Genomic adaptation of Clostridium perfringens to human intestine by Ke Wu, Juan Wang, Zelin Yan, Yanyan Zhu, Shaolin Wang, Bo Fu, Chengtao Sun, Ruichao Li, Edward M. Fox, Séamus Fanning, Li Bai, Yang Wang, Yizhi Tang, Zhe Yin, Rong Zhang, Hongning Wang

“…Moreover, we observed that the genomic characteristics of C. perfringens correlate with host species, with specific toxin genes, such as pfoA and colA, potentially influencing host selectivity. …”
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Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response by Daniel A. Skelly, John P. Graham, Mingshan Cheng, Mayuko Furuta, Andrew Walter, Thomas A. Stoklasek, Hongyuan Yang, Timothy M. Stearns, Olivier Poirion, Ji-Gang Zhang, Jessica D.S. Grassmann, Diane Luo, William F. Flynn, Elise T. Courtois, Chih-Hao Chang, David V. Serreze, Francesca Menghi, Laura G. Reinholdt, Edison T. Liu

“…The differentially expressed genes within these QTLs that define responder genetics are highly enriched for processes involving antigen processing and presentation, allograft rejection, and graft vs. host disease (all p < 1 × 10−10). …”
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Framework for Mapping Sublimation Features on Mars’ South Polar Cap Using Object-Based Image Analysis by Racine D. Cleveland, Vincent F. Chevrier, Jason A. Tullis

“…Mars’ south polar cap hosts dynamic landforms known as Swiss cheese features (SCFs), which form through the sublimation of carbon dioxide (CO₂) ice driven by the planet’s extreme seasonal and diurnal solar insolation cycles. …”
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High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion. by Claudia Cattoglio, Giulietta Maruggi, Cynthia Bartholomae, Nirav Malani, Danilo Pellin, Fabienne Cocchiarella, Zulma Magnani, Fabio Ciceri, Alessandro Ambrosi, Christof von Kalle, Frederic D Bushman, Chiara Bonini, Manfred Schmidt, Fulvio Mavilio, Alessandra Recchia

“…Analysis of integration sites in T cells obtained ex vivo two months after infusion showed no evidence of integration-related clonal expansion or dominance, but rather loss of cells harboring integration events interfering with RNA post-transcriptional processing. The study shows that high-definition maps of retroviral integration sites are a powerful tool to analyze the fate of genetically modified T cells in patients and the biological consequences of retroviral transduction.…”
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RNA Interference in Fungal Plant Pathogens: What Do We Know from <i>Botrytis cinerea</i> with Research Hotspots and Gaps, and What Are the Future Directions? by Guy Smagghe

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WIde Separation Planets In Time (WISPIT): A Gap-clearing Planet in a Multi-ringed Disk around the Young Solar-type Star WISPIT 2 by Richelle F. van Capelleveen, Christian Ginski, Matthew A. Kenworthy, Jake Byrne, Chloe Lawlor, Dan McLachlan, Eric E. Mamajek, Tomas Stolker, Myriam Benisty, Alexander J. Bohn, Laird M. Close, Carsten Dominik, Sebastiaan Haffert, Rico Landman, Jie Ma, Ignas Snellen, Ryo Tazaki, Nienke van der Marel, Lukas Welzel, Yapeng Zhang

“…We directly detect a young protoplanet, WISPIT 2b, embedded in a disk gap and show that it is comoving with its host star. …”
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Remote Sensing of Alpine Peatlands: Challenges of Mapping Thousands of Sparse Small Sites Scattered Across Extensive Mountainous Territories by Qiqi Li, Manudeo Singh, Sonia Silvestri

“…The method identified 11.635 km2 of alpine peatlands, surpassing the 7.764 km2 documented in official inventories, this discrepancy may be due to overestimation but also gaps in the existing reference inventory. In the classification process, DEM derived variables proved more effective than optical and microwave derived variables. …”
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Behavioral and Morphological Adaptations of Tortoise Tick Hyalomma aegyptium to Testudo graeca: Evidence for Complex Evolutionary History by Sirri Kar, Baris Donmez, Bugrahan Regaip Kilinc, Zafer Sakaci, Sengul Talay, Dennis Bente, Agustin Estrada‐Peña

“…All these traits seem evolutionarily driven to shield the tick from environmental and feeding‐related challenges while minimizing the infestation's life‐threatening pressure on the host. Although these remarkable adaptation characteristics suggest a deep‐rooted coevolutionary background, some critical discrepancies in the fundamentals of host–parasite interactions make it more plausible that the primary speciation process of H. aegyptium had already occurred in an extinct giant tortoise species before its adaptation to the genus Testudo.…”
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Cancers missed, women dismissed yet persist: natural language processing of online forums by Kathleene T. Ulanday, Maxim Topaz, Jeanette Shekelle, Marley Gibbons, Desiree Walker, Paula M. Castaño, Amanda Nixon, Stacy Lewis, Mary Beth Terry, Lauren C. Houghton

“…Abstract Objective To identify gaps and delays in the detection of early onset cancer. …”
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A three-way transcriptomic crosstalk interaction in a biocontrol agent (Bacillus velezensis), a fungal pathogen (Colletotrichum gloeosporioides), and a walnut host (Juglans regia L... by Shiwei Wang, Hanmingyue Zhu, Shuying Li, Tianhui Zhu

“…This study addresses knowledge gaps in the biocontrol-pathogen-host interaction and provides a theoretical foundation for developing environmentally sustainable strategies to control walnut anthracnose.…”
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Estimating contact process saturation in sylvatic transmission of Trypanosoma cruzi in the United States. by Christopher Kribs-Zaleta

“…Results are used to draw conclusions about saturation and which population density drives each of the two contact-based infection processes (stercorarian/bloodborne and oral). Analysis suggests that the vector feeding process associated with stercorarian transmission to hosts and bloodborne transmission to vectors is limited by the population density of vectors when dealing with woodrats, but by that of hosts when dealing with raccoons and opossums, while the predation of hosts on vectors which drives oral transmission to hosts is limited by the population density of hosts. …”
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Postlarval Shrimp-Associated Microbiota and Underlying Ecological Processes over AHPND Progression by Zhongjiang Zhou, Jiaqi Lu, Pingping Zhan, Jinbo Xiong

“…To address this knowledge gap, a comparative analysis of postlarvae-associated microbiota and the ecological processes underlying AHPND progression was performed by sequencing the bacterial V3–V4 hypervariable region of the 16S rRNA gene. …”
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Unveiling Physical Conditions and Star Formation Processes in the G47 Filamentary Cloud by O. R. Jadhav, L. K. Dewangan, A. Haj Ismail, N. K. Bhadari, A. K. Maity, Ram Kesh Yadav, Moustafa Salouci, Patricio Sanhueza, Saurabh Sharma

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Morphed and moving: TNFα-driven motility promotes cell dissemination through MAP4K4-induced cytoskeleton remodeling by Min Ma, Martin Baumgartner

“…We found that parasite infection promotes the production of the inflammatory cytokine TNFα in the host macrophage. We demonstrated that increased TNFα triggers motile and invasive properties by enhancing actin cytoskeleton remodeling and cell motility through the ser/thr kinase MAP4K4. …”
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Study of signal transduction factors involved in mycoparasitic response of Trichoderma atroviride by Scala V, Zeilinger S, Ambrosino P, Brunner K, Reithner B, Mach R L, Woo S L, Cristilli M, Scala F, Lorito M

“…In particular, it has been suggested that tga3 regulates the expression of chitinase-encoding genes, the secretion of the corresponding enzymes and the process of conidiation. Comparative proteome analysis of wild type and disruptants supported this hypothesis, and indicated many changes in the protein profiles of T. atroviride in different interaction conditions with plants and pathogenic hosts.…”
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Beyond Asexual: Genomics-Driven Progress in Unveiling Sexual Reproduction in Cereal Rust Fungi by Shideh Mojerlou, Mareike Moeller, Benjamin Schwessinger, Julian Rodriguez-Algaba

“…Integrating multiple omics approaches with advanced cell biology techniques can help address these knowledge gaps, particularly in understanding sexual reproduction and its role in pathogen evolution. …”
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Unveiling the ecological processes driving soil and lichen microbiome assembly along an urbanization gradient by Panji Cahya Mawarda, Rens van der Kaaij, Francisco Dini-Andreote, Deniz Duijker, Michael Stech, Adrianus GCL Speksnijder

“…Yet, research on the urbanization impact on environmental and host-associated microbiomes, particularly on the ecological processes that mediate their assembly and function, remains scarce. …”
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Some Integral Type Fixed Point Theorems for Non-Self-Mappings Satisfying Generalized (ψ,φ)-Weak Contractive Conditions in Symmetric Spaces by Marwan Amin Kutbi, Mohammad Imdad, Sunny Chauhan, Wutiphol Sintunavarat

“…In the process, we also derive a fixed point theorem for four finite families of mappings which can be utilized to derive common fixed point theorems involving any number of finite mappings.…”
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Enhancement Optical Characterized of Tin Oxide in Polymer Polyvinyl alcohol Colloid Prepared by Laser Ablation Method by Nadheer Jassim Mohammed, Zahraa Sabah Rasheed

“…Components with novel structures and better efficiency compared to conventionally processed components are required for technological advances. …”
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The PA-X host shutoff site 100 V exerts a contrary effect on viral fitness of the highly pathogenic H7N9 influenza A virus in mice and chickens by Xia Chen, Ming Kong, Chunxi Ma, Manyu Zhang, Zenglei Hu, Min Gu, Xiaoquan Wang, Ruyi Gao, Shunlin Hu, Yu Chen, Xiaowen Liu, Daxin Peng, Xiufan Liu, Jiao Hu

“…Several viruses, including influenza A virus (IAV), encode viral factors to hijack cellular RNA biogenesis processes to direct the degradation of host mRNAs, termed “host shutoff.” …”
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