J Armer, Anjana Magaji-Umashankar, Ryan Ames, Martin Urban, Neil A Brown, Kim Hammond-Kosack

Get full text

Geology and mineralization of the Dongping supergiant alkalic-hosted Au-Te deposit (>100 t Au) in Northern Hebei Province, China: A review by Shi-min Zhen, Da-zhao Wang, Zhong-jian Zha, Hai-jun Bai, Jiang Wang

Get full text

Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response by Daniel A. Skelly, John P. Graham, Mingshan Cheng, Mayuko Furuta, Andrew Walter, Thomas A. Stoklasek, Hongyuan Yang, Timothy M. Stearns, Olivier Poirion, Ji-Gang Zhang, Jessica D.S. Grassmann, Diane Luo, William F. Flynn, Elise T. Courtois, Chih-Hao Chang, David V. Serreze, Francesca Menghi, Laura G. Reinholdt, Edison T. Liu

“…The differentially expressed genes within these QTLs that define responder genetics are highly enriched for processes involving antigen processing and presentation, allograft rejection, and graft vs. host disease (all p < 1 × 10−10). …”
Get full text

Framework for Mapping Sublimation Features on Mars’ South Polar Cap Using Object-Based Image Analysis by Racine D. Cleveland, Vincent F. Chevrier, Jason A. Tullis

“…Mars’ south polar cap hosts dynamic landforms known as Swiss cheese features (SCFs), which form through the sublimation of carbon dioxide (CO₂) ice driven by the planet’s extreme seasonal and diurnal solar insolation cycles. …”
Get full text

High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion. by Claudia Cattoglio, Giulietta Maruggi, Cynthia Bartholomae, Nirav Malani, Danilo Pellin, Fabienne Cocchiarella, Zulma Magnani, Fabio Ciceri, Alessandro Ambrosi, Christof von Kalle, Frederic D Bushman, Chiara Bonini, Manfred Schmidt, Fulvio Mavilio, Alessandra Recchia

“…Analysis of integration sites in T cells obtained ex vivo two months after infusion showed no evidence of integration-related clonal expansion or dominance, but rather loss of cells harboring integration events interfering with RNA post-transcriptional processing. The study shows that high-definition maps of retroviral integration sites are a powerful tool to analyze the fate of genetically modified T cells in patients and the biological consequences of retroviral transduction.…”
Get full text

Remote Sensing of Alpine Peatlands: Challenges of Mapping Thousands of Sparse Small Sites Scattered Across Extensive Mountainous Territories by Qiqi Li, Manudeo Singh, Sonia Silvestri

“…However, they are globally understudied, including those in the Italian Alps, which host thousands of small sites averaging under 1 ha. …”
Get full text

Unveiling Physical Conditions and Star Formation Processes in the G47 Filamentary Cloud by O. R. Jadhav, L. K. Dewangan, A. Haj Ismail, N. K. Bhadari, A. K. Maity, Ram Kesh Yadav, Moustafa Salouci, Patricio Sanhueza, Saurabh Sharma

Get full text

Morphed and moving: TNFα-driven motility promotes cell dissemination through MAP4K4-induced cytoskeleton remodeling by Min Ma, Martin Baumgartner

“…We found that parasite infection promotes the production of the inflammatory cytokine TNFα in the host macrophage. We demonstrated that increased TNFα triggers motile and invasive properties by enhancing actin cytoskeleton remodeling and cell motility through the ser/thr kinase MAP4K4. …”
Get full text

Study of signal transduction factors involved in mycoparasitic response of Trichoderma atroviride by Scala V, Zeilinger S, Ambrosino P, Brunner K, Reithner B, Mach R L, Woo S L, Cristilli M, Scala F, Lorito M

“…In particular, it has been suggested that tga3 regulates the expression of chitinase-encoding genes, the secretion of the corresponding enzymes and the process of conidiation. Comparative proteome analysis of wild type and disruptants supported this hypothesis, and indicated many changes in the protein profiles of T. atroviride in different interaction conditions with plants and pathogenic hosts.…”
Get full text

Some Integral Type Fixed Point Theorems for Non-Self-Mappings Satisfying Generalized (ψ,φ)-Weak Contractive Conditions in Symmetric Spaces by Marwan Amin Kutbi, Mohammad Imdad, Sunny Chauhan, Wutiphol Sintunavarat

“…In the process, we also derive a fixed point theorem for four finite families of mappings which can be utilized to derive common fixed point theorems involving any number of finite mappings.…”
Get full text

The PA-X host shutoff site 100 V exerts a contrary effect on viral fitness of the highly pathogenic H7N9 influenza A virus in mice and chickens by Xia Chen, Ming Kong, Chunxi Ma, Manyu Zhang, Zenglei Hu, Min Gu, Xiaoquan Wang, Ruyi Gao, Shunlin Hu, Yu Chen, Xiaowen Liu, Daxin Peng, Xiufan Liu, Jiao Hu

“…Several viruses, including influenza A virus (IAV), encode viral factors to hijack cellular RNA biogenesis processes to direct the degradation of host mRNAs, termed “host shutoff.” …”
Get full text

Mapping recent timber harvest activity in a temperate forest using single date airborne LiDAR surveys and machine learning: lessons for conservation planning by G. Burch Fisher, Andrew J. Elmore, Matthew C. Fitzpatrick, Darin J. McNeil, Jeff W. Atkins, Jeffery L. Larkin

“…Future efforts that refine the model’s ability to better distinguish between more complex harvest classes and natural processes would be valuable.…”
Get full text

The Intermediate-mass Black Hole Reverberation Mapping Project: First Detection of Mid-infrared Lags in Prototypical Intermediate-mass Black Holes in NGC 4395 and POX 52 by Jingbo Sun, Hengxiao Guo, Wenwen Zuo, Paulina Lira, Minfeng Gu, Philip G. Edwards, Shu Wang, Jamie Stevens, Tao An, Samuzal Barua, Zhen-yi Cai, Haicheng Feng, Alok C. Gupta, Luis C. Ho, Dragana Ilić, Andjelka B. Kovačević, ShaSha Li, Mar Mezcua, Luka Č. Popović, Paula Sánchez-Sáez, Mouyuan Sun, Rongfeng Shen, Vivian U, Oliver Vince, Junxian Wang, Xuebing Wu, Zhefu Yu, Zhenya Zheng

Get full text

Interactive Visualization for the GTFS and GTFS-RT Data of Budapest by Róbert Tóth, Márton Ispány, Marianna Zichar

“…In this paper, we present our dataset that was built by retrieving and pre-processing the data sources of the open data platform of BKK Futár, hosted by the Centre for Budapest Transport Company (BKK). …”
Get full text

Transcriptomic profiles of Crandell-Rees feline kidney cells infected with Varicellovirus felidalpha-1 (FHV-1) field and vaccine strains by Emily Kwan, Alistair R. Legione, Carol A. Hartley, Joanne M. Devlin

“…The transcriptomes were characterised using RNA-sequencing. To determine the host cellular transcription profile, the total transcripts were mapped to the cat genome and compared to uninfected cells. …”
Get full text

Sentiment Analysis of Social Networking Data Using Categorized Dictionary by Akansha Singh, Aastha Sharma, Krishna Singh, Anuradha Dhull

Get full text

Geohazard features of the Eastern Sardinia by Fabiano Gamberi, Michael Marani, Giacomo Dalla Valle, Marzia Rovere, Elisa Leidi, Alessandra Mercorella, Valentina Ferrante

“…The MaGIC project (Marine Geohazard along the Italian Coasts) had the aim of mapping the geohazard in the Italian seas and resulted in numerous maps. …”
Get full text

Visualizing Tomato Spotted Wilt Virus Protein Localization: Cross-Kingdom Comparisons of Protein-Protein Interactions by K. M. Martin, Y. Chen, M. A. Mayfield, M. Montero-Astúa, A. E. Whitfield

Get full text

A computational framework for processing time-series of earth observation data based on discrete convolution: global-scale historical Landsat cloud-free aggregates at 30 m spatial... by Davide Consoli, Leandro Parente, Rolf Simoes, Murat Şahin, Xuemeng Tian, Martijn Witjes, Lindsey Sloat, Tomislav Hengl

“…Processing large collections of earth observation (EO) time-series, often petabyte-sized, such as NASA’s Landsat and ESA’s Sentinel missions, can be computationally prohibitive and costly. …”
Get full text

Deposits and occurrences of turquoise and variscite in the Republic of Tajikistan by A. K. Litvinenko, Sh. T. Vosihov

“…For the first time, the study introduced a geological summary of all known deposits and occurrences of turquoise and variscite in the territory of the Republic of Tajikistan and a tectonic map of their location. A new, hydrothermal-metasomatic formation mechanism is proposed, whereinthe substances for turquoise and variscite (copper, aluminum, and phosphorus) were sourced from host volcanic and siliceous rocks through a lateral-secretion process.   …”
Get full text