Optimisation of the deployment of automated external defibrillators in public places in England by Terry P Brown, Lazaros Andronis, Asmaa El-Banna, Benjamin KH Leung, Theodoros Arvanitis, Charles Deakin, Aloysius N Siriwardena, John Long, Gareth Clegg, Steven Brooks, Timothy CY Chan, Steve Irving, Louise Walker, Craig Mortimer, Sandra Igbodo, Gavin D Perkins

“…Patient and public involvement The project was designed to ensure meaningful patient and public involvement (PPI) was embedded throughout the study. The PPI co-applicant was involved from the conception of the study and made valuable contribution to the development of the proposal, and reviewed and commented on work at various stages of the project. …”
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Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms: FUTURE, a superiority RCT and economic evaluation by Mohamed Abdel-Fattah, Christopher Chapple, Suzanne Breeman, David Cooper, Helen Bell-Gorrod, Preksha Kuppanda, Karen Guerrero, Simon Dixon, Nikki Cotterill, Karen Ward, Hashim Hashim, Ash Monga, Karen Brown, Marcus Drake, Andrew Gammie, Alyaa Mostafa, Rebecca Bruce, Victoria Bell, Christine Kennedy, Suzanne Evans, Graeme MacLennan, John Norrie

“…To estimate longer-term economic differences, a hybrid model with a decision tree describing short-term events and Markov processes describing long-term events was developed using external evidence that captures clinical and patient events beyond the end of the trial. …”
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Mapping the global distribution of lead and its isotopes in seawater with explainable machine learning by A. Olivelli, A. Olivelli, A. Olivelli, R. Arcucci, M. Rehkämper, T. van de Flierdt

“…In line with observations, our model outputs show that (i) the surface Indian Ocean has the highest levels of pollution, (ii) pollution from previous decades is sinking in the North Atlantic and Pacific oceans, and (iii) waters characterised by highly anthropogenic Pb isotope fingerprints are spreading from the Southern Ocean throughout the Southern Hemisphere at intermediate depths. …”
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Intersecting factors of disadvantage and discrimination and their effect on daily life during the coronavirus pandemic: the CICADA-ME mixed-methods study by Carol Rivas, Amanda P Moore, Alison Thomson, Kusha Anand, Zainab Zuzer Lal, Alison Fang-Wei Wu, Ozan Aksoy

“…Participant anxieties about contracting COVID-19 from people lax in infection containment measures pertained throughout but escalated when the country opened up in mid-2021. …”
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Medical Assistance in Dying for Persons Suffering Solely from Mental Illness in Canada by Chloe Eunice Panganiban, Srushhti Trivedi

“…In these countries, there are specific (although different) requirements for the process; overall, for mental illness, the illness must be verifiable and not simply related to a perception of satisfaction with the length of life. …”
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Collagenase injection versus limited fasciectomy surgery to treat Dupuytren’s contracture in adult patients in the UK: DISC, a non-inferiority RCT and economic evaluation by Joseph Dias, Puvan Tharmanathan, Catherine Arundel, Charlie Welch, Qi Wu, Paul Leighton, Maria Armaou, Belen Corbacho, Nick Johnson, Sophie James, John Cooke, Christopher Bainbridge, Michael Craigen, David Warwick, Samantha Brady, Lydia Flett, Judy Jones, Catherine Knowlson, Michelle Watson, Ada Keding, Catherine Hewitt, David Torgerson

“…Indeed, the observed data are highly compatible with LF being superior to collagenase with regard to the primary outcome measure at both these time points. …”
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