Progression of Ankle Osteoarthritis Is Associated with Distinct Synovial Phenotypes by Julia Matthias MD, Michael A. David PhD, Sara E. Buckley DO, Nathaniel Zona BA, Michael Zuscik PhD, Kenneth Hunt MD

“…Category: Ankle Arthritis; Basic Sciences/Biologics Introduction/Purpose: Despite the high incidence and socioeconomic burden of ankle osteoarthritis (OA), limited research has been undertaken to identify factors driving the ankle-specific disease process. …”
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Endothelial Plasticity: Shifting Phenotypes through Force Feedback by Guido Krenning, Valerio G. Barauna, José E. Krieger, Martin C. Harmsen, Jan-Renier A. J. Moonen

“…The endothelial lining of the vasculature is exposed to a large variety of biochemical and hemodynamic stimuli with different gradients throughout the vascular network. Adequate adaptation requires endothelial cells to be highly plastic, which is reflected by the remarkable heterogeneity of endothelial cells in tissues and organs. …”
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Layered Production Allocation Method for Dual-Gas Co-Production Wells by Guangai Wu, Zhun Li, Yanfeng Cao, Jifei Yu, Guoqing Han, Zhisheng Xing

“…Through a comparison of calculated and simulated results, the maximum relative error occurs during abrupt changes in the production capacity, approximately 6.37%, while for most time periods, the error remains within 1%, with an average error of 0.49% throughout the process. These results substantially improve the timeliness and accuracy of the reservoir identification. …”
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Insights from model plants to improve cotton’s use of nitrogen and phosphorus by Yuanchun Pu, Peilin Wang, Mubashir Abbas, Asif Iqbal, Qiang Dong, Tong Luo, Qianqian Wang, Fei Cao, Meizhen Song

“…Abstract Nitrogen (N) and phosphorus (P) are mineral nutrients essential for plant growth and development, playing a crucial role throughout the plant life cycle. …”
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TAC102 Is a Novel Component of the Mitochondrial Genome Segregation Machinery in Trypanosomes. by Roman Trikin, Nicholas Doiron, Anneliese Hoffmann, Beat Haenni, Martin Jakob, Achim Schnaufer, Bernd Schimanski, Benoît Zuber, Torsten Ochsenreiter

“…The protein is present throughout the cell cycle and is assembled into the newly developing TAC only after the pro-basal body has matured indicating a hierarchy in the assembly process. …”
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The characteristics of the winter durum wheat varieties according to grain quality and pasta properties by N. S. Kravchenko, N. E. Samofalova, I. M. Oldyreva, T. S. Makarova

“…Throughout the years of study, the varieties were characterized by high indices of dry pasta color (4–5 points). …”
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Numerical simulation of single well geothermal system based on the artificial geyser concept considering phase change and multiphysics coupling by Chen Ziming, Xiao Fei

“…Abstract A geothermal system based on the artificial geyser concept can be free of high-pressure circulation pump. The core component of this system is a flash steam chamber located at the high-temperature well bottom, where periodic spray and vaporization of fine droplets occur, thus generating high pressure to drive the vapor to rise through the well- insulated inner tube of a coaxial heat exchanger (CHE). …”
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Assessment of biophysical properties of the first-in-class anti-cancer IgE antibody drug MOv18 IgE demonstrates monomeric purity and stability by Paul Considine, Panida Punnabhum, Callum G. Davidson, Georgina B. Armstrong, Michaela Kreiner, Heather J. Bax, Jitesh Chauhan, James Spicer, Debra H. Josephs, Sophia N. Karagiannis, Gavin Halbert, Zahra Rattray

“…The first-in-class MOv18 IgE, recognizing the cancer-associated antigen folate receptor-alpha (FRα), completed a Phase 1 clinical trial in patients with solid tumors, showing early signs of efficacy at a low dose. The inaugural process development and scaled manufacture of MOv18 IgE for clinical testing were undertaken with little baseline knowledge about the solution phase behavior of recombinant IgE at dose-relevant concentrations. …”
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A contra-steric chemoselective hydrometallation strategy with bulky NHC for catalytic asymmetric branched allylamine synthesis by Weihao Chen, Zhifeng Zhang, Chun-Yu Ho

“…This study presents our efforts in this regard with broad scope using N-heterocyclic carbene (NHC), and establishes a chiral (NHC)Ni(II)-catalyzed intermolecular cross-hydroalkenylation system of enamine (alkenyl-carbamate/phthalimide) and α-olefin for the synthesis of highly substituted branched allylamines. A sterically adaptable chiral NHC-Ni(II) catalyst design with an open quadrant enhances interaction with the heteroatom on enamine, offering a precise chemo-, regio-, and enantioselective insertion control throughout the process in a mixture of olefins and allowing convergent synthesis. …”
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Measurement of Radioactive Levels of 137Cs in Environmental Aerosols in Beijing by Rui-lin GAN, Juan DU, Lu LIU, Peng GAO, Xiu-feng MA

“…Due to the detection limit of gamma spectrometer methods is high, suitable for high activity samples, while the detection limit of radiochemical analysis is low, suitable for most environmental samples. …”
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An Integrated Model for Circular Waste Management Using the Internet of Things, Semantic Web, and Gamification (Circonomy): Case Study in Indonesia by Vitri Tundjungsari, Bambang Purnomosidi Dwi Putranto, Muhamad Bahrul Ulum, Nizirwan Anwar

“… Abstract BackgroundThe problem of how to deal with waste is a global issue all countries face. Like many developing countries, Indonesia has inadequate infrastructure to process the extremely high volume of waste produced throughout the country and minimal public participation in proper waste management. …”
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Extreme Mediterranean cyclones and associated variables in an atmosphere-only vs. an ocean-coupled regional model by M. Chericoni, M. Chericoni, M. Chericoni, G. Fosser, E. Flaounas, G. Sannino, G. Sannino, A. Anav, A. Anav

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Тhe main patterns of forming the microelement composition of soils under mountain-meadow vegetation in the Western Caucasus by T. V. Degtyareva, A. A. Likhovid

“…It was established that the formation of the microelene composition of soils under the mountain-meadow vegetation in the highland zone of Arkhyz is determined by the special conditions inherent in this part of the Western Caucasus: a high level of solar insolation throughout the year, increased moisture and a large number of incoming organic residues in the soil. …”
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Energy-water usage and greenhouse gas emissions nexus of the natural rubber industry in Vietnam by Hong Dao Nguyen Pham, Takahiro Watari, Nhu Nguyet Phan, Minh Duc Tran, Lan Huong Nguyen, Masashi Hatamoto, Kazuaki Syutsubo, Takashi Yamaguchi

“…Our study identified three main sources of GHG emissions in the Vietnamese natural rubber industry: high electricity use during the SVR production process, vast ammonia requirements for the CL production process, and direct CH4 and CO2 emissions from the regulation tanks of the wastewater processes. …”
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Legionella pneumophila response to shifts in biofilm structure mediated by hydrodynamics by Ana Rosa Silva, C. William Keevil, Ana Pereira

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Students’ Mastering of Structural Analysis of Substance as a Method to Form Future Specialists’ Scientific Thinking. Part II by L. A. Baikova, M. A. Kosareva, E. A. Nikonenko, V. V. Vaitner, A. Majee

“…The key initial element of vocational training stimulating the formation of reflexive skills and scientific thinking of future experts is mastering by students of a categorical-conceptual framework of science, which is consistently and comprehensively revealed throughout a high school stage of education. The authors designated phases of development of scientific thinking (formal-logical, reflexive-theoretical, hypothetico-deductive thinking), which are not clearly differentiated due to interpenetration and entanglement of their components and identity of thought processes in terms of their speed and quality. …”
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Analyzing Repetitive Narrative Patterns in Samad Behrangi’s Stories by Moharram Rezayati kishekhaleh, Mina Mehr Afarin

“…Furthermore, the remarkably high frequency of the repetition process (777 occurrences) across 260 distinct repetitive types, predominantly in the form of complete repetition within Behrangi's 17 stories, stood as a hallmark of his approach to word and phrase selection in narrative construction. …”
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Adaptive Global Dense Nested Reasoning Network into Small Target Detection in Large-Scale Hyperspectral Remote Sensing Image by Siyu Zhan, Yuxuan Yang, Muge Zhong, Guoming Lu, Xinyu Zhou

“…The proposed method involves three key innovations. Firstly, we develop a high-dimensional, multi-layer nested U-Net that facilitates cross-layer feature transfer, preserving high-level features of small and dim targets throughout the network. …”
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Comparative simulation analysis of photonic ultrasound sensors based on silicon waveguides by Tabea Fünning, Martin Paul, Costanza Lucia Manganelli, Christian Wenger, Andreas Mai, Patrick Steglich

“…Abstract Pressure sensors based on photonic integrated circuits (PIC) offer the prospect of outstanding sensitivities, extreme miniaturization and have the potential for highly scalable production using CMOS compatible processing. …”
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Perspectives of Secondary School Educators Teaching Gender and Sexuality in Health Education by Emily Lockhart, Jennie Bickmore-Brand, Phil Doecke

“…High-quality health education in schools plays a critical role in the formation of young people by developing the attitudes, beliefs, and skills needed to adopt and maintain healthy behaviours throughout their lives. …”
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