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The linker histone chaperone Prothymosin α (PTMA) is essential for efficient DNA damage repair and the recruitment of PARP1
Published 2025-06-01“…Relative to the wild type, Ptma −/− cell lines displayed increased sensitivity to DNA-damaging agents. Conclusion We suggest that DNA damage alters the interaction of H1.0 with the nucleosome to allow the chaperone PTMA to bind and promote release of linker histones thereby initiating the local chromatin de-condensation necessary for the efficient recruitment of repair proteins such as PARP1. …”
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Damage Identification Using Measured and Simulated Guided Wave Damage Interaction Coefficients Predicted Ad Hoc by Deep Neural Networks
Published 2025-03-01“…This technique employs the so-called wave damage interaction coefficients (WDICs) as highly sensitive damage features that describe the unique scattering pattern around possible damage. …”
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Efficiency and safety of Vortioxetine in the treatment of depressive disorders in cardiac patients
Published 2023-06-01Get full text
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CLINICAL TESTS OF PROPHYLACTIC DRINK EFFICIENCY FOR WORKERS OF INDUSTRIAL ENTERPRISES
Published 2015-03-01“…The possible mechanisms of such influence connected with direct interaction of oxidizers with antioxidants, the influence of the latter on capture of free radicals and singlet oxygen, protective action aiming to prevent the contact of active forms of oxygen with biologically active components of a cell, replacement and reparation of the damaged ferment structures have been considered.…”
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Efficient use and development of wheel-working machines for the locomotive facility needs
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Time–Frequency Characteristics of Vehicle–Bridge Interaction System for Structural Damage Detection Using Multi-Synchrosqueezing Transform
Published 2025-07-01“…Numerical and experimental results demonstrate that the proposed method efficiently and accurately extracts the time-varying features of the vehicle–bridge interaction system, which could serve as potential indicators of structural damage in bridges.…”
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In-depth exploration of nanoparticles for enhanced nutrient use efficiency and abiotic stresses management: Present insights and future horizons
Published 2024-12-01“…NFs help reduce the environmental damage caused by traditional, inorganic fertilizers. …”
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The effect of Plant Growth Promoting Rhizohacteria on activities of antioxidative enzymes, physiological characteristics and root growth of four chickpea (Cicer arietinum L.) culti...
Published 2020-02-01“…In order to maintain or increase crop productivity it becomes necessary to evolve efficient low-cost technologies for abiotic stress management. …”
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DNA Damage prevention by the use of Computational Designed Microlpastics adsorbing Chemicals.
Published 2025-07-01“…Microplastics are one of these exogenous sources and characterized by their small size and high surface-area-to-volume ratio, have the ability to interact strongly with biological systems, leading to cytotoxicity, cell damage, and DNA mutations that increase cancer risk. …”
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Effects of fast and slow-wilting soybean genotypes on fall armyworm (Spodoptera frugiperda) growth and development
Published 2024-12-01“…This study aimed to examine the impact of FAW feeding on soybean accessions that vary in their water use efficiency (WUE) traits, by examining FAW growth and life history parameters along with plant growth response to pest damage. …”
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Interaction of reserves and osmoprotection in dwarf cashew clones under water stress
Published 2025-05-01“…The CCP76/BRS226 combination was efficient under water-restricted conditions (25 and 50 % of the ETc), as evidenced by a significant reduction in the oxidative damages to leaf membranes and a concomitant increase in osmoprotectants such as total free amino acids and proline. …”
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Formation Damage due to Drilling and Fracturing Fluids and Its Solution for Tight Naturally Fractured Sandstone Reservoirs
Published 2017-01-01“…Drilling and fracturing fluids can interact with reservoir rock and cause formation damage that impedes hydrocarbon production. …”
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Human cytomegalovirus gene UL76 induces IL-8 expression through activation of the DNA damage response.
Published 2013-09-01“…Hence, this work characterizes a new role of the activation of DNA Damage response in the context of host-pathogen interactions.…”
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