Balancing harm and harmony: Evolutionary dynamics between gut microbiota-derived flagellin and TLR5-mediated host immunity and metabolism by Boram Seo, Mi Young Lim

“…The gut microbiota maintains host health and shapes immune responses through intricate host-microbe interactions. …”
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Multi-omics integration reveals functional signatures of gut microbiome in atherosclerosis by Hongbo Shi, Meitao Wu, Xiaoliang Wu, Zhuoxin Liu, Shuo Jiang, Gen Li, Yetong Yang, Yanghe Fu, Qiuping Wang, Guangde Zhang, Liang Cheng

“…While the associations between microbial imbalance and AS pathogenesis are well-documented, the pathophysiological mechanisms governing microbe-host crosstalk remain incompletely characterized. …”
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Advances in intestinal epithelium and gut microbiota interaction by Sen Yang, Sen Yang, Hanmin Liu, Hanmin Liu, Hanmin Liu, Hanmin Liu, Yang Liu, Yang Liu, Yang Liu, Yang Liu

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Integrated Transcriptome and Microbiome Analyses Reveal Growth- and Stress-Response-Related Genes and Microbes in Mandarin Fish (<i>Siniperca chuatsi</i>) by Fan Zhou, Wei Liu, Ming Qi, Qianrong Liang, Gaohua Yao, Cheng Ma, Xueyan Ding, Zaihang Yu, Xinyu Li, Zhanqi Wang

“…These findings suggest that enhanced immune homeostasis and metabolic flexibility in group T may result from coordinated host gene expression and <i>Lactobacillus</i>-driven microbiome modulation. …”
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MicroGlycoDB: A database of microbial glycans using Semantic Web technologies by Sunmyoung Lee, Louis-David Leclercq, Yann Guerardel, Christine M. Szymanski, Thomas Hurtaux, Tamara L. Doering, Takane Katayama, Kiyotaka Fujita, Kazuhiro Aoki, Kiyoko F. Aoki-Kinoshita

“…Glycoconjugates are present on microbial surfaces and play critical roles in modulating interactions with the environment and the host. Extensive research on microbial glycans, including elucidating the structural diversity of the glycan moieties of glycoconjugates and polysaccharides, has been carried out to investigate the function of glycans in modulating the interactions between the host and microbes, to explore their potential applications in the therapeutic targeting of pathogenic species, and in the use as probiotics in gut microbiomes. …”
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Integrated multi-omics reveals the relationship between growth performance, rumen microbes and metabolic status of Hu sheep with different residual feed intakes by Yanzhen Zhang, Xiaowei Zhang, Dingren Cao, Jinyong Yang, Huiling Mao, Lingling Sun, Chong Wang

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Integrating genome‐ and transcriptome‐wide association studies to uncover the host–microbiome interactions in bovine rumen methanogenesis by Wei Wang, Zhenyu Wei, Zhuohui Li, Jianrong Ren, Yanliang Song, Jingyi Xu, Anguo Liu, Xinmei Li, Manman Li, Huimei Fan, Liangliang Jin, Zhannur Niyazbekova, Wen Wang, Yuanpeng Gao, Yu Jiang, Junhu Yao, Fuyong Li, Shengru Wu, Yu Wang

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An in vitro model demonstrating homeostatic interactions between reconstructed human gingiva and a saliva-derived multispecies biofilm by Lin Shang, Sanne Roffel, Vera Slomka, Eleanor M. D’Agostino, Aline Metris, Mark J. Buijs, Bernd W. Brandt, Dongmei Deng, Susan Gibbs, Bastiaan P. Krom

“…Abstract Background In the oral cavity, host-microbe interactions (HMI) continuously occur and greatly impact oral health. …”
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A three-way transcriptomic crosstalk interaction in a biocontrol agent (Bacillus velezensis), a fungal pathogen (Colletotrichum gloeosporioides), and a walnut host (Juglans regia L... by Shiwei Wang, Hanmingyue Zhu, Shuying Li, Tianhui Zhu

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Endophytic fungi—Big player in plant-microbe symbiosis by Qian-xi Li, Fu-cheng Lin, Zhen-zhu Su

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Integrated multi-omics to elucidate the interplay between rumen microorganisms and host metabolism in Hu sheep supplemented with herbal preparations by Chunhui Wang, Qiao Li, Xingcai Qi, Huihui Wang, Yi Wu, Keyan Ma, Juanjuan Song, Zilong Liu, Youji Ma

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Deciphering the coordinated roles of the host genome, duodenal mucosal genes, and microbiota in regulating complex traits in chickens by Fangren Lan, Xiqiong Wang, Qianqian Zhou, Xiaochang Li, Jiaming Jin, Wenxin Zhang, Chaoliang Wen, Guiqin Wu, Guangqi Li, Yiyuan Yan, Ning Yang, Congjiao Sun

“…Results Here, we investigated this complex interplay in a sizable population of 705 hens, employing integrative analyses to examine the relationships among the host genome, mucosal gene expression, and gut microbiota. …”
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Unlocking the potential of engineered microbes in immunotoxin-based cancer therapy by Quan Wang, Quan Wang, Rui Cao, Yuxing Xie, Zhuoyi Zhang, Xianguo Li, Yan Zhang, Haolin Luo, Hui Yao, Ping Xue, Shuai Ni

“…., yeast, microalgae) to colonize tumors and act as efficient hosts for IT production. By integrating ITs into these microbes and employing precise circuits (e.g., phage lysis systems, signal peptide fusions), controlled secretion of recombinant immunotoxins (RITs) can be achieved. …”
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Deep learning enabled integration of tumor microenvironment microbial profiles and host gene expressions for interpretable survival subtyping in diverse types of cancers by Haohong Zhang, Xinghao Xiong, Mingyue Cheng, Lei Ji, Kang Ning

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Circadian rhythms of gut microbiota and plaque vulnerability: mechanisms and chrono-microbiota modulation interventions by Taiyu Zhai, Xueyang Zou, Zichen Zhang, Yifei Wang, Lin Shi, Wenbo Ren, Jing Huang

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Detection and In Vivo Validation of <i>Dichorhavirus</i> e-Probes in Meta-Transcriptomic Data via Microbe Finder (MiFi^®) Discovers a Novel Host and a Possible New Strain... by Avijit Roy, Jonathan Shao, Andres S. Espindola, Daniel Ramos Lopez, Gabriel Otero-Colina, Yazmín Rivera, Vessela A. Mavrodieva, Mark K. Nakhla, William L. Schneider, Kitty Cardwell

“…The E-probe Diagnostic for Nucleic Acid Analysis (EDNA) was developed to reduce computational effort and then integrated within Microbe-Finder (MiFi^®) online platform to design and evaluate e-probes in raw High Throughput Sequencing (HTS) data. …”
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Extracellular vesicle miRNAs promote the intestinal microenvironment by interacting with microbes in colitis by Qichen Shen, Zhuizui Huang, Lingyan Ma, Jiachen Yao, Ting Luo, Yao Zhao, Yingping Xiao, Yuanxiang Jin

“…However, the roles of EVs-miRNAs and MVs in host-microbe interactions in colitis remain unclear. …”
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The power of microbes: the key role of gut microbiota in the initiation and progression of colorectal cancer by Bo Han, Yongfeng Zhang, Xue Feng, Jun Yang, Baolin Wang, Jiang Fang, Zhigang Wang, Jun Zhu, Ge Niu, Youxiang Guo

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Enhanced metagenomic strategies for elucidating the complexities of gut microbiota: a review by Xinru Li, Haiyan Lu

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Studies on the concerted interaction of microbes in the gastrointestinal tract of ruminants on lignocellulose and its degradation mechanism by Runqi Fu, Runqi Fu, Lin Han, Lin Han, Qian Li, Qian Li, Zhe Li, Yue Dai, Jing Leng, Jing Leng

“…In the future, by revealing the mechanism of microbe-host synergy and integrating multi-omics technologies, the study of ruminant gastrointestinal microbial ecosystems will provide new solutions to promote the efficient utilization of lignocellulose and alleviate the global energy crisis.…”
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