Baicalin attenuates LPS-induced periodontal inflammation response by inhibiting autophagy by Yifan Cheng, Ming Jiang, Xu Qin, Jing Mao, Yan Liu, Guangxun Zhu

“…This condition This condition results from the intricate interaction between bacterial infections and the host’s inflammatory responses, driving disease progression. …”
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Computational tools and data integration to accelerate vaccine development: challenges, opportunities, and future directions by Lindsey N. Anderson, Charles Tapley Hoyt, Jeremy D. Zucker, Andrew D. McNaughton, Jeremy R. Teuton, Klas Karis, Natasha N. Arokium-Christian, Jackson T. Warley, Zachary R. Stromberg, Benjamin M. Gyori, Benjamin M. Gyori, Neeraj Kumar

“…Despite significant advances in the field of vaccine development there remain numerous challenges including the lack of standardized data reporting and curation practices, making it difficult to determine correlates of protection from experimental and clinical studies. Significant gaps in data and knowledge integration can hinder vaccine development which relies on a comprehensive understanding of the interplay between pathogens and the host immune system. …”
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The diversity, dynamics, and culturability of bacterial and fungal communities present in warm-season pasture grass seeds by Rens R. T. van Essen, Rens R. T. van Essen, Jatinder Kaur, Jatinder Kaur, Tongda Li, Tongda Li, Ross C. Mann, Tim I. Sawbridge, Tim I. Sawbridge

“…This has resulted in an increasing importance of warm-season pasture grasses to fill the feed gaps left by the affected temperate grasses. In this study, we assessed the microbial communities present in commercially available warm-season pasture grass seeds. …”
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Virocell resource manipulation under nutrient limitation by Morgan M. Lindback, Cristina Howard-Varona, Jane Fudyma, Malak Tfaily, Matthew B. Sullivan, Melissa B. Duhaime

“…ABSTRACT Virus-infected cells, called virocells, impact host metabolic functions, resources, and ecosystem processes, but the effects of nutrient limitation remain less well understood. …”
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Racial inequality in the production of fresh vegetables and cut flowers in Argentina: an analysis in Greater La Plata by Nuria Caimmi

“…Positive valuations of ultra-processed foods by those living and working in the area reflect the importance of belonging to the host society, running parallel to strategies for preserving food preparations from before migration. …”
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Alteration of mitochondrial function in arthropods during arboviruses infection: a review of the literature by María E. Santana-Román, Santos Ramírez-Carreto, Paola Maycotte, Victoria Pando-Robles

“…Some arboviruses can replicate within arthropod vectors without harming the host. Successful transmission depends on efficient viral replication in the vector’s tissues, ultimately reaching the salivary glands for transmission to a vertebrate host, including humans, via blood-feeding. …”
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Analysis of Streptococcus dysgalactiae subspecies equisimilis gene transcripts during experimental primate necrotizing myositis by Jesus M. Eraso, Randall J. Olsen, S. Wesley Long, Ahmad Faili, Samer Kayal, James M. Musser

“…However, the molecular processes underlying these infections remain poorly understood. …”
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Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus. by Tobias Dietsche, Mehari Tesfazgi Mebrhatu, Matthias J Brunner, Patrizia Abrusci, Jun Yan, Mirita Franz-Wachtel, Charlotta Schärfe, Susann Zilkenat, Iwan Grin, Jorge E Galán, Oliver Kohlbacher, Susan Lea, Boris Macek, Thomas C Marlovits, Carol V Robinson, Samuel Wagner

“…However, the in vivo placement of these components in the needle complex and their function during the secretion process remained poorly defined. Here we present evidence that a SpaP pentamer forms a 15 Å wide pore and provide a detailed map of SpaP interactions with the export apparatus components SpaQ, SpaR, and SpaS. …”
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Integrative transcriptomic and proteomic analyses reveal that carbon metabolism and complement system of Madin Darby Bovine Kidney cells are affected by bovine coronavirus infectio... by Hui Zhang, Qisheng Yu, Rui Guo, Qing Zhu, Jin Yu, Zhaohui Zhang, Lan Lan, Cheng Tang, Changqing Yu, Bin Zhang

“…It revealed a regulatory network for analyzing the mechanisms of BCoV-host interactions and provides valuable insights into the pathogenesis of BCoV.…”
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Glucocorticoid therapy for sepsis in the AI era: a survey on current and future approaches by Chenglong Liang, Shuo Pan, Wei Wu, Fanxuan Chen, Chengxi Zhang, Chen Zhou, Yifan Gao, Xiangyuan Ruan, Shichao Quan, Qi Zhao, Jingye Pan

“…The integration of AI in sepsis treatment has the potential to address existing gaps in knowledge, especially in the application of corticosteroids. …”
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Stress generation, relaxation and size control in confined tumor growth. by Huaming Yan, Daniel Ramirez-Guerrero, John Lowengrub, Min Wu

“…Our study provides insight on how the biophysical properties of the tumor and host microenvironment, mechanical feedback control and diffusion-limited differential growth act in concert to regulate spatial patterns of stress and growth. …”
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Unveiling the power of high-dimensional cytometry data with cyCONDOR by Charlotte Kröger, Sophie Müller, Jacqueline Leidner, Theresa Kröber, Stefanie Warnat-Herresthal, Jannis Bastian Spintge, Timo Zajac, Anna Neubauer, Aleksej Frolov, Caterina Carraro, DELCODE Study Group, Frank Jessen, Simone Puccio, Anna C. Aschenbrenner, Joachim L. Schultze, Tal Pecht, Marc D. Beyer, Lorenzo Bonaguro

“…While several analytical platforms and bioinformatics tools have become available for the analysis of HDC data, these are either web-hosted with limited scalability or designed for expert computational biologists, making their use unapproachable for wet lab scientists. …”
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Exploring the Dynamics of an Arctic Sea Ice Melt Event Using a Coupled Atmosphere‐Ocean Single‐Column Model (AOSCM) by Kerstin Hartung, Gunilla Svensson, Jareth Holt, Anna Lewinschal, Michael Tjernström

“…Abstract The Arctic climate system is host to many processes which interact vertically over the tightly coupled atmosphere, sea ice and ocean. …”
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Tpc1 is an important Zn(II)2Cys6 transcriptional regulator required for polarized growth and virulence in the rice blast fungus. by Rita Galhano, Adriana Illana, Lauren S Ryder, Julio Rodríguez-Romero, Marie Demuez, Muhammad Badaruddin, Ana Lilia Martinez-Rocha, Darren M Soanes, David J Studholme, Nicholas J Talbot, Ane Sesma

“…The establishment of polarity is a critical process in pathogenic fungi, mediating infection-related morphogenesis and host tissue invasion. …”
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Evaluation of Microbial Transplantation from High-Productivity Soil to Improve Soybean Performance in Less Productive Farmland by Danilo Tosta Souza, Aurélio Carneiro Soares Moreira, Hélio Danilo Quevedo, André May

“…Future research should optimize (a) inoculant composition for specific productivity gaps; (b) delivery systems; and (c) compatibility with resident microbiomes, particularly in systems where niche-specific processes govern microbial establishment.…”
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Dietary transformations and health implications in migrant populations: a global perspective by Joseph Vinod Varre, Mia Dustin, Stephan Van Vliet

“…BackgroundDietary acculturation—the process by which migrants adopt the dietary patterns of their host country—has become increasingly relevant given the unprecedented scale of international migration. …”
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Cell wall remodeling in a fungal pathogen is required for hyphal growth into microspaces by Hinata Miki, Melani Mariscal Gomez, Ayaka Itani, Daisuke Yamanaka, Yoshikatsu Sato, Antonio Di Pietro, Norio Takeshita

“…The ability of fungal hyphae to traverse narrow plant tissue spaces, such as apoplastic gaps and plasmodesmata, is essential for successful host colonization. …”
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The small RNA complement of adult Schistosoma haematobium. by Andreas J Stroehlein, Neil D Young, Pasi K Korhonen, Ross S Hall, Aaron R Jex, Bonnie L Webster, David Rollinson, Paul J Brindley, Robin B Gasser

“…The present work should facilitate the future curation and experimental validation of sncRNA functions in schistosomes to enhance our understanding of post-transcriptional gene regulation and of the roles that sncRNAs play in schistosome reproduction, development and parasite-host cross-talk.…”
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CD81 is a receptor for equine arteritis virus (family: Arteriviridae) by Sara M. Maloney, Teressa M. Shaw, Kylie M. Nennig, Malorie S. Larsen, Aadit Shah, Ashish Kumar, Joseph Marcotrigiano, Joe Grove, Eric J. Snijder, Robert N. Kirchdoerfer, Adam L. Bailey

“…Bypassing the entry step of the viral life cycle by transfecting the EAV genome into CD81-knockout cells produced infectious EAV, implicating CD81 in the EAV entry process. Screening of CD81 orthologs from natural arterivirus hosts identified the brushtail possum CD81 as unsupportive of EAV entry, indicating that CD81 incompatibility can serve as a barrier to cross-species infection. …”
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Multipurpose watermarking realizing image copyright notification,copyright protection and content authentication by ZHU Cong-xu

“…A multipurpose image watermarking scheme based on chaotic systems and sub-image lifting wavelet transformation（LWT） was proposed.Firstly, the host image was divided into 8×8 sub-images and each sub-image was performed 2-level LWT.Then, the invisible watermarks for copyright protection and content authentication were respectively embedded into low and intermediate frequency LWT components of some sub-images that were randomly selected by general Arnold map.A new kind of quantization technique was adopted in the embedding process and the extracting process was blind.Secondly, the visible watermarks for copyright notification were embedded into the image spatial domain based on image fusion method, in which the embedding coefficients were generated by the 4D hyperchaotic sequences.Experimental results were presented, showing that the proposed watermarking scheme is effective.…”
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